ES2691401T3 - Contador de dosis y mecanismo de bloqueo - Google Patents
Contador de dosis y mecanismo de bloqueo Download PDFInfo
- Publication number
- ES2691401T3 ES2691401T3 ES09743076.3T ES09743076T ES2691401T3 ES 2691401 T3 ES2691401 T3 ES 2691401T3 ES 09743076 T ES09743076 T ES 09743076T ES 2691401 T3 ES2691401 T3 ES 2691401T3
- Authority
- ES
- Spain
- Prior art keywords
- frame
- inhaler
- spring assembly
- counter wheel
- cam
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000007246 mechanism Effects 0.000 title description 17
- 239000003814 drug Substances 0.000 claims abstract description 37
- 229940079593 drug Drugs 0.000 claims abstract description 34
- 229940071648 metered dose inhaler Drugs 0.000 claims abstract description 14
- 230000000717 retained effect Effects 0.000 claims abstract description 5
- 239000000203 mixture Substances 0.000 claims abstract description 3
- 238000009472 formulation Methods 0.000 claims abstract 2
- 230000029058 respiratory gaseous exchange Effects 0.000 claims description 5
- 230000014759 maintenance of location Effects 0.000 description 15
- 230000006870 function Effects 0.000 description 7
- 230000006835 compression Effects 0.000 description 6
- 238000007906 compression Methods 0.000 description 6
- 230000000903 blocking effect Effects 0.000 description 5
- 239000003380 propellant Substances 0.000 description 5
- 230000014509 gene expression Effects 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 239000000443 aerosol Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000006641 stabilisation Effects 0.000 description 3
- 238000011105 stabilization Methods 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 150000005828 hydrofluoroalkanes Chemical class 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 230000000284 resting effect Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 230000004913 activation Effects 0.000 description 1
- 239000000556 agonist Substances 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 229940124630 bronchodilator Drugs 0.000 description 1
- 239000000168 bronchodilator agent Substances 0.000 description 1
- KYKAJFCTULSVSH-UHFFFAOYSA-N chloro(fluoro)methane Chemical compound F[C]Cl KYKAJFCTULSVSH-UHFFFAOYSA-N 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000003246 corticosteroid Substances 0.000 description 1
- 229960001334 corticosteroids Drugs 0.000 description 1
- 230000009849 deactivation Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000002650 habitual effect Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000011236 particulate material Substances 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0081—Locking means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
- A61M15/0025—Mouthpieces therefor with caps
- A61M15/0026—Hinged caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/007—Mechanical counters
- A61M15/0071—Mechanical counters having a display or indicator
- A61M15/0076—Mechanical counters having a display or indicator on a drum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0096—Hindering inhalation before activation of the dispenser
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US126855P | 1999-03-30 | ||
| US12685508P | 2008-05-07 | 2008-05-07 | |
| PCT/US2009/002860 WO2009137089A1 (en) | 2008-05-07 | 2009-05-07 | Dose counter and lockout mechanism |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2691401T3 true ES2691401T3 (es) | 2018-11-27 |
Family
ID=41264893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09743076.3T Active ES2691401T3 (es) | 2008-05-07 | 2009-05-07 | Contador de dosis y mecanismo de bloqueo |
Country Status (13)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101566305B1 (ko) * | 2008-05-07 | 2015-11-05 | 맵 파마슈티컬스, 인코포레이티드 | 투약량 계수기 및 록아웃 메카니즘 |
| US8333729B2 (en) * | 2009-04-07 | 2012-12-18 | Polybiotics Llc | Multi-dose delivery system |
| EP2617448A1 (en) | 2012-01-20 | 2013-07-24 | Almirall S.A. | Inhalation device for powdered drugs |
| US20150306322A9 (en) * | 2012-01-23 | 2015-10-29 | Sanofi Sa | Inhalation Device |
| GB201223008D0 (en) * | 2012-12-20 | 2013-01-30 | Euro Celtique Sa | Counter |
| US10722666B2 (en) * | 2014-05-07 | 2020-07-28 | Boehringer Ingelheim International Gmbh | Nebulizer with axially movable and lockable container and indicator |
| GB201610450D0 (en) * | 2016-06-15 | 2016-07-27 | Tech Partnership The Plc | Counting mechanism |
| CN106039497A (zh) * | 2016-08-08 | 2016-10-26 | 中山市美捷时包装制品有限公司 | 一种干粉吸入装置的计数机构 |
| US11369760B2 (en) * | 2016-08-24 | 2022-06-28 | Anovent Pharmaceutical (U.S.), Llc | Inhalation atomizer comprising a blocking function and a counter |
| GB201615186D0 (en) * | 2016-09-07 | 2016-10-19 | 3M Innovative Properties Co | Energy storage mechanism for an inhaler |
| GB201706504D0 (en) * | 2017-04-25 | 2017-06-07 | 3M Innovative Properties Co | Medicinal inhaler comprising a lockout override mechanism |
| KR102581577B1 (ko) * | 2018-09-27 | 2023-09-25 | 에스에이치엘 메디컬 아게 | 에어로졸 디스펜서용 투여량 카운팅 메커니즘 |
| CN109091734A (zh) * | 2018-10-30 | 2018-12-28 | 徐州医科大学 | 一种吸气触发的且具计数功能的气雾剂吸入装置 |
| WO2021009022A1 (en) * | 2019-07-12 | 2021-01-21 | Sanofi | Fluid dispensing device |
| US11883582B2 (en) * | 2019-10-17 | 2024-01-30 | Astrazeneca Ab | Inhaler |
| CA195581S (en) * | 2019-11-18 | 2022-03-11 | Vectura Delivery Devices Ltd | Monitor for an inhaler |
| CN212491038U (zh) * | 2020-03-18 | 2021-02-09 | 苏州天健云康信息科技有限公司 | 液体给药装置 |
| USD1063061S1 (en) * | 2022-03-17 | 2025-02-18 | Adherium (Nz) Limited | Inhaler usage monitor |
| GB2637900A (en) * | 2023-10-30 | 2025-08-13 | Merxin Ltd | End-of-life lockout mechanisms for inhalers |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5119806A (en) | 1987-05-12 | 1992-06-09 | Glaxo Inc. | Inhalation device |
| GB8919131D0 (en) * | 1989-08-23 | 1989-10-04 | Riker Laboratories Inc | Inhaler |
| GB9024760D0 (en) * | 1990-11-14 | 1991-01-02 | Riker Laboratories Inc | Inhalation device and medicament carrier |
| GB9217545D0 (en) | 1992-08-18 | 1992-09-30 | Minnesota Mining & Mfg | Inhalation device |
| FR2721106B1 (fr) * | 1994-06-10 | 1996-09-13 | Step | Compteur de doses pour inhalateurs. |
| US6672304B1 (en) * | 1995-06-08 | 2004-01-06 | Innovative Devices, Llc | Inhalation actuated device for use with metered dose inhalers (MDIs) |
| DE29814647U1 (de) * | 1998-08-14 | 1999-12-23 | Josef Wischerath Gmbh & Co. Kg, 50259 Pulheim | Inhalator mit einer Dosierzähleinrichtung |
| US6615827B2 (en) | 1999-09-08 | 2003-09-09 | Sapphire Designs, Inc. | Inhalation counter device |
| FR2799858B1 (fr) * | 1999-10-19 | 2002-01-18 | Valois Sa | Compteur de doses et distributeur de produit fluide incorporant un tel compteur |
| PT1229953E (pt) | 1999-11-10 | 2007-02-28 | Innovative Devices Llc | Dispositivo accionado por inalaçao para ser utilizado com inaladores doseadores (mdi) |
| TWI224513B (en) * | 2000-06-23 | 2004-12-01 | Norton Healthcare Ltd | Dose counter for medicament inhaler |
| EP1558317A2 (en) | 2002-11-04 | 2005-08-03 | Cambridge Consultants Limited | Pressurised inhalers |
| GB2398254B (en) | 2003-02-11 | 2005-12-07 | Bespak Plc | Dispensing Apparatus |
| US7621273B2 (en) | 2003-10-28 | 2009-11-24 | Trudell Medical International | Indicating device with warning dosage indicator |
| US8113199B2 (en) | 2004-02-16 | 2012-02-14 | Glaxo Group Limited | Counter for use with a medicament dispenser |
| EP1616592B9 (en) * | 2004-07-16 | 2011-02-02 | Almirall, S.A. | Inhaler for the administration of powdered pharmaceuticals, and a powder cartridge for use with this inhaler |
| KR20080042085A (ko) | 2005-08-24 | 2008-05-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 분무기 |
| US8479732B2 (en) * | 2006-04-21 | 2013-07-09 | 3M Innovative Properties Company | Dose counter |
| KR101566305B1 (ko) * | 2008-05-07 | 2015-11-05 | 맵 파마슈티컬스, 인코포레이티드 | 투약량 계수기 및 록아웃 메카니즘 |
-
2009
- 2009-05-07 KR KR1020107027441A patent/KR101566305B1/ko not_active Expired - Fee Related
- 2009-05-07 JP JP2011508514A patent/JP5681622B2/ja not_active Expired - Fee Related
- 2009-05-07 ES ES09743076.3T patent/ES2691401T3/es active Active
- 2009-05-07 AU AU2009244808A patent/AU2009244808B2/en not_active Ceased
- 2009-05-07 MX MX2010012043A patent/MX2010012043A/es active IP Right Grant
- 2009-05-07 CN CN200980116429.4A patent/CN102065940B/zh not_active Expired - Fee Related
- 2009-05-07 TR TR2018/15014T patent/TR201815014T4/tr unknown
- 2009-05-07 EP EP09743076.3A patent/EP2288401B1/en active Active
- 2009-05-07 US US12/387,867 patent/US8720433B2/en not_active Expired - Fee Related
- 2009-05-07 DK DK09743076.3T patent/DK2288401T3/en active
- 2009-05-07 WO PCT/US2009/002860 patent/WO2009137089A1/en not_active Ceased
- 2009-05-07 CA CA2723354A patent/CA2723354C/en active Active
-
2010
- 2010-10-24 IL IL208894A patent/IL208894A/en active IP Right Grant
-
2013
- 2013-09-02 JP JP2013180971A patent/JP2013236966A/ja active Pending
-
2014
- 2014-01-15 US US14/155,581 patent/US9480803B2/en active Active
-
2016
- 2016-09-22 US US15/272,597 patent/US20170007786A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009137089A1 (en) | 2009-11-12 |
| US20110017210A1 (en) | 2011-01-27 |
| MX2010012043A (es) | 2010-12-06 |
| EP2288401A1 (en) | 2011-03-02 |
| AU2009244808A1 (en) | 2009-11-12 |
| IL208894A (en) | 2013-08-29 |
| US20140123975A1 (en) | 2014-05-08 |
| CA2723354C (en) | 2015-03-31 |
| JP2011519667A (ja) | 2011-07-14 |
| EP2288401A4 (en) | 2015-01-07 |
| CA2723354A1 (en) | 2009-11-12 |
| KR101566305B1 (ko) | 2015-11-05 |
| EP2288401B1 (en) | 2018-07-11 |
| IL208894A0 (en) | 2011-01-31 |
| US9480803B2 (en) | 2016-11-01 |
| DK2288401T3 (en) | 2018-10-29 |
| JP5681622B2 (ja) | 2015-03-11 |
| TR201815014T4 (tr) | 2018-11-21 |
| KR20110013454A (ko) | 2011-02-09 |
| US8720433B2 (en) | 2014-05-13 |
| CN102065940B (zh) | 2014-06-11 |
| JP2013236966A (ja) | 2013-11-28 |
| CN102065940A (zh) | 2011-05-18 |
| US20170007786A1 (en) | 2017-01-12 |
| AU2009244808B2 (en) | 2014-06-05 |
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