ES2742899T3 - Derivados de avermectina B1 que tienen un sustituyente alcoximetilo en la posición 4'' o 4' - Google Patents

Derivados de avermectina B1 que tienen un sustituyente alcoximetilo en la posición 4'' o 4' Download PDF

Info

Publication number
ES2742899T3
ES2742899T3 ES03810843T ES03810843T ES2742899T3 ES 2742899 T3 ES2742899 T3 ES 2742899T3 ES 03810843 T ES03810843 T ES 03810843T ES 03810843 T ES03810843 T ES 03810843T ES 2742899 T3 ES2742899 T3 ES 2742899T3
Authority
ES
Spain
Prior art keywords
spp
compounds
formula
substituents
avermectin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES03810843T
Other languages
English (en)
Spanish (es)
Inventor
Peter Maienfisch
Kessabi Fiona Murphy
Jérôme Cassayre
Laura Quaranta
Thomas Pitterna
Ottmar Franz Hueter
Pierre Jung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Animal Health USA Inc
Original Assignee
Boehringer Ingelheim Animal Health USA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Animal Health USA Inc filed Critical Boehringer Ingelheim Animal Health USA Inc
Application granted granted Critical
Publication of ES2742899T3 publication Critical patent/ES2742899T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/22Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom rings with more than six members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ES03810843T 2002-12-20 2003-12-19 Derivados de avermectina B1 que tienen un sustituyente alcoximetilo en la posición 4'' o 4' Expired - Lifetime ES2742899T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0229804.0A GB0229804D0 (en) 2002-12-20 2002-12-20 Avermection b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substituent in the 4"- or 4'-position
PCT/EP2003/014613 WO2004056844A1 (en) 2002-12-20 2003-12-19 Avermectin b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substituent in the 4”- or 4’-position

Publications (1)

Publication Number Publication Date
ES2742899T3 true ES2742899T3 (es) 2020-02-17

Family

ID=9950151

Family Applications (1)

Application Number Title Priority Date Filing Date
ES03810843T Expired - Lifetime ES2742899T3 (es) 2002-12-20 2003-12-19 Derivados de avermectina B1 que tienen un sustituyente alcoximetilo en la posición 4'' o 4'

Country Status (22)

Country Link
US (3) US7737261B2 (enExample)
EP (1) EP1581546B1 (enExample)
JP (2) JP4851094B2 (enExample)
KR (1) KR101109500B1 (enExample)
CN (1) CN1738828B (enExample)
AR (1) AR042533A1 (enExample)
AU (1) AU2003302284B2 (enExample)
BR (1) BR0317601A (enExample)
CA (1) CA2507774C (enExample)
CO (1) CO5690647A1 (enExample)
ES (1) ES2742899T3 (enExample)
GB (1) GB0229804D0 (enExample)
IL (1) IL169092A (enExample)
MA (1) MA27646A1 (enExample)
MX (1) MXPA05006036A (enExample)
PE (1) PE20040713A1 (enExample)
PL (1) PL211483B1 (enExample)
RU (1) RU2330857C2 (enExample)
TW (1) TW200512214A (enExample)
UA (1) UA81281C2 (enExample)
WO (1) WO2004056844A1 (enExample)
ZA (1) ZA200504353B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0229804D0 (en) * 2002-12-20 2003-01-29 Syngenta Participations Ag Avermection b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substituent in the 4"- or 4'-position
JP2010006703A (ja) * 2006-11-07 2010-01-14 Hokko Chem Ind Co Ltd アベルメクチンモノ配糖体誘導体
RU2472801C1 (ru) * 2011-05-11 2013-01-20 Игорь Викторович Заварзин 5-о-производные авермектина, способ их получения и антипаразитарные средства на их основе
RU2453553C1 (ru) * 2011-05-11 2012-06-20 Игорь Викторович Заварзин 5-о-сукциноилавермектин, способ его получения и антипаразитарное средство на его основе
CN103613625B (zh) * 2013-12-02 2016-03-02 兰州大学 一种阿维菌素类化合物及其制备方法和在农药中的用途
CN104402954A (zh) * 2014-11-28 2015-03-11 大庆志飞生物化工有限公司 甲胺基阿维菌素单糖化合物及其制备方法和用途
CN104402953B (zh) * 2014-11-28 2017-07-28 大庆志飞生物化工有限公司 阿维菌素单糖化合物及其制备方法和用途
JP6577184B2 (ja) 2014-12-24 2019-09-18 Ntn株式会社 転がり軸受
CN107501368B (zh) * 2017-09-30 2020-02-21 中国科学院成都生物研究所 一种多拉菌素衍生物的合成及其杀虫应用
CN113150053B (zh) * 2020-01-22 2024-10-01 华东理工大学 偶氮苯类阿维菌素衍生物及其制备方法和应用
CN113817008B (zh) * 2021-07-15 2023-05-23 湖州师范学院 新型琥珀酰基十六元大环内酯的制备方法及用途

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US87519A (en) * 1869-03-02 Improvement in furnace-stoves and registers
US148520A (en) * 1874-03-10 Improvement in faucets
US18993A (en) * 1857-12-29 Cider-mill
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4874749A (en) * 1987-07-31 1989-10-17 Merck & Co., Inc. 4"-Deoxy-4-N-methylamino avermectin Bla/Blb
GB8811037D0 (en) 1988-05-10 1988-06-15 Glaxo Group Ltd Chemical compounds
EP0353959A2 (en) 1988-08-02 1990-02-07 Beecham Group Plc Antihelmintic macrolide antibiotics
SE465605B (sv) * 1990-02-26 1991-10-07 Harry Nilsson Skivfilter
JP2622197B2 (ja) 1990-03-01 1997-06-18 三共株式会社 13−エーテル置換ミルベマイシン誘導体
US5169839A (en) * 1990-05-11 1992-12-08 Merck & Co., Inc. Derivatives of 3'- and 3"-o-desmethyl avermectin compounds, compositions and methods of treating melmintic and parasitic infections
US5262400A (en) * 1991-06-20 1993-11-16 Merck & Co., Inc. 4α-substituted avermectin derivatives
US5411737A (en) 1991-10-15 1995-05-02 Merck & Co., Inc. Slow release syneresing polymeric drug delivery device
US5602107A (en) 1993-05-10 1997-02-11 Merck & Co., Inc. Pour-on formulations consisting of gylcols, glycerides and avermectin compounds
PL174488B1 (pl) 1993-05-10 1998-08-31 Merck & Co Inc Preparat do zwalczania pasożytów zwierząt oraz sposób wytwarzania preparatu do zwalczania pasożytów zwierząt
AU684828B2 (en) * 1993-08-19 1998-01-08 Merck Sharp & Dohme Corp. Thermodynamically stable crystal form of 4"-deoxy-4"-(epi)-methylamino avermectin B1a/B1b benzoic acid salt and processes for its preparation
US5436355A (en) 1994-02-03 1995-07-25 Merck & Co., Inc. Process for making avermectin/zein compositions
TW327125B (en) 1994-02-07 1998-02-21 Merck & Co Inc Composition and method for protecting against pine exhausted
WO2002012248A1 (en) 2000-08-09 2002-02-14 The Kitasato Institute Avermectin derivatives
WO2002012261A1 (fr) 2000-08-09 2002-02-14 The Kitasato Institute Dérivés d'avermectine
CA2477614A1 (en) * 2002-03-05 2003-09-18 Merck & Co., Inc. Biomarker for efficacy of appetite suppressant drugs
GB0229804D0 (en) * 2002-12-20 2003-01-29 Syngenta Participations Ag Avermection b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substituent in the 4"- or 4'-position

Also Published As

Publication number Publication date
TW200512214A (en) 2005-04-01
JP2006515849A (ja) 2006-06-08
IL169092A (en) 2010-12-30
KR101109500B1 (ko) 2012-01-31
JP4851094B2 (ja) 2012-01-11
MXPA05006036A (es) 2005-08-18
US20100210574A1 (en) 2010-08-19
US8263566B2 (en) 2012-09-11
CA2507774A1 (en) 2004-07-08
WO2004056844A1 (en) 2004-07-08
CA2507774C (en) 2011-06-14
PL211483B1 (pl) 2012-05-31
UA81281C2 (en) 2007-12-25
KR20050088133A (ko) 2005-09-01
US20060148729A1 (en) 2006-07-06
BR0317601A (pt) 2005-11-29
RU2005122943A (ru) 2006-01-20
AR042533A1 (es) 2005-06-22
EP1581546B1 (en) 2019-03-20
CN1738828B (zh) 2012-09-05
GB0229804D0 (en) 2003-01-29
JP5302297B2 (ja) 2013-10-02
CO5690647A1 (es) 2006-10-31
US20110230429A1 (en) 2011-09-22
AU2003302284B2 (en) 2009-07-23
EP1581546A1 (en) 2005-10-05
JP2011102303A (ja) 2011-05-26
PE20040713A1 (es) 2004-12-02
RU2330857C2 (ru) 2008-08-10
PL377497A1 (pl) 2006-02-06
AU2003302284A1 (en) 2004-07-14
CN1738828A (zh) 2006-02-22
IL169092A0 (en) 2007-07-04
US8017589B2 (en) 2011-09-13
ZA200504353B (en) 2006-03-29
MA27646A1 (fr) 2005-12-01
US7737261B2 (en) 2010-06-15

Similar Documents

Publication Publication Date Title
US8263566B2 (en) Avermectin B1 and avermectin B1 monosaccharide derivatives having an alkoxymethyl substituent in the 4″-or 4′-position
EP1594878B1 (en) Avermectin monosaccharide derivatives having pesticidal properties
EP1613639B1 (en) Avermectins substituted in the 4'' and 4´-positions having pesticidal properties
US7632820B2 (en) Avermectin and avemectin monosaccharide derivatives substituted in the 4″- or 4′-position having pesticidal properties
US7704961B2 (en) Avermectins and avermectin monosacharides substituted in the 4′-and 4″ position having pesticidal properties
ES2293276T3 (es) Derivados de monosacaridos de la avermectina b1.
ES2407958T3 (es) Avermectinas y monosacáridos de avermectina sustituidos en la posición 4'y 4'' que tienen propiedades pesticidas