ES2552518T3 - Derivados cíclicos de diaminopiridina como inhibidores de Syk - Google Patents
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- ES2552518T3 ES2552518T3 ES12808646.9T ES12808646T ES2552518T3 ES 2552518 T3 ES2552518 T3 ES 2552518T3 ES 12808646 T ES12808646 T ES 12808646T ES 2552518 T3 ES2552518 T3 ES 2552518T3
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| US201261601101P | 2012-02-21 | ||
| PCT/US2012/070252 WO2013126132A1 (en) | 2012-02-21 | 2012-12-18 | Cyclic diaminopyrimidine derivatives |
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| ES2552518T3 true ES2552518T3 (es) | 2015-11-30 |
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| EP3842442B1 (en) | 2016-12-22 | 2023-11-01 | Precision Pharmaceuticals, Inc. | Compositions and methods for inhibiting arginase activity |
| EP3942045A1 (en) | 2019-03-21 | 2022-01-26 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
| EP4054579A1 (en) | 2019-11-08 | 2022-09-14 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Methods for the treatment of cancers that have acquired resistance to kinase inhibitors |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| CN115515588A (zh) | 2020-02-14 | 2022-12-23 | 萨克生物研究学院 | 大环ulk1/2抑制剂 |
| CN116528877A (zh) * | 2020-10-05 | 2023-08-01 | 默克专利股份公司 | 用于治疗血液障碍和实体瘤的lmp7选择性抑制剂 |
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| AU2022248850A1 (en) | 2021-03-27 | 2023-11-09 | TRx Biosciences Limited | Compositions having improved bioavailability of therapeutics |
| US20250000859A1 (en) | 2021-08-25 | 2025-01-02 | Alesta Therapeutics BV | Use of gcn2 inhibitors in treating cancer |
| AU2023233811A1 (en) * | 2022-03-14 | 2024-09-19 | TRx Biosciences Limited | Compositions having improved bioavailability of therapeutics and uses thereof |
| WO2024017251A1 (zh) * | 2022-07-18 | 2024-01-25 | 江苏恒瑞医药股份有限公司 | 抑制并诱导egfr降解的大环类化合物、其制备方法及其在医药上的应用 |
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| CN1863780A (zh) * | 2002-08-14 | 2006-11-15 | 沃泰克斯药物股份有限公司 | 蛋白激酶抑制剂及其应用 |
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| AU2012370450A1 (en) | 2014-10-02 |
| JP6059260B2 (ja) | 2017-01-11 |
| US20150025066A1 (en) | 2015-01-22 |
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