ES2531252T3 - Copolímeros aleatorios de metacrilatos y acrilatos - Google Patents

Copolímeros aleatorios de metacrilatos y acrilatos Download PDF

Info

Publication number
ES2531252T3
ES2531252T3 ES07796654T ES07796654T ES2531252T3 ES 2531252 T3 ES2531252 T3 ES 2531252T3 ES 07796654 T ES07796654 T ES 07796654T ES 07796654 T ES07796654 T ES 07796654T ES 2531252 T3 ES2531252 T3 ES 2531252T3
Authority
ES
Spain
Prior art keywords
methacrylate
weight ratio
present
total monomer
monomer weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07796654T
Other languages
English (en)
Inventor
Thierry Glauser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Cardiovascular Systems Inc
Original Assignee
Abbott Cardiovascular Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Cardiovascular Systems Inc filed Critical Abbott Cardiovascular Systems Inc
Application granted granted Critical
Publication of ES2531252T3 publication Critical patent/ES2531252T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D133/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Coating compositions based on derivatives of such polymers
    • C09D133/04—Homopolymers or copolymers of esters
    • C09D133/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/12—Esters of monohydric alcohols or phenols
    • C08F220/14—Methyl esters, e.g. methyl (meth)acrylate

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)

Abstract

Un dispositivo médico implantable que comprende un revestimiento que comprende: un copolímero aleatorio que comprende unidades derivadas de: (a) metacrilato de metilo, (b) metacrilato de metoxietilo, y (c) metacrilato de 2-hidroxietilo; donde el metacrilato de metilo está presente en un ratio de peso de los monómeros totales de hasta 0,7, donde el metacrilato de metoxietilo está presente en un ratio de peso de los monómeros totales de hasta 0,9, y donde el metacrilato de 2-hidroxiletilo está presente en un ratio de peso de los monómeros totales de hasta 0,2, y donde el revestimiento comprende además un fármaco hidrofílico y/o fármaco hidrofóbico, donde el revestimiento proporciona una liberación controlada del fármaco hidrofílico y/o el fármaco hidrofóbico.
ES07796654T 2006-07-06 2007-07-02 Copolímeros aleatorios de metacrilatos y acrilatos Active ES2531252T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/483,304 US20080008736A1 (en) 2006-07-06 2006-07-06 Random copolymers of methacrylates and acrylates
PCT/US2007/015367 WO2008005439A1 (en) 2006-07-06 2007-07-02 Random copolymers of methacrylates and acrylates

Publications (1)

Publication Number Publication Date
ES2531252T3 true ES2531252T3 (es) 2015-03-12

Family

ID=38656550

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07796654T Active ES2531252T3 (es) 2006-07-06 2007-07-02 Copolímeros aleatorios de metacrilatos y acrilatos

Country Status (5)

Country Link
US (1) US20080008736A1 (es)
EP (1) EP2046848B1 (es)
JP (1) JP2009542852A (es)
ES (1) ES2531252T3 (es)
WO (1) WO2008005439A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8236338B2 (en) 2004-07-13 2012-08-07 The University Of Tennessee Research Foundation Adhesive composition for carrying therapeutic agents as delivery vehicle on coatings applied to vascular grafts
US8293318B1 (en) 2006-08-29 2012-10-23 Abbott Cardiovascular Systems Inc. Methods for modulating the release rate of a drug-coated stent
US8475844B2 (en) * 2008-04-16 2013-07-02 Boston Scientific Scimed, Inc. Fluoropolymer-based medical implant coating compositions
US8765432B2 (en) * 2009-12-18 2014-07-01 Oligasis, Llc Targeted drug phosphorylcholine polymer conjugates
WO2014070792A1 (en) 2012-10-29 2014-05-08 Ariste Medical, Inc. Polymer coating compositions and coated products
CN102964505B (zh) * 2012-11-14 2015-03-18 阜阳师范学院 连续滴加与补加相结合制备高固体含量羟基丙烯酸树脂方法
PT3041513T (pt) 2013-09-08 2020-09-07 Kodiak Sciences Inc Conjugados de polímeros zwiteriónicos com fator viii
WO2015164524A1 (en) 2014-04-22 2015-10-29 Ariste Medical, Inc. Methods and processes for application of drug delivery polymeric coatings
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
WO2016061562A2 (en) 2014-10-17 2016-04-21 Kodiak Sciences Inc. Butyrylcholinesterase zwitterionic polymer conjugates
AU2016381964B2 (en) 2015-12-30 2024-02-15 Kodiak Sciences Inc. Antibodies and conjugates thereof
US10941374B2 (en) 2016-09-29 2021-03-09 Sumitomo Rubber Industries, Ltd. Medical analysis device and cell analysis method
JP6779483B2 (ja) 2016-09-29 2020-11-04 住友ゴム工業株式会社 医療用検査装置及び細胞検査方法
JP7299162B2 (ja) * 2017-05-12 2023-06-27 マイクロベンション インコーポレイテッド 医療機器を作成するための方法及び医療機器をコーティングする方法
JP7358030B2 (ja) * 2018-01-31 2023-10-10 住友ゴム工業株式会社 親水性基材
JP7109719B2 (ja) 2018-02-14 2022-08-01 住友ゴム工業株式会社 特定細胞捕捉方法
US11614440B2 (en) 2019-01-24 2023-03-28 Sumitomo Rubber Industries, Ltd. Specific cell fractionating and capturing methods
WO2021072265A1 (en) 2019-10-10 2021-04-15 Kodiak Sciences Inc. Methods of treating an eye disorder

Family Cites Families (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3780003A (en) * 1968-10-22 1973-12-18 Hydron Ltd Polymers of alkoxy and hydroxy alkyl acrylates or methacrylates
GB1278572A (en) * 1968-10-22 1972-06-21 Hydron Ltd Copolymers of acrylates and/or methacrylates
US3894980A (en) * 1973-04-30 1975-07-15 Rohm & Haas Thickener
US6387379B1 (en) * 1987-04-10 2002-05-14 University Of Florida Biofunctional surface modified ocular implants, surgical instruments, medical devices, prostheses, contact lenses and the like
US5019096A (en) * 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
US4931287A (en) * 1988-06-14 1990-06-05 University Of Utah Heterogeneous interpenetrating polymer networks for the controlled release of drugs
US4954587A (en) * 1988-07-05 1990-09-04 Ciba-Geigy Corporation Dimethylacrylamide-copolymer hydrogels with high oxygen permeability
JPH02151602A (ja) * 1988-12-05 1990-06-11 Asahi Chem Ind Co Ltd 低吸湿性共重合体
US5100582A (en) * 1989-12-28 1992-03-31 Nalco Chemical Company Water soluble polymer as water-in-oil demulsifier
US6248129B1 (en) * 1990-09-14 2001-06-19 Quanam Medical Corporation Expandable polymeric stent with memory and delivery apparatus and method
US5163952A (en) * 1990-09-14 1992-11-17 Michael Froix Expandable polymeric stent with memory and delivery apparatus and method
US5258020A (en) * 1990-09-14 1993-11-02 Michael Froix Method of using expandable polymeric stent with memory
DE69421188T2 (de) * 1993-08-23 2000-05-25 Procter & Gamble Thermoplastische und elastomere silikonpfropfcopolymere und diese enthaltende haar- und hautpflegemittel
WO1995024929A2 (en) * 1994-03-15 1995-09-21 Brown University Research Foundation Polymeric gene delivery system
EP1004293A3 (en) * 1994-10-12 2001-10-04 Focal, Inc. Targeted delivery via biodegradable polymers
US5637113A (en) * 1994-12-13 1997-06-10 Advanced Cardiovascular Systems, Inc. Polymer film for wrapping a stent structure
US5869127A (en) * 1995-02-22 1999-02-09 Boston Scientific Corporation Method of providing a substrate with a bio-active/biocompatible coating
US6179817B1 (en) * 1995-02-22 2001-01-30 Boston Scientific Corporation Hybrid coating for medical devices
US5674242A (en) * 1995-06-06 1997-10-07 Quanam Medical Corporation Endoprosthetic device with therapeutic compound
CA2178541C (en) * 1995-06-07 2009-11-24 Neal E. Fearnot Implantable medical device
US5609629A (en) * 1995-06-07 1997-03-11 Med Institute, Inc. Coated implantable medical device
US7550005B2 (en) * 1995-06-07 2009-06-23 Cook Incorporated Coated implantable medical device
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
US5723219A (en) * 1995-12-19 1998-03-03 Talison Research Plasma deposited film networks
US5932299A (en) * 1996-04-23 1999-08-03 Katoot; Mohammad W. Method for modifying the surface of an object
US5955096A (en) * 1996-06-25 1999-09-21 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients
US6530951B1 (en) * 1996-10-24 2003-03-11 Cook Incorporated Silver implantable medical device
US5997517A (en) * 1997-01-27 1999-12-07 Sts Biopolymers, Inc. Bonding layers for medical device surface coatings
US6159978A (en) * 1997-05-28 2000-12-12 Aventis Pharmaceuticals Product, Inc. Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases
US6245760B1 (en) * 1997-05-28 2001-06-12 Aventis Pharmaceuticals Products, Inc Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases
US6180632B1 (en) * 1997-05-28 2001-01-30 Aventis Pharmaceuticals Products Inc. Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases
WO1998057671A2 (en) * 1997-06-18 1998-12-23 Boston Scientific Corporation Polycarbonate-polyurethane dispersions for thrombo-resistant coatings
US6110483A (en) * 1997-06-23 2000-08-29 Sts Biopolymers, Inc. Adherent, flexible hydrogel and medicated coatings
US5834408A (en) * 1997-10-24 1998-11-10 Ethyl Corporation Pour point depressants via anionic polymerization of (meth)acrylic monomers
US6133391A (en) * 1998-03-17 2000-10-17 3M Innovative Properties Company Adhesive compositions and adhesive tapes comprising zwitterionic copolymers, and novel zwitterionic copolymers
US6258371B1 (en) * 1998-04-03 2001-07-10 Medtronic Inc Method for making biocompatible medical article
US20030040790A1 (en) * 1998-04-15 2003-02-27 Furst Joseph G. Stent coating
US20010029351A1 (en) * 1998-04-16 2001-10-11 Robert Falotico Drug combinations and delivery devices for the prevention and treatment of vascular disease
ATE466603T1 (de) * 1998-04-27 2010-05-15 Surmodics Inc Bioaktive wirkstoffe freisetzende beschichtungen
US6299604B1 (en) * 1998-08-20 2001-10-09 Cook Incorporated Coated implantable medical device
US6187024B1 (en) * 1998-11-10 2001-02-13 Target Therapeutics, Inc. Bioactive coating for vaso-occlusive devices
US6530950B1 (en) * 1999-01-12 2003-03-11 Quanam Medical Corporation Intraluminal stent having coaxial polymer member
JP4991030B2 (ja) * 1999-01-12 2012-08-01 ボストン サイエンティフィック サイムド，インコーポレイテッド 腔内ステント用の重合体組成物
US6143354A (en) * 1999-02-08 2000-11-07 Medtronic Inc. One-step method for attachment of biomolecules to substrate surfaces
US6368346B1 (en) * 1999-06-03 2002-04-09 American Medical Systems, Inc. Bioresorbable stent
US6790228B2 (en) * 1999-12-23 2004-09-14 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US6613432B2 (en) * 1999-12-22 2003-09-02 Biosurface Engineering Technologies, Inc. Plasma-deposited coatings, devices and methods
AU2599501A (en) * 1999-12-29 2001-07-09 Advanced Cardiovascular Systems Inc. Device and active component for inhibiting formation of thrombus-inflammatory cell matrix
US20020007214A1 (en) * 2000-05-19 2002-01-17 Robert Falotico Drug/drug delivery systems for the prevention and treatment of vascular disease
US20020007213A1 (en) * 2000-05-19 2002-01-17 Robert Falotico Drug/drug delivery systems for the prevention and treatment of vascular disease
US20020007215A1 (en) * 2000-05-19 2002-01-17 Robert Falotico Drug/drug delivery systems for the prevention and treatment of vascular disease
US20020005206A1 (en) * 2000-05-19 2002-01-17 Robert Falotico Antiproliferative drug and delivery device
US6776796B2 (en) * 2000-05-12 2004-08-17 Cordis Corportation Antiinflammatory drug and delivery device
US6306423B1 (en) * 2000-06-02 2001-10-23 Allergan Sales, Inc. Neurotoxin implant
US20020051730A1 (en) * 2000-09-29 2002-05-02 Stanko Bodnar Coated medical devices and sterilization thereof
US7261735B2 (en) * 2001-05-07 2007-08-28 Cordis Corporation Local drug delivery devices and methods for maintaining the drug coatings thereon
US20020111590A1 (en) * 2000-09-29 2002-08-15 Davila Luis A. Medical devices, drug coatings and methods for maintaining the drug coatings thereon
DK1383795T3 (da) * 2000-11-02 2007-05-29 Intervet Int Bv Rekombinant nucleoproteinmutant fra Newcastle disease-virus som markörvaccine
US7077859B2 (en) * 2000-12-22 2006-07-18 Avantec Vascular Corporation Apparatus and methods for variably controlled substance delivery from implanted prostheses
US20020082679A1 (en) * 2000-12-22 2002-06-27 Avantec Vascular Corporation Delivery or therapeutic capable agents
US6663662B2 (en) * 2000-12-28 2003-12-16 Advanced Cardiovascular Systems, Inc. Diffusion barrier layer for implantable devices
EP1463438A4 (en) * 2001-02-09 2008-01-23 Endoluminal Therapeutics Inc ENDOMURAL THERAPY
AU2002254158A1 (en) * 2001-03-08 2002-09-24 Volcano Therapeutics, Inc. Medical devices, compositions and methods for treating vulnerable plaque
US6780424B2 (en) * 2001-03-30 2004-08-24 Charles David Claude Controlled morphologies in polymer drug for release of drugs from polymer films
EP1383504A1 (en) * 2001-04-26 2004-01-28 Control Delivery Systems, Inc. Sustained release drug delivery system containing codrugs
US6703466B1 (en) * 2001-06-18 2004-03-09 Alcon, Inc. Foldable intraocular lens optics having a glassy surface
US7247313B2 (en) * 2001-06-27 2007-07-24 Advanced Cardiovascular Systems, Inc. Polyacrylates coatings for implantable medical devices
US6585755B2 (en) * 2001-06-29 2003-07-01 Advanced Cardiovascular Polymeric stent suitable for imaging by MRI and fluoroscopy
JP2005504813A (ja) * 2001-09-24 2005-02-17 メドトロニック・エイヴイイー・インコーポレーテッド 合理的薬剤療法デバイス及び方法
US7195640B2 (en) * 2001-09-25 2007-03-27 Cordis Corporation Coated medical devices for the treatment of vulnerable plaque
US20030065377A1 (en) * 2001-09-28 2003-04-03 Davila Luis A. Coated medical devices
US6939376B2 (en) * 2001-11-05 2005-09-06 Sun Biomedical, Ltd. Drug-delivery endovascular stent and method for treating restenosis
US7005137B1 (en) * 2002-06-21 2006-02-28 Advanceed Cardiovascular Systems, Inc. Coating for implantable medical devices
JP4219154B2 (ja) * 2002-11-15 2009-02-04 テルモ株式会社 血液適合性高分子を用いた医療用器具
US7094256B1 (en) * 2002-12-16 2006-08-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical device containing polycationic peptides
US7169404B2 (en) * 2003-07-30 2007-01-30 Advanced Cardiovasular Systems, Inc. Biologically absorbable coatings for implantable devices and methods for fabricating the same
US7261946B2 (en) * 2003-11-14 2007-08-28 Advanced Cardiovascular Systems, Inc. Block copolymers of acrylates and methacrylates with fluoroalkenes
US9114198B2 (en) * 2003-11-19 2015-08-25 Advanced Cardiovascular Systems, Inc. Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same
US7435788B2 (en) * 2003-12-19 2008-10-14 Advanced Cardiovascular Systems, Inc. Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents
US8309112B2 (en) * 2003-12-24 2012-11-13 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices comprising hydrophilic substances and methods for fabricating the same
WO2005089855A1 (en) * 2004-03-19 2005-09-29 Abbott Laboratories Multiple drug delivery from a balloon and a prosthesis
US7244443B2 (en) * 2004-08-31 2007-07-17 Advanced Cardiovascular Systems, Inc. Polymers of fluorinated monomers and hydrophilic monomers
US8110211B2 (en) * 2004-09-22 2012-02-07 Advanced Cardiovascular Systems, Inc. Medicated coatings for implantable medical devices including polyacrylates
US9011831B2 (en) * 2004-09-30 2015-04-21 Advanced Cardiovascular Systems, Inc. Methacrylate copolymers for medical devices
US8388677B2 (en) * 2004-10-29 2013-03-05 Boston Scientific Scimed, Inc. Anti-thrombogenic and anti-restenotic vascular medical devices
EP1655354B1 (en) * 2004-11-09 2013-10-23 JSR Corporation A biological substance absorption preventing coating composition, an article coated therewith and a method of using the same
JP5177340B2 (ja) * 2004-11-09 2013-04-03 Ｊｓｒ株式会社 生体関連物質用物品およびその製造方法、ならびに生体関連物質吸着防止用コーティング組成物およびその使用方法
JP2009532563A (ja) * 2006-04-06 2009-09-10 シミックス テクノロジーズ， インコーポレイテッド 親水性活性を有する耐水性皮膜形成用組成物

Also Published As

Publication number Publication date
EP2046848A1 (en) 2009-04-15
WO2008005439A1 (en) 2008-01-10
JP2009542852A (ja) 2009-12-03
EP2046848B1 (en) 2014-11-26
US20080008736A1 (en) 2008-01-10

Similar Documents

Publication Publication Date Title
ES2531252T3 (es) Copolímeros aleatorios de metacrilatos y acrilatos
AR097045A2 (es) Sistema terapéutico transdérmico
ES2483996T3 (es) Sistemas y métodos de tratamiento de los huesos
AR111679A2 (es) Formulación farmacéutica de liberación controlada, procesos, usos, método
WO2007006353A3 (de) Verwendung eines teilneutralisierten, anionischen (meth) acrylat-copolymers als uberzug fur die herstellung einer arzneiform mit einer wirkstofffreisetzung bei erniedrigten ph-werten
CY1120879T1 (el) Πολλαπλου συστατικου βιοδραστικος ενδοκολπικος δακτυλιος
BRPI0315740B8 (pt) formas de dosagem com multicamadas que contêm substâncias ativas e que compreendem um núcleo neutro e um revestimento interno e externo composto por copolímeros de metacrilato e monômeros de metacrilato
WO2006036558A3 (en) Medicated coatings for implantable medical devices including polyacrylates
AR085730A1 (es) Articulo absorbente
CL2008001991A1 (es) Uso de homo y copolimeros que comprenden al menos 10% en peso de un monomero seleccionado entre acido acrilico y metacrilico y hasta 90% de uno o mas monomeros no ionicos, donde la suma de ambos es de al menos el 70% de los monomeros; composicion y preparacion del principio activo; dispersion acuosa y su preparacion.
WO2010011585A3 (en) Ophthalmic device having therapeutic agent delivery capability and method of forming same
AR050190A1 (es) Composiciones para el cuidado oral con polimeros formadores de peliculas
SI1355633T1 (en) NEW FILM COATING containing an ethyl acrylate/methyl methacrylate copolymer and polyvinyl acetate
AR047540A1 (es) Particulados
BR112017026746A2 (pt) composições de liberação de fármacos implantáveis e métodos de uso dos mesmos
UY30883A1 (es) Tapones punctales y metodos de liberacion de agentes terapeuticos
PE20141115A1 (es) Comprimido de desintegracion oral
TW200801147A (en) High-strength adhesive polymer gel and adhesive tape
MX356579B (es) Composicion farmaceutica o nutraceutica de resistencia gastrica con resistencia contra la influenza de etanol.
MX2009003439A (es) Aplicador para un dispositivo para la incontinencia urinaria.
BR112020019629A8 (pt) dispersantes agroquímicos de polímero
RU2007144068A (ru) Состав аэрозольного лака для волос
ATE471954T1 (de) Teilneutralisiertes anionisches (meth)acrylat- copolymer
UA93530C2 (ru) Композиция c пролонгированным высвобождением активного вещества, способ ee получения и применения
ATE409464T1 (de) Mehrschichtige arzneiform