ES2793286T3 - Derivado de quinolina contra carcinoma de pulmón no microcítico - Google Patents
Derivado de quinolina contra carcinoma de pulmón no microcítico Download PDFInfo
- Publication number
- ES2793286T3 ES2793286T3 ES15867543T ES15867543T ES2793286T3 ES 2793286 T3 ES2793286 T3 ES 2793286T3 ES 15867543 T ES15867543 T ES 15867543T ES 15867543 T ES15867543 T ES 15867543T ES 2793286 T3 ES2793286 T3 ES 2793286T3
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- Prior art keywords
- compound
- pharmaceutically acceptable
- small cell
- administered
- acceptable salt
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| PCT/CN2015/096777 WO2016091168A1 (zh) | 2014-12-09 | 2015-12-09 | 抗非小细胞肺癌的喹啉衍生物 |
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| US10307412B2 (en) | 2014-12-09 | 2019-06-04 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Quinoline derivative against non-small cell lung cancer |
| US9751859B2 (en) | 2015-05-04 | 2017-09-05 | Advenchen Pharmaceuticals, LLC | Process for preparing an anti-cancer agent, 1-((4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropanamine, its crystalline form and its salts |
| AU2016293841B2 (en) | 2015-07-11 | 2020-10-08 | Advenchen Pharmaceuticals, LLC | Fused quinoline compunds as pi3k/mTor inhibitors |
| CN107296811B (zh) | 2016-04-15 | 2022-12-30 | 正大天晴药业集团股份有限公司 | 一种用于治疗胃癌的喹啉衍生物 |
| CN111936467B (zh) | 2018-03-02 | 2022-02-18 | 正大天晴药业集团股份有限公司 | 作为c-Met激酶抑制剂的化合物的结晶及其制备方法和用途 |
| WO2019223672A1 (zh) * | 2018-05-22 | 2019-11-28 | 正大天晴药业集团股份有限公司 | 用于治疗非小细胞肺癌的喹啉衍生物 |
| CN116077647B (zh) * | 2018-07-18 | 2025-06-27 | 正大天晴药业集团股份有限公司 | 喹啉衍生物与抗体的药物组合 |
| EP3854396A4 (en) * | 2018-09-18 | 2022-06-29 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Quinoline derivative used for treating small cell lung cancer |
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| CN112274511B (zh) * | 2019-07-22 | 2024-04-02 | 正大天晴药业集团股份有限公司 | 用于治疗移植物抗宿主病的喹啉衍生物 |
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| CN103974954B (zh) * | 2011-11-14 | 2016-08-24 | 北京赛林泰医药技术有限公司 | 调节激酶的化合物、含有它们的组合物及其用途 |
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| US10307412B2 (en) | 2014-12-09 | 2019-06-04 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Quinoline derivative against non-small cell lung cancer |
| US9751859B2 (en) | 2015-05-04 | 2017-09-05 | Advenchen Pharmaceuticals, LLC | Process for preparing an anti-cancer agent, 1-((4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropanamine, its crystalline form and its salts |
| AU2016293841B2 (en) | 2015-07-11 | 2020-10-08 | Advenchen Pharmaceuticals, LLC | Fused quinoline compunds as pi3k/mTor inhibitors |
| CN107296811B (zh) | 2016-04-15 | 2022-12-30 | 正大天晴药业集团股份有限公司 | 一种用于治疗胃癌的喹啉衍生物 |
-
2015
- 2015-12-09 US US15/533,873 patent/US10307412B2/en active Active
- 2015-12-09 WO PCT/CN2015/096777 patent/WO2016091168A1/zh not_active Ceased
- 2015-12-09 CN CN201580066275.8A patent/CN107001326B/zh active Active
- 2015-12-09 EP EP15867543.9A patent/EP3231797B1/en active Active
- 2015-12-09 JP JP2017530728A patent/JP6865684B2/ja active Active
- 2015-12-09 AU AU2015360095A patent/AU2015360095B2/en active Active
- 2015-12-09 ES ES15867543T patent/ES2793286T3/es active Active
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2019
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|---|---|
| US20190298712A1 (en) | 2019-10-03 |
| EP3231797B1 (en) | 2020-02-26 |
| WO2016091168A1 (zh) | 2016-06-16 |
| CN107001326A (zh) | 2017-08-01 |
| AU2015360095A1 (en) | 2017-07-27 |
| AU2015360095B2 (en) | 2020-02-27 |
| US10888559B2 (en) | 2021-01-12 |
| US20170304290A1 (en) | 2017-10-26 |
| EP3231797A4 (en) | 2018-05-09 |
| CN107001326B (zh) | 2020-05-05 |
| JP6865684B2 (ja) | 2021-04-28 |
| EP3231797A1 (en) | 2017-10-18 |
| US10307412B2 (en) | 2019-06-04 |
| JP2017537126A (ja) | 2017-12-14 |
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