ES2729563T3 - Derivación sin alimentadores de células madre pluripotentes inducidas humanas con ARN mensajero sintético - Google Patents
Derivación sin alimentadores de células madre pluripotentes inducidas humanas con ARN mensajero sintético Download PDFInfo
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- ES2729563T3 ES2729563T3 ES13790064T ES13790064T ES2729563T3 ES 2729563 T3 ES2729563 T3 ES 2729563T3 ES 13790064 T ES13790064 T ES 13790064T ES 13790064 T ES13790064 T ES 13790064T ES 2729563 T3 ES2729563 T3 ES 2729563T3
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| US8497124B2 (en) | 2011-12-05 | 2013-07-30 | Factor Bioscience Inc. | Methods and products for reprogramming cells to a less differentiated state |
| AU2012347919B2 (en) | 2011-12-05 | 2017-02-02 | Factor Bioscience Inc. | Methods and products for transfecting cells |
| EP3561054B1 (en) * | 2012-05-13 | 2023-07-05 | Allele Biotechnology And Pharmaceuticals, Inc. | Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger rna |
| US10119150B2 (en) | 2012-05-13 | 2018-11-06 | Allele Biotechnology & Pharmaceuticals, Inc. | Feeder-free Derivation of human-induced pluripotent stem cells with synthetic messenger RNA |
| US10155929B2 (en) | 2012-05-13 | 2018-12-18 | Allele Biotechnology & Pharmaceuticals, Inc. | Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA |
| KR102121086B1 (ko) | 2012-11-01 | 2020-06-09 | 팩터 바이오사이언스 인크. | 세포에서 단백질을 발현시키는 방법들과 생성물들 |
| EP3099801B1 (en) | 2014-01-31 | 2020-03-18 | Factor Bioscience Inc. | Synthetic rna for use in the treatment of dystrophic epidermolysis bullosa |
| CA2976376A1 (en) | 2015-02-13 | 2016-08-18 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| CA3011692A1 (en) * | 2015-11-23 | 2017-06-01 | The Regents Of The University Of Colorado, A Body Corporate | Methods and compositions for reprogramming cells |
| IL308824A (en) | 2016-08-17 | 2024-01-01 | Factor Bioscience Inc | Nucleic acid products and methods of administration thereof |
| KR102586507B1 (ko) | 2016-11-16 | 2023-10-11 | 알렐 바이오테크놀로지 앤 파마슈티칼스, 인크. | Ｒｎａ를 사용한 줄기 세포 분화에 의한 간세포의 유도 |
| US12338462B2 (en) | 2016-11-16 | 2025-06-24 | Allele Biotechnology And Pharmaceuticals, Inc. | Induction of pancreatic beta cells by stem cell differentiation with RNA |
| KR102122336B1 (ko) * | 2018-10-26 | 2020-06-12 | 서울시립대학교 산학협력단 | 세포전환용 rna 나노입자를 이용한 유도만능줄기세포의 제조방법 |
| EP3969571A4 (en) | 2019-05-14 | 2023-05-24 | Aleph Farms Ltd. | PLURIPOTENTE CELL AGGREGATES AND THEIR USE |
| CA3145425A1 (en) | 2019-07-03 | 2021-01-07 | Factor Bioscience Inc. | Cationic lipids and uses thereof |
| US10501404B1 (en) | 2019-07-30 | 2019-12-10 | Factor Bioscience Inc. | Cationic lipids and transfection methods |
| WO2021149822A1 (ja) * | 2020-01-24 | 2021-07-29 | アイ ピース， インコーポレイテッド | 人工多能性幹細胞の作製方法 |
| JP2022104813A (ja) | 2020-12-29 | 2022-07-11 | アイ ピース，インコーポレイテッド | リプログラミング因子を導入された細胞の培養方法 |
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| EP3231869A1 (en) * | 2008-06-13 | 2017-10-18 | Whitehead Institute for Biomedical Research | Programming and reprogramming of cells |
| EP2881461A1 (en) * | 2008-11-21 | 2015-06-10 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Reprogramming cells toward a pluripotent state |
| WO2011056971A2 (en) * | 2009-11-04 | 2011-05-12 | Cellular Dynamics International, Inc. | Episomal reprogramming with chemicals |
| US8808982B2 (en) * | 2009-12-07 | 2014-08-19 | Cellscript, Llc | Compositions and methods for reprogramming eukaryotic cells |
| CN102190731B (zh) * | 2010-03-09 | 2016-01-27 | 中国科学院上海生命科学研究院 | 用人工转录因子诱导产生多能干细胞 |
| US9580689B2 (en) * | 2010-07-22 | 2017-02-28 | Regents Of The University Of Minnesota | Induced pluripotent stem cells |
| US8940945B2 (en) * | 2010-07-23 | 2015-01-27 | University Of South Florida | Materials and methods for reduction of protein tau and treatment of neurodegenerative diseases |
| CN102417894B (zh) * | 2011-10-21 | 2013-06-05 | 中国科学院广州生物医药与健康研究院 | 一种提高诱导生成多能性干细胞效率的方法 |
| EP3561054B1 (en) * | 2012-05-13 | 2023-07-05 | Allele Biotechnology And Pharmaceuticals, Inc. | Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger rna |
| US10155929B2 (en) * | 2012-05-13 | 2018-12-18 | Allele Biotechnology & Pharmaceuticals, Inc. | Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA |
| CN103739718B (zh) * | 2014-01-16 | 2017-02-08 | 中国科学院动物研究所 | 用于诱导多能干细胞的融合蛋白及其使用方法 |
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2017
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2019
- 2019-05-13 AU AU2019203335A patent/AU2019203335B2/en active Active
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| WO2013173248A3 (en) | 2014-12-18 |
| CA2872688A1 (en) | 2013-11-21 |
| HK1204005A1 (en) | 2015-11-06 |
| AU2019203335B2 (en) | 2021-10-21 |
| KR20150035594A (ko) | 2015-04-06 |
| CA2872688C (en) | 2023-09-19 |
| DK2850179T3 (da) | 2019-06-17 |
| AU2019203335A1 (en) | 2019-05-30 |
| AU2013263101B2 (en) | 2019-02-14 |
| JP2015517311A (ja) | 2015-06-22 |
| EP3561054C0 (en) | 2023-07-05 |
| AU2013263101A1 (en) | 2014-11-27 |
| ES2951822T3 (es) | 2023-10-25 |
| EP2850179A4 (en) | 2016-02-24 |
| EP2850179A2 (en) | 2015-03-25 |
| CN104520424A (zh) | 2015-04-15 |
| KR20200021553A (ko) | 2020-02-28 |
| JP6530452B2 (ja) | 2019-06-12 |
| EP3561054A1 (en) | 2019-10-30 |
| EP3561054B1 (en) | 2023-07-05 |
| JP2017184766A (ja) | 2017-10-12 |
| EP2850179B1 (en) | 2019-03-20 |
| CN104520424B (zh) | 2019-06-28 |
| JP6448531B2 (ja) | 2019-01-09 |
| KR102215413B1 (ko) | 2021-02-16 |
| KR102081811B1 (ko) | 2020-02-26 |
| CN110241087A (zh) | 2019-09-17 |
| CN110241087B (zh) | 2023-02-03 |
| WO2013173248A2 (en) | 2013-11-21 |
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