ES2582582T3 - Células madre de tipo blastómero para uso en el tratamiento de trastorno proliferativo celular e inmunodeficiencia - Google Patents

Células madre de tipo blastómero para uso en el tratamiento de trastorno proliferativo celular e inmunodeficiencia Download PDF

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Publication number
ES2582582T3
ES2582582T3 ES10746666.6T ES10746666T ES2582582T3 ES 2582582 T3 ES2582582 T3 ES 2582582T3 ES 10746666 T ES10746666 T ES 10746666T ES 2582582 T3 ES2582582 T3 ES 2582582T3
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stem cells
cells
blscs
subject
cancer
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ES10746666.6T
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English (en)
Spanish (es)
Inventor
James Wang
Lufen Chang
Yun Yen
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Stembios Technologies Inc
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Stembios Technologies Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/54Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/20Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/22Immunosuppressive or immunotolerising
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/416Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/38Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0607Non-embryonic pluripotent stem cells, e.g. MASC
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ES10746666.6T 2009-02-24 2010-02-19 Células madre de tipo blastómero para uso en el tratamiento de trastorno proliferativo celular e inmunodeficiencia Active ES2582582T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/391,581 US8563307B2 (en) 2009-02-24 2009-02-24 Treatment of immunosuppression-related disorders
US391581 2009-02-24
PCT/US2010/024735 WO2010099044A2 (en) 2009-02-24 2010-02-19 Treatment of immunosuppression-related disorders

Publications (1)

Publication Number Publication Date
ES2582582T3 true ES2582582T3 (es) 2016-09-13

Family

ID=42631141

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10746666.6T Active ES2582582T3 (es) 2009-02-24 2010-02-19 Células madre de tipo blastómero para uso en el tratamiento de trastorno proliferativo celular e inmunodeficiencia

Country Status (7)

Country Link
US (2) US8563307B2 (OSRAM)
EP (1) EP2400971B1 (OSRAM)
JP (1) JP5809068B2 (OSRAM)
CN (1) CN102325537B (OSRAM)
ES (1) ES2582582T3 (OSRAM)
TW (1) TWI496888B (OSRAM)
WO (1) WO2010099044A2 (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8563307B2 (en) 2009-02-24 2013-10-22 James Wang Treatment of immunosuppression-related disorders
US8679474B2 (en) 2010-08-04 2014-03-25 StemBios Technologies, Inc. Somatic stem cells
WO2012054792A2 (en) * 2010-10-22 2012-04-26 Virginia Commonwealth University Composition and method for immunological treatment of cancer, prevention of cancer recurrence and metastasis, and overcoming immune suppressor cells
TWI571513B (zh) 2011-09-28 2017-02-21 幹細胞生物科技股份有限公司 體幹細胞及其製備方法
WO2013176785A1 (en) * 2012-05-21 2013-11-28 The Trustees Of Columbia University In The City Of New York Trefoil family factor and uses thereof
JP6495174B2 (ja) 2012-12-06 2019-04-03 ステムバイオス テクノロジーズ,インコーポレイテッド Lgr5+体性幹細胞
EP2746770A1 (en) * 2012-12-21 2014-06-25 Stembios Technologies, Inc. Method for evaluating effect of action on subject based on stem celldynamics
US9212225B1 (en) * 2014-07-01 2015-12-15 Amphivena Therapeutics, Inc. Bispecific CD33 and CD3 binding proteins
CN114652827A (zh) 2015-05-29 2022-06-24 安普希韦纳治疗公司 双特异性cd33和cd3结合蛋白质的使用方法

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2936171B2 (ja) 1989-09-01 1999-08-23 東ソー株式会社 血清アルブミンの製造方法
US6004807A (en) 1992-03-30 1999-12-21 Schering Corporation In vitro generation of human dendritic cells
US6916654B1 (en) 1992-06-29 2005-07-12 Oklahoma Medical Research Foundation Universal donor cells
AU6869198A (en) 1997-03-25 1998-10-20 Morphogenesis, Inc. Universal stem cells
AU1705599A (en) 1997-11-26 1999-06-15 Allegheny University Of The Health Sciences Methods for mobilizing hematopoietic facilitating cells and hematopoietic stem cells into the peripheral blood
CA2347067C (en) 1998-03-31 2013-09-17 Geron Corporation Dendritic cell vaccine containing telomerase reverse transcriptase for the treatment of cancer
US6080399A (en) 1998-04-23 2000-06-27 Arch Development Corporation Vaccine adjuvants for immunotherapy of melanoma
JP3553858B2 (ja) 1999-08-25 2004-08-11 東洋紡績株式会社 血管網類似構造体を有する細胞培養用モジュール
US20030161817A1 (en) 2001-03-28 2003-08-28 Young Henry E. Pluripotent embryonic-like stem cells, compositions, methods and uses thereof
US7575921B2 (en) 1999-12-30 2009-08-18 Vbi Technologies, L.L.C. Spore-like cells and uses thereof
US20020151050A1 (en) 2000-10-30 2002-10-17 Vacanti Charles A. Isolation of spore-like cells from tissues exposed to extreme conditions
JP3977136B2 (ja) 2001-05-22 2007-09-19 キヤノン株式会社 コイルユニット
US7316932B2 (en) 2001-10-01 2008-01-08 Stemcell Technologies Inc. Method for separating cells
US7736892B2 (en) 2002-02-25 2010-06-15 Kansas State University Research Foundation Cultures, products and methods using umbilical cord matrix cells
EP1481249A1 (en) 2002-03-07 2004-12-01 Cambridge University Technical Services Limited Scd fingerprints
ES2369077T3 (es) 2002-06-06 2011-11-25 Immunicum Ab Nuevo procedimiento y composición para producir una vacuna alogénica celular.
US20050244970A1 (en) 2002-11-01 2005-11-03 Hongbing Zhang Stem cell libraries
WO2004044158A2 (en) 2002-11-08 2004-05-27 The Johns Hopkins University Human embryonic stem cell cultures, and compositions and methods for growing same
US20050003533A1 (en) 2003-05-08 2005-01-06 Pawel Kalinski Mature type-1 polarized dendritic cells with enhanced IL-12 production and methods of serum-free production and use
US20090004661A1 (en) 2003-05-26 2009-01-01 Reliance Life Sciences Pvt Ltd. Method of growing mesenchymal stem cells from bone marrow
ES2265199B1 (es) 2003-06-12 2008-02-01 Cellerix, S.L. Celulas madre adultas multipotentes procedentes de condrocitos desdiferenciados y sus aplicaciones.
AU2004249812B8 (en) 2003-06-25 2011-09-15 Ottawa Hospital Research Institute Methods and compositions for modulating stem cell growth and differentiation
US7622108B2 (en) 2004-04-23 2009-11-24 Bioe, Inc. Multi-lineage progenitor cells
WO2006028723A1 (en) * 2004-09-03 2006-03-16 Moraga Biotechnology Inc. Non-embryonic totipotent blastomer-like stem cells and methods therefor
EP2410043A3 (en) 2004-12-29 2013-01-23 Hadasit Medical Research Services And Development Ltd. Stem cells culture systems
US8846395B2 (en) 2005-06-01 2014-09-30 Wisconsin Alumni Research Foundation Generation of mature myelomonocytic cells through expansion and differentiation of pluripotent stem cell-derived lin-CD34+CD43+CD45+progenitors
WO2007002570A1 (en) 2005-06-24 2007-01-04 Desert Lake Technologies Purified component of blue-green algae and method of use
US8476070B2 (en) 2005-08-29 2013-07-02 Technion Research & Development Foundation Limited Media for culturing stem cells
US20080305079A1 (en) 2006-01-06 2008-12-11 Mount Sinai School Of Medicine Of New York University Myeloid Suppressor Cells, Methods For Preparing Them, and Methods For Using Them For Treating Autoimmunity
CA2640087A1 (en) 2006-01-25 2007-08-02 Mount Sinai School Of Medicine Methods and compositions for modulating the mobilization of stem cells
EP1991666A4 (en) 2006-02-27 2009-06-10 Moraga Biotech Corp NON-EMBRYONIC TOTIPOTENT STEM CELLS OF BLASTOMERIC TYPE AND METHODS
CA2656160A1 (en) 2006-06-27 2008-01-03 Nutratec S.R.L. Extracts of aphanizomenon flos aquae and nutritional, cosmetic and pharmaceutical compositions containing the same
EP1894941A1 (en) 2006-09-01 2008-03-05 Institut Pasteur Treatment of cervical carcinoma with a recombinant adenylate cyclase carrying HPV antigens
US8759090B2 (en) 2006-10-30 2014-06-24 University Of Central Florida Research Foundation, Inc. Stem cell banking system
US20090104160A1 (en) 2007-02-01 2009-04-23 Moraga Biotechnology Corporation Mobilization of Stem Cells After Trauma and Methods Therefor
US20090053182A1 (en) 2007-05-25 2009-02-26 Medistem Laboratories, Inc. Endometrial stem cells and methods of making and using same
HRP20151261T1 (hr) 2007-07-02 2016-01-01 Oncomed Pharmaceuticals, Inc. Sastavi i postupci za lijeäśenje i dijagnosticiranje raka
CA2693144A1 (en) 2007-07-17 2009-01-22 The General Hospital Corporation Methods to identify and enrich for populations of ovarian cancer stem cells and somatic ovarian stem cells and uses thereof
EP2214497A4 (en) 2007-10-30 2010-11-24 Univ Louisville Res Found USES AND ISOLATION OF VERY SMALL EMBRYONIC TYPE STEM CELLS (VSEL)
EP2205724B1 (en) 2007-11-09 2016-04-27 RNL Bio Co., Ltd. Method for isolating and culturing adult stem cells derived from human amniotic epithelium
GB2467982A (en) 2008-05-08 2010-08-25 Coretherapix Slu Pluripotent adult stem cells
WO2010039241A1 (en) 2008-09-30 2010-04-08 University Of Louisville Research Foundation, Inc. Methods for isolating very small embryonic-like (vsel) stem cells
WO2010056341A2 (en) 2008-11-12 2010-05-20 The University Of Vermont And State Agriculture College Compositions and methods for tissue repair
WO2010083203A2 (en) * 2009-01-13 2010-07-22 StemBios Technologies, Inc. Non-embryonic stem cells and uses thereof
EP3061808B1 (en) 2009-02-03 2020-08-12 Koninklijke Nederlandse Akademie van Wetenschappen Culture medium for epithelial stem cells and organoids comprising said stem cells
EP2412800A1 (en) 2010-07-29 2012-02-01 Koninklijke Nederlandse Akademie van Wetenschappen Liver organoid, uses thereof and culture method for obtaining them
US8563307B2 (en) 2009-02-24 2013-10-22 James Wang Treatment of immunosuppression-related disorders
EP2549992B1 (en) 2010-03-23 2019-08-14 The Johns Hopkins University Methods of treatment using stem cell mobilizers
CA2835313A1 (en) 2010-05-07 2011-11-10 Institut De Recherches Cliniques De Montreal Gfi1b modulation and uses thereof
EP3569696A1 (en) 2010-08-04 2019-11-20 Stembios Technologies, Inc. Somatic stem cells
US8679474B2 (en) 2010-08-04 2014-03-25 StemBios Technologies, Inc. Somatic stem cells
CN102008650B (zh) 2010-12-16 2017-02-15 天津市医药科学研究所 一种治疗肿瘤的复方中药制剂及其制备方法
TWI571513B (zh) 2011-09-28 2017-02-21 幹細胞生物科技股份有限公司 體幹細胞及其製備方法
JP6495174B2 (ja) 2012-12-06 2019-04-03 ステムバイオス テクノロジーズ,インコーポレイテッド Lgr5+体性幹細胞
US20140377760A1 (en) 2013-06-24 2014-12-25 StemBios Technologies, Inc. Method for increasing number of stem cells in human or animal bodies
CN105687245A (zh) 2014-12-13 2016-06-22 干细胞生物科技公司 制备注射液的方法

Also Published As

Publication number Publication date
JP2012518646A (ja) 2012-08-16
US20100215622A1 (en) 2010-08-26
CN102325537B (zh) 2014-07-30
JP5809068B2 (ja) 2015-11-10
US9770473B2 (en) 2017-09-26
TWI496888B (zh) 2015-08-21
EP2400971B1 (en) 2016-05-18
WO2010099044A2 (en) 2010-09-02
US8563307B2 (en) 2013-10-22
EP2400971A1 (en) 2012-01-04
WO2010099044A9 (en) 2010-12-16
US20140030237A1 (en) 2014-01-30
CN102325537A (zh) 2012-01-18
TW201040278A (en) 2010-11-16
EP2400971A4 (en) 2013-03-27

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