ES2534358T3 - Inhibidores novedosos de MEK útiles en el tratamiento de enfermedades - Google Patents
Inhibidores novedosos de MEK útiles en el tratamiento de enfermedades Download PDFInfo
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- ES2534358T3 ES2534358T3 ES10824026.8T ES10824026T ES2534358T3 ES 2534358 T3 ES2534358 T3 ES 2534358T3 ES 10824026 T ES10824026 T ES 10824026T ES 2534358 T3 ES2534358 T3 ES 2534358T3
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- C07D291/00—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
- C07D291/08—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
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| US25093609P | 2009-10-13 | 2009-10-13 | |
| US250936P | 2009-10-13 | ||
| PCT/US2010/052514 WO2011047055A2 (en) | 2009-10-13 | 2010-10-13 | Novel mek inhibitors, useful in the treatment of diseases |
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| ES2534358T3 true ES2534358T3 (es) | 2015-04-21 |
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| ES10824026.8T Active ES2534358T3 (es) | 2009-10-13 | 2010-10-13 | Inhibidores novedosos de MEK útiles en el tratamiento de enfermedades |
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|---|---|
| US (1) | US9034861B2 (enExample) |
| EP (1) | EP2488507B1 (enExample) |
| JP (1) | JP5892612B2 (enExample) |
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| ES (1) | ES2534358T3 (enExample) |
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| US20190008859A1 (en) | 2015-08-21 | 2019-01-10 | Acerta Pharma B.V. | Therapeutic Combinations of a MEK Inhibitor and a BTK Inhibitor |
| WO2019038367A1 (en) | 2017-08-23 | 2019-02-28 | Cell Receptor AG | ASSOCIATION OF A MAPK / ERK INHIBITOR AND A GLYCOSAMINOGLYCAN FOR THE TREATMENT OF CANCER |
| KR20210142154A (ko) | 2019-03-21 | 2021-11-24 | 옹쎄오 | 암 치료를 위한 키나제 억제제와 조합된 dbait 분자 |
| CN114761006A (zh) | 2019-11-08 | 2022-07-15 | Inserm(法国国家健康医学研究院) | 对激酶抑制剂产生耐药性的癌症的治疗方法 |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| AU2021401282A1 (en) * | 2020-12-16 | 2023-07-13 | Abm Therapeutics Corporation | Kinase inhibitors and uses thereof |
| EP4346826A4 (en) | 2021-05-27 | 2025-04-30 | Mirati Therapeutics, Inc. | COMBINATION THERAPIES |
| WO2025073765A1 (en) | 2023-10-03 | 2025-04-10 | Institut National de la Santé et de la Recherche Médicale | Methods of prognosis and treatment of patients suffering from melanoma |
| WO2025147497A1 (en) * | 2024-01-05 | 2025-07-10 | Pasithea Therapeutics Corp. | Solid forms comprising (5r,6s)-10,11-difluoro-12-((2-fluoro-4-iodophenyl)amino)-5,6-dihydroxy-4,5,6,7-tetrahydro-1h-spiro[benzo[b][1,5,4]oxathiazecine-3,1'-cyclopropane] 2,2-dioxide, and compositions comprising and methods of using the same |
| TW202535345A (zh) * | 2024-01-05 | 2025-09-16 | 美商帕熙席亞醫療股份有限公司 | １０，１１－二氟－１２－（（２－氟－４－碘苯基）胺基）－５，６－二羥基－４，５，６，７－四氫－１ｈ－螺［苯并［ｂ］［１，５，４］氧雜噻西啶－３，１＇－環丙烷］ ２，２－二氧化物 立體異構物以及包含其之組合物及使用其之方法 |
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| AU2010306830A1 (en) | 2012-05-31 |
| JP5892612B2 (ja) | 2016-03-23 |
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| EP2488507B1 (en) | 2014-12-17 |
| WO2011047055A3 (en) | 2011-08-18 |
| KR20120094165A (ko) | 2012-08-23 |
| CN102666512B (zh) | 2014-11-26 |
| CN102666512A (zh) | 2012-09-12 |
| AU2010306830C1 (en) | 2015-05-28 |
| CA2814617C (en) | 2017-12-19 |
| BR112012008599A2 (pt) | 2019-09-24 |
| AU2010306830B2 (en) | 2014-11-06 |
| WO2011047055A2 (en) | 2011-04-21 |
| EP2488507A2 (en) | 2012-08-22 |
| US9034861B2 (en) | 2015-05-19 |
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