KR102376794B1 - 담즙정체성 소양증의 치료 - Google Patents

담즙정체성 소양증의 치료 Download PDF

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Publication number
KR102376794B1
KR102376794B1 KR1020207011163A KR20207011163A KR102376794B1 KR 102376794 B1 KR102376794 B1 KR 102376794B1 KR 1020207011163 A KR1020207011163 A KR 1020207011163A KR 20207011163 A KR20207011163 A KR 20207011163A KR 102376794 B1 KR102376794 B1 KR 102376794B1
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South Korea
Prior art keywords
pruritus
pharmaceutical composition
day
composition according
celadelpa
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Korean (ko)
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KR20200058458A (ko
Inventor
뽈 부드
찰스 에이 맥위어터
알렉산드라 에스 스테인버그
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사이머베이 쎄라퓨틱스, 인코퍼레이티드
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Ladders (AREA)
KR1020207011163A 2017-09-26 2018-09-24 담즙정체성 소양증의 치료 Active KR102376794B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762563395P 2017-09-26 2017-09-26
US62/563,395 2017-09-26
PCT/US2018/052490 WO2019067373A1 (en) 2017-09-26 2018-09-24 TREATMENT OF CHOLESTATIC PRURIT

Publications (2)

Publication Number Publication Date
KR20200058458A KR20200058458A (ko) 2020-05-27
KR102376794B1 true KR102376794B1 (ko) 2022-03-18

Family

ID=64564950

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Application Number Title Priority Date Filing Date
KR1020207011163A Active KR102376794B1 (ko) 2017-09-26 2018-09-24 담즙정체성 소양증의 치료

Country Status (26)

Country Link
US (2) US20190105291A1 (enExample)
EP (3) EP3973959B8 (enExample)
JP (1) JP7023371B2 (enExample)
KR (1) KR102376794B1 (enExample)
CN (1) CN111132675B (enExample)
AU (2) AU2018342323B2 (enExample)
BR (1) BR112020005074A2 (enExample)
CA (1) CA3076614C (enExample)
CY (1) CY1124894T1 (enExample)
DK (1) DK3973959T3 (enExample)
ES (2) ES3012120T3 (enExample)
FI (1) FI3973959T3 (enExample)
HR (2) HRP20250022T1 (enExample)
HU (2) HUE057377T2 (enExample)
IL (2) IL273569B (enExample)
LT (2) LT3973959T (enExample)
MX (1) MX392537B (enExample)
PL (2) PL3687523T3 (enExample)
PT (2) PT3973959T (enExample)
RS (1) RS62790B1 (enExample)
SG (1) SG11202002253SA (enExample)
SI (2) SI3687523T1 (enExample)
SM (1) SMT202200171T1 (enExample)
UA (1) UA125600C2 (enExample)
WO (1) WO2019067373A1 (enExample)
ZA (1) ZA202001646B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10272058B2 (en) 2014-03-20 2019-04-30 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
PL3119384T3 (pl) 2014-03-20 2019-03-29 Cymabay Therapeutics, Inc. Leczenie wewnątrzwątrobowych chorób cholestatycznych
US12053445B2 (en) 2016-03-31 2024-08-06 Genfit Methods of treatment of cholestatic diseases
US10512622B2 (en) 2017-07-14 2019-12-24 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
KR20220140762A (ko) * 2020-02-10 2022-10-18 장피트 엘라피브라노에 의한 원발 담즙성 담관염의 치료
CN116490191A (zh) * 2020-10-20 2023-07-25 葛兰素史克知识产权第二有限公司 治疗胆汁淤积性瘙痒的方法
HUE066653T2 (hu) 2021-02-01 2024-08-28 Cymabay Therapeutics Inc Cholangiopathiák kezelése seladelparral
EP4654957A1 (en) 2023-01-29 2025-12-03 CymaBay Therapeutics, Inc. Treatment of uremic pruritus
KR20250139304A (ko) 2023-01-29 2025-09-23 사이머베이 쎄라퓨틱스, 인코퍼레이티드 만성 소양증 피부병의 치료

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1667964T3 (pl) 2003-09-19 2010-01-29 Janssen Pharmaceutica Nv Kwasy 4-((fenoksyalkilo)tio)-fenoksyoctowe i analogi
JO3006B1 (ar) 2005-09-14 2016-09-05 Janssen Pharmaceutica Nv املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك
PL3119384T3 (pl) * 2014-03-20 2019-03-29 Cymabay Therapeutics, Inc. Leczenie wewnątrzwątrobowych chorób cholestatycznych
US20200276178A1 (en) * 2017-09-13 2020-09-03 Novartis Ag Combinations comprising fxr agonists

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Jones 등, Hepatology. Volume 64, Issue 6, December 2016, 1123A~1124A, LB-9*
Jones 등, Lancet Gastroenterol Hepatol. 2017, 2, 716-726

Also Published As

Publication number Publication date
CY1124894T1 (el) 2023-01-05
ES3012120T3 (en) 2025-04-08
RU2020114644A3 (enExample) 2022-02-14
CN111132675B (zh) 2023-04-25
EP3973959A1 (en) 2022-03-30
EP3973959B1 (en) 2024-12-11
US20210283078A1 (en) 2021-09-16
JP2020535225A (ja) 2020-12-03
LT3687523T (lt) 2022-03-25
IL288340A (en) 2022-01-01
ZA202001646B (en) 2021-08-25
US20190105291A1 (en) 2019-04-11
JP7023371B2 (ja) 2022-02-21
PT3687523T (pt) 2021-12-06
SI3973959T1 (sl) 2025-03-31
WO2019067373A1 (en) 2019-04-04
IL288340B1 (en) 2023-01-01
EP3973959B8 (en) 2025-01-15
KR20200058458A (ko) 2020-05-27
HUE057377T2 (hu) 2022-05-28
RU2020114644A (ru) 2021-10-27
IL273569B (en) 2021-12-01
SI3687523T1 (sl) 2022-05-31
PL3973959T3 (pl) 2025-03-24
CA3076614A1 (en) 2019-04-04
BR112020005074A2 (pt) 2020-09-15
AU2021254641B2 (en) 2022-02-24
LT3973959T (lt) 2025-01-10
AU2021254641A1 (en) 2021-11-18
CA3076614C (en) 2023-02-07
UA125600C2 (uk) 2022-04-27
IL288340B2 (en) 2023-05-01
IL273569A (en) 2020-05-31
EP4523744A2 (en) 2025-03-19
HRP20250022T1 (hr) 2025-03-14
EP3687523A1 (en) 2020-08-05
MX2020007273A (es) 2022-05-23
MX392537B (es) 2025-03-04
PL3687523T3 (pl) 2022-02-21
AU2018342323A1 (en) 2020-04-16
SMT202200171T1 (it) 2022-05-12
PT3973959T (pt) 2025-01-24
EP3687523B1 (en) 2021-11-03
AU2018342323B2 (en) 2021-09-23
NZ762976A (en) 2021-11-26
HRP20212010T1 (hr) 2022-04-01
EP4523744A3 (en) 2025-06-04
RS62790B1 (sr) 2022-02-28
FI3973959T3 (fi) 2025-02-03
CN111132675A (zh) 2020-05-08
SG11202002253SA (en) 2020-04-29
HUE070033T2 (hu) 2025-05-28
ES2902349T3 (es) 2022-03-28
DK3973959T3 (da) 2025-01-20

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