SG11202100064WA - Ophthalmic compositions containing a nitric oxide releasing prostamide - Google Patents

Ophthalmic compositions containing a nitric oxide releasing prostamide

Info

Publication number
SG11202100064WA
SG11202100064WA SG11202100064WA SG11202100064WA SG11202100064WA SG 11202100064W A SG11202100064W A SG 11202100064WA SG 11202100064W A SG11202100064W A SG 11202100064WA SG 11202100064W A SG11202100064W A SG 11202100064WA SG 11202100064W A SG11202100064W A SG 11202100064WA
Authority
SG
Singapore
Prior art keywords
prostamide
compositions containing
nitric oxide
ophthalmic compositions
oxide releasing
Prior art date
Application number
SG11202100064WA
Inventor
Frédéric Pilotaz
Alan L Weiner
Marina Do
Julien Saldo
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Publication of SG11202100064WA publication Critical patent/SG11202100064WA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
SG11202100064WA 2018-07-12 2019-07-10 Ophthalmic compositions containing a nitric oxide releasing prostamide SG11202100064WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18290082 2018-07-12
PCT/EP2019/068511 WO2020011845A1 (en) 2018-07-12 2019-07-10 Ophthalmic compositions containing a nitric oxide releasing prostamide

Publications (1)

Publication Number Publication Date
SG11202100064WA true SG11202100064WA (en) 2021-02-25

Family

ID=63012964

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202100064WA SG11202100064WA (en) 2018-07-12 2019-07-10 Ophthalmic compositions containing a nitric oxide releasing prostamide

Country Status (25)

Country Link
US (4) US10688073B2 (en)
EP (2) EP3718535A1 (en)
JP (4) JP6672512B2 (en)
KR (1) KR20210032435A (en)
CN (2) CN111249228B (en)
AR (1) AR115734A1 (en)
AU (1) AU2019300203A1 (en)
BR (1) BR112021000240A2 (en)
CA (1) CA3105989A1 (en)
CY (1) CY1123706T1 (en)
DK (1) DK3593788T3 (en)
ES (1) ES2847853T3 (en)
HR (1) HRP20210138T1 (en)
HU (1) HUE052747T2 (en)
LT (1) LT3593788T (en)
MA (2) MA52258A (en)
MD (1) MD3593788T2 (en)
MX (2) MX2021000411A (en)
PH (1) PH12020552112A1 (en)
PL (1) PL3593788T3 (en)
PT (1) PT3593788T (en)
RS (1) RS61348B1 (en)
SG (1) SG11202100064WA (en)
SI (1) SI3593788T1 (en)
WO (1) WO2020011845A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021000240A2 (en) * 2018-07-12 2021-04-06 Nicox S.A. OPHTHALMIC COMPOSITIONS CONTAINING A PROSTAMIDE THAT RELEASES NITRIC OXIDE
WO2023041182A1 (en) 2021-09-20 2023-03-23 Nicox Sa Nitric oxide releasing prostamide as neuroprotective agent

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2918891B1 (en) * 2007-07-20 2009-09-25 Thea Sa Lab OPHTHALMIC SOLUTION BASED ON PROSTAGLANDINS WITHOUT PRESERVATIVE
JP5646331B2 (en) * 2007-10-16 2014-12-24 サン、ファーマ、アドバンスト、リサーチ、カンパニー、リミテッドSun Pharma Advancedresearch Company Limited New ophthalmic composition
AR076731A1 (en) * 2008-05-09 2011-07-06 Pfizer GIVING PRESSURES OF NITRIC OXIDE, USE OF THE SAME AND PHARMACEUTICAL COMPOSITIONS
KR20110056516A (en) 2008-09-12 2011-05-30 크리티컬 파머수티컬스 리미티드 Improvements in the absorption of therapeutic agents across mucosal membranes or the skin
CN102970973A (en) * 2010-05-07 2013-03-13 太阳医药高级研发有限公司 Novel ophthalmic compositions
FR2961694B1 (en) * 2010-06-29 2013-01-25 Thea Lab POLYMERIC DELIVERY SYSTEM FOR NON-VISCOUS SOLUTION BASED ON PROSTAGLANDIN WITHOUT PRESERVATIVE
AU2012275115A1 (en) * 2011-06-29 2014-01-30 Allergan, Inc. Macrogol 15 hydroxystearate formulations
AU2012291841A1 (en) 2011-08-02 2014-02-06 Cipla Limited Pharmaceutical composition comprising ebastine and fluticasone
CN105012231A (en) * 2014-04-30 2015-11-04 四川科伦药物研究院有限公司 Good-stability eye-drop preparation containing PGF2alpha derivative and preparation method thereof
CN105380901B (en) * 2015-11-18 2018-07-17 侯宇华 A kind of tafluprost eye drops and preparation method thereof
BR112021000240A2 (en) * 2018-07-12 2021-04-06 Nicox S.A. OPHTHALMIC COMPOSITIONS CONTAINING A PROSTAMIDE THAT RELEASES NITRIC OXIDE

Also Published As

Publication number Publication date
CN111249228B (en) 2022-05-03
CN110237031B (en) 2022-02-11
CA3105989A1 (en) 2020-01-16
EP3718535A1 (en) 2020-10-07
MA52258A (en) 2021-02-17
RS61348B1 (en) 2021-02-26
HRP20210138T1 (en) 2021-03-19
DK3593788T3 (en) 2021-01-11
WO2020011845A1 (en) 2020-01-16
JP2022116147A (en) 2022-08-09
PL3593788T3 (en) 2021-05-31
JP2020105201A (en) 2020-07-09
CY1123706T1 (en) 2022-05-27
HUE052747T2 (en) 2021-05-28
JP6672512B2 (en) 2020-03-25
JP7397910B2 (en) 2023-12-13
MA48919B1 (en) 2021-02-26
US20210220316A1 (en) 2021-07-22
SI3593788T1 (en) 2021-03-31
MD3593788T2 (en) 2021-03-31
CN111249228A (en) 2020-06-09
US20200016108A1 (en) 2020-01-16
US11020368B2 (en) 2021-06-01
JP2024023498A (en) 2024-02-21
ES2847853T3 (en) 2021-08-04
LT3593788T (en) 2021-04-12
PT3593788T (en) 2021-01-21
MX2023007091A (en) 2023-06-27
MX2021000411A (en) 2021-03-25
US20200206176A1 (en) 2020-07-02
AU2019300203A1 (en) 2021-03-04
TW202019401A (en) 2020-06-01
US20210128458A1 (en) 2021-05-06
KR20210032435A (en) 2021-03-24
EP3593788B1 (en) 2020-10-28
JP2020011955A (en) 2020-01-23
JP7080268B2 (en) 2022-06-03
BR112021000240A2 (en) 2021-04-06
PH12020552112A1 (en) 2021-05-31
US10688073B2 (en) 2020-06-23
CN110237031A (en) 2019-09-17
AR115734A1 (en) 2021-02-17
EP3593788A1 (en) 2020-01-15
MA48919A (en) 2020-01-15

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