ES2621280T3 - Material de implantación que comprende un polímero biocompatible - Google Patents

Material de implantación que comprende un polímero biocompatible Download PDF

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Publication number
ES2621280T3
ES2621280T3 ES13161184.0T ES13161184T ES2621280T3 ES 2621280 T3 ES2621280 T3 ES 2621280T3 ES 13161184 T ES13161184 T ES 13161184T ES 2621280 T3 ES2621280 T3 ES 2621280T3
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ES
Spain
Prior art keywords
poly
ethylene oxide
hyaluronic acid
copolymer
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13161184.0T
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English (en)
Inventor
Young Woo Lee
Wan Jin Cho
Ji Yeon Jang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GENEWEL CO Ltd
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GENEWEL CO Ltd
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Publication date
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Publication of ES2621280T3 publication Critical patent/ES2621280T3/es
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
    • C08J5/18—Manufacture of films or sheets
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L101/00—Compositions of unspecified macromolecular compounds
    • C08L101/02—Compositions of unspecified macromolecular compounds characterised by the presence of specified groups, e.g. terminal or pendant functional groups

Abstract

Una película de derivado de epóxido de ácido hialurónico que comprende 50-90 % en peso de ácido hialurónico y 10-50 % en peso de un polímero que contiene un grupo terminal hidroxilo (-OH), en la que dicho polímero se une físicamente a un derivado de epóxido de ácido hialurónico reticulado, y es uno o más seleccionado del grupo que consiste en poli(óxido de etileno), poli(óxido de propileno), un copolímero de poli(óxido de etileno)-poli(óxido de propileno), un copolímero de poli(óxido de etileno)-ácido poliláctico, un copolímero de poli(óxido de etileno)-ácido poliláctico-glicólico, un copolímero de poli(óxido de etileno)-policaprolactona, poli(óxido de butileno), polioxietilen alquil éteres, derivados de aceite de ricino con polioxietileno, ésteres de ácidos grasos de sorbitano con polioxietileno, y poli(estearatos de etileno), y en la que el derivado de ácido hialurónico se prepara permitiendo que un reticulante de epóxido reaccione con ácido hialurónico o hialuronato solo o en combinación con un polímero capaz de formar un enlace covalente de éter con ácido hialurónico.

Description

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Claims (1)

  1. imagen1
ES13161184.0T 2012-03-26 2013-03-26 Material de implantación que comprende un polímero biocompatible Active ES2621280T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20120030540 2012-03-26
KR1020120030540A KR101240518B1 (ko) 2012-03-26 2012-03-26 생체 적합성 고분자를 이용한 이식용 재료

Publications (1)

Publication Number Publication Date
ES2621280T3 true ES2621280T3 (es) 2017-07-03

Family

ID=47913323

Family Applications (1)

Application Number Title Priority Date Filing Date
ES13161184.0T Active ES2621280T3 (es) 2012-03-26 2013-03-26 Material de implantación que comprende un polímero biocompatible

Country Status (6)

Country Link
US (1) US8822551B2 (es)
EP (1) EP2644623B1 (es)
JP (1) JP5934132B2 (es)
KR (1) KR101240518B1 (es)
CN (1) CN103360633B (es)
ES (1) ES2621280T3 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101649792B1 (ko) * 2014-07-16 2016-08-22 주식회사 제네웰 비압박 지혈용 고분자 폼 제조용 조성물, 이를 이용한 비압박 지혈용 고분자 폼의 제조방법 및 비압박 지혈 팩킹용 고분자 폼
CZ309295B6 (cs) 2015-03-09 2022-08-10 Contipro A.S. Samonosný, biodegradabilní film na bázi hydrofobizované kyseliny hyaluronové, způsob jeho přípravy a použití
RU2629841C1 (ru) * 2016-07-26 2017-09-04 Общество с ограниченной ответственностью "Линтекс" Способ получения противоспаечного пленочного материала на основе карбоксиметилцеллюлозы
KR20180027126A (ko) 2016-09-06 2018-03-14 (주)한국비엠아이 가교화 히알루론산 유도체 매트릭스가 포함된 지혈 조성물
CN107880282B (zh) * 2016-12-29 2020-09-29 北京键凯科技股份有限公司 一种注射用多元甘醇环氧衍生物交联的透明质酸钠凝胶及其制备方法
WO2018164358A1 (ko) 2017-03-07 2018-09-13 (주)진우바이오 히알루론산염 필름의 제조방법 및 이로부터 제조된 히알루론산염 필름
WO2019001472A1 (zh) * 2017-06-28 2019-01-03 北京键凯科技股份有限公司 分枝型多元甘醇环氧衍生物交联透明质酸钠凝胶及其制备和应用
CN109010912B (zh) * 2018-09-27 2021-05-25 福建拓烯新材料科技有限公司 一种改性的玻尿酸可注射填充材料及其制备方法
KR102093660B1 (ko) * 2019-07-08 2020-03-26 (주)리젠바이오참 온도감응형 조직유착 방지용 하이드로겔 조성물 및 그 제조방법
CN112472672B (zh) * 2020-11-30 2022-01-25 西安交通大学 一种多肽-多糖接枝共聚物基铂类纳米前药及制备方法和应用
CN115838478B (zh) * 2022-01-14 2023-09-05 天津键凯科技有限公司 一种透明质酸衍生物或其盐及其制备方法和应用

Family Cites Families (17)

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US4500676A (en) 1983-12-15 1985-02-19 Biomatrix, Inc. Hyaluronate modified polymeric articles
US4716224A (en) 1984-05-04 1987-12-29 Seikagaku Kogyo Co. Ltd. Crosslinked hyaluronic acid and its use
SE442820B (sv) 1984-06-08 1986-02-03 Pharmacia Ab Gel av tverbunden hyaluronsyra for anvendning som glaskroppssubstitut
SE456346B (sv) 1984-07-23 1988-09-26 Pharmacia Ab Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning
US4713448A (en) 1985-03-12 1987-12-15 Biomatrix, Inc. Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues
SE452469B (sv) 1986-06-18 1987-11-30 Pharmacia Ab Material bestaende av en tverbunden karboxylgrupphaltig polysackarid och forfarande vid framstellning av detsamma
JP3404557B2 (ja) * 1993-09-30 2003-05-12 グンゼ株式会社 架橋ヒアルロン酸及びこれらの複合材料
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KR20090012439A (ko) 2007-07-30 2009-02-04 주식회사 핸슨바이오텍 기관 유착 방지 특성을 갖는 히알루론산 및카르복시메칠셀룰로즈 복합체 유도체 필름 및 겔 및 그제조방법
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Also Published As

Publication number Publication date
US8822551B2 (en) 2014-09-02
JP5934132B2 (ja) 2016-06-15
CN103360633A (zh) 2013-10-23
EP2644623B1 (en) 2017-03-08
EP2644623A1 (en) 2013-10-02
KR101240518B1 (ko) 2013-03-11
US20130253074A1 (en) 2013-09-26
CN103360633B (zh) 2015-07-22
JP2013198737A (ja) 2013-10-03

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