CN110241087B - 使用合成的信使rna无饲养细胞地衍生人类诱导性多能干细胞 - Google Patents

使用合成的信使rna无饲养细胞地衍生人类诱导性多能干细胞 Download PDF

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CN110241087B
CN110241087B CN201910468645.0A CN201910468645A CN110241087B CN 110241087 B CN110241087 B CN 110241087B CN 201910468645 A CN201910468645 A CN 201910468645A CN 110241087 B CN110241087 B CN 110241087B
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CN110241087A (zh
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王继武
鲁吉·瓦兰
倪毓辉
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Allele Biotechnology and Pharmaceuticals Inc
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CN201910468645.0A 2012-05-13 2013-05-13 使用合成的信使rna无饲养细胞地衍生人类诱导性多能干细胞 Active CN110241087B (zh)

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US201261646292P 2012-05-13 2012-05-13
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CN201380025010.4A CN104520424B (zh) 2012-05-13 2013-05-13 使用合成的信使rna无饲养细胞地衍生人类诱导性多能干细胞
PCT/US2013/040814 WO2013173248A2 (en) 2012-05-13 2013-05-13 Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger rna

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US8497124B2 (en) 2011-12-05 2013-07-30 Factor Bioscience Inc. Methods and products for reprogramming cells to a less differentiated state
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EP3561054B1 (en) * 2012-05-13 2023-07-05 Allele Biotechnology And Pharmaceuticals, Inc. Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger rna
US10119150B2 (en) 2012-05-13 2018-11-06 Allele Biotechnology & Pharmaceuticals, Inc. Feeder-free Derivation of human-induced pluripotent stem cells with synthetic messenger RNA
US10155929B2 (en) 2012-05-13 2018-12-18 Allele Biotechnology & Pharmaceuticals, Inc. Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA
KR102121086B1 (ko) 2012-11-01 2020-06-09 팩터 바이오사이언스 인크. 세포에서 단백질을 발현시키는 방법들과 생성물들
EP3099801B1 (en) 2014-01-31 2020-03-18 Factor Bioscience Inc. Synthetic rna for use in the treatment of dystrophic epidermolysis bullosa
CA2976376A1 (en) 2015-02-13 2016-08-18 Factor Bioscience Inc. Nucleic acid products and methods of administration thereof
CA3011692A1 (en) * 2015-11-23 2017-06-01 The Regents Of The University Of Colorado, A Body Corporate Methods and compositions for reprogramming cells
IL308824A (en) 2016-08-17 2024-01-01 Factor Bioscience Inc Nucleic acid products and methods of administration thereof
KR102586507B1 (ko) 2016-11-16 2023-10-11 알렐 바이오테크놀로지 앤 파마슈티칼스, 인크. Ｒｎａ를 사용한 줄기 세포 분화에 의한 간세포의 유도
US12338462B2 (en) 2016-11-16 2025-06-24 Allele Biotechnology And Pharmaceuticals, Inc. Induction of pancreatic beta cells by stem cell differentiation with RNA
KR102122336B1 (ko) * 2018-10-26 2020-06-12 서울시립대학교 산학협력단 세포전환용 rna 나노입자를 이용한 유도만능줄기세포의 제조방법
EP3969571A4 (en) 2019-05-14 2023-05-24 Aleph Farms Ltd. PLURIPOTENTE CELL AGGREGATES AND THEIR USE
CA3145425A1 (en) 2019-07-03 2021-01-07 Factor Bioscience Inc. Cationic lipids and uses thereof
US10501404B1 (en) 2019-07-30 2019-12-10 Factor Bioscience Inc. Cationic lipids and transfection methods
WO2021149822A1 (ja) * 2020-01-24 2021-07-29 アイ ピース， インコーポレイテッド 人工多能性幹細胞の作製方法
JP2022104813A (ja) 2020-12-29 2022-07-11 アイ ピース，インコーポレイテッド リプログラミング因子を導入された細胞の培養方法

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CA2872688A1 (en) 2013-11-21
HK1204005A1 (en) 2015-11-06
AU2019203335B2 (en) 2021-10-21
KR20150035594A (ko) 2015-04-06
CA2872688C (en) 2023-09-19
DK2850179T3 (da) 2019-06-17
ES2729563T3 (es) 2019-11-04
AU2019203335A1 (en) 2019-05-30
AU2013263101B2 (en) 2019-02-14
JP2015517311A (ja) 2015-06-22
EP3561054C0 (en) 2023-07-05
AU2013263101A1 (en) 2014-11-27
ES2951822T3 (es) 2023-10-25
EP2850179A4 (en) 2016-02-24
EP2850179A2 (en) 2015-03-25
CN104520424A (zh) 2015-04-15
KR20200021553A (ko) 2020-02-28
JP6530452B2 (ja) 2019-06-12
EP3561054A1 (en) 2019-10-30
EP3561054B1 (en) 2023-07-05
JP2017184766A (ja) 2017-10-12
EP2850179B1 (en) 2019-03-20
CN104520424B (zh) 2019-06-28
JP6448531B2 (ja) 2019-01-09
KR102215413B1 (ko) 2021-02-16
KR102081811B1 (ko) 2020-02-26
CN110241087A (zh) 2019-09-17
WO2013173248A2 (en) 2013-11-21

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