ES2810906T3 - Derivados del di(fenilpropanoide) glicerol para el tratamiento del cáncer - Google Patents

Derivados del di(fenilpropanoide) glicerol para el tratamiento del cáncer Download PDF

Info

Publication number
ES2810906T3
ES2810906T3 ES10821532T ES10821532T ES2810906T3 ES 2810906 T3 ES2810906 T3 ES 2810906T3 ES 10821532 T ES10821532 T ES 10821532T ES 10821532 T ES10821532 T ES 10821532T ES 2810906 T3 ES2810906 T3 ES 2810906T3
Authority
ES
Spain
Prior art keywords
compound
cells
produce
cancer
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10821532T
Other languages
English (en)
Spanish (es)
Inventor
Alexander Macgregor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2810906T3 publication Critical patent/ES2810906T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
ES10821532T 2009-10-09 2010-10-08 Derivados del di(fenilpropanoide) glicerol para el tratamiento del cáncer Active ES2810906T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25028709P 2009-10-09 2009-10-09
PCT/CA2010/001613 WO2011041907A1 (en) 2009-10-09 2010-10-08 Derivatives of di(phenylpropanoid) glycerol for the treatment of cancer

Publications (1)

Publication Number Publication Date
ES2810906T3 true ES2810906T3 (es) 2021-03-09

Family

ID=43352967

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10821532T Active ES2810906T3 (es) 2009-10-09 2010-10-08 Derivados del di(fenilpropanoide) glicerol para el tratamiento del cáncer

Country Status (20)

Country Link
US (2) US9061993B2 (enExample)
EP (1) EP2486026B1 (enExample)
JP (1) JP5529280B2 (enExample)
CN (1) CN102264713A (enExample)
BR (1) BR112012008204A2 (enExample)
CA (1) CA2715662C (enExample)
CY (1) CY1123161T1 (enExample)
DK (1) DK2486026T3 (enExample)
ES (1) ES2810906T3 (enExample)
HR (1) HRP20201217T1 (enExample)
HU (1) HUE051549T2 (enExample)
LT (1) LT2486026T (enExample)
MX (1) MX360417B (enExample)
MY (2) MY160378A (enExample)
PL (1) PL2486026T3 (enExample)
PT (1) PT2486026T (enExample)
RS (1) RS60667B1 (enExample)
SI (1) SI2486026T1 (enExample)
SM (1) SMT202000428T1 (enExample)
WO (1) WO2011041907A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8907117B2 (en) * 2011-09-08 2014-12-09 Henry Lowe Anti-tumor and anti-inflammatory dicinnamoyl-glycerol esters and their analogues
US10092550B2 (en) 2014-10-21 2018-10-09 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof
US9402834B2 (en) 2014-10-21 2016-08-02 Ions Pharmaceutical S.À R.L. Human therapeutic agents
US9907786B2 (en) 2014-10-21 2018-03-06 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof
US12129265B2 (en) 2020-07-21 2024-10-29 Ankh Life Sciences Limited Therapeutic agents and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3857873A (en) 1974-02-11 1974-12-31 Warner Lambert Co 3-hydroxy-5-(3-(substituted-amino)-2-hydroxypropoxy)-benzyl alcohols
CH648753A5 (de) * 1981-07-22 1985-04-15 Givaudan & Cie Sa Lichtschutzmittel.
CN1238333C (zh) * 2003-06-18 2006-01-25 清华大学 药物化合物菠萝酰酯及其制备方法和用途
US7713556B2 (en) 2006-12-08 2010-05-11 Henry Lowe Anti-tumor and anti-inflammatory extracts of plant biomass and their uses
DK2104659T3 (en) * 2007-01-08 2015-11-02 Allianz Pharmascience Ltd Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and uses thereof
TWI383251B (zh) * 2008-01-16 2013-01-21 Eternal Chemical Co Ltd 感光型聚醯亞胺
KR101074149B1 (ko) * 2009-04-15 2011-10-17 한밭대학교 산학협력단 신규 폴리페놀/폴리페놀 컨쥬게이트 화합물 및 그의 용도
US8907117B2 (en) * 2011-09-08 2014-12-09 Henry Lowe Anti-tumor and anti-inflammatory dicinnamoyl-glycerol esters and their analogues

Also Published As

Publication number Publication date
LT2486026T (lt) 2020-09-10
PL2486026T3 (pl) 2020-11-02
HRP20201217T1 (hr) 2020-12-11
MX2012004160A (es) 2012-09-07
SI2486026T1 (sl) 2020-10-30
CY1123161T1 (el) 2021-10-29
WO2011041907A1 (en) 2011-04-14
MY160378A (en) 2017-03-15
HUE051549T2 (hu) 2021-10-28
US10052301B2 (en) 2018-08-21
PT2486026T (pt) 2020-08-21
EP2486026A1 (en) 2012-08-15
CA2715662A1 (en) 2010-12-14
US9061993B2 (en) 2015-06-23
RS60667B1 (sr) 2020-09-30
MX360417B (es) 2018-10-25
CN102264713A (zh) 2011-11-30
SMT202000428T1 (it) 2020-09-10
BR112012008204A2 (pt) 2017-07-18
CA2715662C (en) 2013-05-07
US20110086912A1 (en) 2011-04-14
JP5529280B2 (ja) 2014-06-25
EP2486026A4 (en) 2015-07-01
US20150246014A1 (en) 2015-09-03
DK2486026T3 (da) 2020-08-17
EP2486026B1 (en) 2020-06-24
MY187188A (en) 2021-09-09
JP2013507327A (ja) 2013-03-04

Similar Documents

Publication Publication Date Title
US6331559B1 (en) Lipoic acid derivatives and their use in treatment of disease
CA2911352A1 (en) Ester derivatives of androgen receptor modulators and methods for their use
Cao et al. Synthesis and biological evaluation of novel pyranochalcone derivatives as a new class of microtubule stabilizing agents
US10052301B2 (en) Derivatives of propane diyl dicinnamate
Naz et al. 4-Oxycoumarinyl linked acetohydrazide Schiff bases as potent urease inhibitors
Li et al. Discovery of oral-available resveratrol-caffeic acid based hybrids inhibiting acetylated and phosphorylated STAT3 protein
AU2008205312B2 (en) Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and uses thereof
CA2794266A1 (en) Compositions and methods for glucose transport inhibition
JP4677162B2 (ja) 増殖性障害を治療するための置換スチリルベンジルスルホン
JP7111730B2 (ja) ヒドロキシケイ皮酸誘導体、その方法および使用
JP2023051961A (ja) ヒドロキシ安息香酸誘導体、その方法および使用
CN107163011B (zh) 3-(3,4,5-三甲氧基苯甲酰)-苯并呋喃类微管蛋白抑制剂及其制备方法和用途
Bhaumik et al. Natural product inspired allicin analogs as novel anti-cancer agents
CN108299313B (zh) 一种化合物及其在药学上的应用
KR20170129688A (ko) 인돌아세트산의 코어구조를 함유하는 화합물 및 그의 용도
US20070191627A1 (en) Stilbene derivatives and their use in medicaments
JP7672153B2 (ja) クロメン系化合物、それらの方法及び使用
EP1268387B1 (en) Specific salt forms of triphenylethylene derivatives as selective estrogen receptor modulators
Wang et al. Crystal engineering construction of caffeic acid derivatives with potential applications in pharmaceuticals and degradable polymeric materials
HK1164842A (en) Derivatives of di(phenylpropanoid) glycerol for the treatment of cancer
CN101230015B (zh) 含酰胺取代基的取代桂皮酸衍生物及其肿瘤细胞毒性
CN113845484A (zh) 新型喹唑啉类小分子抑制剂及其在抗肿瘤药物中的应用
CN100596294C (zh) 4'-取代苄氧基-苯基丁二烯类衍生物及制备和用途
US8633242B2 (en) Benzylidene indanones and processes for preparation and use thereof
FR2996847A1 (fr) Composes 3,4-bis(catechol)pyrrole-n-substitues, leur preparation et utilisation dans le traitement du cancer