ES2647597T3 - Combinación de adrenalina con un antidepresivo para utilizar en el tratamiento de choques - Google Patents
Combinación de adrenalina con un antidepresivo para utilizar en el tratamiento de choques Download PDFInfo
- Publication number
- ES2647597T3 ES2647597T3 ES13771500.9T ES13771500T ES2647597T3 ES 2647597 T3 ES2647597 T3 ES 2647597T3 ES 13771500 T ES13771500 T ES 13771500T ES 2647597 T3 ES2647597 T3 ES 2647597T3
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- adrenaline
- antidepressant
- solution
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- shock
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- 230000002045 lasting effect Effects 0.000 description 1
- 239000003446 ligand Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000011866 long-term treatment Methods 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 230000010016 myocardial function Effects 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 239000002858 neurotransmitter agent Substances 0.000 description 1
- 230000012154 norepinephrine uptake Effects 0.000 description 1
- 229940005483 opioid analgesics Drugs 0.000 description 1
- 150000007530 organic bases Chemical class 0.000 description 1
- 229940092253 ovalbumin Drugs 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 230000001991 pathophysiological effect Effects 0.000 description 1
- 150000002960 penicillins Chemical class 0.000 description 1
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical compound OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 description 1
- 230000036470 plasma concentration Effects 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 229940071643 prefilled syringe Drugs 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002315 pressor effect Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000036303 septic shock Effects 0.000 description 1
- 229940076279 serotonin Drugs 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 230000016160 smooth muscle contraction Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229940001607 sodium bisulfite Drugs 0.000 description 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 230000006794 tachycardia Effects 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 230000006442 vascular tone Effects 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12306207 | 2012-10-03 | ||
| EP12306207 | 2012-10-03 | ||
| PCT/EP2013/070598 WO2014053579A1 (en) | 2012-10-03 | 2013-10-02 | A combination of adrenalin with an antidepressant for use in the treatment of shocks |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2647597T3 true ES2647597T3 (es) | 2017-12-22 |
Family
ID=47073380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES13771500.9T Active ES2647597T3 (es) | 2012-10-03 | 2013-10-02 | Combinación de adrenalina con un antidepresivo para utilizar en el tratamiento de choques |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US20150306065A1 (enExample) |
| EP (1) | EP2903607B1 (enExample) |
| JP (1) | JP6419074B2 (enExample) |
| KR (1) | KR102145786B1 (enExample) |
| CN (1) | CN104780916B (enExample) |
| AU (1) | AU2013326470B2 (enExample) |
| BR (1) | BR112015007524B1 (enExample) |
| CA (1) | CA2887330C (enExample) |
| CY (1) | CY1119514T1 (enExample) |
| DK (1) | DK2903607T3 (enExample) |
| EA (1) | EA030763B1 (enExample) |
| ES (1) | ES2647597T3 (enExample) |
| HR (1) | HRP20171442T1 (enExample) |
| HU (1) | HUE034638T2 (enExample) |
| IL (1) | IL238120B (enExample) |
| IN (1) | IN2015DN02849A (enExample) |
| LT (1) | LT2903607T (enExample) |
| MA (1) | MA37970B2 (enExample) |
| MX (1) | MX359198B (enExample) |
| NO (1) | NO2903607T3 (enExample) |
| NZ (1) | NZ707124A (enExample) |
| PH (1) | PH12015500755A1 (enExample) |
| PL (1) | PL2903607T3 (enExample) |
| PT (1) | PT2903607T (enExample) |
| RS (1) | RS56392B1 (enExample) |
| SG (1) | SG11201502645VA (enExample) |
| SI (1) | SI2903607T1 (enExample) |
| SM (1) | SMT201700502T1 (enExample) |
| TN (1) | TN2015000126A1 (enExample) |
| WO (1) | WO2014053579A1 (enExample) |
| ZA (1) | ZA201502441B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4706648A1 (en) | 2024-09-05 | 2026-03-11 | Bioprojet | Formulations of adrenalin and antidepressant |
| EP4706649A1 (en) | 2024-09-05 | 2026-03-11 | Bioprojet | Use of adrenalin for the treatment of shocks |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3705942A (en) * | 1969-09-29 | 1972-12-12 | Ciba Geigy Corp | Treatment of glaucoma employing imipramine or desmethylimipramine |
| TW200744568A (en) * | 2006-02-28 | 2007-12-16 | Verus Pharmaceuticals Inc | Epinephrine dosing regimens |
| US20070293582A1 (en) * | 2006-06-05 | 2007-12-20 | Malcolm Hill | Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms |
| PT2818184T (pt) * | 2007-11-16 | 2019-01-28 | Aclaris Therapeutics Inc | Composições e métodos para o tratamento de púrpura |
| SE533552C2 (sv) * | 2008-12-30 | 2010-10-26 | Igeloesa Transplantation Science Ab | Förfarande och lösning för behandling av en potentiell organdonator |
| US20100190860A1 (en) * | 2009-01-09 | 2010-07-29 | The Brigham And Women's Hospital, Inc. | Methods for selectively enhancing antinociceptive potency of local anesthetics |
| CN101987198B (zh) * | 2009-08-06 | 2014-08-13 | 北京美倍他药物研究有限公司 | 药物组合物 |
-
2013
- 2013-10-02 PL PL13771500T patent/PL2903607T3/pl unknown
- 2013-10-02 IN IN2849DEN2015 patent/IN2015DN02849A/en unknown
- 2013-10-02 JP JP2015535014A patent/JP6419074B2/ja active Active
- 2013-10-02 HU HUE13771500A patent/HUE034638T2/en unknown
- 2013-10-02 MA MA37970A patent/MA37970B2/fr unknown
- 2013-10-02 EA EA201500374A patent/EA030763B1/ru not_active IP Right Cessation
- 2013-10-02 PT PT137715009T patent/PT2903607T/pt unknown
- 2013-10-02 BR BR112015007524-0A patent/BR112015007524B1/pt active IP Right Grant
- 2013-10-02 RS RS20170973A patent/RS56392B1/sr unknown
- 2013-10-02 CN CN201380057617.0A patent/CN104780916B/zh active Active
- 2013-10-02 SG SG11201502645VA patent/SG11201502645VA/en unknown
- 2013-10-02 KR KR1020157010740A patent/KR102145786B1/ko active Active
- 2013-10-02 US US14/433,549 patent/US20150306065A1/en not_active Abandoned
- 2013-10-02 SM SM20170502T patent/SMT201700502T1/it unknown
- 2013-10-02 AU AU2013326470A patent/AU2013326470B2/en active Active
- 2013-10-02 WO PCT/EP2013/070598 patent/WO2014053579A1/en not_active Ceased
- 2013-10-02 EP EP13771500.9A patent/EP2903607B1/en active Active
- 2013-10-02 NO NO13771500A patent/NO2903607T3/no unknown
- 2013-10-02 DK DK13771500.9T patent/DK2903607T3/en active
- 2013-10-02 HR HRP20171442TT patent/HRP20171442T1/hr unknown
- 2013-10-02 CA CA2887330A patent/CA2887330C/en active Active
- 2013-10-02 SI SI201330817T patent/SI2903607T1/sl unknown
- 2013-10-02 MX MX2015004323A patent/MX359198B/es active IP Right Grant
- 2013-10-02 NZ NZ707124A patent/NZ707124A/en unknown
- 2013-10-02 ES ES13771500.9T patent/ES2647597T3/es active Active
- 2013-10-02 LT LTEP13771500.9T patent/LT2903607T/lt unknown
-
2015
- 2015-04-02 TN TNP2015000126A patent/TN2015000126A1/fr unknown
- 2015-04-02 IL IL238120A patent/IL238120B/en active IP Right Grant
- 2015-04-06 PH PH12015500755A patent/PH12015500755A1/en unknown
- 2015-04-10 ZA ZA2015/02441A patent/ZA201502441B/en unknown
-
2017
- 2017-10-31 CY CY20171101135T patent/CY1119514T1/el unknown
-
2018
- 2018-12-18 US US16/223,750 patent/US10952987B2/en active Active
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