ES2484315T3 - Tratamiento de la pérdida del sentido del tacto con derivados de saxitoxina - Google Patents
Tratamiento de la pérdida del sentido del tacto con derivados de saxitoxina Download PDFInfo
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- ES2484315T3 ES2484315T3 ES11707610.9T ES11707610T ES2484315T3 ES 2484315 T3 ES2484315 T3 ES 2484315T3 ES 11707610 T ES11707610 T ES 11707610T ES 2484315 T3 ES2484315 T3 ES 2484315T3
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- treatment
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Classifications
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US312903P | 2001-08-16 | ||
| EP10153234 | 2010-02-10 | ||
| EP10153234 | 2010-02-10 | ||
| US31290310P | 2010-03-11 | 2010-03-11 | |
| PCT/EP2011/051992 WO2011098539A1 (en) | 2010-02-10 | 2011-02-10 | Treatment of loss of sense of touch with saxitoxin derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2484315T3 true ES2484315T3 (es) | 2014-08-11 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES11707610.9T Active ES2484315T3 (es) | 2010-02-10 | 2011-02-10 | Tratamiento de la pérdida del sentido del tacto con derivados de saxitoxina |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9107925B2 (enExample) |
| EP (1) | EP2533785B1 (enExample) |
| JP (2) | JP6112867B2 (enExample) |
| CN (1) | CN102811722A (enExample) |
| ES (1) | ES2484315T3 (enExample) |
| WO (1) | WO2011098539A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8173666B2 (en) | 2007-03-12 | 2012-05-08 | Nektar Therapeutics | Oligomer-opioid agonist conjugates |
| US10512644B2 (en) | 2007-03-12 | 2019-12-24 | Inheris Pharmaceuticals, Inc. | Oligomer-opioid agonist conjugates |
| JP6112867B2 (ja) * | 2010-02-10 | 2017-04-12 | ファイトトックス リミテッドＰｈｙｔｏｔｏｘ Ｌｉｍｉｔｅｄ | サキシトキシン誘導体での触覚の喪失の処置 |
| EP2638908A1 (en) * | 2012-03-16 | 2013-09-18 | Phytotox SpA | Paralytic Shellfish Poison |
| KR102787826B1 (ko) | 2013-03-15 | 2025-03-31 | 더 칠드런스 메디칼 센터 코포레이션 | 지속성 국소 마취용 네오삭시톡신 조합 제형 |
| CA2944549A1 (en) * | 2014-04-09 | 2015-10-15 | Siteone Therapeutics, Inc. | 10',11'-modified saxitoxin useful for the treatment of pain |
| AU2016329201A1 (en) | 2015-09-30 | 2018-04-26 | Siteone Therapeutics, Inc. | 11,13-modified saxitoxins for the treatment of pain |
| GB201602576D0 (en) | 2016-02-12 | 2016-03-30 | Bergen Teknologioverforing As | Process |
| JP2020515611A (ja) * | 2017-03-29 | 2020-05-28 | サイトワン セラピューティクス， インコーポレイテッド | 疼痛の処置のための１１，１３−修飾サキシトキシン |
| CA3058214A1 (en) | 2017-03-29 | 2018-10-04 | The Board Of Trustees Of The Leland Stanford Junior University | 11,13-modified saxitoxins for the treatment of pain |
| EP3860714B1 (en) | 2018-10-03 | 2023-09-06 | Siteone Therapeutics, Inc. | 11,13-modified saxitoxins for the treatment of pain |
| EP4196482B1 (en) * | 2020-08-14 | 2025-10-01 | SiteOne Therapeutics, Inc. | Non-hydrated ketone inhibitors of nav1.7 for the treatment of pain |
| WO2022112887A1 (en) * | 2020-11-25 | 2022-06-02 | Algenis | Method of treating acute nociceptive pain in mammals |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1284536C (zh) | 2000-09-18 | 2006-11-15 | 威克斯医药有限公司 | 河豚毒素或蛤蚌毒素及其类似物在制备用于全身镇痛的镇痛药中的应用 |
| MXPA04004543A (es) * | 2001-11-15 | 2005-03-31 | Micro Algae Corp | Composiciones farmaceuticas que contienen 3,4-propinoperhidropurinas y sus usos para el bloqueo de la transmision neuronal. |
| EP1796676B1 (en) * | 2004-05-07 | 2016-03-09 | Phytotox Limited | Transdermal administration of phycotoxins |
| BRPI0510759A (pt) * | 2004-05-07 | 2007-11-20 | Phytotox Ltd | método de facilitar a cura de um ferimento |
| AU2005287511A1 (en) | 2004-09-21 | 2006-03-30 | Wex Medical Limited | Tetrodotoxin and its derivatives for the treatment of central-nervously derived neuropathic pain |
| KR20070092698A (ko) | 2004-09-22 | 2007-09-13 | 라보라토리오스 델 드라. 에스테브.에스.에이. | 말초 신경적으로 유발된 신경병증성 통증을 치료하기 위한테트로도톡신 및 그것의 유도체 |
| WO2007110221A1 (en) | 2006-03-27 | 2007-10-04 | Wex Pharmaceuticals Inc. | Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy |
| JP6112867B2 (ja) * | 2010-02-10 | 2017-04-12 | ファイトトックス リミテッドＰｈｙｔｏｔｏｘ Ｌｉｍｉｔｅｄ | サキシトキシン誘導体での触覚の喪失の処置 |
-
2011
- 2011-02-10 JP JP2012552401A patent/JP6112867B2/ja not_active Expired - Fee Related
- 2011-02-10 US US13/575,229 patent/US9107925B2/en active Active
- 2011-02-10 ES ES11707610.9T patent/ES2484315T3/es active Active
- 2011-02-10 CN CN2011800149701A patent/CN102811722A/zh active Pending
- 2011-02-10 EP EP11707610.9A patent/EP2533785B1/en not_active Not-in-force
- 2011-02-10 WO PCT/EP2011/051992 patent/WO2011098539A1/en not_active Ceased
-
2015
- 2015-07-08 US US14/794,428 patent/US20160000793A1/en not_active Abandoned
-
2016
- 2016-11-07 JP JP2016217143A patent/JP2017081920A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20160000793A1 (en) | 2016-01-07 |
| JP2017081920A (ja) | 2017-05-18 |
| WO2011098539A1 (en) | 2011-08-18 |
| US9107925B2 (en) | 2015-08-18 |
| EP2533785B1 (en) | 2014-04-23 |
| US20130039976A1 (en) | 2013-02-14 |
| EP2533785A1 (en) | 2012-12-19 |
| CN102811722A (zh) | 2012-12-05 |
| JP6112867B2 (ja) | 2017-04-12 |
| JP2013519653A (ja) | 2013-05-30 |
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