ES2742273T3 - Composiciones de crema farmacéuticas de oximetazolina para tratar los síntomas de la rosácea - Google Patents
Composiciones de crema farmacéuticas de oximetazolina para tratar los síntomas de la rosácea Download PDFInfo
- Publication number
- ES2742273T3 ES2742273T3 ES12705755T ES12705755T ES2742273T3 ES 2742273 T3 ES2742273 T3 ES 2742273T3 ES 12705755 T ES12705755 T ES 12705755T ES 12705755 T ES12705755 T ES 12705755T ES 2742273 T3 ES2742273 T3 ES 2742273T3
- Authority
- ES
- Spain
- Prior art keywords
- cream
- acid
- oxymetazoline
- weight
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161443210P | 2011-02-15 | 2011-02-15 | |
| PCT/US2012/025068 WO2012112566A1 (en) | 2011-02-15 | 2012-02-14 | Pharmaceutical cream compositions of oxymetazoline for treating symptoms of rosacea |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2742273T3 true ES2742273T3 (es) | 2020-02-13 |
Family
ID=45757218
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12705755T Active ES2742273T3 (es) | 2011-02-15 | 2012-02-14 | Composiciones de crema farmacéuticas de oximetazolina para tratar los síntomas de la rosácea |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US20120208858A1 (https=) |
| EP (2) | EP3578178B1 (https=) |
| JP (3) | JP6225030B2 (https=) |
| KR (2) | KR20190114010A (https=) |
| CN (2) | CN103458897A (https=) |
| AU (3) | AU2012217858A1 (https=) |
| BR (1) | BR112013020770A2 (https=) |
| CA (1) | CA2827373C (https=) |
| ES (1) | ES2742273T3 (https=) |
| RU (1) | RU2648439C2 (https=) |
| WO (1) | WO2012112566A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9486408B2 (en) | 2005-12-01 | 2016-11-08 | University Of Massachusetts Lowell | Botulinum nanoemulsions |
| MX2007009796A (es) | 2007-08-14 | 2009-02-25 | Cell Therapy And Technology S | Gel conteniendo pirfenidona. |
| BR112013020770A2 (pt) | 2011-02-15 | 2019-08-27 | Allergan, Inc. | composições de creme farmacêutico de oximetazolina para tratamento de sintomas de rosácea |
| US20120225918A1 (en) * | 2011-03-03 | 2012-09-06 | Voom, Llc | Compositions and Methods for Non-Surgical Treatment of Ptosis |
| MX2011007675A (es) | 2011-07-19 | 2012-07-11 | Cell Therapy And Technology S A De C V | Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas. |
| JP6174579B2 (ja) * | 2011-08-04 | 2017-08-02 | オメロス コーポレーション | 安定な注射用抗炎症性溶液 |
| MX357635B (es) | 2011-09-20 | 2018-07-17 | Allergan Inc | Composiciones y metodos para el tratamiento de presbicia, hipermetropia leve, y astigmatismo irregular. |
| MX346763B (es) | 2012-03-28 | 2017-03-31 | Cell Therapy And Tech S A De C V | Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné. |
| MX356551B (es) | 2012-08-23 | 2018-06-04 | Grupo Medifarma S A De C V Star | Composición antiséptica, antiseborreica y exfoliante para eliminar o prevenir el acné. |
| FR3000395A1 (fr) * | 2012-12-31 | 2014-07-04 | Galderma Res & Dev | Combinaison de laropiprant et d'oxymetazoline pour le traitement de la rosacee |
| AU2014212275B2 (en) | 2013-02-01 | 2018-09-06 | Ocuphire Pharma, Inc. | Methods and compositions for daily ophthalmic administration of phentolamine to improve visual performance |
| DK2950648T3 (da) | 2013-02-01 | 2019-12-02 | Ocuphire Pharma Inc | Vandige oftalmiske opløsninger af phentolamin og medicinske anvendelser deraf |
| WO2015062611A1 (en) * | 2013-10-28 | 2015-05-07 | Astion Pharma A/S | Compositions for dermatological use |
| AU2015252947B2 (en) * | 2014-05-01 | 2020-07-09 | Anterios, Inc. | Demonstrable efficacy across or within patient populations |
| MX379253B (es) | 2014-06-11 | 2025-03-11 | Epi Health Llc | Formulaciones de oximetazolina estabilizadas y sus usos. |
| WO2017049148A1 (en) * | 2015-09-17 | 2017-03-23 | June Jacobs Laboratiories, Llc | Compositions and methods for the treatment and prevention of radiation dermatitis |
| EP3476393A4 (en) * | 2016-06-28 | 2019-07-17 | Doris Maria Hexsel | USE OF AN ACTIVE AGENT FOR THE TREATMENT OF TELANGIEKTATISCHEM MELASMA |
| AU2017360346B2 (en) | 2016-11-21 | 2023-11-23 | Eirion Therapeutics, Inc. | Transdermal delivery of large agents |
| EA202090763A1 (ru) * | 2017-11-15 | 2020-08-03 | Борис Славинович ФАРБЕР | Фармацевтическая композиция для стимуляции деления стволовых клеток и подавления вирулентности бактерий |
| MX368750B (es) * | 2018-08-31 | 2019-10-15 | Cell Therapy And Tech S A De C V | Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular. |
| EP3866790A4 (en) | 2018-10-15 | 2022-08-03 | Ocuphire Pharma, Inc. | METHODS AND COMPOSITIONS FOR THE TREATMENT OF GLAUCOMA AND RELATED DISEASES |
| CA3116589A1 (en) | 2018-10-26 | 2020-04-30 | Ocuphire Pharma, Inc. | Methods and compositions for treatment of presbyopia, mydriasis, and other ocular disorders |
| AU2019390704A1 (en) * | 2018-11-26 | 2021-06-03 | Cellix Bio Private Limited | Ophthalmic compositions and methods for the treatment of skin diseases and eye diseases |
| CN111840287A (zh) * | 2019-04-30 | 2020-10-30 | 健艾仕生物医药有限公司 | 化合物在治疗炎症引起的自身免疫性皮肤病中的应用 |
| CN115368310B (zh) | 2021-05-18 | 2025-06-27 | 奥库菲尔医药公司 | 合成甲磺酸酚妥拉明的方法 |
| KR102633256B1 (ko) * | 2021-10-08 | 2024-02-05 | (주)우리스마트바이오 | 참당귀 추출물을 이용한 피부개선용 화장품 조성물, 이를 포함한 피부개선용 화장품 및 피부개선용 화장품 제조방법 |
| WO2023133199A1 (en) * | 2022-01-05 | 2023-07-13 | Asymmetric Therapeutics, Llc | Methods and compositions for treatment of cutaneous proliferative disorders and other skin conditions |
| US20240423959A1 (en) * | 2022-06-21 | 2024-12-26 | Jjr&D, Llc | Topical benzimidazole formulations and methods for use in treating inflammatory dermatoses |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3147275A (en) | 1964-09-01 | Nh-cha | ||
| US8093293B2 (en) * | 1998-07-06 | 2012-01-10 | Johnson & Johnson Consumer Companies, Inc. | Methods for treating skin conditions |
| US6433024B1 (en) | 2000-05-08 | 2002-08-13 | Karl F. Popp | Topical anti-acne composition |
| KR100898879B1 (ko) | 2000-08-16 | 2009-05-25 | 돌비 레버러토리즈 라이쎈싱 코오포레이션 | 부수 정보에 응답하여 하나 또는 그 이상의 파라메터를변조하는 오디오 또는 비디오 지각 코딩 시스템 |
| US6479060B1 (en) * | 2001-09-04 | 2002-11-12 | Healthpoint, Ltd. | Elegant hydrogenated castor oil ointments |
| US6824786B2 (en) | 2001-11-27 | 2004-11-30 | Ruey J. Yu | Compositions comprising phenyl-glycine derivatives |
| US6573301B1 (en) | 2002-04-23 | 2003-06-03 | Bradley Pharmaceuticals, Inc. | Carbamide peroxide compositions for the treatment of dermatological disorders and methods for their use |
| US7439241B2 (en) | 2003-05-27 | 2008-10-21 | Galderma Laboratories, Inc. | Compounds, formulations, and methods for treating or preventing rosacea |
| US7812049B2 (en) | 2004-01-22 | 2010-10-12 | Vicept Therapeutics, Inc. | Method and therapeutic/cosmetic topical compositions for the treatment of rosacea and skin erythema using α1-adrenoceptor agonists |
| JP4955543B2 (ja) * | 2004-05-25 | 2012-06-20 | サンズローザ ファーマシューティカル ディヴェロップメント インコーポレイテッド | 炎症性皮膚疾患を治療又は予防するための化合物、製剤及び方法 |
| CN101166535A (zh) | 2005-03-15 | 2008-04-23 | 坎皮纳荷兰控股有限责任公司 | 乳蛋白的皮肤病学应用 |
| JP5388568B2 (ja) * | 2005-03-30 | 2014-01-15 | ルバンス セラピュティックス インク． | ざ瘡を治療するための組成物及び方法 |
| KR101314689B1 (ko) | 2005-06-29 | 2013-10-07 | 디에스엠 아이피 어셋츠 비.브이. | 아이소플라본의 나노입자를 포함하는 국소용 조성물 |
| WO2007103687A2 (en) * | 2006-03-01 | 2007-09-13 | Tristrata, Inc. | Composition and method for topical treatment of tar-responsive dermatological disorders |
| US20080031979A1 (en) * | 2006-08-04 | 2008-02-07 | Claude Saliou | Use of extracts for the treatment of viral disorders |
| RU2310439C1 (ru) * | 2006-10-05 | 2007-11-20 | Закрытое акционерное общество Фармацевтическое научно-производственное предприятие "Ретиноиды" (ЗАО "Ретиноиды") | Мазевая акарицидная композиция и способ лечения демодекоза и сопутствующих ему заболеваний |
| US9511016B2 (en) * | 2007-06-12 | 2016-12-06 | Epicentrx, Inc. | Topical composition for treating pain |
| US20090061020A1 (en) | 2007-08-31 | 2009-03-05 | Theobald Klaus P | Brimonidine Compositions for Treating Erythema |
| JP5670196B2 (ja) | 2007-11-16 | 2015-02-18 | バイセプト セラピューティクス、インク． | 紫斑を治療する組成物および方法 |
| US20090130029A1 (en) * | 2007-11-21 | 2009-05-21 | Foamix Ltd. | Glycerol ethers vehicle and pharmaceutical compositions thereof |
| CA2779063A1 (en) | 2009-10-26 | 2011-05-05 | Galderma Pharma S.A. | Methods of treating or preventing acute erythema |
| US20120082625A1 (en) | 2010-09-28 | 2012-04-05 | Michael Graeber | Combination treatment for rosacea |
| JP6030067B2 (ja) * | 2010-12-03 | 2016-11-24 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | 薬学的クリーム組成物および使用法 |
| BR112013020770A2 (pt) | 2011-02-15 | 2019-08-27 | Allergan, Inc. | composições de creme farmacêutico de oximetazolina para tratamento de sintomas de rosácea |
| CN103796652A (zh) | 2011-07-14 | 2014-05-14 | 阿勒根公司 | 羟甲唑啉的凝胶组合物及使用方法 |
-
2012
- 2012-02-14 BR BR112013020770-1A patent/BR112013020770A2/pt not_active Application Discontinuation
- 2012-02-14 ES ES12705755T patent/ES2742273T3/es active Active
- 2012-02-14 EP EP19170085.5A patent/EP3578178B1/en active Active
- 2012-02-14 CA CA2827373A patent/CA2827373C/en active Active
- 2012-02-14 WO PCT/US2012/025068 patent/WO2012112566A1/en not_active Ceased
- 2012-02-14 EP EP12705755.2A patent/EP2675449B1/en active Active
- 2012-02-14 JP JP2013554551A patent/JP6225030B2/ja active Active
- 2012-02-14 RU RU2013141845A patent/RU2648439C2/ru active
- 2012-02-14 US US13/396,165 patent/US20120208858A1/en not_active Abandoned
- 2012-02-14 KR KR1020197028285A patent/KR20190114010A/ko not_active Withdrawn
- 2012-02-14 AU AU2012217858A patent/AU2012217858A1/en not_active Abandoned
- 2012-02-14 KR KR1020137024232A patent/KR102058756B1/ko active Active
- 2012-02-14 CN CN2012800179627A patent/CN103458897A/zh active Pending
- 2012-02-14 CN CN201710280045.2A patent/CN107007546A/zh active Pending
-
2013
- 2013-12-30 US US14/144,106 patent/US20140113947A1/en not_active Abandoned
-
2017
- 2017-01-10 JP JP2017002106A patent/JP6389534B2/ja active Active
- 2017-04-26 AU AU2017202726A patent/AU2017202726B2/en active Active
-
2018
- 2018-08-17 JP JP2018153450A patent/JP2018193399A/ja not_active Abandoned
-
2019
- 2019-02-05 US US16/267,590 patent/US20190167566A1/en not_active Abandoned
- 2019-06-07 AU AU2019203993A patent/AU2019203993B2/en active Active
- 2019-11-04 US US16/673,549 patent/US11541000B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20200276108A1 (en) | 2020-09-03 |
| AU2012217858A1 (en) | 2013-09-05 |
| US11541000B2 (en) | 2023-01-03 |
| CN103458897A (zh) | 2013-12-18 |
| JP6225030B2 (ja) | 2017-11-01 |
| CN107007546A (zh) | 2017-08-04 |
| EP2675449A1 (en) | 2013-12-25 |
| AU2019203993B2 (en) | 2020-05-28 |
| EP3578178A1 (en) | 2019-12-11 |
| KR102058756B1 (ko) | 2020-01-22 |
| RU2648439C2 (ru) | 2018-03-26 |
| AU2017202726B2 (en) | 2019-03-07 |
| CA2827373C (en) | 2019-05-14 |
| KR20190114010A (ko) | 2019-10-08 |
| JP2014505733A (ja) | 2014-03-06 |
| KR20140020912A (ko) | 2014-02-19 |
| US20140113947A1 (en) | 2014-04-24 |
| BR112013020770A2 (pt) | 2019-08-27 |
| EP2675449B1 (en) | 2019-04-24 |
| US20190167566A1 (en) | 2019-06-06 |
| JP2017066162A (ja) | 2017-04-06 |
| US20120208858A1 (en) | 2012-08-16 |
| JP6389534B2 (ja) | 2018-09-12 |
| AU2017202726A1 (en) | 2017-05-18 |
| CA2827373A1 (en) | 2012-08-23 |
| EP3578178B1 (en) | 2026-04-08 |
| AU2019203993A1 (en) | 2019-06-27 |
| WO2012112566A1 (en) | 2012-08-23 |
| JP2018193399A (ja) | 2018-12-06 |
| RU2013141845A (ru) | 2015-03-27 |
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