ES2527306T3 - Métodos de espectrometría de masas para la detección simultánea de actividad de enzimas metabólicas y niveles de metabolitos - Google Patents
Métodos de espectrometría de masas para la detección simultánea de actividad de enzimas metabólicas y niveles de metabolitos Download PDFInfo
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- ES2527306T3 ES2527306T3 ES04782672.2T ES04782672T ES2527306T3 ES 2527306 T3 ES2527306 T3 ES 2527306T3 ES 04782672 T ES04782672 T ES 04782672T ES 2527306 T3 ES2527306 T3 ES 2527306T3
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- G—PHYSICS
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- G01N2800/00—Detection or diagnosis of diseases
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| US652732 | 2003-08-29 | ||
| PCT/US2004/028238 WO2005021779A1 (en) | 2003-08-29 | 2004-08-30 | Mass spectrometry methods for simultaneous detection of metabolic enzyme activity and metabolite levels |
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| US7485435B2 (en) * | 2004-08-30 | 2009-02-03 | Perkinelmer Las, Inc. | Simultaneous detection of metabolic enzyme activity and metabolite levels |
| GB2413695B (en) * | 2004-04-30 | 2009-01-21 | Micromass Ltd | Mass spectrometer |
| GB0409676D0 (en) * | 2004-04-30 | 2004-06-02 | Micromass Ltd | Mass spectrometer |
| EP1724587B1 (en) * | 2005-05-20 | 2009-09-30 | GermedIQ Forschungs- und Entwicklungsgesellschaft mbH | Method for determination of cardiovascular risk factors in dried blood |
| JP5005955B2 (ja) * | 2006-05-24 | 2012-08-22 | 田辺三菱製薬株式会社 | 被験物質の脂質代謝異常症誘発可能性を予測する方法 |
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| US7923257B2 (en) * | 2007-05-04 | 2011-04-12 | Perkinelmer Health Sciences, Inc. | Detecting isomers using differential derivatization mass spectrometry |
| EP3543691A1 (en) * | 2007-06-29 | 2019-09-25 | Quest Diagnostics Investments Incorporated | Analysis of amino acids in body fluid by liquid chromatography-mass spectrometry |
| EP2229452B1 (en) * | 2007-12-05 | 2015-07-29 | King's College London | Method for aiding the diagnosis of a disorder |
| FI20090100A0 (fi) * | 2009-03-16 | 2009-03-16 | Wallac Oy | Biotinidaasimääritys |
| US9997341B2 (en) | 2014-03-10 | 2018-06-12 | Micromass Uk Limited | Unknown identification using collision cross section |
| JP6055957B2 (ja) | 2014-03-31 | 2016-12-27 | 積水メディカル株式会社 | アシルカルニチン組成物 |
| JP6101385B2 (ja) * | 2015-04-24 | 2017-03-22 | 株式会社 資生堂 | 分析方法 |
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| CN109416926A (zh) * | 2016-04-11 | 2019-03-01 | 迪森德克斯公司 | 质谱数据分析工作流程 |
| WO2018174858A1 (en) * | 2017-03-21 | 2018-09-27 | Mprobe Inc. | Clinical method for the population screening of adult metabolic disorder associated with chronic human disease |
| CN111272888A (zh) * | 2020-01-10 | 2020-06-12 | 山东英盛生物技术有限公司 | 一种新生儿血片中氨基酸及肉碱筛查预处理方法 |
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| JP3345401B2 (ja) * | 1998-08-25 | 2002-11-18 | ユニバーシティ オブ ワシントン | 複合した混合物中のタンパク質またはタンパク質機能の迅速定量分析 |
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| US6258605B1 (en) * | 1999-03-26 | 2001-07-10 | Neo Gen Screening, Inc. | Clinical method for the genetic screening of newborns using tandem mass spectrometry |
| US6455321B1 (en) * | 1999-01-30 | 2002-09-24 | Neo Gen Screening, Inc. | Method for interpreting tandem mass spectrometry data for clinical diagnosis |
| EP1113269B1 (en) | 1999-12-29 | 2006-10-18 | PerkinElmer Life Sciences, Inc. | Test tray, kit and methods for screening body fluids of newborns by tandem mass spectrometry |
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| US20120122131A1 (en) | 2012-05-17 |
| WO2005021779A1 (en) | 2005-03-10 |
| AU2004269410B2 (en) | 2008-12-18 |
| US20090111137A1 (en) | 2009-04-30 |
| CA2537034A1 (en) | 2005-03-10 |
| CA2537034C (en) | 2015-11-17 |
| EP1664325A4 (en) | 2008-04-30 |
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