ES2523030T3 - Un conjugado del G-CSF modificado por un polímero hidrosoluble - Google Patents
Un conjugado del G-CSF modificado por un polímero hidrosoluble Download PDFInfo
- Publication number
- ES2523030T3 ES2523030T3 ES08706693.2T ES08706693T ES2523030T3 ES 2523030 T3 ES2523030 T3 ES 2523030T3 ES 08706693 T ES08706693 T ES 08706693T ES 2523030 T3 ES2523030 T3 ES 2523030T3
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
- C07K17/08—Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
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- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Transplantation (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2008/070320 WO2009103199A1 (zh) | 2008-02-18 | 2008-02-18 | 水溶性聚合物修饰的g-csf偶联物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2523030T3 true ES2523030T3 (es) | 2014-11-20 |
Family
ID=40985048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES08706693.2T Active ES2523030T3 (es) | 2008-02-18 | 2008-02-18 | Un conjugado del G-CSF modificado por un polímero hidrosoluble |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8629104B2 (https=) |
| EP (1) | EP2248832B1 (https=) |
| JP (1) | JP5225393B2 (https=) |
| ES (1) | ES2523030T3 (https=) |
| WO (1) | WO2009103199A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2675035T3 (es) | 2011-10-14 | 2018-07-05 | Amgen, Inc | Inyector y método de ensamblaje |
| IL292270B2 (en) | 2013-03-22 | 2024-04-01 | Amgen Inc | Injector and method of assembly |
| MX373358B (es) | 2013-10-24 | 2020-07-06 | Amgen Inc | Inyector y método de montaje. |
| US11732016B2 (en) * | 2017-12-27 | 2023-08-22 | Council Of Scientific & Industrial Research | Polypeptide exhibiting granulocyte-colony stimulating factor activity |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5362853A (en) | 1986-12-23 | 1994-11-08 | Kyowa Hakko Kogyo Co., Ltd. | Polypeptide derivatives of human granulocyte colony stimulating factor |
| US5214132A (en) | 1986-12-23 | 1993-05-25 | Kyowa Hakko Kogyo Co., Ltd. | Polypeptide derivatives of human granulocyte colony stimulating factor |
| US4904584A (en) | 1987-12-23 | 1990-02-27 | Genetics Institute, Inc. | Site-specific homogeneous modification of polypeptides |
| CA1340810C (en) | 1988-03-31 | 1999-11-02 | Motoo Yamasaki | Polypeptide derivatives of human granulocyte colony stimulating factor |
| EP0401384B1 (en) | 1988-12-22 | 1996-03-13 | Kirin-Amgen, Inc. | Chemically modified granulocyte colony stimulating factor |
| US5581476A (en) | 1993-01-28 | 1996-12-03 | Amgen Inc. | Computer-based methods and articles of manufacture for preparing G-CSF analogs |
| US5824784A (en) | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
| JP2002540065A (ja) | 1999-01-29 | 2002-11-26 | アムジェン インコーポレーテッド | Ｇｃｓｆコンジュゲート |
| SK11672002A3 (sk) | 2000-01-10 | 2002-12-03 | Maxygen Holdings Ltd. | Polypeptidový konjugát, spôsob jeho výroby, farmaceutický prostriedok s jeho obsahom a jeho použitie |
| KR101237884B1 (ko) | 2003-12-03 | 2013-02-27 | 바이오제너릭스 에이지 | 글리코 peg화 과립구 콜로니 자극인자 |
| WO2006063055A2 (en) * | 2004-12-06 | 2006-06-15 | Bolder Biotechnology, Inc. | Enzyme conjugates for use as detoxifying agents |
| ATE494012T1 (de) * | 2004-12-21 | 2011-01-15 | Nektar Therapeutics | Stabilisierte polymer-thiol-reagenzien |
| KR100694994B1 (ko) * | 2005-06-13 | 2007-03-14 | 씨제이 주식회사 | 사람 과립구 콜로니 형성인자 동종체 |
| MX2008001706A (es) | 2005-08-04 | 2008-04-07 | Nektar Therapeutics Al Corp | Conjugados de una porcion g-csf y un polimero. |
| CN101172161B (zh) * | 2006-10-30 | 2010-04-21 | 江苏恒瑞医药股份有限公司 | 水溶性聚合物修饰的g-csf偶联物 |
-
2008
- 2008-02-18 WO PCT/CN2008/070320 patent/WO2009103199A1/zh not_active Ceased
- 2008-02-18 US US12/918,280 patent/US8629104B2/en not_active Expired - Fee Related
- 2008-02-18 ES ES08706693.2T patent/ES2523030T3/es active Active
- 2008-02-18 EP EP08706693.2A patent/EP2248832B1/en not_active Not-in-force
- 2008-02-18 JP JP2010546197A patent/JP5225393B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2248832B1 (en) | 2014-09-03 |
| JP2011512336A (ja) | 2011-04-21 |
| WO2009103199A1 (zh) | 2009-08-27 |
| US20130109623A1 (en) | 2013-05-02 |
| JP5225393B2 (ja) | 2013-07-03 |
| EP2248832A4 (en) | 2012-01-04 |
| US8629104B2 (en) | 2014-01-14 |
| EP2248832A1 (en) | 2010-11-10 |
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