ES2869343T3 - Composiciones para el tratamiento del cáncer - Google Patents
Composiciones para el tratamiento del cáncer Download PDFInfo
- Publication number
- ES2869343T3 ES2869343T3 ES12160586T ES12160586T ES2869343T3 ES 2869343 T3 ES2869343 T3 ES 2869343T3 ES 12160586 T ES12160586 T ES 12160586T ES 12160586 T ES12160586 T ES 12160586T ES 2869343 T3 ES2869343 T3 ES 2869343T3
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- Prior art keywords
- cancer
- day
- hydroxylase
- abiraterone acetate
- inhibitor
- Prior art date
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- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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| KR20200125776A (ko) * | 2006-08-25 | 2020-11-04 | 코우가 바이오테크놀로지, 인크. | 암을 치료하기 위한 방법 및 조성물 |
| US20080051380A1 (en) | 2006-08-25 | 2008-02-28 | Auerbach Alan H | Methods and compositions for treating cancer |
| US20090124587A1 (en) * | 2007-07-12 | 2009-05-14 | Auerbach Alan H | METHODS FOR TREATING CANCER USING 17alpha-HYDROXYLASE/C17,20-LYASE INHIBITORS |
| WO2009057795A2 (en) * | 2007-10-29 | 2009-05-07 | Takeda Pharmaceutical Company Limited | Pyrrolo [1,2-c] imidazole derivatives for use im the prophylaxis or treatment of cancer which is refractory to known cancer therapies |
| CN102558274B (zh) * | 2010-12-08 | 2014-10-15 | 深圳万乐药业有限公司 | 一种适合工业化生产醋酸阿比特龙的合成方法 |
| CN102558275A (zh) * | 2010-12-20 | 2012-07-11 | 天津药物研究院 | α型多晶型醋酸阿比特龙结晶、其制备方法、用途和药物组合物 |
| MX356704B (es) | 2011-01-11 | 2018-06-11 | Novartis Ag | Combinación. |
| JP6239497B2 (ja) | 2011-04-01 | 2017-11-29 | ジェネンテック， インコーポレイテッド | Ａｋｔ阻害剤化合物及びアビラテロンの組み合わせ、及び使用方法 |
| US20120295932A1 (en) * | 2011-05-17 | 2012-11-22 | Western Connecticut Health Network, Inc. | Method for the treatment of cancer |
| CN103070828B (zh) * | 2011-10-26 | 2016-01-27 | 山东新时代药业有限公司 | 一种含醋酸阿比特龙的固体分散体、片剂及其制备方法 |
| CN102336801B (zh) * | 2011-10-31 | 2013-05-15 | 南京卡文迪许生物工程技术有限公司 | 醋酸阿比特龙多晶型物和药用组合物 |
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| CA2872541A1 (en) * | 2012-06-06 | 2013-12-12 | Novartis Ag | Combination of a 17 -alpha -hydroxylase (c17, 20 - lyase) inhibitor and a specific pi-3k inhibitor for treating a tumor disease |
| UA117663C2 (uk) | 2012-09-26 | 2018-09-10 | Арагон Фармасьютікалз, Інк. | Антиандроген для лікування неметастатичного кастраційно-резистентного раку передміхурової залози |
| CN103800296A (zh) * | 2012-11-13 | 2014-05-21 | 重庆医药工业研究院有限责任公司 | 一种稳定的阿比特龙口服固体药物组合物及其制备方法 |
| JOP20200097A1 (ar) * | 2013-01-15 | 2017-06-16 | Aragon Pharmaceuticals Inc | معدل مستقبل أندروجين واستخداماته |
| MX2015013247A (es) * | 2013-03-15 | 2016-11-25 | Iceutica Inc | Formulacion de acetato de abiraterona. |
| US20150246060A1 (en) | 2013-03-15 | 2015-09-03 | Iceutica Inc. | Abiraterone Acetate Formulation and Methods of Use |
| MX2015014046A (es) * | 2013-04-04 | 2016-05-16 | Exelixis Inc | Combinaciones de farmacos para tratar cancer. |
| US20150157646A1 (en) | 2013-09-27 | 2015-06-11 | Iceutica Inc. | Abiraterone Steroid Formulation |
| EP4265300B1 (en) * | 2013-10-01 | 2025-12-10 | Novartis AG | Composition comprising a 17 a-hydroxylase/c17,20 lyase (cyp17a1) inhibitor and an akt inhibitor |
| BR112016006970A2 (pt) * | 2013-10-01 | 2017-08-01 | Novartis Ag | enzalutamida em combinação com afuresertib para o tratamento de câncer |
| CN104546745A (zh) * | 2013-10-14 | 2015-04-29 | 深圳海王药业有限公司 | 醋酸阿比特龙的片剂组合物及其制备工艺 |
| EP3280448B1 (en) * | 2015-04-10 | 2020-12-30 | Capsugel Belgium NV | Abiraterone acetate lipid formulations |
| SI3490560T1 (sl) | 2016-07-29 | 2025-04-30 | Janssen Pharmaceutica, N.V. | Niraparib za uporabo pri metodi zdravljenja raka prostate |
| JOP20190244A1 (ar) * | 2017-04-13 | 2019-10-13 | Janssen Pharmaceutica Nv | تركيبة علاجية لسرطان البروستاتا |
| BR112020007439A2 (pt) | 2017-10-16 | 2020-10-27 | Aragon Pharmaceuticals, Inc. | antiandrogênios para o tratamento de câncer de próstata resistente à castração não metastática |
| CN109718198A (zh) * | 2017-10-30 | 2019-05-07 | 浙江京新药业股份有限公司 | 一种治疗前列腺癌的注射剂及其制备方法 |
| KR102879575B1 (ko) * | 2019-03-06 | 2025-11-03 | 프로펠라 쎄라퓨틱스, 인크. | 아비라테론 프로드러그 |
| WO2021031991A1 (zh) * | 2019-08-16 | 2021-02-25 | 中国科学院分子细胞科学卓越创新中心 | 治疗激素依赖性疾病及减少激素依赖性疾病患者药物耐受的组合物和方法 |
| IL297338A (en) * | 2020-04-16 | 2022-12-01 | Tavanta Therapeutics Hungary Incorporated | Methods and compositions for treating prostate cancer |
| CN114560903B (zh) * | 2022-03-09 | 2023-08-01 | 绍兴市上虞区武汉理工大学高等研究院 | 一种阿比特龙衍生物的制备方法及其细胞毒性评价 |
| LU506495B1 (en) | 2024-03-01 | 2025-09-01 | Alfasan Nederland B V | 17alpha-HYDROXYLASE/17,20-LYASE (CYP17A1) INHIBITORS FOR THE TREATMENT OF SPONTANEOUS HYPERADRENOCORTICISM IN DOGS |
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| US5604213A (en) | 1992-03-31 | 1997-02-18 | British Technology Group Limited | 17-substituted steroids useful in cancer treatment |
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| AU2002219472A1 (en) * | 2001-01-02 | 2002-07-16 | Elisabeth Shanahan-Prendergast | Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens |
| DE60318092T2 (de) * | 2002-10-23 | 2008-11-27 | Pantarhei Bioscience B.V. | Pharmazeutische zusammensetzung enthaltend estetrolderivate und anwendung in der krebsbehandlung |
| US20050054620A1 (en) * | 2003-01-13 | 2005-03-10 | Koeffler H. Phillip | Paricalcitol as a chemotherapeutic agent |
| US20060030608A1 (en) * | 2004-08-04 | 2006-02-09 | Boehringer Ingelheim Pharmaceuticals, Inc. | Anti aromatase compounds pharmaceutical compositions and uses thereof |
| GB0418900D0 (en) * | 2004-08-24 | 2004-09-29 | Btg Int Ltd | Novel salt forms |
| KR20200125776A (ko) * | 2006-08-25 | 2020-11-04 | 코우가 바이오테크놀로지, 인크. | 암을 치료하기 위한 방법 및 조성물 |
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2018
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