ES2833104T3 - Cepa que tiene una productividad aumentada de l-valina y método de producción de L-valina mediante el uso de la misma - Google Patents
Cepa que tiene una productividad aumentada de l-valina y método de producción de L-valina mediante el uso de la misma Download PDFInfo
- Publication number
- ES2833104T3 ES2833104T3 ES14764169T ES14764169T ES2833104T3 ES 2833104 T3 ES2833104 T3 ES 2833104T3 ES 14764169 T ES14764169 T ES 14764169T ES 14764169 T ES14764169 T ES 14764169T ES 2833104 T3 ES2833104 T3 ES 2833104T3
- Authority
- ES
- Spain
- Prior art keywords
- valine
- strain
- corynebacterium glutamicum
- leader peptide
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020130025528A KR101721722B1 (ko) | 2013-03-11 | 2013-03-11 | L-발린 생산능이 향상된 균주 및 이를 이용한 l-발린 생산방법 |
| PCT/KR2014/001793 WO2014142463A1 (ko) | 2013-03-11 | 2014-03-05 | L-발린 생산능이 향상된 균주 및 이를 이용한 l-발린 생산방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2833104T3 true ES2833104T3 (es) | 2021-06-14 |
Family
ID=51537057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14764169T Active ES2833104T3 (es) | 2013-03-11 | 2014-03-05 | Cepa que tiene una productividad aumentada de l-valina y método de producción de L-valina mediante el uso de la misma |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10072278B2 (de) |
| EP (1) | EP2975114B1 (de) |
| JP (1) | JP6359037B2 (de) |
| KR (1) | KR101721722B1 (de) |
| CN (1) | CN105026550B (de) |
| BR (1) | BR112015020274B1 (de) |
| ES (1) | ES2833104T3 (de) |
| HU (1) | HUE051725T2 (de) |
| MY (1) | MY175182A (de) |
| PH (1) | PH12015501906B1 (de) |
| WO (1) | WO2014142463A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101776375B1 (ko) | 2015-03-18 | 2017-09-08 | 씨제이제일제당 (주) | 피루브산 디하이드로게나아제 변이체, 이를 포함하는 미생물 및 이를 이용한 l-아미노산 생산 방법 |
| CN106190921B (zh) * | 2016-08-08 | 2019-07-26 | 天津科技大学 | 一种谷氨酸棒状杆菌与应用 |
| CN107287196B (zh) * | 2017-05-27 | 2020-05-26 | 中国科学院微生物研究所 | ilv衰减子的突变体、相关工程菌及其在生产缬氨酸中的应用 |
| US11021697B2 (en) | 2017-07-11 | 2021-06-01 | Cj Cheiljedang Corporation | Acetohydroxy acid synthase variant, microorganism comprising the same, and method of producing L-branched-chain amino acid using the same |
| KR101996129B1 (ko) * | 2017-07-11 | 2019-07-04 | 씨제이제일제당 (주) | 아세토하이드록시산 신타아제 변이체, 이를 포함하는 미생물 또는 이를 이용하는 l-분지쇄 아미노산 생산 방법 |
| KR102134418B1 (ko) * | 2019-06-17 | 2020-07-16 | 씨제이제일제당 주식회사 | L-타이로신을 생산하는 미생물 및 이를 이용한 l-타이로신 생산 방법 |
| KR102311391B1 (ko) | 2020-05-21 | 2021-10-12 | 씨제이제일제당 주식회사 | L- 분지쇄 아미노산 생산능이 강화된 미생물 및 이를 이용하여 l-분지쇄 아미노산을 생산하는 방법 |
| RU2753996C1 (ru) * | 2020-10-05 | 2021-08-25 | Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Национального исследовательского центра "Курчатовский институт" (НИЦ "Курчатовский институт" - ГосНИИгенетика) | Бактерия Corynebacterium glutamicum с повышенной способностью продуцировать L-валин и способ получения L-валина с использованием этой бактерии |
| KR102281366B1 (ko) * | 2021-01-26 | 2021-07-22 | 씨제이제일제당 (주) | 신규한 테트라하이드로디피콜리네이트 n-숙시닐트랜스퍼라제 변이체 및 이를 이용한 l-발린 생산 방법 |
| KR102281363B1 (ko) | 2021-01-26 | 2021-07-22 | 씨제이제일제당 (주) | 신규한 시스테인 설피네이트 디설피나제 변이체 및 이를 이용한 l-발린 생산 방법 |
| KR102281364B1 (ko) * | 2021-01-26 | 2021-07-22 | 씨제이제일제당 (주) | 신규한 우레아제 부속 단백질 변이체 및 이를 이용한 l-발린 생산 방법 |
| KR102281359B1 (ko) * | 2021-01-26 | 2021-07-22 | 씨제이제일제당 (주) | 신규한 단백질 변이체 및 이를 이용한 l-발린 생산 방법 |
| KR102281365B1 (ko) * | 2021-01-26 | 2021-07-22 | 씨제이제일제당 (주) | 신규한 프롤린 탈수소효소 변이체 및 이를 이용한 l-발린 생산 방법 |
| KR102281370B1 (ko) * | 2021-04-07 | 2021-07-22 | 씨제이제일제당 (주) | 신규한 2-이소프로필말레이트합성효소 변이체 및 이를 이용한 l-발린 생산 방법 |
| KR102281371B1 (ko) * | 2021-04-07 | 2021-07-22 | 씨제이제일제당 (주) | 신규한 글리세르알데히드-3-인산탈수소효소 변이체 및 이를 이용한 l-발린 생산 방법 |
| KR102306010B1 (ko) * | 2021-04-07 | 2021-09-27 | 씨제이제일제당 (주) | 신규한 분지쇄아미노산 투과효소 변이체 및 이를 이용한 l-발린 생산 방법 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR900007948B1 (ko) | 1988-12-12 | 1990-10-23 | 제일제당 주식회사 | 글루타민산을 생산하는 미생물 및 이를 이용한 글루타민산의 제조방법 |
| JP3709564B2 (ja) | 1994-08-30 | 2005-10-26 | 味の素株式会社 | Ｌ−バリン及びｌ−ロイシンの製造法 |
| RU2355763C2 (ru) * | 2006-09-13 | 2009-05-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | Мутантная ацетолактатсинтаза и способ продукции разветвленных l-аминокислот |
| US9109242B2 (en) | 2006-09-15 | 2015-08-18 | Cj Cheiljedang Corporation | Corynebacteria having enhanced L-lysine productivity and a method of producing L-lysine using the same |
| KR100832740B1 (ko) * | 2007-01-17 | 2008-05-27 | 한국과학기술원 | 분지쇄 아미노산 생성능이 개선된 변이 미생물 및 이를이용한 분지쇄 아미노산의 제조방법 |
| KR101117022B1 (ko) | 2011-08-16 | 2012-03-16 | 씨제이제일제당 (주) | Ｌ-발린 생산능이 향상된 미생물 및 이를 이용한 ｌ-발린 제조방법 |
-
2013
- 2013-03-11 KR KR1020130025528A patent/KR101721722B1/ko active IP Right Grant
-
2014
- 2014-03-05 CN CN201480013323.2A patent/CN105026550B/zh active Active
- 2014-03-05 US US14/771,969 patent/US10072278B2/en active Active
- 2014-03-05 ES ES14764169T patent/ES2833104T3/es active Active
- 2014-03-05 WO PCT/KR2014/001793 patent/WO2014142463A1/ko active Application Filing
- 2014-03-05 EP EP14764169.0A patent/EP2975114B1/de active Active
- 2014-03-05 HU HUE14764169A patent/HUE051725T2/hu unknown
- 2014-03-05 MY MYPI2015002297A patent/MY175182A/en unknown
- 2014-03-05 BR BR112015020274-8A patent/BR112015020274B1/pt active IP Right Grant
- 2014-03-05 JP JP2015557955A patent/JP6359037B2/ja active Active
-
2015
- 2015-08-28 PH PH12015501906A patent/PH12015501906B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR101721722B1 (ko) | 2017-04-10 |
| BR112015020274B1 (pt) | 2022-11-29 |
| EP2975114A4 (de) | 2016-11-09 |
| CN105026550B (zh) | 2019-09-20 |
| MY175182A (en) | 2020-06-12 |
| US20160108444A1 (en) | 2016-04-21 |
| EP2975114B1 (de) | 2020-09-30 |
| US10072278B2 (en) | 2018-09-11 |
| KR20140111421A (ko) | 2014-09-19 |
| JP2016506756A (ja) | 2016-03-07 |
| EP2975114A1 (de) | 2016-01-20 |
| HUE051725T2 (hu) | 2021-03-29 |
| JP6359037B2 (ja) | 2018-07-18 |
| CN105026550A (zh) | 2015-11-04 |
| PH12015501906A1 (en) | 2016-01-04 |
| WO2014142463A1 (ko) | 2014-09-18 |
| BR112015020274A2 (pt) | 2017-10-10 |
| PH12015501906B1 (en) | 2016-01-04 |
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