ZA202001646B - Treatment of cholestatic pruritus - Google Patents

Treatment of cholestatic pruritus

Info

Publication number
ZA202001646B
ZA202001646B ZA2020/01646A ZA202001646A ZA202001646B ZA 202001646 B ZA202001646 B ZA 202001646B ZA 2020/01646 A ZA2020/01646 A ZA 2020/01646A ZA 202001646 A ZA202001646 A ZA 202001646A ZA 202001646 B ZA202001646 B ZA 202001646B
Authority
ZA
South Africa
Prior art keywords
treatment
cholestatic pruritus
cholestatic
pruritus
Prior art date
Application number
ZA2020/01646A
Other languages
English (en)
Inventor
Boudes Pol
A Mcwherter Charles
S Steinberg Alexandra
Original Assignee
Cymabay Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cymabay Therapeutics Inc filed Critical Cymabay Therapeutics Inc
Publication of ZA202001646B publication Critical patent/ZA202001646B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Ladders (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA2020/01646A 2017-09-26 2020-03-16 Treatment of cholestatic pruritus ZA202001646B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762563395P 2017-09-26 2017-09-26
PCT/US2018/052490 WO2019067373A1 (en) 2017-09-26 2018-09-24 TREATMENT OF CHOLESTATIC PRURIT

Publications (1)

Publication Number Publication Date
ZA202001646B true ZA202001646B (en) 2021-08-25

Family

ID=64564950

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2020/01646A ZA202001646B (en) 2017-09-26 2020-03-16 Treatment of cholestatic pruritus

Country Status (26)

Country Link
US (2) US20190105291A1 (enExample)
EP (3) EP3973959B8 (enExample)
JP (1) JP7023371B2 (enExample)
KR (1) KR102376794B1 (enExample)
CN (1) CN111132675B (enExample)
AU (2) AU2018342323B2 (enExample)
BR (1) BR112020005074A2 (enExample)
CA (1) CA3076614C (enExample)
CY (1) CY1124894T1 (enExample)
DK (1) DK3973959T3 (enExample)
ES (2) ES3012120T3 (enExample)
FI (1) FI3973959T3 (enExample)
HR (2) HRP20250022T1 (enExample)
HU (2) HUE057377T2 (enExample)
IL (2) IL273569B (enExample)
LT (2) LT3687523T (enExample)
MX (1) MX392537B (enExample)
PL (2) PL3973959T3 (enExample)
PT (2) PT3973959T (enExample)
RS (1) RS62790B1 (enExample)
SG (1) SG11202002253SA (enExample)
SI (2) SI3973959T1 (enExample)
SM (1) SMT202200171T1 (enExample)
UA (1) UA125600C2 (enExample)
WO (1) WO2019067373A1 (enExample)
ZA (1) ZA202001646B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10272058B2 (en) 2014-03-20 2019-04-30 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
WO2015143178A1 (en) 2014-03-20 2015-09-24 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
US12053445B2 (en) 2016-03-31 2024-08-06 Genfit Methods of treatment of cholestatic diseases
US10512622B2 (en) 2017-07-14 2019-12-24 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
IL294502A (en) * 2020-02-10 2022-09-01 Genfit Treatment of primary biliary cholangitis with elafibranor
CN116490191A (zh) * 2020-10-20 2023-07-25 葛兰素史克知识产权第二有限公司 治疗胆汁淤积性瘙痒的方法
JP7596548B2 (ja) 2021-02-01 2024-12-09 サイマベイ・セラピューティクス・インコーポレイテッド 胆管症の治療
AU2024212118A1 (en) 2023-01-29 2025-07-31 Cymabay Therapeutics, Inc. Treatment of uremic pruritus
US20240252500A1 (en) 2023-01-29 2024-08-01 Cymabay Therapeutics, Inc. Treatment of chronic pruritic dermatoses
CN121023009A (zh) * 2025-10-31 2025-11-28 浙江大学医学院附属妇产科医院(浙江省妇女医院、浙江省妇女保健院) 基于唾液样本的妊娠期肝内胆汁淤积症易感基因多重pcr—ngs筛查方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004285849B2 (en) 2003-09-19 2011-04-28 Janssen Pharmaceutica, N.V. 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
JO3006B1 (ar) 2005-09-14 2016-09-05 Janssen Pharmaceutica Nv املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك
WO2015143178A1 (en) 2014-03-20 2015-09-24 Cymabay Therapeutics, Inc. Treatment of intrahepatic cholestatic diseases
EP3681537A1 (en) * 2017-09-13 2020-07-22 Novartis AG Combinations comprising fxr agonists

Also Published As

Publication number Publication date
US20190105291A1 (en) 2019-04-11
LT3973959T (lt) 2025-01-10
US20210283078A1 (en) 2021-09-16
HUE070033T2 (hu) 2025-05-28
IL288340B2 (en) 2023-05-01
MX2020007273A (es) 2022-05-23
MX392537B (es) 2025-03-04
RS62790B1 (sr) 2022-02-28
EP3687523A1 (en) 2020-08-05
JP2020535225A (ja) 2020-12-03
FI3973959T3 (fi) 2025-02-03
SI3687523T1 (sl) 2022-05-31
IL273569B (en) 2021-12-01
CY1124894T1 (el) 2023-01-05
ES2902349T3 (es) 2022-03-28
UA125600C2 (uk) 2022-04-27
ES3012120T3 (en) 2025-04-08
HRP20212010T1 (hr) 2022-04-01
CN111132675B (zh) 2023-04-25
RU2020114644A (ru) 2021-10-27
EP3973959B1 (en) 2024-12-11
EP3973959B8 (en) 2025-01-15
AU2018342323B2 (en) 2021-09-23
EP4523744A3 (en) 2025-06-04
SI3973959T1 (sl) 2025-03-31
CA3076614C (en) 2023-02-07
SG11202002253SA (en) 2020-04-29
EP3687523B1 (en) 2021-11-03
NZ762976A (en) 2021-11-26
DK3973959T3 (da) 2025-01-20
IL288340B1 (en) 2023-01-01
IL288340A (en) 2022-01-01
KR20200058458A (ko) 2020-05-27
IL273569A (en) 2020-05-31
HUE057377T2 (hu) 2022-05-28
EP3973959A1 (en) 2022-03-30
PT3687523T (pt) 2021-12-06
PT3973959T (pt) 2025-01-24
AU2021254641B2 (en) 2022-02-24
LT3687523T (lt) 2022-03-25
AU2021254641A1 (en) 2021-11-18
BR112020005074A2 (pt) 2020-09-15
PL3973959T3 (pl) 2025-03-24
CN111132675A (zh) 2020-05-08
CA3076614A1 (en) 2019-04-04
JP7023371B2 (ja) 2022-02-21
AU2018342323A1 (en) 2020-04-16
WO2019067373A1 (en) 2019-04-04
SMT202200171T1 (it) 2022-05-12
EP4523744A2 (en) 2025-03-19
HRP20250022T1 (hr) 2025-03-14
PL3687523T3 (pl) 2022-02-21
KR102376794B1 (ko) 2022-03-18
RU2020114644A3 (enExample) 2022-02-14

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