ES2882631T3 - Enzimas sensibles a lactato estabilizadas, electrodos y sensores y procedimientos para fabricar y utilizar las mismas - Google Patents
Enzimas sensibles a lactato estabilizadas, electrodos y sensores y procedimientos para fabricar y utilizar las mismas Download PDFInfo
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- ES2882631T3 ES2882631T3 ES16812345T ES16812345T ES2882631T3 ES 2882631 T3 ES2882631 T3 ES 2882631T3 ES 16812345 T ES16812345 T ES 16812345T ES 16812345 T ES16812345 T ES 16812345T ES 2882631 T3 ES2882631 T3 ES 2882631T3
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- Prior art keywords
- lactate
- sensor
- enzyme
- stabilizing agent
- catalase
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Classifications
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
- C12Y111/01—Peroxidases (1.11.1)
- C12Y111/01006—Catalase (1.11.1.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
- C12Y113/12—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)(1.13.12)
- C12Y113/12004—Lactate 2-monooxygenase (1.13.12.4)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/904—Oxidoreductases (1.) acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/908—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
Landscapes
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- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Enzymes And Modification Thereof (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
Applications Claiming Priority (2)
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| US201562175910P | 2015-06-15 | 2015-06-15 | |
| PCT/US2016/037642 WO2016205378A1 (en) | 2015-06-15 | 2016-06-15 | Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same |
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| ES2882631T3 true ES2882631T3 (es) | 2021-12-02 |
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| ES16812345T Active ES2882631T3 (es) | 2015-06-15 | 2016-06-15 | Enzimas sensibles a lactato estabilizadas, electrodos y sensores y procedimientos para fabricar y utilizar las mismas |
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| US (2) | US9914952B2 (enExample) |
| EP (3) | EP4647504A3 (enExample) |
| JP (1) | JP6822981B2 (enExample) |
| CN (1) | CN107735027A (enExample) |
| AU (3) | AU2016280696B2 (enExample) |
| CA (1) | CA2987091A1 (enExample) |
| ES (1) | ES2882631T3 (enExample) |
| WO (1) | WO2016205378A1 (enExample) |
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| EP4647504A3 (en) * | 2015-06-15 | 2026-02-18 | Abbott Diabetes Care Inc. | Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same |
| DK3310800T3 (da) | 2015-06-19 | 2022-02-28 | Centurion Biopharma Corp | Leveringssystem til styret lægemiddelfrigivelse |
| FI3423591T3 (fi) | 2016-03-04 | 2024-02-01 | Abbott Diabetes Care Inc | Nad(p)-riippuvaisia responsiivisia entsyymejä, elektrodeja ja antureita ja menetelmiä niiden valmistamiseksi ja käyttämiseksi |
| PT3717503T (pt) | 2017-11-30 | 2024-01-16 | Ladrx Corp | Profármacos de ligação a albumina de derivados de auristatina e |
| JP7442821B2 (ja) | 2017-11-30 | 2024-03-05 | センチュリオン バイオファーマ コーポレイション | メイタンシノイド系薬物送達システム |
| EP3720957A4 (en) * | 2017-12-04 | 2021-09-22 | The General Hospital Corporation | EXTRACELLULAR REDOX ENZYME SYSTEM FOR DISEASE RELIEF |
| US12076145B2 (en) * | 2018-04-19 | 2024-09-03 | Abbott Diabetes Care Inc. | Lactate sensors and associated methods |
| WO2019216977A1 (en) * | 2018-05-08 | 2019-11-14 | Abbott Diabetes Care Inc. | Sensing systems and methods for identifying emotional stress events |
| EP4487774A3 (en) | 2019-01-28 | 2025-03-26 | Abbott Diabetes Care, Inc. | Analyte sensors employing multiple enzymes |
| AU2020419193B2 (en) | 2020-01-03 | 2024-07-04 | Abbott Diabetes Care Inc. | Sensor array systems and methods for detecting multiple analytes |
| US20230213499A1 (en) | 2020-02-21 | 2023-07-06 | Kikkoman Corporation | Device for evaluating state of sample, system containing same, method for evaluating state of sample and lactate dehydrogenase used therefor |
| CN111518862B (zh) * | 2020-06-09 | 2022-02-18 | 南京工业大学 | 一种乳酸氧化酶生物电极的制备方法 |
| US20240401002A1 (en) | 2021-08-03 | 2024-12-05 | Kikkoman Corporation | Novel flavin-dependent lactate dehydrogenase and method for improving stability of lactate dehydrogenase |
| AU2024335431A1 (en) | 2023-09-01 | 2026-01-22 | Abbott Diabetes Care Inc. | Sensor for detecting glucose and lactate and methods for determining aerobic and anaerobic thresholds |
| US20250299818A1 (en) | 2024-03-25 | 2025-09-25 | Abbott Diabetes Care Inc. | Deployment and use of a continuous analyte monitoring system for improved home monitoring and readmission optimization |
| CN121027260B (zh) * | 2025-10-31 | 2026-01-23 | 江苏跃凯生物技术有限公司 | 一种持续乳酸监测传感器及其制备方法 |
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| US9980669B2 (en) | 2011-11-07 | 2018-05-29 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods |
| CN104487565A (zh) * | 2012-05-03 | 2015-04-01 | 新加坡国立大学 | 一种通过非流失共价结合将酶结合于电极的无介体电化学葡萄糖检测过程及其产品 |
| WO2016065190A1 (en) | 2014-10-23 | 2016-04-28 | Abbott Diabetes Care Inc. | Electrodes having at least one sensing structure and methods for making and using the same |
| EP4647504A3 (en) * | 2015-06-15 | 2026-02-18 | Abbott Diabetes Care Inc. | Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same |
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2016
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- 2016-06-15 US US15/183,488 patent/US9914952B2/en active Active
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2018
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| AU2022201057A1 (en) | 2022-03-10 |
| US20160362716A1 (en) | 2016-12-15 |
| EP4647504A3 (en) | 2026-02-18 |
| AU2022201057B2 (en) | 2024-04-04 |
| WO2016205378A1 (en) | 2016-12-22 |
| AU2024204622A1 (en) | 2024-07-18 |
| US20180148758A1 (en) | 2018-05-31 |
| EP3307164A4 (en) | 2018-11-21 |
| AU2016280696B2 (en) | 2021-11-18 |
| AU2016280696A1 (en) | 2017-12-07 |
| EP4647504A2 (en) | 2025-11-12 |
| EP3307164A1 (en) | 2018-04-18 |
| JP6822981B2 (ja) | 2021-01-27 |
| EP3967227A1 (en) | 2022-03-16 |
| JP2018519507A (ja) | 2018-07-19 |
| US10392647B2 (en) | 2019-08-27 |
| EP3967227B1 (en) | 2025-07-30 |
| CA2987091A1 (en) | 2016-12-22 |
| US9914952B2 (en) | 2018-03-13 |
| EP3307164B1 (en) | 2021-05-12 |
| CN107735027A (zh) | 2018-02-23 |
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