ES274729A1 - Metodo para preparar preparaciones terapeuticas activas de acciën prolongada, para administraciën oral - Google Patents
Metodo para preparar preparaciones terapeuticas activas de acciën prolongada, para administraciën oralInfo
- Publication number
- ES274729A1 ES274729A1 ES0274729A ES274729A ES274729A1 ES 274729 A1 ES274729 A1 ES 274729A1 ES 0274729 A ES0274729 A ES 0274729A ES 274729 A ES274729 A ES 274729A ES 274729 A1 ES274729 A1 ES 274729A1
- Authority
- ES
- Spain
- Prior art keywords
- agent
- active material
- ingredients
- granulating
- solid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 239000011149 active material Substances 0.000 abstract 4
- 239000003979 granulating agent Substances 0.000 abstract 3
- 239000004615 ingredient Substances 0.000 abstract 3
- 239000011159 matrix material Substances 0.000 abstract 3
- 239000007787 solid Substances 0.000 abstract 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 239000000853 adhesive Substances 0.000 abstract 2
- 239000004411 aluminium Chemical class 0.000 abstract 2
- 229910052782 aluminium Chemical class 0.000 abstract 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical class [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000012530 fluid Substances 0.000 abstract 2
- 230000002496 gastric effect Effects 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 230000008961 swelling Effects 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- BALXUFOVQVENIU-GNAZCLTHSA-N Ephedrine hydrochloride Chemical compound Cl.CN[C@@H](C)[C@H](O)C1=CC=CC=C1 BALXUFOVQVENIU-GNAZCLTHSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000001856 Ethyl cellulose Substances 0.000 abstract 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 abstract 1
- 108010061711 Gliadin Proteins 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 108010068370 Glutens Proteins 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 229920002494 Zein Polymers 0.000 abstract 1
- RSWGJHLUYNHPMX-ONCXSQPRSA-N abietic acid Chemical compound C([C@@H]12)CC(C(C)C)=CC1=CC[C@@H]1[C@]2(C)CCC[C@@]1(C)C(O)=O RSWGJHLUYNHPMX-ONCXSQPRSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 229910052925 anhydrite Inorganic materials 0.000 abstract 1
- 230000036760 body temperature Effects 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 abstract 1
- OYACROKNLOSFPA-UHFFFAOYSA-N calcium;dioxido(oxo)silane Chemical compound [Ca+2].[O-][Si]([O-])=O OYACROKNLOSFPA-UHFFFAOYSA-N 0.000 abstract 1
- 229920002301 cellulose acetate Polymers 0.000 abstract 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 abstract 1
- 229910000397 disodium phosphate Inorganic materials 0.000 abstract 1
- 235000019800 disodium phosphate Nutrition 0.000 abstract 1
- 229960002534 ephedrine hydrochloride Drugs 0.000 abstract 1
- 229920001249 ethyl cellulose Polymers 0.000 abstract 1
- 235000019325 ethyl cellulose Nutrition 0.000 abstract 1
- 239000003925 fat Substances 0.000 abstract 1
- -1 for example Substances 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920000609 methyl cellulose Polymers 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000001923 methylcellulose Substances 0.000 abstract 1
- 235000010981 methylcellulose Nutrition 0.000 abstract 1
- 229960003941 orphenadrine Drugs 0.000 abstract 1
- QVYRGXJJSLMXQH-UHFFFAOYSA-N orphenadrine Chemical compound C=1C=CC=C(C)C=1C(OCCN(C)C)C1=CC=CC=C1 QVYRGXJJSLMXQH-UHFFFAOYSA-N 0.000 abstract 1
- 229960001687 orphenadrine citrate Drugs 0.000 abstract 1
- MMMNTDFSPSQXJP-UHFFFAOYSA-N orphenadrine citrate Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O.C=1C=CC=C(C)C=1C(OCCN(C)C)C1=CC=CC=C1 MMMNTDFSPSQXJP-UHFFFAOYSA-N 0.000 abstract 1
- 150000002942 palmitic acid derivatives Chemical class 0.000 abstract 1
- 229960002516 physostigmine salicylate Drugs 0.000 abstract 1
- HZOTZTANVBDFOF-PBCQUBLHSA-N physostigmine salicylate Chemical compound OC(=O)C1=CC=CC=C1O.C12=CC(OC(=O)NC)=CC=C2N(C)[C@@H]2[C@@]1(C)CCN2C HZOTZTANVBDFOF-PBCQUBLHSA-N 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 239000011118 polyvinyl acetate Substances 0.000 abstract 1
- 229920002689 polyvinyl acetate Polymers 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 239000011343 solid material Substances 0.000 abstract 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 abstract 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 abstract 1
- 235000019731 tricalcium phosphate Nutrition 0.000 abstract 1
- 239000001993 wax Substances 0.000 abstract 1
- 239000005019 zein Substances 0.000 abstract 1
- 229940093612 zein Drugs 0.000 abstract 1
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical class [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL261631 | 1961-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES274729A1 true ES274729A1 (es) | 1962-07-01 |
Family
ID=19752888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0274729A Expired ES274729A1 (es) | 1961-02-24 | 1962-02-20 | Metodo para preparar preparaciones terapeuticas activas de acciën prolongada, para administraciën oral |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3322633A (forum.php) |
| BE (1) | BE614070A (forum.php) |
| BR (1) | BR6236615D0 (forum.php) |
| CH (1) | CH445021A (forum.php) |
| DE (1) | DE1492045A1 (forum.php) |
| ES (1) | ES274729A1 (forum.php) |
| FI (1) | FI40197C (forum.php) |
| GB (1) | GB999959A (forum.php) |
| NL (1) | NL113366C (forum.php) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4137300A (en) * | 1976-08-20 | 1979-01-30 | Ciba-Geigy Corporation | Sustained action dosage forms |
| US4264573A (en) * | 1979-05-21 | 1981-04-28 | Rowell Laboratories, Inc. | Pharmaceutical formulation for slow release via controlled surface erosion |
| US4308251A (en) * | 1980-01-11 | 1981-12-29 | Boots Pharmaceuticals, Inc. | Controlled release formulations of orally-active medicaments |
| DK313381A (da) * | 1980-07-24 | 1982-01-25 | Mckechnike Chemicals Ltd | Reguleret frigoerelse af sporstoffer |
| US4704284A (en) * | 1982-08-12 | 1987-11-03 | Pfizer Inc. | Long-acting matrix tablet formulations |
| JPH0729927B2 (ja) * | 1983-04-09 | 1995-04-05 | 日研化学株式会社 | テオフィリン徐放性製剤 |
| FR2624010B1 (fr) * | 1987-12-07 | 1991-07-05 | Fabre Pierre Cosmetique | Compositions topiques heterogenes a base de microgranules de cafeine et/ou de ses derives, utiles comme amincissant et/ou dans le traitement de la cellulite, ainsi que leur preparation |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB837451A (en) * | 1956-02-20 | 1960-06-15 | Arner Co Inc | Sustained release therapeutic composition and process of preparing same |
| US3102845A (en) * | 1960-11-18 | 1963-09-03 | Mcneilab Inc | Pharmaceutical tablet |
-
0
- NL NL113366D patent/NL113366C/xx active
-
1962
- 1962-02-19 BE BE614070A patent/BE614070A/nl unknown
- 1962-02-20 ES ES0274729A patent/ES274729A1/es not_active Expired
- 1962-02-22 GB GB6923/62A patent/GB999959A/en not_active Expired
- 1962-02-22 BR BR136615/62A patent/BR6236615D0/pt unknown
- 1962-02-22 DE DE19621492045 patent/DE1492045A1/de active Pending
- 1962-02-23 FI FI38562A patent/FI40197C/fi active
- 1962-02-26 CH CH233962A patent/CH445021A/de unknown
-
1965
- 1965-01-11 US US424844A patent/US3322633A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| BE614070A (nl) | 1962-08-20 |
| BR6236615D0 (pt) | 1973-06-14 |
| NL113366C (forum.php) | |
| FI40197C (fi) | 1968-11-11 |
| FI40197B (forum.php) | 1968-07-31 |
| GB999959A (en) | 1965-07-28 |
| CH445021A (de) | 1967-10-15 |
| US3322633A (en) | 1967-05-30 |
| DE1492045A1 (de) | 1969-04-30 |
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