ES2847853T3 - Composiciones oftálmicas que contienen óxido nítrico que libera prostamida - Google Patents
Composiciones oftálmicas que contienen óxido nítrico que libera prostamida Download PDFInfo
- Publication number
- ES2847853T3 ES2847853T3 ES19185400T ES19185400T ES2847853T3 ES 2847853 T3 ES2847853 T3 ES 2847853T3 ES 19185400 T ES19185400 T ES 19185400T ES 19185400 T ES19185400 T ES 19185400T ES 2847853 T3 ES2847853 T3 ES 2847853T3
- Authority
- ES
- Spain
- Prior art keywords
- composition according
- ophthalmic composition
- aqueous ophthalmic
- solution
- hydroxystearate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229960002470 bimatoprost Drugs 0.000 title description 21
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title description 6
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- SHBUUTHKGIVMJT-UHFFFAOYSA-N Hydroxystearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OO SHBUUTHKGIVMJT-UHFFFAOYSA-N 0.000 claims abstract description 94
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- 125000001453 quaternary ammonium group Chemical group 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
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- 210000003786 sclera Anatomy 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
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- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
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- 238000003892 spreading Methods 0.000 description 1
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- 239000000126 substance Substances 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
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- 235000002906 tartaric acid Nutrition 0.000 description 1
- 229960002494 tetracaine hydrochloride Drugs 0.000 description 1
- 229960002368 travoprost Drugs 0.000 description 1
- MKPLKVHSHYCHOC-AHTXBMBWSA-N travoprost Chemical compound CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COC1=CC=CC(C(F)(F)F)=C1 MKPLKVHSHYCHOC-AHTXBMBWSA-N 0.000 description 1
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- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
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- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Ophthalmology & Optometry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18290082 | 2018-07-12 |
Publications (1)
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| ES2847853T3 true ES2847853T3 (es) | 2021-08-04 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
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| ES19185400T Active ES2847853T3 (es) | 2018-07-12 | 2019-07-10 | Composiciones oftálmicas que contienen óxido nítrico que libera prostamida |
| ES20172140T Active ES3036636T3 (en) | 2018-07-12 | 2019-07-10 | Ophthalmic compositions containing a nitric oxide releasing prostamide |
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| Application Number | Title | Priority Date | Filing Date |
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| ES20172140T Active ES3036636T3 (en) | 2018-07-12 | 2019-07-10 | Ophthalmic compositions containing a nitric oxide releasing prostamide |
Country Status (28)
| Country | Link |
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| EP (2) | EP3718535B1 (https=) |
| JP (4) | JP6672512B2 (https=) |
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| CN (2) | CN111249228B (https=) |
| AR (1) | AR115734A1 (https=) |
| AU (2) | AU2019300203B2 (https=) |
| BR (1) | BR112021000240A2 (https=) |
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| ES (2) | ES2847853T3 (https=) |
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| HU (2) | HUE072927T2 (https=) |
| LT (1) | LT3593788T (https=) |
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| MX (2) | MX2021000411A (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| AU2019300203B2 (en) * | 2018-07-12 | 2025-01-30 | Nicox S.A. | Ophthalmic compositions containing a nitric oxide releasing prostamide |
| EP4404936A1 (en) * | 2021-09-20 | 2024-07-31 | Nicox SA | Nitric oxide releasing prostamide as neuroprotective agent |
| JP7665073B1 (ja) | 2024-04-05 | 2025-04-18 | ロート製薬株式会社 | 容器に収容してなる眼科用組成物 |
| US20260053768A1 (en) * | 2024-05-07 | 2026-02-26 | Maher Hadaya | Sustained Nitric Oxide Releasing Drug Delivery Systems |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2918891B1 (fr) | 2007-07-20 | 2009-09-25 | Thea Sa Lab | Solution ophtalmique a base de prostaglandines sans conservateur |
| US9629852B2 (en) | 2007-10-16 | 2017-04-25 | Sun Pharma Advanced Research Company Ltd. | Ophthalmic composition comprising a prostaglandin |
| AR076731A1 (es) | 2008-05-09 | 2011-07-06 | Pfizer | Prostamidas donadoras de oxido nitrico, uso de los mismos y composiciones farmaceuticas |
| MX2011002688A (es) | 2008-09-12 | 2011-04-12 | Critical Pharmaceuticals Ltd | Mejoramientos en la absorcion de agentes terapeuticos a traves de las membranas mucosas o la piel. |
| US20130267591A1 (en) * | 2010-05-07 | 2013-10-10 | Sun Pharma Advanced Research Company Limited | Novel ophthalmic compositions |
| FR2961694B1 (fr) * | 2010-06-29 | 2013-01-25 | Thea Lab | Systeme de delivrance polymerique d'une solution non visqueuse a base de prostaglandine sans conservateur |
| BR112013034051A2 (pt) * | 2011-06-29 | 2019-09-24 | Allergan Inc | formulações de macrogol 15 hidroxiestearato |
| CA2841644A1 (en) | 2011-08-02 | 2013-02-07 | Cipla Limited | Pharmaceutical composition comprising ebastine and fluticasone |
| CN105012231A (zh) * | 2014-04-30 | 2015-11-04 | 四川科伦药物研究院有限公司 | 一种包含PGF2α衍生物的稳定性良好的眼用制剂及其制备方法 |
| CN105380901B (zh) * | 2015-11-18 | 2018-07-17 | 侯宇华 | 一种他氟前列素滴眼剂及其制备方法 |
| AU2019300203B2 (en) * | 2018-07-12 | 2025-01-30 | Nicox S.A. | Ophthalmic compositions containing a nitric oxide releasing prostamide |
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2019
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2020
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2021
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2022
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2023
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