ES2571452T3 - Compuesto antagonista de leucotrieno B4 - Google Patents
Compuesto antagonista de leucotrieno B4Info
- Publication number
- ES2571452T3 ES2571452T3 ES13701305T ES13701305T ES2571452T3 ES 2571452 T3 ES2571452 T3 ES 2571452T3 ES 13701305 T ES13701305 T ES 13701305T ES 13701305 T ES13701305 T ES 13701305T ES 2571452 T3 ES2571452 T3 ES 2571452T3
- Authority
- ES
- Spain
- Prior art keywords
- leukotriene
- antagonist compound
- compound
- formula
- antagonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000003913 leukotriene B4 receptor antagonist Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261584975P | 2012-01-10 | 2012-01-10 | |
| US201261585799P | 2012-01-12 | 2012-01-12 | |
| PCT/US2013/020195 WO2013106238A1 (en) | 2012-01-10 | 2013-01-04 | Leukotriene b4 antagonist compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2571452T3 true ES2571452T3 (es) | 2016-05-25 |
Family
ID=47604162
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES13701305T Active ES2571452T3 (es) | 2012-01-10 | 2013-01-04 | Compuesto antagonista de leucotrieno B4 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9187411B2 (enExample) |
| EP (1) | EP2802557B1 (enExample) |
| JP (1) | JP2015509917A (enExample) |
| KR (1) | KR20140099546A (enExample) |
| CN (1) | CN104011012B (enExample) |
| AU (1) | AU2013208260A1 (enExample) |
| BR (1) | BR112014016450A2 (enExample) |
| CA (1) | CA2857521C (enExample) |
| EA (1) | EA023067B1 (enExample) |
| ES (1) | ES2571452T3 (enExample) |
| IN (1) | IN2014MN01014A (enExample) |
| MX (1) | MX2014008452A (enExample) |
| WO (1) | WO2013106238A1 (enExample) |
| ZA (1) | ZA201404732B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3383868B1 (en) | 2015-11-30 | 2022-10-05 | Merck Sharp & Dohme LLC | Aryl sulfonamides as blt1 antagonists |
| WO2017095722A1 (en) | 2015-11-30 | 2017-06-08 | Merck Sharp & Dohme Corp. | Aryl acylsulfonamides as blt1 antagonists |
| US10450309B2 (en) | 2015-11-30 | 2019-10-22 | Merch Sharp & Dohme Corp. | Aryl sulfonamides as BLT1 antagonists |
| US10370368B2 (en) | 2015-11-30 | 2019-08-06 | Merck Sharp & Dohme Corp. | Aryl acylsulfonamides as BLT1 antagonists |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5105017A (en) * | 1983-07-18 | 1992-04-14 | Eli Lilly And Company | Leukotriene antagonist intermediates |
| GB9027023D0 (en) | 1990-12-12 | 1991-01-30 | Wellcome Found | Anti-atherosclerotic aryl compounds |
| PH30449A (en) | 1991-11-25 | 1997-05-28 | Lilly Co Eli | Substituted phenyl phenol leukotriene antagonists |
| CN1035001C (zh) * | 1993-01-02 | 1997-05-28 | 伊莱利利公司 | 取代的苯基苯酚基白三烯拮抗物 |
| EP0743064A1 (en) * | 1995-05-17 | 1996-11-20 | Eli Lilly And Company | Leukotriene antagonists for use in the treatment or prevention of alzheimer's disease |
| AU6572298A (en) | 1997-03-21 | 1998-10-20 | Eli Lilly And Company | Leukotriene antagonists useful for treating ischemia reperfusion injury |
| EP1231939A2 (en) | 1999-11-11 | 2002-08-21 | Eli Lilly And Company | Oncolytic combinations for the treatment of cancer |
| WO2001034198A2 (en) | 1999-11-11 | 2001-05-17 | Eli Lilly And Company | Oncolytic combinations for the treatment of cancer |
| AU2001261832A1 (en) | 2000-05-09 | 2001-11-20 | Creighton University | Methods for inhibiting proliferation and inducing apoptosis in cancer cells |
| WO2001094333A2 (en) * | 2000-06-02 | 2001-12-13 | Eli Lilly & Company | Process for the preparation of benzoyl substituted bicyclic compounds and chiral benzopyran derivatives |
| BRPI0407180A (pt) | 2003-02-14 | 2006-02-07 | Lilly Co Eli | Composto, composição farmacêutica, métodos para modular um receptor ativado pelo proliferador de peroxissoma, para tratar ou prevenir uma doença ou condição, para diminuir a glicose no sangue em um mamìfero, para tratar ou prevenir diabetes mellitus, doença cardiovascular e sìndrome x em um mamìfero, e, uso de um composto |
-
2013
- 2013-01-04 KR KR1020147018769A patent/KR20140099546A/ko not_active Withdrawn
- 2013-01-04 EA EA201491099A patent/EA023067B1/ru not_active IP Right Cessation
- 2013-01-04 WO PCT/US2013/020195 patent/WO2013106238A1/en not_active Ceased
- 2013-01-04 ES ES13701305T patent/ES2571452T3/es active Active
- 2013-01-04 AU AU2013208260A patent/AU2013208260A1/en not_active Abandoned
- 2013-01-04 BR BR112014016450A patent/BR112014016450A2/pt not_active IP Right Cessation
- 2013-01-04 CN CN201380004537.9A patent/CN104011012B/zh not_active Expired - Fee Related
- 2013-01-04 EP EP13701305.8A patent/EP2802557B1/en active Active
- 2013-01-04 JP JP2014552215A patent/JP2015509917A/ja not_active Withdrawn
- 2013-01-04 MX MX2014008452A patent/MX2014008452A/es unknown
- 2013-01-04 CA CA2857521A patent/CA2857521C/en not_active Expired - Fee Related
- 2013-01-04 US US14/359,924 patent/US9187411B2/en not_active Expired - Fee Related
-
2014
- 2014-05-26 IN IN1014MUN2014 patent/IN2014MN01014A/en unknown
- 2014-06-26 ZA ZA2014/04732A patent/ZA201404732B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2857521A1 (en) | 2013-07-18 |
| EA023067B1 (ru) | 2016-04-29 |
| CN104011012A (zh) | 2014-08-27 |
| US20140343151A1 (en) | 2014-11-20 |
| EA201491099A1 (ru) | 2014-11-28 |
| ZA201404732B (en) | 2015-11-25 |
| AU2013208260A1 (en) | 2014-06-05 |
| CA2857521C (en) | 2016-03-01 |
| JP2015509917A (ja) | 2015-04-02 |
| BR112014016450A2 (pt) | 2019-09-24 |
| WO2013106238A1 (en) | 2013-07-18 |
| EP2802557A1 (en) | 2014-11-19 |
| KR20140099546A (ko) | 2014-08-12 |
| MX2014008452A (es) | 2014-08-27 |
| EP2802557B1 (en) | 2016-04-06 |
| CN104011012B (zh) | 2016-01-20 |
| US9187411B2 (en) | 2015-11-17 |
| IN2014MN01014A (enExample) | 2015-07-03 |
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