ES2803506T3 - Soluciones hipoosmóticas para la detección de ganglios linfáticos - Google Patents
Soluciones hipoosmóticas para la detección de ganglios linfáticos Download PDFInfo
- Publication number
- ES2803506T3 ES2803506T3 ES14711560T ES14711560T ES2803506T3 ES 2803506 T3 ES2803506 T3 ES 2803506T3 ES 14711560 T ES14711560 T ES 14711560T ES 14711560 T ES14711560 T ES 14711560T ES 2803506 T3 ES2803506 T3 ES 2803506T3
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- Prior art keywords
- hypoosmotic
- suspension
- mosm
- lymph node
- glycol
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- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1806—Suspensions, emulsions, colloids, dispersions
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
- A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
- A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
- A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
- A61K49/1851—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule
- A61K49/1863—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule the organic macromolecular compound being a polysaccharide or derivative thereof, e.g. chitosan, chitin, cellulose, pectin, starch
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/002—Magnetotherapy in combination with another treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
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- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Magnetic Treatment Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US201361775780P | 2013-03-11 | 2013-03-11 | |
| PCT/GB2014/050698 WO2014140543A1 (en) | 2013-03-11 | 2014-03-10 | Hypoosmotic solutions for lymph node detection |
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| ES2803506T3 true ES2803506T3 (es) | 2021-01-27 |
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| ES14711560T Active ES2803506T3 (es) | 2013-03-11 | 2014-03-10 | Soluciones hipoosmóticas para la detección de ganglios linfáticos |
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| WO2016154552A1 (en) * | 2015-03-25 | 2016-09-29 | Lodespin Labs, Llc | The use of iron oxide nanoparticles in magnetically guided sentinel lymph node biopsy |
| ES2833377T3 (es) | 2015-06-04 | 2021-06-15 | Endomagnetics Ltd | Materiales marcadores y formas de localizar un marcador magnético |
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2014
- 2014-03-10 CN CN201480013822.1A patent/CN105283202B/zh not_active Expired - Fee Related
- 2014-03-10 MX MX2015012587A patent/MX378185B/es unknown
- 2014-03-10 ES ES14711560T patent/ES2803506T3/es active Active
- 2014-03-10 JP JP2015562299A patent/JP6351639B2/ja active Active
- 2014-03-10 CA CA2904779A patent/CA2904779C/en active Active
- 2014-03-10 EP EP14711560.4A patent/EP2968560B1/en active Active
- 2014-03-10 WO PCT/GB2014/050698 patent/WO2014140543A1/en not_active Ceased
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|---|---|
| US20180028692A1 (en) | 2018-02-01 |
| MX378185B (es) | 2025-03-07 |
| BR112015022129B1 (pt) | 2022-04-19 |
| AU2014229811B2 (en) | 2018-02-15 |
| EP2968560B1 (en) | 2020-04-29 |
| BR112015022129A2 (pt) | 2017-07-18 |
| JP6351639B2 (ja) | 2018-07-04 |
| MX2015012587A (es) | 2016-10-13 |
| US20140314679A1 (en) | 2014-10-23 |
| AU2014229811A1 (en) | 2015-09-24 |
| CA2904779C (en) | 2019-04-09 |
| CA2904779A1 (en) | 2014-09-18 |
| US9808539B2 (en) | 2017-11-07 |
| EP2968560A1 (en) | 2016-01-20 |
| CN105283202B (zh) | 2019-04-23 |
| JP2016512221A (ja) | 2016-04-25 |
| CN105283202A (zh) | 2016-01-27 |
| WO2014140543A1 (en) | 2014-09-18 |
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