ES2527665T3 - Instrumento de diagnóstico y proceso de flujo - Google Patents

Instrumento de diagnóstico y proceso de flujo Download PDF

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Publication number
ES2527665T3
ES2527665T3 ES11778379.5T ES11778379T ES2527665T3 ES 2527665 T3 ES2527665 T3 ES 2527665T3 ES 11778379 T ES11778379 T ES 11778379T ES 2527665 T3 ES2527665 T3 ES 2527665T3
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ES
Spain
Prior art keywords
probe
samples
holder
tube
monoaxial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11778379.5T
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English (en)
Inventor
Richard A. Thomas
Michael W. BROCHU Sr.
Michael L. Brochu
Ernest R. Thomas
Michael A. Thomas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Biomedical LLC
Original Assignee
Beckman Coulter Biomedical LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Biomedical LLC filed Critical Beckman Coulter Biomedical LLC
Application granted granted Critical
Publication of ES2527665T3 publication Critical patent/ES2527665T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G01N35/00613—Quality control
    • G01N35/00623—Quality control of instruments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/0092—Scheduling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Quality & Reliability (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Sustainable Development (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Un instrumento de diagnóstico de análisis celular para preparar y analizar muestras, comprendiendo el instrumento de diagnóstico: un portasondas (22) configurado para desplazarse a lo largo de una guía monoaxial (24), una sonda (26) acoplada al portasondas (22) para aspirar y depositar muestras y reactivos, una multitud de cartuchos (14) de tubos, estando cada cartucho (14) de tubos configurado para contener en su interior una multitud de tubos (16) que contienen muestras, una zona (20) de contención que tiene tubos o pozos vacíos para el tratamiento de las muestras, y un citómetro de flujo acoplado a la zona (20) de contención para analizar las muestras tratadas, en el que el portasondas (22) está configurado para: a. colocar la sonda (26) para tomar muestras de los tubos (16) de un cartucho (14) de tubos cuando el portasondas (22) se desplaza a una posición A a lo largo de la guía monoaxial (24); b. colocar la sonda (26) para aspirar reactivos cuando el portasondas (22) se desplaza a una posición C a lo largo de la guía monoaxial (24); y c. colocar la sonda (26) para depositar las muestras que se han tomado y/o los reactivos aspirados en el tubo o pozo de la zona (20) de contención cuando el portasondas (22) se desplaza a una posición B a lo largo de la guía monoaxial (24).

Description

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Claims (1)

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ES11778379.5T 2010-05-05 2011-05-05 Instrumento de diagnóstico y proceso de flujo Active ES2527665T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US33178210P 2010-05-05 2010-05-05
US33178710P 2010-05-05 2010-05-05
US331787P 2010-05-05
US331782P 2010-05-05
PCT/US2011/035417 WO2011140387A1 (en) 2010-05-05 2011-05-05 Diagnostic instrument and flow process

Publications (1)

Publication Number Publication Date
ES2527665T3 true ES2527665T3 (es) 2015-01-28

Family

ID=44904088

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11778379.5T Active ES2527665T3 (es) 2010-05-05 2011-05-05 Instrumento de diagnóstico y proceso de flujo

Country Status (9)

Country Link
US (1) US9568428B2 (es)
EP (1) EP2566974B1 (es)
JP (2) JP2013525816A (es)
KR (1) KR101912952B1 (es)
CN (1) CN102947462B (es)
BR (1) BR112012029520B1 (es)
ES (1) ES2527665T3 (es)
RU (1) RU2579971C2 (es)
WO (1) WO2011140387A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2929040T3 (es) * 2011-10-28 2022-11-24 Aeneas Gmbh & Co Kg Dispositivo y procedimiento para detectar sustancias presentes en muestras biológicas o químicas
US10739245B2 (en) * 2016-04-26 2020-08-11 Cytek Biosciences, Inc. Compact multi-color flow cytometer
IT201600069410A1 (it) * 2016-07-04 2018-01-04 Alifax Srl Apparato integrato per analisi diagnostiche
JP7532231B2 (ja) * 2020-11-30 2024-08-13 シスメックス株式会社 検出方法および検出装置
CN112834412A (zh) * 2021-03-04 2021-05-25 常州必达科生物科技有限公司 流式样本预处理系统及流式细胞仪
CN118362748B (zh) * 2024-06-17 2024-09-10 深圳市海拓华擎生物科技有限公司 一种全自动血液细胞分析仪

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JPH05180831A (ja) * 1991-08-30 1993-07-23 Omron Corp 細胞分析装置
CA2161224C (en) * 1994-02-25 1999-02-02 Gerald Brinker Dissolution testing apparatus
US6586193B2 (en) * 1996-04-25 2003-07-01 Genicon Sciences Corporation Analyte assay using particulate labels
DE69804239T2 (de) * 1997-11-04 2002-10-31 Monogen, Inc. Verfahren und apparat zur durchmischung und abscheidung von partikel-material aus einer flüssigen probe
US6830935B1 (en) * 1998-07-07 2004-12-14 Lamina, Inc. Method for mixing and processing specimen samples
JP4580074B2 (ja) * 2000-08-09 2010-11-10 株式会社堀場製作所 血液測定装置および全血免疫測定装置ならびにこれらの装置に用いられるサンプリングプローブ
DE60307825T2 (de) * 2002-05-17 2007-03-01 Gen-Probe Inc., San Diego Probenträger mit feststelleinrichtung und zugehörige tropfschirmvorrichtung
JP3863087B2 (ja) * 2002-10-25 2006-12-27 シスメックス株式会社 試料分析装置およびその装置に使用されるピペット洗浄用希釈液
FR2859285B1 (fr) * 2003-08-26 2007-08-10 Abx Sa Analyseur hematologique sur sang total avec dispositif d'agitation
JP4030500B2 (ja) 2003-12-19 2008-01-09 株式会社ノダ 床暖房装置
WO2005093433A1 (en) 2004-03-05 2005-10-06 Beckman Coulter, Inc. Magnetically attractive specimen-container rack for automated clinical instrument
CN102759466A (zh) 2004-09-15 2012-10-31 英特基因有限公司 微流体装置
US7580120B2 (en) * 2005-04-07 2009-08-25 Sysmex Corporation Blood analyzer, sample analyzer, and flow cytometer
JP4756948B2 (ja) * 2005-08-08 2011-08-24 ベイバイオサイエンス株式会社 フローサイトメータおよびフローサイトメトリ方法
JP4768409B2 (ja) * 2005-11-15 2011-09-07 シスメックス株式会社 試料分析装置、試料分析本体装置、及び試料容器供給装置
JP5198094B2 (ja) 2008-03-07 2013-05-15 シスメックス株式会社 分析装置
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KR20130098169A (ko) * 2010-05-05 2013-09-04 베크만 쿨터 바이오메디컬, 엘엘씨 진단 시스템 및 구성요소

Also Published As

Publication number Publication date
US20130143309A1 (en) 2013-06-06
JP6180585B2 (ja) 2017-08-16
US9568428B2 (en) 2017-02-14
RU2012152092A (ru) 2014-06-10
RU2579971C2 (ru) 2016-04-10
CN102947462A (zh) 2013-02-27
WO2011140387A1 (en) 2011-11-10
EP2566974A4 (en) 2013-09-04
BR112012029520B1 (pt) 2021-07-06
JP2013525816A (ja) 2013-06-20
BR112012029520A2 (pt) 2016-12-06
JP2016173372A (ja) 2016-09-29
EP2566974B1 (en) 2014-11-05
CN102947462B (zh) 2014-12-17
KR20130107202A (ko) 2013-10-01
EP2566974A1 (en) 2013-03-13
KR101912952B1 (ko) 2018-10-29

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