ES2641862T3 - Proceso para la elaboración de inhibidores de CCR3 - Google Patents

Proceso para la elaboración de inhibidores de CCR3 Download PDF

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Publication number
ES2641862T3
ES2641862T3 ES13712567.0T ES13712567T ES2641862T3 ES 2641862 T3 ES2641862 T3 ES 2641862T3 ES 13712567 T ES13712567 T ES 13712567T ES 2641862 T3 ES2641862 T3 ES 2641862T3
Authority
ES
Spain
Prior art keywords
elaboration
ccr3 inhibitors
ccr3
inhibitors
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13712567.0T
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English (en)
Spanish (es)
Inventor
Adil Duran
Rolf Schmid
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alkahest Inc
Original Assignee
Alkahest Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkahest Inc filed Critical Alkahest Inc
Application granted granted Critical
Publication of ES2641862T3 publication Critical patent/ES2641862T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
ES13712567.0T 2012-04-02 2013-03-28 Proceso para la elaboración de inhibidores de CCR3 Active ES2641862T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12162852 2012-04-02
EP12162852 2012-04-02
PCT/EP2013/056638 WO2013149926A1 (en) 2012-04-02 2013-03-28 Process for the manufacturing of ccr3 inhibitors

Publications (1)

Publication Number Publication Date
ES2641862T3 true ES2641862T3 (es) 2017-11-14

Family

ID=47998462

Family Applications (1)

Application Number Title Priority Date Filing Date
ES13712567.0T Active ES2641862T3 (es) 2012-04-02 2013-03-28 Proceso para la elaboración de inhibidores de CCR3

Country Status (9)

Country Link
US (1) US8680280B2 (enExample)
EP (1) EP2834229B1 (enExample)
JP (1) JP6255550B2 (enExample)
AR (1) AR090566A1 (enExample)
DK (1) DK2834229T3 (enExample)
ES (1) ES2641862T3 (enExample)
TW (1) TW201400474A (enExample)
UY (1) UY34719A (enExample)
WO (1) WO2013149926A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8278302B2 (en) 2009-04-08 2012-10-02 Boehringer Ingelheim International Gmbh Substituted piperidines as CCR3 antagonists
UA109290C2 (uk) 2010-10-07 2015-08-10 Спільні кристали і солі інгібіторів ccr3
AR090566A1 (es) 2012-04-02 2014-11-19 Boehringer Ingelheim Int Proceso para la produccion de inhibidores de crr
US10213421B2 (en) 2012-04-04 2019-02-26 Alkahest, Inc. Pharmaceutical formulations comprising CCR3 antagonists
NZ757769A (en) 2017-04-05 2025-10-31 Alkahest Inc Methods and compositions for treating retina-associated disease using ccr3-inhibitors
WO2018187503A1 (en) 2017-04-05 2018-10-11 Alkahest, Inc. Methods and compositions for treating aging-associated impairments using ccr3-inhibitors
AU2019271122A1 (en) 2018-05-15 2020-11-12 Alkahest, Inc. Treatment of aging-associated disease with modulators of leukotriene A4 hydrolase
US11957671B2 (en) 2021-11-01 2024-04-16 Alkahest, Inc. Benzodioxane modulators of leukotriene A4 hydrolase (LTA4H) for prevention and treatment of aging-associated diseases

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7907121L (sv) 1979-08-27 1981-02-28 Astra Laekemedel Ab Ftalimidinderivat
JP2807577B2 (ja) 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
JPH08134041A (ja) * 1994-11-10 1996-05-28 Fuji Photo Film Co Ltd ピラゾールアミド類の製造方法
EP1047675A1 (en) 1998-01-21 2000-11-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US6140349A (en) 1998-02-02 2000-10-31 Merck & Co., Inc. Cyclic amine modulators of chemokine receptor activity
JP2002501898A (ja) 1998-02-02 2002-01-22 メルク エンド カムパニー インコーポレーテッド ケモカイン受容体活性の環状アミン調節剤
ES2324224T3 (es) 2004-02-05 2009-08-03 Schering Corporation Derivados de piperidina que se pueden utilizar como antagonistas ccr3.
JP2006137718A (ja) 2004-11-12 2006-06-01 Astellas Pharma Inc インドール若しくはインダゾール誘導体
WO2006083390A2 (en) 2004-12-07 2006-08-10 Children's Hospital Medical Center Eotaxin-3 in eosinophilic esophagitis
DOP2006000051A (es) * 2005-02-24 2006-08-31 Lilly Co Eli Inhibidores de vegf-r2 y métodos
EP2059515A2 (en) 2006-04-12 2009-05-20 Pfizer Limited Pyrrolidine derivatives as modulators of chemokine ccr5 receptors
GB0701992D0 (en) 2007-02-02 2007-03-14 7Tm Pharma As Grehlin Receptor Modulators
US8008092B2 (en) 2007-10-09 2011-08-30 University Of Kentucky Research Foundation CCR3 inhibition for ocular angiogenesis and macular degeneration
TW201000446A (en) 2008-05-30 2010-01-01 Astrazeneca Ab New compounds useful in pain therapy
US8278302B2 (en) 2009-04-08 2012-10-02 Boehringer Ingelheim International Gmbh Substituted piperidines as CCR3 antagonists
UA109290C2 (uk) 2010-10-07 2015-08-10 Спільні кристали і солі інгібіторів ccr3
AR090566A1 (es) 2012-04-02 2014-11-19 Boehringer Ingelheim Int Proceso para la produccion de inhibidores de crr
US20130261153A1 (en) 2012-04-03 2013-10-03 Boehringer Ingelheim International Gmbh Use of ccr3-inhibitors
US10213421B2 (en) 2012-04-04 2019-02-26 Alkahest, Inc. Pharmaceutical formulations comprising CCR3 antagonists

Also Published As

Publication number Publication date
US20130261307A1 (en) 2013-10-03
DK2834229T3 (da) 2017-11-20
UY34719A (es) 2013-10-31
EP2834229B1 (en) 2017-08-09
TW201400474A (zh) 2014-01-01
AR090566A1 (es) 2014-11-19
EP2834229A1 (en) 2015-02-11
WO2013149926A1 (en) 2013-10-10
US8680280B2 (en) 2014-03-25
JP6255550B2 (ja) 2018-01-10
JP2015516959A (ja) 2015-06-18

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