ES2619938T3 - Quimeras de fibronectina: factor de crecimiento - Google Patents

Quimeras de fibronectina: factor de crecimiento Download PDF

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Publication number
ES2619938T3
ES2619938T3 ES10832439.3T ES10832439T ES2619938T3 ES 2619938 T3 ES2619938 T3 ES 2619938T3 ES 10832439 T ES10832439 T ES 10832439T ES 2619938 T3 ES2619938 T3 ES 2619938T3
Authority
ES
Spain
Prior art keywords
growth factor
seq
igf
protein complex
isolated protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10832439.3T
Other languages
English (en)
Spanish (es)
Inventor
Zee Upton
Derek Van Lonkhuyzen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Invert Graphite Ltd
Original Assignee
Factor Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/627,647 external-priority patent/US20100143442A1/en
Priority claimed from US12/793,386 external-priority patent/US8871709B2/en
Application filed by Factor Therapeutics Ltd filed Critical Factor Therapeutics Ltd
Application granted granted Critical
Publication of ES2619938T3 publication Critical patent/ES2619938T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
ES10832439.3T 2009-11-30 2010-11-30 Quimeras de fibronectina: factor de crecimiento Active ES2619938T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12/627,647 US20100143442A1 (en) 2003-02-05 2009-11-30 Growth factor complexes and modulation of cell migration and growth
US627647 2009-11-30
US12/793,386 US8871709B2 (en) 2003-02-05 2010-06-03 Synthetic chimeric proteins comprising epidermal growth factor and vitronectin
US793386 2010-06-03
PCT/AU2010/001613 WO2011063477A1 (en) 2009-11-30 2010-11-30 Fibronectin: growth factor chimeras

Publications (1)

Publication Number Publication Date
ES2619938T3 true ES2619938T3 (es) 2017-06-27

Family

ID=44065756

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10832439.3T Active ES2619938T3 (es) 2009-11-30 2010-11-30 Quimeras de fibronectina: factor de crecimiento

Country Status (12)

Country Link
EP (1) EP2507261B1 (cg-RX-API-DMAC10.html)
JP (1) JP2013511960A (cg-RX-API-DMAC10.html)
KR (1) KR101930916B1 (cg-RX-API-DMAC10.html)
CN (1) CN102725308A (cg-RX-API-DMAC10.html)
AU (1) AU2010324554B2 (cg-RX-API-DMAC10.html)
BR (1) BR112012013035A8 (cg-RX-API-DMAC10.html)
CA (1) CA2781474C (cg-RX-API-DMAC10.html)
ES (1) ES2619938T3 (cg-RX-API-DMAC10.html)
NZ (1) NZ600454A (cg-RX-API-DMAC10.html)
RU (1) RU2012127364A (cg-RX-API-DMAC10.html)
WO (1) WO2011063477A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201203915B (cg-RX-API-DMAC10.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8871709B2 (en) 2003-02-05 2014-10-28 Queensland University of Technolgy Synthetic chimeric proteins comprising epidermal growth factor and vitronectin
CN103834664B (zh) * 2014-03-27 2016-05-04 吉林大学 重组表皮生长因子egf及其制备方法
CN110023325B (zh) * 2016-10-14 2023-07-04 尼优美特里克斯医疗有限公司 具有提高的生物活性和降低的对嗜中性粒细胞弹性蛋白酶降解易感性的来源于纤连蛋白的肽
WO2019010533A1 (en) * 2017-07-12 2019-01-17 Factor Therapeutics Limited TREATMENT OF OCULAR DISORDERS
CN110123732A (zh) * 2019-04-03 2019-08-16 广州市拉凯尔干细胞研究所 一种含有纤连蛋白化妆品原料制备方法
CN114040923B (zh) * 2019-04-05 2024-11-26 韩国窑业技术院 利用肌集钙蛋白标签的蛋白质的表达及纯化方法
KR102440312B1 (ko) * 2020-08-28 2022-09-05 한국해양과학기술원 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도
CN119264240B (zh) * 2024-09-10 2025-03-25 浙江诸暨聚源生物技术有限公司 功能增强的重组纤连蛋白及其制备方法和应用

Family Cites Families (29)

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US4843000A (en) 1979-12-26 1989-06-27 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4849338A (en) 1982-07-16 1989-07-18 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5091513A (en) 1987-05-21 1992-02-25 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
JP3178714B2 (ja) 1988-07-15 2001-06-25 セントラル・シドニー・エリア・ヘルス・サービス インスリン様成長因子(igf)結合蛋白複合体の酸不安定サブユニット(als)
US6090790A (en) 1989-12-14 2000-07-18 Eriksson; Elof Gene delivery by microneedle injection
JP2866134B2 (ja) * 1990-02-05 1999-03-08 寳酒造株式会社 機能性ポリペプチド
AU649066B2 (en) 1990-07-25 1994-05-12 Syngene, Inc. Circular extension for generating multiple nucleic acid complements
US6054122A (en) 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
JP2829405B2 (ja) * 1991-10-14 1998-11-25 寳酒造株式会社 機能性ポリペプチド
US5958764A (en) 1992-04-30 1999-09-28 Baylor College Of Medicine Specific expression vectors and methods of use
WO1994018232A1 (en) 1993-02-12 1994-08-18 Repligen Corporation Methods for generating broadly neutralizing anti-hiv antibodies and antigens capable of eliciting same
US5422252A (en) 1993-06-04 1995-06-06 Becton, Dickinson And Company Simultaneous amplification of multiple targets
US5962427A (en) 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
AUPM672594A0 (en) 1994-07-08 1994-08-04 Royal Children's Hospital Research Foundation A method for the prophylaxis and/or treatment of proliferative and/or inflammatory skin disorders
ATE195555T1 (de) * 1994-11-29 2000-09-15 Takara Shuzo Co Verfahren zur herstellung transformierter zellen
AU709831B2 (en) * 1995-11-13 1999-09-09 Takara Bio Inc. Method for gene transfer into target cells with retrovirus
DK0862656T3 (da) 1995-11-21 2001-04-09 Univ Yale Unimolekylær segmentamplifikation og -detektering
US5752019A (en) 1995-12-22 1998-05-12 International Business Machines Corporation System and method for confirmationally-flexible molecular identification
US5835382A (en) 1996-04-26 1998-11-10 The Scripps Research Institute Small molecule mimetics of erythropoietin
US6077987A (en) 1997-09-04 2000-06-20 North Shore-Long Island Jewish Research Institute Genetic engineering of cells to enhance healing and tissue regeneration
WO1999047070A1 (en) 1998-03-18 1999-09-23 Wake Forest University Improved implantable biomaterials, compositions and methods for their preparation and uses thereof
AUPP298498A0 (en) 1998-04-17 1998-05-07 Gropep Pty Ltd Matrix binding factor
US6436897B2 (en) 1998-06-01 2002-08-20 Celtrix Pharmaceuticals, Inc. Pharmaceutical formulations for IGF/IGFBP
AU3897200A (en) 1999-03-18 2000-10-04 Hope Heart Institute, The Endothelial cell stimulation by a complex of fibronectin and vascular endothelial growth factor
AU2003900481A0 (en) * 2003-02-05 2003-02-20 Queensland University Of Technology Synthetic modulators of cell migration and growth
JP2008125460A (ja) * 2006-11-22 2008-06-05 Institute Of Physical & Chemical Research フィブリン結合性成長因子
CA2690734A1 (en) * 2007-06-14 2008-12-24 Richard A. Clark Polypeptides and methods of use

Also Published As

Publication number Publication date
NZ600454A (en) 2014-10-31
AU2010324554A1 (en) 2012-06-21
EP2507261B1 (en) 2016-12-21
EP2507261A1 (en) 2012-10-10
CA2781474C (en) 2019-06-18
JP2013511960A (ja) 2013-04-11
RU2012127364A (ru) 2014-01-10
KR101930916B1 (ko) 2018-12-19
EP2507261A4 (en) 2013-04-10
CA2781474A1 (en) 2011-06-03
KR20120114277A (ko) 2012-10-16
BR112012013035A8 (pt) 2018-04-03
WO2011063477A1 (en) 2011-06-03
BR112012013035A2 (pt) 2017-05-16
AU2010324554B2 (en) 2014-07-31
ZA201203915B (en) 2018-11-28
CN102725308A (zh) 2012-10-10

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