ES2902349T3 - Tratamiento de prurito colestásico - Google Patents

Tratamiento de prurito colestásico Download PDF

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Publication number
ES2902349T3
ES2902349T3 ES18811954T ES18811954T ES2902349T3 ES 2902349 T3 ES2902349 T3 ES 2902349T3 ES 18811954 T ES18811954 T ES 18811954T ES 18811954 T ES18811954 T ES 18811954T ES 2902349 T3 ES2902349 T3 ES 2902349T3
Authority
ES
Spain
Prior art keywords
pruritus
day
seladelpar
compound
cholestatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES18811954T
Other languages
English (en)
Spanish (es)
Inventor
Pol Boudes
Charles Mcwherter
Alexandra Steinberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CymaBay Therapeutics Inc
Original Assignee
CymaBay Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CymaBay Therapeutics Inc filed Critical CymaBay Therapeutics Inc
Application granted granted Critical
Publication of ES2902349T3 publication Critical patent/ES2902349T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Ladders (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES18811954T 2017-09-26 2018-09-24 Tratamiento de prurito colestásico Active ES2902349T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762563395P 2017-09-26 2017-09-26
PCT/US2018/052490 WO2019067373A1 (en) 2017-09-26 2018-09-24 TREATMENT OF CHOLESTATIC PRURIT

Publications (1)

Publication Number Publication Date
ES2902349T3 true ES2902349T3 (es) 2022-03-28

Family

ID=64564950

Family Applications (2)

Application Number Title Priority Date Filing Date
ES18811954T Active ES2902349T3 (es) 2017-09-26 2018-09-24 Tratamiento de prurito colestásico
ES21201888T Active ES3012120T3 (en) 2017-09-26 2018-09-24 Treatment of cholestatic pruritus with seladelpar

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES21201888T Active ES3012120T3 (en) 2017-09-26 2018-09-24 Treatment of cholestatic pruritus with seladelpar

Country Status (26)

Country Link
US (2) US20190105291A1 (enExample)
EP (3) EP3973959B8 (enExample)
JP (1) JP7023371B2 (enExample)
KR (1) KR102376794B1 (enExample)
CN (1) CN111132675B (enExample)
AU (2) AU2018342323B2 (enExample)
BR (1) BR112020005074A2 (enExample)
CA (1) CA3076614C (enExample)
CY (1) CY1124894T1 (enExample)
DK (1) DK3973959T3 (enExample)
ES (2) ES2902349T3 (enExample)
FI (1) FI3973959T3 (enExample)
HR (2) HRP20212010T1 (enExample)
HU (2) HUE070033T2 (enExample)
IL (2) IL273569B (enExample)
LT (2) LT3973959T (enExample)
MX (1) MX392537B (enExample)
PL (2) PL3687523T3 (enExample)
PT (2) PT3687523T (enExample)
RS (1) RS62790B1 (enExample)
SG (1) SG11202002253SA (enExample)
SI (2) SI3973959T1 (enExample)
SM (1) SMT202200171T1 (enExample)
UA (1) UA125600C2 (enExample)
WO (1) WO2019067373A1 (enExample)
ZA (1) ZA202001646B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10272058B2 (en) 2014-03-20 2019-04-30 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
HUE041733T2 (hu) 2014-03-20 2019-05-28 Cymabay Therapeutics Inc Intrahepatikus kolesztázisos betegségek kezelése
US12053445B2 (en) 2016-03-31 2024-08-06 Genfit Methods of treatment of cholestatic diseases
US10512622B2 (en) 2017-07-14 2019-12-24 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
CN114980876A (zh) * 2020-02-10 2022-08-30 基恩菲特公司 用艾拉菲诺治疗原发性胆汁性胆管炎
CN116490191A (zh) * 2020-10-20 2023-07-25 葛兰素史克知识产权第二有限公司 治疗胆汁淤积性瘙痒的方法
SI4225291T1 (sl) 2021-02-01 2024-07-31 CymaBay Therapeutics, Inc., Zdravljenje holangiopatij s seladelparjem
US20240252499A1 (en) 2023-01-29 2024-08-01 Cymabay Therapeutics, Inc. Treatment of uremic pruritus
CN120529903A (zh) 2023-01-29 2025-08-22 西玛贝医药公司 慢性瘙痒性皮肤病的治疗

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2539446C (en) 2003-09-19 2013-12-03 Janssen Pharmaceutica, N.V. 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
JO3006B1 (ar) 2005-09-14 2016-09-05 Janssen Pharmaceutica Nv املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك
HUE041733T2 (hu) 2014-03-20 2019-05-28 Cymabay Therapeutics Inc Intrahepatikus kolesztázisos betegségek kezelése
US20190076500A1 (en) * 2017-09-13 2019-03-14 Novartis Ag Combinations comprising fxr agonists

Also Published As

Publication number Publication date
IL273569B (en) 2021-12-01
BR112020005074A2 (pt) 2020-09-15
MX2020007273A (es) 2022-05-23
CA3076614A1 (en) 2019-04-04
SG11202002253SA (en) 2020-04-29
HUE057377T2 (hu) 2022-05-28
IL288340B1 (en) 2023-01-01
EP4523744A2 (en) 2025-03-19
HRP20250022T1 (hr) 2025-03-14
EP3687523A1 (en) 2020-08-05
SI3687523T1 (sl) 2022-05-31
AU2018342323A1 (en) 2020-04-16
CY1124894T1 (el) 2023-01-05
CA3076614C (en) 2023-02-07
EP3973959B8 (en) 2025-01-15
AU2021254641A1 (en) 2021-11-18
JP7023371B2 (ja) 2022-02-21
LT3687523T (lt) 2022-03-25
IL273569A (en) 2020-05-31
PL3687523T3 (pl) 2022-02-21
MX392537B (es) 2025-03-04
HRP20212010T1 (hr) 2022-04-01
US20210283078A1 (en) 2021-09-16
FI3973959T3 (fi) 2025-02-03
IL288340B2 (en) 2023-05-01
ZA202001646B (en) 2021-08-25
SI3973959T1 (sl) 2025-03-31
AU2018342323B2 (en) 2021-09-23
HUE070033T2 (hu) 2025-05-28
CN111132675A (zh) 2020-05-08
JP2020535225A (ja) 2020-12-03
SMT202200171T1 (it) 2022-05-12
LT3973959T (lt) 2025-01-10
PT3687523T (pt) 2021-12-06
ES3012120T3 (en) 2025-04-08
UA125600C2 (uk) 2022-04-27
CN111132675B (zh) 2023-04-25
NZ762976A (en) 2021-11-26
WO2019067373A1 (en) 2019-04-04
RU2020114644A (ru) 2021-10-27
AU2021254641B2 (en) 2022-02-24
KR102376794B1 (ko) 2022-03-18
RU2020114644A3 (enExample) 2022-02-14
DK3973959T3 (da) 2025-01-20
EP4523744A3 (en) 2025-06-04
PL3973959T3 (pl) 2025-03-24
US20190105291A1 (en) 2019-04-11
EP3973959B1 (en) 2024-12-11
PT3973959T (pt) 2025-01-24
EP3973959A1 (en) 2022-03-30
KR20200058458A (ko) 2020-05-27
RS62790B1 (sr) 2022-02-28
IL288340A (en) 2022-01-01
EP3687523B1 (en) 2021-11-03

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