ES2721916T3 - Composición oral sólida que contiene colorantes para uso en diagnóstico endoscópico - Google Patents

Composición oral sólida que contiene colorantes para uso en diagnóstico endoscópico Download PDF

Info

Publication number
ES2721916T3
ES2721916T3 ES13774382T ES13774382T ES2721916T3 ES 2721916 T3 ES2721916 T3 ES 2721916T3 ES 13774382 T ES13774382 T ES 13774382T ES 13774382 T ES13774382 T ES 13774382T ES 2721916 T3 ES2721916 T3 ES 2721916T3
Authority
ES
Spain
Prior art keywords
dye
unit doses
weight
matrix
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13774382T
Other languages
English (en)
Spanish (es)
Inventor
Luigi Moro
Alessandro Repici
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cosmo Technologies Ltd
Original Assignee
Cosmo Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cosmo Technologies Ltd filed Critical Cosmo Technologies Ltd
Application granted granted Critical
Publication of ES2721916T3 publication Critical patent/ES2721916T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/006Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/003Thiazine dyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0063Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0076Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion
    • A61K49/0084Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion liposome, i.e. bilayered vesicular structure
    • A61K49/0086Polymersome, i.e. liposome with polymerisable or polymerized bilayered-forming substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0063Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0089Particulate, powder, adsorbate, bead, sphere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846Poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Optics & Photonics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES13774382T 2012-10-19 2013-09-26 Composición oral sólida que contiene colorantes para uso en diagnóstico endoscópico Active ES2721916T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261715981P 2012-10-19 2012-10-19
EP12189206.1A EP2722058A1 (en) 2012-10-19 2012-10-19 Solid oral composition containing dyes for use in endoscopic diagnosis
PCT/EP2013/070060 WO2014060199A1 (en) 2012-10-19 2013-09-26 Solid oral composition containing dyes for use in endoscopic diagnosis

Publications (1)

Publication Number Publication Date
ES2721916T3 true ES2721916T3 (es) 2019-08-06

Family

ID=47137560

Family Applications (2)

Application Number Title Priority Date Filing Date
ES13774382T Active ES2721916T3 (es) 2012-10-19 2013-09-26 Composición oral sólida que contiene colorantes para uso en diagnóstico endoscópico
ES19159230T Active ES3030697T3 (en) 2012-10-19 2013-09-26 Solid oral composition containing dyes for use in endoscopic diagnosis

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES19159230T Active ES3030697T3 (en) 2012-10-19 2013-09-26 Solid oral composition containing dyes for use in endoscopic diagnosis

Country Status (27)

Country Link
US (4) US20150283268A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (3) EP2722058A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP6267210B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR102207507B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (3) CN104755107A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR091984A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU2013331964B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR112015008772A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2886201C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (2) DK3650048T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (2) ES2721916T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI3650048T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HR (1) HRP20190710T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HUE043112T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL237907A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN2015DN02818A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LT (1) LT2908866T (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX361737B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ706363A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL2908866T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT2908866T (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RS (1) RS59152B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2649783C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TR (1) TR201905800T4 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TWI651102B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2014060199A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA201502370B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112019010691A2 (pt) * 2016-11-28 2019-10-01 Cosmo Technologies Ltd composição oral sólida contendo corantes
IT201900003113A1 (it) * 2019-03-04 2020-09-04 Azienda Ospedaliero Univ Policlinico S Orsola Malpighi Bologna Bevanda coadiuvante

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2129273C1 (ru) * 1997-11-26 1999-04-20 Московский научно-исследовательский онкологический институт им.П.А.Герцена Способ эндоскопической флюоресцентной диагностики злокачественных опухолей полых органов
EP1183014B1 (en) 1999-06-14 2003-10-08 Cosmo S.p.A. Controlled release and taste masking oral pharmaceutical compositions
ITMI991316A1 (it) 1999-06-14 2000-12-14 Cip Ninety Two 92 S A Composizioni farmaceutiche orali a rilascio modificato di mesalazina
US7230088B2 (en) * 2001-07-03 2007-06-12 Mallinckrodt, Inc. Compounds for dual photodiagnosis and therapy
GB0224909D0 (en) * 2002-10-25 2002-12-04 Norgine Europe Bv Colon cleansing compositions
RU2253350C2 (ru) * 2003-06-30 2005-06-10 Государственное учреждение здравоохранения Иркутский Областной Диагностический Центр Способ эндоскопического исследования желудка
US20050244368A1 (en) * 2004-04-29 2005-11-03 Pashankar Dinesh S Pre-endoscopic use of polyethylene glycol compositions
FR2894253B1 (fr) * 2005-12-06 2009-11-13 Pentax Corp Composition d'histocolorant pour endoscope
IT1398643B1 (it) 2010-03-04 2013-03-08 Cosmo Technologies Ltd Composizione solida per la somministrazione orale di coloranti, e utilizzo diagnostico della stessa

Also Published As

Publication number Publication date
IL237907A (en) 2017-06-29
EP2908866A1 (en) 2015-08-26
LT2908866T (lt) 2019-06-10
DK3650048T3 (da) 2025-05-26
HUE043112T2 (hu) 2019-08-28
DK2908866T3 (da) 2019-05-06
WO2014060199A1 (en) 2014-04-24
CN117462704A (zh) 2024-01-30
CN112891563A (zh) 2021-06-04
NZ706363A (en) 2019-03-29
IN2015DN02818A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2015-09-11
EP2908866B1 (en) 2019-02-27
ES3030697T3 (en) 2025-07-01
US20230130628A1 (en) 2023-04-27
PL2908866T3 (pl) 2019-10-31
US20250186626A1 (en) 2025-06-12
CA2886201C (en) 2021-03-23
US20200129643A1 (en) 2020-04-30
EP2722058A1 (en) 2014-04-23
AU2013331964B2 (en) 2018-03-29
US20150283268A1 (en) 2015-10-08
BR112015008772A2 (pt) 2017-07-04
FI3650048T3 (fi) 2025-05-26
AU2013331964A1 (en) 2015-04-09
MX2015004935A (es) 2015-12-01
JP2015534956A (ja) 2015-12-07
KR102207507B1 (ko) 2021-01-27
TWI651102B (zh) 2019-02-21
PT2908866T (pt) 2019-05-24
TW201420131A (zh) 2014-06-01
TR201905800T4 (tr) 2019-05-21
JP6267210B2 (ja) 2018-01-24
RU2649783C2 (ru) 2018-04-04
AR091984A1 (es) 2015-03-18
HK1211465A1 (en) 2016-05-27
RU2015118584A (ru) 2016-12-10
EP3650048B1 (en) 2025-03-05
EP3650048A1 (en) 2020-05-13
MX361737B (es) 2018-12-14
HRP20190710T1 (hr) 2019-08-23
RS59152B1 (sr) 2019-10-31
CA2886201A1 (en) 2014-04-24
KR20150068412A (ko) 2015-06-19
CN104755107A (zh) 2015-07-01
ZA201502370B (en) 2016-11-30

Similar Documents

Publication Publication Date Title
MX2019010354A (es) Derivado de heteroaril[4,3-c]pirimidina-5-amina, metodo de preparacion del mismo y usos medicos del mismo.
CL2013003598A1 (es) Compuestos derivados de benzooxazepinona, moduladores de canales de sodio; composición farmacéutica que los comprende; y su uso en el tratamiento de enfermedades seleccionadas de arritmias, insuficiencia cardiaca, angina, infarto al miocardio, diabetes, entre otras
GT200600445A (es) Formas de presentación farmaceuticas solidas de administración oral con liberacion rapida del principio activo.
CL2007001870A1 (es) Composicion farmaceutica de dosificacion solida que comprende valsartan, amlodipina, hidroclorotiazida y aditivos farmaceuticamente aceptables; procedimiento de preparacion; y uso para el tratamiento de hipertension, insuficiencia cardiaca, infarto d
CL2012001836A1 (es) Compuestos de pirazol, antagonista de crth2; composicion farmacéutica; uso en el tratamiento de trastornos inflamatorios, infecciosos, inmunoreguladores, enfermedades respiratorias, gastrointestinales o dolencias, entre otros.
EA201300159A8 (ru) Использование композиции salvia miltiorrhiza в приготовлении лекарственных препаратов для вторичной профилактики ишемической болезни сердца
UA106636C2 (uk) Морфолінотіазоли як позитивні алостеричні модулятори альфа 7
AR069211A1 (es) Derivados de acidos de 1,2,4-oxadiazol ciclobutanoamino carboxilicos, una composicion farmaceutica, proceso de preparacion del compuesto y su uso para preparar medicamentos
UY31294A1 (es) Derivados de tetrahidrocarbozol, métodos para obtenerlos, formulaciones que los contienen y usos de los mismos
CY1118057T1 (el) Φαρμακευτικη συνθεση για στοματικη χορηγηση
AR083361A1 (es) Forma de dosificacion de rapida disolucion de vacuna oral utilizando almidon
CR20140540A (es) Nueva forma de dosificación y formulación de abediterol
CL2008001820A1 (es) Compuestos derivados de aril-isoxasol-imidazol; procedimiento de preparacion; composicion farmaceutica que los contiene; y uso en la preparacion de medicamentos utiles en el tratamiento de trastornos cognitivos y enfermedades relacionadas con alzheimer.
EA201590797A1 (ru) Препараты с модифицированным высвобождением опрозомиба
BR112015007592A2 (pt) composições de enalapril
PE20090371A1 (es) Formulacion de nevirapina de liberacion prolongada
AR073265A1 (es) Uso de dronedarona para la preparacion de un medicamento para la prevencion de ictus o ataque isquemico transitorio
AR102778A1 (es) Composición farmacéutica, su preparación y sus usos
CO2019003808A2 (es) Composición farmacéutica que comprende antagonista receptor de mineralocorticoides y uso de la misma
ES2721916T3 (es) Composición oral sólida que contiene colorantes para uso en diagnóstico endoscópico
AR094146A1 (es) Unidad solida con alto contenido en fexofenadina y su procedimiento de preparacion
EA201691034A1 (ru) Композиции в твердой форме с замедленным высвобождением для перорального введения
PE20091900A1 (es) Una formulacion farmaceutica solida
AR080256A1 (es) Formulaciones farmaceuticas solidas de ramipril y besilato de amlodipino y su preparacion
ECSP088285A (es) 3-(2-dimetilaminometil ciclohexil) fenol formulación retardada.