ES2817888T3 - Inhibidor de galactósido de galectina-3 y su uso para tratar fibrosis pulmonar - Google Patents
Inhibidor de galactósido de galectina-3 y su uso para tratar fibrosis pulmonar Download PDFInfo
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- ES2817888T3 ES2817888T3 ES13785446T ES13785446T ES2817888T3 ES 2817888 T3 ES2817888 T3 ES 2817888T3 ES 13785446 T ES13785446 T ES 13785446T ES 13785446 T ES13785446 T ES 13785446T ES 2817888 T3 ES2817888 T3 ES 2817888T3
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- compound
- galectin
- pulmonary fibrosis
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- lung
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Landscapes
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| CA2794066A CA2794066C (en) | 2012-10-31 | 2012-10-31 | Galactoside inhibitor of galectins |
| CA2795753A CA2795753A1 (en) | 2012-10-31 | 2012-11-15 | Novel galactoside inhibitor of galectins |
| US13/832,672 US9243021B2 (en) | 2012-10-31 | 2013-03-15 | Galactoside inhibitor of galectins |
| PCT/EP2013/072691 WO2014067986A1 (en) | 2012-10-31 | 2013-10-30 | Galactoside inhibitor of galectin-3 and its use for treating pulmonary fibrosis |
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| US9243021B2 (en) | 2012-10-31 | 2016-01-26 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| EP2620443A1 (en) | 2012-01-25 | 2013-07-31 | Galecto Biotech AB | Novel galactoside inhibitors of galectins |
| WO2016005311A1 (en) * | 2014-07-09 | 2016-01-14 | Galecto Biotech Ab | Novel hybrid galactoside inhibitor of galectins |
| EP3492484A1 (en) | 2015-01-16 | 2019-06-05 | Galecto Biotech AB | Novel galactoside inhibitor of galectins |
| US10774102B2 (en) * | 2015-01-30 | 2020-09-15 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| CA2983198C (en) | 2015-05-12 | 2022-07-19 | Galecto Biotech Ab | Once-daily treatment of pulmonary fibrosis |
| JP6915956B2 (ja) * | 2015-05-15 | 2021-08-11 | ガレクト・バイオテック・エイビイ | 肺線維症の１日１回の治療 |
| WO2017019770A1 (en) * | 2015-07-27 | 2017-02-02 | Wayne State University | Compositions and methods relating to galectin detection |
| ES2921500T3 (es) * | 2015-11-09 | 2022-08-26 | Galecto Biotech Ab | 1,1'-sulfanodiil-di-beta-d-galactopiranósidos como inhibidores de galectinas |
| CA3004632A1 (en) * | 2015-12-18 | 2017-06-22 | Galecto Biotech Ab | Polymorphic forms and process |
| US20190367552A1 (en) * | 2016-03-04 | 2019-12-05 | Galectin Sciences, Llc | Selenogalactoside compounds for the prevention and treatment of diseases associated with galectin and the use thereof |
| WO2018011093A1 (en) | 2016-07-12 | 2018-01-18 | Galecto Biotech Ab | Alpha-d-galactoside inhibitors of galectins |
| WO2018011094A1 (en) | 2016-07-12 | 2018-01-18 | Galecto Biotech Ab | Alpha-d-galactoside inhibitors of galectins |
| EP3621973A4 (en) * | 2017-05-12 | 2021-10-27 | Galectin Sciences, LLC | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF DISEASES AND USES THEREOF |
| US11267811B2 (en) | 2017-09-27 | 2022-03-08 | Bristol-Myers Squibb Company | Small molecule inhibitors of galectin-3 |
| WO2019075045A1 (en) | 2017-10-11 | 2019-04-18 | Bristol-Myers Squibb Company | INHIBITORS WITH SMALL MOLECULES OF GALECTIN-3 |
| CA3085356A1 (en) | 2017-12-29 | 2019-07-04 | Glycomimetics, Inc. | Heterobifunctional inhibitors of e-selectin and galectin-3 |
| CN111699193A (zh) | 2018-01-10 | 2020-09-22 | 格莱克特生物技术公司 | 新型半乳糖苷类半乳凝素抑制剂 |
| IL278761B2 (en) | 2018-05-17 | 2025-03-01 | Actuate Therapeutics Inc | Treatment of idiopathic pulmonary fibrosis with glycogen synthase kinase 3 form beta inhibitors |
| JP7190513B2 (ja) * | 2018-06-15 | 2022-12-15 | ブリストル－マイヤーズ スクイブ カンパニー | ガレクチン－３抑制剤を模したテトラヒドロピラン系チオ二糖類 |
| AU2019293857A1 (en) | 2018-06-29 | 2020-12-10 | Glykos Finland Oy | Conjugates |
| US12497428B2 (en) | 2018-10-15 | 2025-12-16 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| JP2022508719A (ja) | 2018-10-15 | 2022-01-19 | ガレクト バイオテック エービー | ガレクチンのガラクトシド阻害剤のプロドラッグ |
| EP3883946A1 (en) | 2018-11-21 | 2021-09-29 | Galecto Biotech AB | Alpha-d-galactoside inhibitors of galectins |
| JP2022511094A (ja) | 2018-12-06 | 2022-01-28 | ブリストル－マイヤーズ スクイブ カンパニー | ガレクチン－３の低分子阻害剤 |
| CN118373810A (zh) | 2018-12-27 | 2024-07-23 | 糖模拟物有限公司 | 抑制c-糖苷的半乳凝素-3 |
| US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
| US12275719B2 (en) | 2019-03-26 | 2025-04-15 | Bristol-Myers Squibb Company | Small molecule inhibitors of galectin-3 |
| JP7577682B2 (ja) | 2019-04-10 | 2024-11-05 | ブリストル－マイヤーズ スクイブ カンパニー | ガレクチン－３の低分子阻害剤 |
| WO2020248068A1 (en) | 2019-06-14 | 2020-12-17 | UNIVERSITé LAVAL | Synthesis of 3-azido-3-deoxy-d-galactopyranose |
| JP2022537737A (ja) | 2019-06-24 | 2022-08-29 | ガレクト バイオテック エービー | ３，３’－ジデオキシ－３，３’－ビス－［４－（３－フルオロフェニル）－１ｈ－１，２，３－トリアゾル－１－イル］－１，１’－スルファンジイル－ジ－ベータ－ｄ－ガラクトピラノシドの大規模方法 |
| CN114555620A (zh) | 2019-07-03 | 2022-05-27 | 格莱克特生物技术公司 | 半乳糖凝集素的新型半乳糖苷抑制剂 |
| CA3143079A1 (en) | 2019-07-03 | 2021-01-07 | Galecto Biotech Ab | Novel galactoside inhibitor of galectins |
| CA3143078A1 (en) | 2019-07-05 | 2021-01-14 | Galecto Biotech Ab | Novel galactoside inhibitor of galectins |
| ES2974680T3 (es) | 2019-08-09 | 2024-07-01 | Idorsia Pharmaceuticals Ltd | Derivados de (2-acetamidil)tio-beta-D-galactopiranósidos |
| KR102854071B1 (ko) | 2019-08-09 | 2025-09-02 | 이도르시아 파마슈티컬스 리미티드 | (헤테로)아릴-메틸-티오-베타-d-갈락토피라노시드 유도체 |
| MA56883B1 (fr) | 2019-08-15 | 2025-04-30 | Idorsia Pharmaceuticals Ltd | Dérivés de 2-hydroxycycloalcane-1-carbamoyle |
| JP7612669B2 (ja) | 2019-08-29 | 2025-01-14 | イドルシア・ファーマシューティカルズ・リミテッド | アルファ－ｄ－ガラクトピラノシド誘導体 |
| WO2021123506A1 (en) | 2019-12-18 | 2021-06-24 | Glykos Biomedical Oy | Stabile conjugate |
| US20230107479A1 (en) * | 2020-03-23 | 2023-04-06 | G3 Pharmaceuticals, Inc. | Methods and compositions for preventing and treating fibrosis resulting from a coronavirus infection |
| EP4126893A1 (en) | 2020-03-31 | 2023-02-08 | Galecto Biotech AB | Large scale process for preparing 1,2,4, 6-tetra-0-acetyl-3-azid0-3-de0xy-d-galact0pyran0side |
| WO2021226002A1 (en) | 2020-05-05 | 2021-11-11 | Bristol-Myers Squibb Company | Small molecule inhibitors of galectin-3 |
| US12286424B2 (en) | 2020-05-11 | 2025-04-29 | Bristol-Myers Squibb Company | Small molecule inhibitors of galectin-3 |
| EP4157833A1 (en) | 2020-05-28 | 2023-04-05 | Bristol-Myers Squibb Company | Galectin-3 inhibitors |
| KR20230083301A (ko) | 2020-10-06 | 2023-06-09 | 이도르시아 파마슈티컬스 리미티드 | 알파-d-갈락토피라노사이드의 스피로 유도체 |
| AU2021370994A1 (en) | 2020-11-02 | 2023-06-29 | Idorsia Pharmaceuticals Ltd | Galectin-3 inhibiting 2-hydroxycycloalkane-1 -carbamoyl derivatives |
| US12304902B2 (en) | 2021-02-09 | 2025-05-20 | Idorsia Pharmaceuticals Ltd | Hydroxyheterocycloalkane-carbamoyl derivatives |
| CA3209917A1 (en) | 2021-03-03 | 2022-09-09 | Martin Bolli | Triazolyl-methyl substituted alpha-d-galactopyranoside derivatives |
| WO2025111704A1 (en) * | 2023-12-01 | 2025-06-05 | UNIVERSITé LAVAL | Selective inhibitors of galectin-3 |
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| US5152456A (en) | 1989-12-12 | 1992-10-06 | Bespak, Plc | Dispensing apparatus having a perforate outlet member and a vibrating device |
| GB9027234D0 (en) | 1990-12-15 | 1991-02-06 | Harris Pharma Ltd | An inhalation device |
| ES2141108T3 (es) | 1991-07-02 | 2000-03-16 | Inhale Inc | Metodo y dispositivo para proporcionar medicamentos en aerosol. |
| KR19990077014A (ko) | 1996-01-03 | 1999-10-25 | 그레이엄 브레레톤 | 흡입 장치 |
| DE19726110C2 (de) | 1997-06-20 | 1999-07-22 | Draegerwerk Ag | Aerosolgenerator für Beatmungssysteme |
| US6962151B1 (en) | 1999-11-05 | 2005-11-08 | Pari GmbH Spezialisten für effektive Inhalation | Inhalation nebulizer |
| DE10102846B4 (de) | 2001-01-23 | 2012-04-12 | Pari Pharma Gmbh | Aerosolgenerator |
| DE50102690D1 (de) | 2001-10-18 | 2004-07-29 | Pari Gmbh | Inhalationstherapievorrichtung |
| US20060013775A1 (en) * | 2001-11-26 | 2006-01-19 | Gristwood Robert W | Use of ppar activators for the treatment of pulmonary fibrosis |
| EP1386672B1 (en) | 2002-08-02 | 2010-04-07 | PARI Pharma GmbH | Fluid droplet production apparatus |
| DE10250625A1 (de) | 2002-10-30 | 2004-05-19 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung |
| DE10257381B4 (de) | 2002-12-09 | 2006-09-14 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung |
| SE0401301D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel 3-triazolyl-galactoside inhibitors of galectins |
| SE0401300D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel Galactoside Inhibitors of Galectins |
| EP1782808A4 (en) * | 2004-07-22 | 2008-12-03 | Kaken Pharma Co Ltd | MEANS FOR THE PREVENTION OR TREATMENT OF CHRONIC INFLAMMATORY LUNG DISEASE |
| EP2424873B1 (en) | 2009-04-28 | 2017-11-15 | Galecto Biotech AB | Novel galactoside inhibitors of galectins |
| DE102009026636B4 (de) | 2009-06-02 | 2011-04-14 | Pari Pharma Gmbh | Verfahren zum Verschweißen einer Membran mit einem Träger bei der Herstellung eines Membranverneblers |
| JP6031510B2 (ja) * | 2011-04-12 | 2016-11-24 | モイライ マトリックス インコーポレイテッド | 異常な線維芽細胞増殖及び細胞外マトリックスの沈着を特徴とする疾患、症状又はプロセスを予防又は治療する組成物及び方法 |
-
2013
- 2013-10-30 IN IN2573DEN2015 patent/IN2015DN02573A/en unknown
- 2013-10-30 CA CA2884802A patent/CA2884802A1/en not_active Abandoned
- 2013-10-30 EP EP17183955.8A patent/EP3278805A1/en not_active Withdrawn
- 2013-10-30 JP JP2015538502A patent/JP2015535233A/ja active Pending
- 2013-10-30 WO PCT/EP2013/072691 patent/WO2014067986A1/en not_active Ceased
- 2013-10-30 EP EP13785446.9A patent/EP2914269B1/en active Active
- 2013-10-30 ES ES13785446T patent/ES2817888T3/es active Active
- 2013-10-30 CN CN201380057194.2A patent/CN104755088A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2884802A1 (en) | 2014-05-08 |
| WO2014067986A8 (en) | 2016-04-14 |
| IN2015DN02573A (cg-RX-API-DMAC10.html) | 2015-09-11 |
| EP2914269B1 (en) | 2020-07-29 |
| EP3278805A1 (en) | 2018-02-07 |
| JP2015535233A (ja) | 2015-12-10 |
| CN104755088A (zh) | 2015-07-01 |
| WO2014067986A1 (en) | 2014-05-08 |
| EP2914269A1 (en) | 2015-09-09 |
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