ES2606627T3 - Anticuerpos específicos anti-CD160 para el tratamiento de trastornos oculares basados en la neoangiogénesis - Google Patents
Anticuerpos específicos anti-CD160 para el tratamiento de trastornos oculares basados en la neoangiogénesis Download PDFInfo
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- ES2606627T3 ES2606627T3 ES11728594.0T ES11728594T ES2606627T3 ES 2606627 T3 ES2606627 T3 ES 2606627T3 ES 11728594 T ES11728594 T ES 11728594T ES 2606627 T3 ES2606627 T3 ES 2606627T3
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A61K2039/507—Comprising a combination of two or more separate antibodies
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US34927110P | 2010-05-28 | 2010-05-28 | |
| US349271P | 2010-05-28 | ||
| PCT/EP2011/058777 WO2011147984A1 (en) | 2010-05-28 | 2011-05-27 | Anti-cd160 specific antibodies for the treatment of eye disorders based on neoangiogenesis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2606627T3 true ES2606627T3 (es) | 2017-03-24 |
| ES2606627T8 ES2606627T8 (es) | 2017-06-09 |
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| Application Number | Title | Priority Date | Filing Date |
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| ES11728594.0T Active ES2606627T3 (es) | 2010-05-28 | 2011-05-27 | Anticuerpos específicos anti-CD160 para el tratamiento de trastornos oculares basados en la neoangiogénesis |
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| Country | Link |
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| US (2) | US9045544B2 (OSRAM) |
| EP (1) | EP2575881B1 (OSRAM) |
| JP (1) | JP5990511B2 (OSRAM) |
| KR (1) | KR101847572B1 (OSRAM) |
| CN (2) | CN107648605A (OSRAM) |
| BR (1) | BR112012030318A2 (OSRAM) |
| CA (1) | CA2796312C (OSRAM) |
| DK (1) | DK2575881T3 (OSRAM) |
| ES (1) | ES2606627T3 (OSRAM) |
| PL (1) | PL2575881T3 (OSRAM) |
| WO (1) | WO2011147984A1 (OSRAM) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US10561707B2 (en) * | 2013-09-08 | 2020-02-18 | Technion Research And Development Foundation Ltd. | Semaphorin 3C variants, compositions comprising said variants and methods of use thereof in treating eye diseases |
| US20170056469A1 (en) * | 2014-05-02 | 2017-03-02 | Mayo Foundation For Medical Education And Research | Individualized treatment of eye disease |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| AU2016381964B2 (en) | 2015-12-30 | 2024-02-15 | Kodiak Sciences Inc. | Antibodies and conjugates thereof |
| KR20190084264A (ko) * | 2016-10-25 | 2019-07-16 | 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) | Cd160 막 횡단 동형체에 결합하는 단클론 항체 |
| FR3061716B1 (fr) * | 2017-01-06 | 2019-05-17 | Elsalys Biotech | Nouveaux composes ciblant le cd160 humain |
| CN111344002A (zh) * | 2017-08-31 | 2020-06-26 | 新加坡保健服务集团 | 用于治疗视网膜血管生成性疾病的Angio-3 |
| CN112203679A (zh) | 2018-03-02 | 2021-01-08 | 科达制药股份有限公司 | Il-6抗体及其融合构建体和缀合物 |
| CA3157509A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| WO2021138409A2 (en) * | 2019-12-31 | 2021-07-08 | Medstar Health, Inc. | Anti-cd160 binding molecules for treating diseases |
| CN116368154A (zh) | 2020-10-08 | 2023-06-30 | 阿菲姆德股份有限公司 | 三特异性结合剂 |
| JP2024529381A (ja) | 2021-07-30 | 2024-08-06 | アフィメド ゲーエムベーハー | デュプレックスボディ |
| EP4587123A1 (en) | 2022-09-15 | 2025-07-23 | Avidicure IP B.V. | Multispecific antigen binding proteins for tumor-targeting of nk cells and use thereof |
| WO2025191136A1 (en) | 2024-03-15 | 2025-09-18 | Avidicure Ip B.V. | Muteins of 4-1bb ligand extracellular domain, fusion proteins comprising the same and uses thereof |
| WO2025191133A1 (en) | 2024-03-15 | 2025-09-18 | Avidicure Ip B.V. | Il-21 muteins, fusion proteins comprising the same and uses thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3785186T2 (de) | 1986-09-02 | 1993-07-15 | Enzon Lab Inc | Bindungsmolekuele mit einzelpolypeptidkette. |
| EP1136556B1 (en) | 1991-11-25 | 2005-06-08 | Enzon, Inc. | Method of producing multivalent antigen-binding proteins |
| SG55079A1 (en) | 1992-12-11 | 1998-12-21 | Dow Chemical Co | Multivalent single chain antibodies |
| WO1998021240A1 (en) | 1996-11-12 | 1998-05-22 | Dana-Farber Cancer Institute | Recombinant by55 and nucleic acids encoding same |
| US6884879B1 (en) * | 1997-04-07 | 2005-04-26 | Genentech, Inc. | Anti-VEGF antibodies |
| FR2794977B1 (fr) * | 1999-06-18 | 2003-10-31 | Commissariat Energie Atomique | Utilisation de compositions contenant des formes solubles d'hla-g dans le traitement de pathologies inflammatoires de la peau, et leur procede d'obtention |
| EP1626059A1 (en) * | 2004-08-09 | 2006-02-15 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Angiogenic and immunologic applications of anti-CD160 specific compounds obtainable from mAb CL1-R2 |
| CA2622312A1 (en) * | 2006-01-30 | 2007-08-02 | (Osi) Eyetech, Inc. | Combination therapy for the treatment of neovascular disorders |
| AR062239A1 (es) * | 2007-08-07 | 2008-10-22 | Civil De Estudios Superiores A | Composicion farmaceutica sinergica util para inhibir la neovascularizacion (angiogenesis) corneal y retinal, y de otros organos, en un humano o animal |
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Also Published As
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| DK2575881T3 (en) | 2017-01-09 |
| WO2011147984A1 (en) | 2011-12-01 |
| EP2575881A1 (en) | 2013-04-10 |
| US20130122006A1 (en) | 2013-05-16 |
| JP5990511B2 (ja) | 2016-09-14 |
| CN102892432A (zh) | 2013-01-23 |
| EP2575881B1 (en) | 2016-09-14 |
| JP2013528607A (ja) | 2013-07-11 |
| US10208124B2 (en) | 2019-02-19 |
| ES2606627T8 (es) | 2017-06-09 |
| PL2575881T3 (pl) | 2018-06-29 |
| BR112012030318A2 (pt) | 2017-06-20 |
| CA2796312C (en) | 2020-11-03 |
| CN107648605A (zh) | 2018-02-02 |
| KR101847572B1 (ko) | 2018-05-24 |
| US20150344572A1 (en) | 2015-12-03 |
| CA2796312A1 (en) | 2011-12-01 |
| KR20130086548A (ko) | 2013-08-02 |
| US9045544B2 (en) | 2015-06-02 |
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