ES2570973T3 - Productos y métodos para la estimulación de una respuesta inmunitaria - Google Patents
Productos y métodos para la estimulación de una respuesta inmunitariaInfo
- Publication number
- ES2570973T3 ES2570973T3 ES13189439T ES13189439T ES2570973T3 ES 2570973 T3 ES2570973 T3 ES 2570973T3 ES 13189439 T ES13189439 T ES 13189439T ES 13189439 T ES13189439 T ES 13189439T ES 2570973 T3 ES2570973 T3 ES 2570973T3
- Authority
- ES
- Spain
- Prior art keywords
- immune response
- lymphocyte
- antigen
- stimulating
- products
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Transplantation (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4981408P | 2008-05-02 | 2008-05-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2570973T3 true ES2570973T3 (es) | 2016-05-23 |
Family
ID=40888253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES13189439T Active ES2570973T3 (es) | 2008-05-02 | 2009-05-05 | Productos y métodos para la estimulación de una respuesta inmunitaria |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20110280930A1 (https=) |
| EP (3) | EP2711021B1 (https=) |
| JP (3) | JP5721620B2 (https=) |
| CN (1) | CN102170903B (https=) |
| AU (1) | AU2009241645B2 (https=) |
| CA (1) | CA2723226A1 (https=) |
| ES (1) | ES2570973T3 (https=) |
| WO (1) | WO2009133378A2 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2711021B1 (en) * | 2008-05-02 | 2016-03-09 | BliNK Therapeutics Limited | Products and methods for stimulating an immune response |
| WO2012088414A1 (en) * | 2010-12-23 | 2012-06-28 | Ludwig Institute For Cancer Research Ltd. | Liposomal formulation of nonglycosidic ceramides and uses thereof |
| US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
| EP2714017B1 (en) | 2011-06-02 | 2018-08-01 | The Regents of The University of California | Membrane encapsulated nanoparticles and method of use |
| TW201442739A (zh) * | 2013-02-27 | 2014-11-16 | Riken | 過敏疾病治療藥 |
| GB2514591A (en) | 2013-05-30 | 2014-12-03 | Mologen Ag | Predictive biomarker for cancer therapy |
| EP3024936B1 (en) | 2013-07-25 | 2019-09-04 | Exicure, Inc. | Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use |
| WO2015021390A2 (en) | 2013-08-08 | 2015-02-12 | The Regents Of The University Of California | Nanoparticles leverage biological membranes to target pathogens for disease treatment and diagnosis |
| US20170000875A1 (en) * | 2013-12-02 | 2017-01-05 | Arytha Biosciences, Llc | Toxoid preparation and uses thereof |
| CN106163504B (zh) | 2014-03-20 | 2021-02-09 | 加利福尼亚大学董事会 | 水凝胶毒素-吸收或结合纳米颗粒 |
| EP3137105A4 (en) | 2014-04-30 | 2017-12-27 | President and Fellows of Harvard College | Combination vaccine devices and methods of killing cancer cells |
| TR201908550T4 (tr) * | 2014-06-04 | 2019-07-22 | Exicure Inc | Profilaktik veya terapötik uygulamalar için lipozomal sferik nükleik asitler tarafından immün modülatörlerin çok değerlikli teslimi. |
| WO2016164705A1 (en) * | 2015-04-10 | 2016-10-13 | Omar Abdel-Rahman Ali | Immune cell trapping devices and methods for making and using the same |
| WO2016176041A1 (en) | 2015-04-29 | 2016-11-03 | The Regents Of The University Of California | Detoxification using nanoparticles |
| JP2018516996A (ja) * | 2015-06-10 | 2018-06-28 | ウニヴェルズィテート・デ・ザールラントUniversitaet Des Saarlandes | B細胞悪性腫瘍を処置するための手段および方法 |
| US11752238B2 (en) | 2016-02-06 | 2023-09-12 | President And Fellows Of Harvard College | Recapitulating the hematopoietic niche to reconstitute immunity |
| WO2017211314A1 (en) | 2016-06-08 | 2017-12-14 | Kei International Limited | Method for detecting presence of mycobacterial material in sample using immobilised mannosyl phosphoketide antigen |
| NL2017204B1 (en) | 2016-06-08 | 2017-12-18 | Kei International Ltd | Solid substrate comprising antigens immobilised thereto, biosensor comprising said solid substrate and method for detecting the presence of mycobacterial material in a sample |
| CN109789092A (zh) | 2016-07-13 | 2019-05-21 | 哈佛学院院长等 | 抗原呈递细胞模拟支架及其制备和使用方法 |
| IL264557B2 (en) | 2016-08-02 | 2024-01-01 | Harvard College | Biological agents for regulating immune responses |
| US20190365657A1 (en) * | 2016-08-17 | 2019-12-05 | Orbis Health Solutions, Llc | Tumor-targeting bead vectors and methods of using the same |
| WO2019032862A1 (en) * | 2017-08-10 | 2019-02-14 | Dana-Farber Cancer Institute, Inc. | CELLS EXPRESSING LMP1 AND METHODS OF USE |
| NL2021443B1 (en) | 2018-08-08 | 2020-02-20 | Kei International Ltd | Synthetic antigens for tuberculosis detection |
| WO2020061129A1 (en) | 2018-09-19 | 2020-03-26 | President And Fellows Of Harvard College | Compositions and methods for labeling and modulation of cells in vitro and in vivo |
| EP3650466A1 (en) * | 2018-11-12 | 2020-05-13 | Consejo Superior De Investigaciones Científicas | In vitro production of high affinity monoclonal antibodies |
| CN111229023B (zh) * | 2018-11-29 | 2022-01-28 | 内蒙古东盛硅藻土科技创新产业园有限公司 | 一种化学降解添加剂 |
| WO2021061837A1 (en) | 2019-09-23 | 2021-04-01 | President And Fellows Of Harvard College | Biomaterial-based antigen free vaccine and the use thereof |
| CN112300987B (zh) * | 2020-10-16 | 2022-04-29 | 中国农业大学 | 单个浆细胞的筛选方法及其在小分子单克隆抗体制备中的应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK590288D0 (da) | 1988-10-24 | 1988-10-24 | Symbicom Ab | Kemiske forbindelser |
| DK0506868T4 (da) | 1989-12-22 | 2004-04-26 | Mikrogen Molekularbiol Entw | Immunologisk aktive proteiner fra Borrelia burgdorferi, tilhørende testkits og vaccine |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| FI933580A7 (fi) | 1991-02-15 | 1993-10-13 | Uab Research Foundation | Pneumokokkiproteiinin rakennegeeni |
| US6113914A (en) | 1991-08-15 | 2000-09-05 | Smithkline Beecham Biologicals (S.A.) | Osp A proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines |
| ES2194010T3 (es) | 1991-10-22 | 2003-11-16 | Symbicom Ab | Mejoras en el diagnostico y profilaxis de la borrelia burgdorferi. |
| US5776427A (en) | 1992-03-05 | 1998-07-07 | Board Of Regents, The University Of Texas System | Methods for targeting the vasculature of solid tumors |
| US6004763A (en) * | 1992-09-11 | 1999-12-21 | Institut Pasteur | Antigen-carrying microparticles and their use in the induction of humoral or cellular responses |
| FR2695563B1 (fr) * | 1992-09-11 | 1994-12-02 | Pasteur Institut | Microparticules portant des antigènes et leur utilisation pour l'induction de réponses humorales ou cellulaires. |
| EP0773993A4 (en) | 1994-08-19 | 2000-07-05 | Gen Hospital Corp | PORCINE CELLS TREATED BY GENETIC ENGINEERING |
| EP1434859A2 (en) | 2001-07-25 | 2004-07-07 | New York University | Use of glycosylceramides as adjuvants for vaccines against infections and cancer |
| DE10164309A1 (de) * | 2001-12-28 | 2003-07-10 | Fraunhofer Ges Forschung | Verbesserte strukturiert-funktionale Bindematrices für Biomoleküle |
| CN100455600C (zh) * | 2002-08-14 | 2009-01-28 | 阿维迪斯公司 | 包含支架,佐剂和抗原的异源多聚体化合物及其用途 |
| AU2004215125B2 (en) | 2003-02-26 | 2011-01-06 | Institute For Research In Biomedicine | Monoclonal antibody production by EBV transformation of B cells |
| US20050175583A1 (en) * | 2003-12-02 | 2005-08-11 | Lawrence Tamarkin | Methods and compositions for the production of monoclonal antibodies |
| EP1767216B1 (en) | 2004-06-11 | 2012-07-11 | Riken | Drug having regulatory cell ligand contained in liposome |
| JP4987704B2 (ja) * | 2004-07-07 | 2012-07-25 | スタテンス セールム インスティトゥート | 糖脂質を用いた、脂質系アジュバント製剤を安定化する組成物及び方法 |
| EP1793863B1 (en) * | 2004-10-01 | 2017-04-12 | Midatech Ltd. | Nanoparticles comprising antigens and adjuvants capable of stimulating t helper cells |
| US20080138431A1 (en) * | 2005-03-02 | 2008-06-12 | James Edward Eyles | Pharmaceutical Composition |
| BRPI0617687A2 (pt) | 2005-10-25 | 2011-08-02 | Ludwig Inst Cancer Res | composto, método para proteger um indivìduo mamìfero contra, ou tratar, um vìrus, infecção microbiana, parasita, uma doença auto-imune, cáncer, alergia ou asma, e, composição farmacêutica |
| WO2007051004A2 (en) | 2005-10-28 | 2007-05-03 | The Brigham And Women's Hospital, Inc. | Conjugate vaccines for non-proteinaceous antigens |
| US20070231344A1 (en) | 2005-10-28 | 2007-10-04 | The Brigham And Women's Hospital, Inc. | Conjugate vaccines for non-proteinaceous antigens |
| EP2711021B1 (en) * | 2008-05-02 | 2016-03-09 | BliNK Therapeutics Limited | Products and methods for stimulating an immune response |
| JP5782775B2 (ja) | 2011-03-29 | 2015-09-24 | ソニー株式会社 | 情報表示装置および情報表示方法、並びにプログラム |
-
2009
- 2009-05-05 EP EP13189439.6A patent/EP2711021B1/en not_active Not-in-force
- 2009-05-05 EP EP09738408A patent/EP2288381A2/en not_active Withdrawn
- 2009-05-05 WO PCT/GB2009/001111 patent/WO2009133378A2/en not_active Ceased
- 2009-05-05 JP JP2011506772A patent/JP5721620B2/ja not_active Expired - Fee Related
- 2009-05-05 CA CA2723226A patent/CA2723226A1/en not_active Abandoned
- 2009-05-05 ES ES13189439T patent/ES2570973T3/es active Active
- 2009-05-05 US US12/736,706 patent/US20110280930A1/en not_active Abandoned
- 2009-05-05 CN CN200980125581.9A patent/CN102170903B/zh not_active Expired - Fee Related
- 2009-05-05 AU AU2009241645A patent/AU2009241645B2/en not_active Ceased
- 2009-05-05 EP EP13189438.8A patent/EP2711020B1/en not_active Not-in-force
-
2014
- 2014-08-07 JP JP2014160906A patent/JP2015028023A/ja active Pending
- 2014-08-07 JP JP2014160907A patent/JP5853068B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2711020A1 (en) | 2014-03-26 |
| EP2711020B1 (en) | 2016-08-10 |
| HK1190942A1 (en) | 2014-07-18 |
| EP2711021B1 (en) | 2016-03-09 |
| WO2009133378A3 (en) | 2009-12-23 |
| CA2723226A1 (en) | 2009-05-11 |
| HK1191548A1 (en) | 2014-08-01 |
| CN102170903B (zh) | 2016-04-06 |
| EP2711021A1 (en) | 2014-03-26 |
| JP5853068B2 (ja) | 2016-02-09 |
| AU2009241645A1 (en) | 2009-11-05 |
| EP2288381A2 (en) | 2011-03-02 |
| AU2009241645B2 (en) | 2014-07-17 |
| JP2015028023A (ja) | 2015-02-12 |
| CN102170903A (zh) | 2011-08-31 |
| HK1161542A1 (zh) | 2012-07-27 |
| JP5721620B2 (ja) | 2015-05-20 |
| JP2015038066A (ja) | 2015-02-26 |
| WO2009133378A2 (en) | 2009-11-05 |
| JP2011519847A (ja) | 2011-07-14 |
| US20110280930A1 (en) | 2011-11-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2570973T3 (es) | Productos y métodos para la estimulación de una respuesta inmunitaria | |
| AR074501A1 (es) | Oligonucleotidos inmunoestimuladores | |
| MX2010000781A (es) | Metodo para adherir una pelicula sobre un sustrato curvo. | |
| CR20110087A (es) | Metodo y montaje para productos tri-dimencionales | |
| WO2010115122A3 (en) | Generation of uniform fragments of nucleic acids using patterned substrates | |
| CR10559A (es) | Vacuna de influenza | |
| EP1992479A4 (en) | FILM SUBSTRATE OF A PRIMED SEPARATE FOIL, embossed release sheet, method of making a sheet stock from a sewn release sheet, method of making a sewn release sheet, a device for making a sewn release sheet, an artificial leather, and method of making an artificial leather | |
| DK2468300T3 (da) | Vaccinesammensætning indeholdende syntetisk adjuvant | |
| JP2011519847A5 (https=) | ||
| WO2008127296A3 (en) | Methods and compositions for treating tularemia | |
| WO2006020889A3 (en) | Dendritic cell vaccines for treating cancer made from embryonic stem cells | |
| AR072151A1 (es) | Metodo para producir lentes de contacto de hidrogel de silicona | |
| BR112013014265A8 (pt) | sequência de ácido nucleico isolada, receptor antígeno quimérico isolado, célula, vetor, e, métodos para estimular uma resposta imune mediada por célula t, para fornecer uma imunidade antitumoral em um mamífero, para tratar um mamífero tendo uma doença, distúrbio ou condição, para tratar um ser humano com uma doença, para gerar uma população persistente de célula t, e para expandir uma população de célula t | |
| MX2009012991A (es) | Metodo para obtener un sustrato texturizado para un panel fotovoltaico. | |
| NZ577405A (en) | Vaccines including antigen from four strains of influenza virus | |
| AR042549A1 (es) | Un procedimiento para la preparacion de particulas de latex injertadas con polisacaridos | |
| CL2011000914A1 (es) | Vacuna combinada estable completamente liquida que comprende antigenos difterico, tetanico, pertusico acelular, de haemophilus influenzae, y de virus de poliomielitis en donde el antigeno se haemophilus influenzae no esta sustancialmente absorbido sobre ningun adyuvante; y proceso de fabricacion. | |
| MX2022010642A (es) | Vacunas contra coronavirus que comprenden un agonista de tlr9. | |
| DE602007004003D1 (de) | Verfahren zur fertigung von kegelrädern zwecks herstellung einer diffusen oberflächenstruktur | |
| WO2013160252A3 (en) | Dry silicone gels and their methods of making using thiol-ene chemistry | |
| CY1120430T1 (el) | Ανασυνδυασμενες cdv συνθεσεις και χρησεις αυτων | |
| WO2010044919A3 (en) | Smallpox dna vaccine and the antigens therein that elicit an immune response | |
| BRPI0818718B8 (pt) | processo de preparo de uma composição de vacina compreendendo antígeno e adjuvante na forma de látex inverso de homopolímero do ácido acrílico | |
| WO2007016340A3 (en) | Defective ribosomal products in blebs (dribbles) and methods of use to stimulate an immune response | |
| TW200624479A (en) | Film forming material and preparation of surface relief and optically anisotropic structures by irradiating a film of the said material |