ES2817888T3 - Inhibidor de galactósido de galectina-3 y su uso para tratar fibrosis pulmonar - Google Patents
Inhibidor de galactósido de galectina-3 y su uso para tratar fibrosis pulmonar Download PDFInfo
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- ES2817888T3 ES2817888T3 ES13785446T ES13785446T ES2817888T3 ES 2817888 T3 ES2817888 T3 ES 2817888T3 ES 13785446 T ES13785446 T ES 13785446T ES 13785446 T ES13785446 T ES 13785446T ES 2817888 T3 ES2817888 T3 ES 2817888T3
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- compound
- galectin
- pulmonary fibrosis
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- lung
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- A61K9/007—Pulmonary tract; Aromatherapy
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- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
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Landscapes
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Applications Claiming Priority (5)
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| US201261720641P | 2012-10-31 | 2012-10-31 | |
| CA2794066A CA2794066C (en) | 2012-10-31 | 2012-10-31 | Galactoside inhibitor of galectins |
| CA2795753A CA2795753A1 (en) | 2012-10-31 | 2012-11-15 | Novel galactoside inhibitor of galectins |
| US13/832,672 US9243021B2 (en) | 2012-10-31 | 2013-03-15 | Galactoside inhibitor of galectins |
| PCT/EP2013/072691 WO2014067986A1 (en) | 2012-10-31 | 2013-10-30 | Galactoside inhibitor of galectin-3 and its use for treating pulmonary fibrosis |
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| ES13785446T Active ES2817888T3 (es) | 2012-10-31 | 2013-10-30 | Inhibidor de galactósido de galectina-3 y su uso para tratar fibrosis pulmonar |
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| CN (1) | CN104755088A (OSRAM) |
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| ES (1) | ES2817888T3 (OSRAM) |
| IN (1) | IN2015DN02573A (OSRAM) |
| WO (1) | WO2014067986A1 (OSRAM) |
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| US9243021B2 (en) | 2012-10-31 | 2016-01-26 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| EP2620443A1 (en) | 2012-01-25 | 2013-07-31 | Galecto Biotech AB | Novel galactoside inhibitors of galectins |
| EP3415522A1 (en) * | 2014-07-09 | 2018-12-19 | Galecto Biotech AB | Novel hybrid galactoside inhibitor of galectins |
| EP3492484A1 (en) | 2015-01-16 | 2019-06-05 | Galecto Biotech AB | Novel galactoside inhibitor of galectins |
| US10774102B2 (en) * | 2015-01-30 | 2020-09-15 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| ES2834644T3 (es) | 2015-05-12 | 2021-06-18 | Galecto Biotech Ab | Tratamiento una vez al día de la fibrosis pulmonar |
| JP6915956B2 (ja) * | 2015-05-15 | 2021-08-11 | ガレクト・バイオテック・エイビイ | 肺線維症の１日１回の治療 |
| WO2017019770A1 (en) * | 2015-07-27 | 2017-02-02 | Wayne State University | Compositions and methods relating to galectin detection |
| US10730902B2 (en) | 2015-11-09 | 2020-08-04 | Galecto Biotech Ab | 1,1 ′-sulfanediyl-di-beta-D-galactopyranosides as inhibitors of galectins |
| US10369136B2 (en) * | 2015-12-18 | 2019-08-06 | Galecto Biotech Ab | Polymorphic forms and process |
| MX394409B (es) * | 2016-03-04 | 2025-03-24 | Galectin Sciences Llc | Compuestos de seleno-galactosida para la prevención y el tratamiento de las enfermedades asociadas con galectina y el uso de los mismos. |
| JP7038099B2 (ja) | 2016-07-12 | 2022-03-17 | ガレクト バイオテック エービー | ガレクチンのα－Ｄ－ガラクトシド阻害剤 |
| CA3025867A1 (en) | 2016-07-12 | 2018-01-18 | Galecto Biotech Ab | Alpha-d-galactoside inhibitors of galectins |
| MX392945B (es) * | 2017-05-12 | 2025-03-19 | Galectin Sciences Llc | Compuestos para la prevencion y el tratamiento de enfermedades y el uso de los mismos. |
| WO2019067702A1 (en) | 2017-09-27 | 2019-04-04 | Bristol-Myers Squibb Company | INHIBITORS WITH SMALL MOLECULES OF GALECTIN-3 |
| WO2019075045A1 (en) | 2017-10-11 | 2019-04-18 | Bristol-Myers Squibb Company | INHIBITORS WITH SMALL MOLECULES OF GALECTIN-3 |
| KR20200104889A (ko) | 2017-12-29 | 2020-09-04 | 글리코미메틱스, 인크. | E-셀렉틴 및 갈렉틴-3의 이종이기능성 억제제 |
| EP3737686A1 (en) | 2018-01-10 | 2020-11-18 | Galecto Biotech AB | Novel galactoside inhibitor of galectins |
| CN112437663A (zh) * | 2018-05-17 | 2021-03-02 | 开动疗法公司 | 用β型糖原合酶激酶3抑制剂治疗特发性肺纤维化 |
| US11970511B2 (en) | 2018-06-15 | 2024-04-30 | Bristol-Myers Squibb Company | Tetrahydropyran-based thiodisaccharide mimics as Galectin-3 inhibitors |
| AU2019293857A1 (en) * | 2018-06-29 | 2020-12-10 | Glykos Finland Oy | Conjugates |
| EP3866925A1 (en) | 2018-10-15 | 2021-08-25 | Galecto Biotech AB | Prodrug of galactoside inhibitors of galectins |
| US12497428B2 (en) | 2018-10-15 | 2025-12-16 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| JP7486484B2 (ja) | 2018-11-21 | 2024-05-17 | ガレクト バイオテック エービー | ガレクチンのα－Ｄ－ガラクトシド阻害剤 |
| US12275718B2 (en) | 2018-12-06 | 2025-04-15 | Bristol-Myers Squibb Company | Small molecule inhibitors of galectin-3 |
| US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
| BR112021012482A2 (pt) | 2018-12-27 | 2021-09-08 | Glycomimetics, Inc. | C-glicosídeos inibidores de galectina-3 |
| WO2020198266A1 (en) | 2019-03-26 | 2020-10-01 | Bristol-Myers Squibb Company | Small molecule inhibitors of galectin-3 |
| US12269819B2 (en) | 2019-04-10 | 2025-04-08 | Bristol-Myers Squibb Company | Small molecule inhibitors of Galectin-3 |
| CA3138668A1 (en) | 2019-06-14 | 2020-12-17 | Denis Giguere | Synthesis of 3-azido-3-deoxy-d-galactopyranose |
| WO2020260351A1 (en) | 2019-06-24 | 2020-12-30 | Galecto Biotech Ab | Large scale process of 3,3'-dideoxy-3,3'-bis-[4-(3-fluorophenyl)-1h-1,2,3-triazol-1-yl]-1,1'-sulfanediyl-di-beta-d-galactopyranoside |
| US12441754B2 (en) | 2019-07-03 | 2025-10-14 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| JP7674275B2 (ja) | 2019-07-03 | 2025-05-09 | ガレクト バイオテック エービー | ガレクチンの新規なガラクトシド阻害剤 |
| EP3994135A1 (en) | 2019-07-05 | 2022-05-11 | Galecto Biotech AB | Novel galactoside inhibitor of galectins |
| ES2972509T3 (es) | 2019-08-09 | 2024-06-13 | Idorsia Pharmaceuticals Ltd | Derivados de (hetero)aril-metil-tio-beta-D-galactopiranósidos |
| EP4010348B1 (en) | 2019-08-09 | 2023-12-20 | Idorsia Pharmaceuticals Ltd | (2-acetamidyl)thio-beta-d-galactopyranoside derivatives |
| MA56883B1 (fr) | 2019-08-15 | 2025-04-30 | Idorsia Pharmaceuticals Ltd | Dérivés de 2-hydroxycycloalcane-1-carbamoyle |
| MX2022002339A (es) | 2019-08-29 | 2022-04-06 | Idorsia Pharmaceuticals Ltd | Derivados de alfa-d-galactopiranosido. |
| WO2021123506A1 (en) | 2019-12-18 | 2021-06-24 | Glykos Biomedical Oy | Stabile conjugate |
| US20230107479A1 (en) * | 2020-03-23 | 2023-04-06 | G3 Pharmaceuticals, Inc. | Methods and compositions for preventing and treating fibrosis resulting from a coronavirus infection |
| WO2021198160A1 (en) | 2020-03-31 | 2021-10-07 | Galecto Biotech Ab | Large scale process for preparing 1,2,4, 6-tetra-0-acetyl-3-azid0-3-de0xy-d-galact0pyran0side |
| EP4146646A1 (en) | 2020-05-05 | 2023-03-15 | Bristol-Myers Squibb Company | Small molecule inhibitors of galectin-3 |
| JP7677995B2 (ja) | 2020-05-11 | 2025-05-15 | ブリストル－マイヤーズ スクイブ カンパニー | ガレクチン－３の低分子阻害剤 |
| WO2021242982A1 (en) | 2020-05-28 | 2021-12-02 | Bristol-Myers Squibb Company | Galectin-3 inhibitors |
| TWI890869B (zh) | 2020-10-06 | 2025-07-21 | 瑞士商愛杜西亞製藥有限公司 | α-D-吡喃半乳糖苷之螺衍生物 |
| MX2023005039A (es) | 2020-11-02 | 2023-05-16 | Idorsia Pharmaceuticals Ltd | Derivados de 2-hidroxicicloalcan-1-carbamoilo que inhiben la galectina-3. |
| CA3207214A1 (en) | 2021-02-09 | 2022-08-18 | Martin Bolli | Hydroxyheterocycloalkane-carbamoyl derivatives |
| ES3033422T3 (en) | 2021-03-03 | 2025-08-04 | Idorsia Pharmaceuticals Ltd | Triazolyl-methyl substituted alpha-d-galactopyranoside derivatives |
| WO2025111704A1 (en) * | 2023-12-01 | 2025-06-05 | UNIVERSITé LAVAL | Selective inhibitors of galectin-3 |
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| DE3470380D1 (en) | 1984-08-09 | 1988-05-19 | Inge Brugger | Nebulizer |
| US5152456A (en) | 1989-12-12 | 1992-10-06 | Bespak, Plc | Dispensing apparatus having a perforate outlet member and a vibrating device |
| GB9027234D0 (en) | 1990-12-15 | 1991-02-06 | Harris Pharma Ltd | An inhalation device |
| ES2141108T3 (es) | 1991-07-02 | 2000-03-16 | Inhale Inc | Metodo y dispositivo para proporcionar medicamentos en aerosol. |
| ATE209939T1 (de) | 1996-01-03 | 2001-12-15 | Glaxo Group Ltd | Inhalator |
| DE19726110C2 (de) | 1997-06-20 | 1999-07-22 | Draegerwerk Ag | Aerosolgenerator für Beatmungssysteme |
| US6962151B1 (en) | 1999-11-05 | 2005-11-08 | Pari GmbH Spezialisten für effektive Inhalation | Inhalation nebulizer |
| DE10102846B4 (de) | 2001-01-23 | 2012-04-12 | Pari Pharma Gmbh | Aerosolgenerator |
| ATE269735T1 (de) | 2001-10-18 | 2004-07-15 | Pari Gmbh | Inhalationstherapievorrichtung |
| EP1465622A1 (en) * | 2001-11-26 | 2004-10-13 | Arachnova Therapeutics Ltd. | Use of ppar activators for the treatment of pulmonary fibrosis |
| ATE463304T1 (de) | 2002-08-02 | 2010-04-15 | Pari Pharma Gmbh | Vorrichtung zur erzeugung von flüssigkeitströpfchen |
| DE10250625A1 (de) | 2002-10-30 | 2004-05-19 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung |
| DE10257381B4 (de) | 2002-12-09 | 2006-09-14 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung |
| SE0401301D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel 3-triazolyl-galactoside inhibitors of galectins |
| SE0401300D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel Galactoside Inhibitors of Galectins |
| JPWO2006009209A1 (ja) * | 2004-07-22 | 2008-05-01 | 科研製薬株式会社 | 慢性炎症性肺疾患を予防もしくは治療する薬剤 |
| WO2010126435A1 (en) | 2009-04-28 | 2010-11-04 | Forskarpatent I Syd Ab | Novel galactoside inhibitors of galectins |
| DE102009026636B4 (de) | 2009-06-02 | 2011-04-14 | Pari Pharma Gmbh | Verfahren zum Verschweißen einer Membran mit einem Träger bei der Herstellung eines Membranverneblers |
| SG10201604560TA (en) * | 2011-04-12 | 2016-07-28 | Moerae Matrix Inc | Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition |
-
2013
- 2013-10-30 EP EP17183955.8A patent/EP3278805A1/en not_active Withdrawn
- 2013-10-30 ES ES13785446T patent/ES2817888T3/es active Active
- 2013-10-30 CA CA2884802A patent/CA2884802A1/en not_active Abandoned
- 2013-10-30 IN IN2573DEN2015 patent/IN2015DN02573A/en unknown
- 2013-10-30 WO PCT/EP2013/072691 patent/WO2014067986A1/en not_active Ceased
- 2013-10-30 JP JP2015538502A patent/JP2015535233A/ja active Pending
- 2013-10-30 CN CN201380057194.2A patent/CN104755088A/zh active Pending
- 2013-10-30 EP EP13785446.9A patent/EP2914269B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015535233A (ja) | 2015-12-10 |
| EP3278805A1 (en) | 2018-02-07 |
| IN2015DN02573A (OSRAM) | 2015-09-11 |
| EP2914269A1 (en) | 2015-09-09 |
| WO2014067986A8 (en) | 2016-04-14 |
| WO2014067986A1 (en) | 2014-05-08 |
| CA2884802A1 (en) | 2014-05-08 |
| CN104755088A (zh) | 2015-07-01 |
| EP2914269B1 (en) | 2020-07-29 |
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