ES2470333T3 - Composiciones y métodos para aumentar los niveles de plaquetas de la sangre en humanos - Google Patents
Composiciones y métodos para aumentar los niveles de plaquetas de la sangre en humanos Download PDFInfo
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- ES2470333T3 ES2470333T3 ES11190964.4T ES11190964T ES2470333T3 ES 2470333 T3 ES2470333 T3 ES 2470333T3 ES 11190964 T ES11190964 T ES 11190964T ES 2470333 T3 ES2470333 T3 ES 2470333T3
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- 230000000144 pharmacologic effect Effects 0.000 description 1
- 229960003742 phenol Drugs 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 229960000540 polacrilin potassium Drugs 0.000 description 1
- 229960000502 poloxamer Drugs 0.000 description 1
- 229920001983 poloxamer Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 description 1
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 description 1
- 239000004302 potassium sorbate Substances 0.000 description 1
- 235000010241 potassium sorbate Nutrition 0.000 description 1
- 229940069338 potassium sorbate Drugs 0.000 description 1
- WVWZXTJUCNEUAE-UHFFFAOYSA-M potassium;1,2-bis(ethenyl)benzene;2-methylprop-2-enoate Chemical compound [K+].CC(=C)C([O-])=O.C=CC1=CC=CC=C1C=C WVWZXTJUCNEUAE-UHFFFAOYSA-M 0.000 description 1
- 229920001592 potato starch Polymers 0.000 description 1
- 229920003124 powdered cellulose Polymers 0.000 description 1
- 235000019814 powdered cellulose Nutrition 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000000651 prodrug Substances 0.000 description 1
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- 210000000512 proximal kidney tubule Anatomy 0.000 description 1
- 239000001327 prunus amygdalus amara l. extract Substances 0.000 description 1
- 230000001698 pyrogenic effect Effects 0.000 description 1
- 231100001028 renal lesion Toxicity 0.000 description 1
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- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 235000019204 saccharin Nutrition 0.000 description 1
- 229940081974 saccharin Drugs 0.000 description 1
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- 238000007493 shaping process Methods 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 229940083037 simethicone Drugs 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 229960003885 sodium benzoate Drugs 0.000 description 1
- 229940001607 sodium bisulfite Drugs 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 229960003339 sodium phosphate Drugs 0.000 description 1
- 235000011008 sodium phosphates Nutrition 0.000 description 1
- JXKPEJDQGNYQSM-UHFFFAOYSA-M sodium propionate Chemical compound [Na+].CCC([O-])=O JXKPEJDQGNYQSM-UHFFFAOYSA-M 0.000 description 1
- 239000004324 sodium propionate Substances 0.000 description 1
- 235000010334 sodium propionate Nutrition 0.000 description 1
- 229960003212 sodium propionate Drugs 0.000 description 1
- 229920003109 sodium starch glycolate Polymers 0.000 description 1
- 239000008109 sodium starch glycolate Substances 0.000 description 1
- 229940079832 sodium starch glycolate Drugs 0.000 description 1
- 239000012439 solid excipient Substances 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
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- 238000005507 spraying Methods 0.000 description 1
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- 239000000126 substance Substances 0.000 description 1
- 235000019408 sucralose Nutrition 0.000 description 1
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
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- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
- 229940033663 thimerosal Drugs 0.000 description 1
- 230000035921 thrombopoiesis Effects 0.000 description 1
- 230000001361 thrombopoietic effect Effects 0.000 description 1
- 239000001789 thuja occidentalis l. leaf oil Substances 0.000 description 1
- 239000010678 thyme oil Substances 0.000 description 1
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- 235000010215 titanium dioxide Nutrition 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 229960002622 triacetin Drugs 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 210000003954 umbilical cord Anatomy 0.000 description 1
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- 235000019163 vitamin B12 Nutrition 0.000 description 1
- 239000011715 vitamin B12 Substances 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83633406P | 2006-08-08 | 2006-08-08 | |
| US836334P | 2006-08-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2470333T3 true ES2470333T3 (es) | 2014-06-23 |
Family
ID=39082656
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES11190964.4T Active ES2470333T3 (es) | 2006-08-08 | 2007-08-08 | Composiciones y métodos para aumentar los niveles de plaquetas de la sangre en humanos |
| ES07811274.5T Active ES2452032T3 (es) | 2006-08-08 | 2007-08-08 | Composiciones y métodos para aumentar los niveles de plaquetas de la sangre en humanos |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07811274.5T Active ES2452032T3 (es) | 2006-08-08 | 2007-08-08 | Composiciones y métodos para aumentar los niveles de plaquetas de la sangre en humanos |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20080039475A1 (https=) |
| EP (2) | EP2452674B1 (https=) |
| JP (3) | JP2010500361A (https=) |
| AU (2) | AU2007284644B2 (https=) |
| CA (1) | CA2660283C (https=) |
| ES (2) | ES2470333T3 (https=) |
| IL (4) | IL196897A (https=) |
| WO (1) | WO2008021283A2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1466912T3 (da) | 2002-01-18 | 2013-07-01 | Astellas Pharma Inc | 2-acylaminothiazolderivat eller salt deraf |
| EP2464352A1 (en) * | 2009-08-14 | 2012-06-20 | Eisai Inc. | Use of e5501 for stimulating platelet production |
| CN112022825B (zh) * | 2020-08-24 | 2024-03-22 | 瑞阳制药股份有限公司 | 马来酸阿伐曲泊帕片剂及其制备方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5330998A (en) * | 1988-03-08 | 1994-07-19 | Pfizer Inc. | Thiazolidinedione derivatives as hypoglycemic agents |
| US5256675A (en) * | 1989-08-07 | 1993-10-26 | Fujisawa Pharmaceutical Co., Ltd. | Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same |
| IE68593B1 (en) * | 1989-12-06 | 1996-06-26 | Sanofi Sa | Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them |
| FR2677356B1 (fr) * | 1991-06-05 | 1995-03-17 | Sanofi Sa | Derives heterocycliques d'acylamino-2 thiazoles-5 substitues, leur preparation et compositions pharmaceutiques en contenant. |
| US5250732A (en) * | 1991-07-18 | 1993-10-05 | Genentech, Inc. | Ketamine analogues for treatment of thrombocytopenia |
| GB9126677D0 (en) * | 1991-12-16 | 1992-02-12 | Johnson Matthey Plc | Improvements in chemical compounds |
| EP0620403B1 (de) * | 1993-04-08 | 1996-12-04 | ABB Management AG | Misch- und Flammenstabilisierungseinrichtung in einer Brennkammer mit Vormischverbrennung |
| EP0768311B1 (en) * | 1995-03-09 | 2003-08-06 | Kyowa Hakko Kogyo Co., Ltd. | Pyrrolocarbazole derivatives |
| EP0823423B1 (en) * | 1995-04-28 | 2004-06-16 | Banyu Pharmaceutical Co., Ltd. | 1,4-disubstituted piperidine derivatives |
| TR199701526T1 (xx) * | 1995-06-07 | 1998-03-21 | Glaxo Group Limited | Bir trombopoietin resept�r�ne ba�lanan peptitler ve bile�ikler. |
| US5963666A (en) * | 1995-08-18 | 1999-10-05 | International Business Machines Corporation | Confusion matrix mediated word prediction |
| AU702751B2 (en) * | 1995-10-17 | 1999-03-04 | Daiichi Suntory Pharma Co., Ltd | Therapeutics for thrombocytopenia |
| US5932546A (en) * | 1996-10-04 | 1999-08-03 | Glaxo Wellcome Inc. | Peptides and compounds that bind to the thrombopoietin receptor |
| US6187797B1 (en) * | 1996-12-23 | 2001-02-13 | Dupont Pharmaceuticals Company | Phenyl-isoxazoles as factor XA Inhibitors |
| WO2000017175A1 (en) * | 1998-09-18 | 2000-03-30 | Vertex Pharmaceuticals Incorporated | INHIBITORS OF p38 |
| JP2002529502A (ja) * | 1998-11-17 | 2002-09-10 | スミスクライン・ビーチャム・コーポレイション | 血小板減少症の治療法 |
| TWI284639B (en) * | 2000-01-24 | 2007-08-01 | Shionogi & Co | A compound having thrombopoietin receptor agonistic effect |
| GB0028383D0 (en) * | 2000-11-21 | 2001-01-03 | Novartis Ag | Organic compounds |
| CA2437248A1 (en) * | 2001-02-02 | 2002-08-15 | Takeda Chemical Industries, Ltd. | Jnk inhibitor |
| JPWO2002062775A1 (ja) * | 2001-02-02 | 2004-06-10 | 山之内製薬株式会社 | ２−アシルアミノチアゾール誘導体又はその塩 |
| DK1466912T3 (da) * | 2002-01-18 | 2013-07-01 | Astellas Pharma Inc | 2-acylaminothiazolderivat eller salt deraf |
| BR0312023A (pt) * | 2002-06-27 | 2005-03-22 | Novo Nordisk As | Composto, composto ativador da glicose cinase, método para evitar a hipoglicemia, uso de um composto, e, composição farmacêutica |
| WO2004029049A1 (ja) * | 2002-09-30 | 2004-04-08 | Yamanouchi Pharmaceutical Co., Ltd. | 2-アシルアミノチアゾール誘導体の新規な塩 |
| US20040235834A1 (en) * | 2003-03-25 | 2004-11-25 | Farmer Luc J. | Thiazoles useful as inhibitors of protein kinases |
| CA2529686C (en) * | 2003-07-17 | 2010-06-15 | Astellas Pharma Inc. | 2-acylaminothiazole derivative or salt thereof |
| WO2005014561A1 (ja) * | 2003-08-12 | 2005-02-17 | Shionogi & Co., Ltd. | トロンボポエチン受容体アゴニスト作用を有する化合物 |
| CA2628848A1 (en) * | 2005-11-08 | 2007-05-18 | Astellas Pharma Inc. | Compositions and methods for treating thrombocytopenia |
-
2007
- 2007-08-08 EP EP11190964.4A patent/EP2452674B1/en active Active
- 2007-08-08 ES ES11190964.4T patent/ES2470333T3/es active Active
- 2007-08-08 US US11/891,133 patent/US20080039475A1/en not_active Abandoned
- 2007-08-08 EP EP07811274.5A patent/EP2056826B1/en active Active
- 2007-08-08 AU AU2007284644A patent/AU2007284644B2/en active Active
- 2007-08-08 JP JP2009523867A patent/JP2010500361A/ja active Pending
- 2007-08-08 ES ES07811274.5T patent/ES2452032T3/es active Active
- 2007-08-08 WO PCT/US2007/017860 patent/WO2008021283A2/en not_active Ceased
- 2007-08-08 CA CA2660283A patent/CA2660283C/en active Active
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2009
- 2009-02-04 IL IL196897A patent/IL196897A/en active IP Right Grant
-
2011
- 2011-03-31 US US13/077,736 patent/US20110224226A1/en not_active Abandoned
- 2011-12-01 AU AU2011253775A patent/AU2011253775B2/en active Active
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2012
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2015
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- 2015-08-03 IL IL240323A patent/IL240323A/en active IP Right Grant
- 2015-08-03 IL IL240322A patent/IL240322A0/en unknown
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2016
- 2016-05-29 IL IL245911A patent/IL245911A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007284644B2 (en) | 2011-09-01 |
| EP2452674B1 (en) | 2014-03-26 |
| AU2007284644A1 (en) | 2008-02-21 |
| EP2056826A2 (en) | 2009-05-13 |
| IL240323A (en) | 2016-05-31 |
| JP2013047257A (ja) | 2013-03-07 |
| WO2008021283A3 (en) | 2008-12-11 |
| JP2010500361A (ja) | 2010-01-07 |
| EP2056826B1 (en) | 2014-01-08 |
| AU2011253775B2 (en) | 2014-02-13 |
| IL196897A (en) | 2015-08-31 |
| AU2011253775A1 (en) | 2011-12-22 |
| HK1170673A1 (en) | 2013-03-08 |
| JP2015221806A (ja) | 2015-12-10 |
| IL240323A0 (en) | 2015-09-24 |
| EP2452674A2 (en) | 2012-05-16 |
| IL245911A0 (en) | 2016-07-31 |
| IL196897A0 (en) | 2011-08-01 |
| IL240322A0 (en) | 2015-09-24 |
| JP6258264B2 (ja) | 2018-01-10 |
| US20080039475A1 (en) | 2008-02-14 |
| CA2660283A1 (en) | 2008-02-21 |
| US20110224226A1 (en) | 2011-09-15 |
| EP2452674A3 (en) | 2012-05-30 |
| EP2056826A4 (en) | 2009-09-09 |
| CA2660283C (en) | 2014-11-18 |
| WO2008021283A2 (en) | 2008-02-21 |
| ES2452032T3 (es) | 2014-03-31 |
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