ES2583281T3 - Anticuerpos anti-MST1R y usos de los mismos - Google Patents

Anticuerpos anti-MST1R y usos de los mismos Download PDF

Info

Publication number
ES2583281T3
ES2583281T3 ES10710107.3T ES10710107T ES2583281T3 ES 2583281 T3 ES2583281 T3 ES 2583281T3 ES 10710107 T ES10710107 T ES 10710107T ES 2583281 T3 ES2583281 T3 ES 2583281T3
Authority
ES
Spain
Prior art keywords
amino acid
seq
acid sequence
mst1r
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10710107.3T
Other languages
English (en)
Spanish (es)
Inventor
Reimi Kawaida
Toshiaki Ohtsuka
Toshinori Agatsuma
Philip Rodley
Sandra Miller
Ulrike Schubert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Sankyo Co Ltd
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Application granted granted Critical
Publication of ES2583281T3 publication Critical patent/ES2583281T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/91Transferases (2.)
    • G01N2333/912Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205Phosphotransferases in general
    • G01N2333/9121Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES10710107.3T 2009-02-10 2010-02-10 Anticuerpos anti-MST1R y usos de los mismos Active ES2583281T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15141109P 2009-02-10 2009-02-10
US151411P 2009-02-10
PCT/JP2010/052479 WO2010093055A1 (en) 2009-02-10 2010-02-10 Anti-mst1r antibodies and uses thereof

Publications (1)

Publication Number Publication Date
ES2583281T3 true ES2583281T3 (es) 2016-09-20

Family

ID=42227811

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10710107.3T Active ES2583281T3 (es) 2009-02-10 2010-02-10 Anticuerpos anti-MST1R y usos de los mismos

Country Status (18)

Country Link
US (1) US9403909B2 (https=)
EP (1) EP2396084B1 (https=)
JP (1) JP5714511B2 (https=)
KR (1) KR101745025B1 (https=)
CN (1) CN102438702B (https=)
AU (1) AU2010214301B2 (https=)
BR (1) BRPI1007979A2 (https=)
CA (1) CA2752136C (https=)
CO (1) CO6420322A2 (https=)
ES (1) ES2583281T3 (https=)
IL (1) IL214527A0 (https=)
MX (1) MX2011008456A (https=)
NZ (1) NZ594452A (https=)
RU (1) RU2534890C2 (https=)
SG (2) SG2014009195A (https=)
TW (1) TWI480050B (https=)
WO (1) WO2010093055A1 (https=)
ZA (1) ZA201105725B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX356749B (es) * 2012-04-27 2018-06-12 Daiichi Sankyo Co Ltd Anticuerpo anti-homologo 4 de roundabout (robo4).
TWI909341B (zh) 2015-09-24 2025-12-21 日商第一三共股份有限公司 抗garp抗體及其製造方法及用途
EP3504244A4 (en) 2016-08-26 2020-08-19 Agency for Science, Technology and Research MACROPHAGE-STIMULATING PROTEIN RECEPTOR ANTIBODIES (OR OF NANTAIS ORIGINAL RON-RECEPTOR) AND THEIR USES
MX2022001812A (es) 2019-08-12 2022-03-11 Regeneron Pharma Variantes del receptor estimulante de macrofagos 1 (mst1r) y sus usos.
WO2021066751A1 (en) * 2019-10-02 2021-04-08 Aslan Pharmaceuticals Pte. Ltd. Antigen specific binding domains and antibody molecules
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU725609C (en) 1995-08-18 2002-01-03 Morphosys Ag Protein/(poly)peptide libraries
ES2327382T3 (es) 1999-07-20 2009-10-29 Morphosys Ag Metodos para presentar (poli)peptidos/proteinas en particulas de bacteriofagos a traves de enlaces disulfuro.
CA2566647A1 (en) * 2004-05-13 2005-12-22 Imclone Systems Incorporated Inhibition of macrophage-stimulating protein receptor (ron)
US20060073256A1 (en) * 2004-06-15 2006-04-06 Frederic Destaillats Self-foaming liquid creamers and processes
JP2008512352A (ja) * 2004-07-17 2008-04-24 イムクローン システムズ インコーポレイティド 新規な四価の二重特異性抗体
UY31478A1 (es) * 2007-11-21 2009-07-17 Inhibicion del receptor para la proteina estimulante del macrofago (ron) y métodos para el tratamiento de lo mismo
MX2010008025A (es) * 2008-01-22 2010-08-04 Biogen Idec Inc Anticuerpos ron y usos de los mismos.

Also Published As

Publication number Publication date
EP2396084B1 (en) 2016-05-11
AU2010214301A1 (en) 2011-09-01
US9403909B2 (en) 2016-08-02
KR20110117677A (ko) 2011-10-27
WO2010093055A1 (en) 2010-08-19
TW201036635A (en) 2010-10-16
SG173196A1 (en) 2011-08-29
IL214527A0 (en) 2011-09-27
KR101745025B1 (ko) 2017-06-20
US20120034215A1 (en) 2012-02-09
HK1164193A1 (zh) 2012-09-21
CO6420322A2 (es) 2012-04-16
RU2534890C2 (ru) 2014-12-10
RU2011137405A (ru) 2013-03-20
TWI480050B (zh) 2015-04-11
JP5714511B2 (ja) 2015-05-07
EP2396084A1 (en) 2011-12-21
ZA201105725B (en) 2012-04-25
MX2011008456A (es) 2011-09-26
AU2010214301B2 (en) 2016-11-10
SG2014009195A (en) 2014-04-28
BRPI1007979A2 (pt) 2017-10-03
CN102438702A (zh) 2012-05-02
JP2012517223A (ja) 2012-08-02
CA2752136A1 (en) 2010-08-19
CN102438702B (zh) 2016-03-02
CA2752136C (en) 2016-03-15
NZ594452A (en) 2013-01-25

Similar Documents

Publication Publication Date Title
US8858938B2 (en) Human monoclonal antibodies against Hendra and Nipah viruses
ES2573404T3 (es) Anticuerpos contra un ligando inductor de proliferación (APRIL)
ES2583281T3 (es) Anticuerpos anti-MST1R y usos de los mismos
CN104936984B (zh) 特异性结合人和小鼠l1cam的抗体及其用途
KR20150041801A (ko) 복합체-특이적 항체 및 항체 단편 및 그의 용도
AU2018242152B2 (en) Compositions and methods for detecting prostate cancer
JP2018535922A (ja) 抗N−メチル−D−アスパラギン酸(NMDA)受容体抗体の結合領域に結合する抗体または抗体フラグメントまたは非Ig足場
CN109053884A (zh) Wasabi蛋白纳米抗体及其编码序列与应用
EP3947452A1 (en) Anti-nmda receptor antibodies and methods of use
KR20120002641A (ko) 비브리오균의 외막단백질에 대한 항체 및 이를 이용한 상기 균의 검출 방법
GB2483998A (en) Nucleic acid sequencing-based methods of analyzing affinities of libraries of binding compounds
CN110642947B (zh) 抗人cd147的单克隆抗体、表达载体、细胞株及其应用
Xu et al. Two monoclonal antibodies to precisely the same epitope of type II collagen select non-crossreactive phage clones by phage display: implications for autoimmunity and molecular mimicry
AU2012200557B2 (en) Human monoclonal antibodies against Hendra and Nipah viruses
US20260023075A1 (en) Antibodies and biosensors for detection of pfas compounds
KR102688094B1 (ko) Cobll1 단백질 특이 항체 또는 이의 항원 결합 단편, 및 이의 용도
CN104650224B (zh) 一种针对sea的纳米抗体及其编码序列与应用