ES2389751T3 - Un nuevo biomarcador para monitorizar el desarrollo de enfermedades y evaluar la eficacia de terapias - Google Patents

Un nuevo biomarcador para monitorizar el desarrollo de enfermedades y evaluar la eficacia de terapias Download PDF

Info

Publication number
ES2389751T3
ES2389751T3 ES08842581T ES08842581T ES2389751T3 ES 2389751 T3 ES2389751 T3 ES 2389751T3 ES 08842581 T ES08842581 T ES 08842581T ES 08842581 T ES08842581 T ES 08842581T ES 2389751 T3 ES2389751 T3 ES 2389751T3
Authority
ES
Spain
Prior art keywords
disease
level
activity
mice
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08842581T
Other languages
English (en)
Spanish (es)
Inventor
Sirpa Jalkanen
Marko Salmi
Markku Jalkanen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Faron Pharmaceuticals Oy
Original Assignee
Faron Pharmaceuticals Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Faron Pharmaceuticals Oy filed Critical Faron Pharmaceuticals Oy
Application granted granted Critical
Publication of ES2389751T3 publication Critical patent/ES2389751T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/24Immunology or allergic disorders
    • G01N2800/245Transplantation related diseases, e.g. graft versus host disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • G01N2800/324Coronary artery diseases, e.g. angina pectoris, myocardial infarction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
ES08842581T 2007-10-24 2008-10-15 Un nuevo biomarcador para monitorizar el desarrollo de enfermedades y evaluar la eficacia de terapias Active ES2389751T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI20070795 2007-10-24
FI20070795A FI20070795A0 (fi) 2007-10-24 2007-10-24 Uusi biomarkkeri sairauksien kehittämisen tarkkailuun ja terapioiden tehon arviointiin
PCT/FI2008/050576 WO2009053523A1 (en) 2007-10-24 2008-10-15 A new biomarker for monitoring development of diseases and assessing the efficacy of therapies

Publications (1)

Publication Number Publication Date
ES2389751T3 true ES2389751T3 (es) 2012-10-31

Family

ID=38656804

Family Applications (2)

Application Number Title Priority Date Filing Date
ES08842581T Active ES2389751T3 (es) 2007-10-24 2008-10-15 Un nuevo biomarcador para monitorizar el desarrollo de enfermedades y evaluar la eficacia de terapias
ES12002502.8T Active ES2532361T3 (es) 2007-10-24 2008-10-15 CD73 como biomarcador para monitorizar el desarrollo de enfermedades y evaluar la eficacia de terapias

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES12002502.8T Active ES2532361T3 (es) 2007-10-24 2008-10-15 CD73 como biomarcador para monitorizar el desarrollo de enfermedades y evaluar la eficacia de terapias

Country Status (14)

Country Link
US (1) US20100209942A1 (cg-RX-API-DMAC7.html)
EP (2) EP2201376B1 (cg-RX-API-DMAC7.html)
JP (2) JP4982610B2 (cg-RX-API-DMAC7.html)
KR (2) KR20100059902A (cg-RX-API-DMAC7.html)
CA (1) CA2702635A1 (cg-RX-API-DMAC7.html)
CY (2) CY1113403T1 (cg-RX-API-DMAC7.html)
DK (2) DK2201376T3 (cg-RX-API-DMAC7.html)
ES (2) ES2389751T3 (cg-RX-API-DMAC7.html)
FI (1) FI20070795A0 (cg-RX-API-DMAC7.html)
HR (2) HRP20120743T1 (cg-RX-API-DMAC7.html)
PL (2) PL2201376T3 (cg-RX-API-DMAC7.html)
PT (2) PT2503338E (cg-RX-API-DMAC7.html)
SI (2) SI2503338T1 (cg-RX-API-DMAC7.html)
WO (1) WO2009053523A1 (cg-RX-API-DMAC7.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX340916B (es) 2008-01-18 2016-07-29 President And Fellows Of Harvard College * Metodos para detectar señales de identificacion de enfermedad o condiciones en fluidos corporales.
AU2011281012A1 (en) 2010-07-23 2013-02-28 President And Fellows Of Harvard College Methods of detecting cardiovascular diseases or conditions
TW201209171A (en) 2010-07-23 2012-03-01 Harvard College Methods of detecting diseases or conditions using phagocytic cells
US20130203624A1 (en) 2010-07-23 2013-08-08 President And Fellows Of Harvard College Methods of Detecting Prenatal or Pregnancy-Related Diseases or Conditions
AU2011280997A1 (en) 2010-07-23 2013-02-28 President And Fellows Of Harvard College Methods of detecting autoimmune or immune-related diseases or conditions
EP2596132A4 (en) 2010-07-23 2013-12-18 Harvard College METHOD FOR DETECTING SIGNS FOR ILLNESS OR SUFFERING IN BODY FLUIDS
JP2015522260A (ja) 2012-06-15 2015-08-06 ハリー スティリ, 疾患または状態を検出する方法
MX2014015434A (es) 2012-06-15 2015-07-14 Harry Stylli Metodos para detectar enfermedades o condiciones utilizando celulas enfermas en circulacion.
PL2956772T3 (pl) * 2013-02-14 2018-12-31 Faron Pharmaceuticals Oy Sposób określenia biomarkerów związanych z zespołem ostrej niewydolności oddechowej (ARDS), sposób monitorowania rozwoju i leczenia ARDS u pacjenta
NZ771629A (en) 2013-03-09 2022-12-23 Harry Stylli Methods of detecting cancer
WO2014164362A1 (en) 2013-03-09 2014-10-09 Harry Stylli Methods of detecting prostate cancer
US10626464B2 (en) 2014-09-11 2020-04-21 Cell Mdx, Llc Methods of detecting prostate cancer
AU2015349878A1 (en) 2014-11-21 2017-05-25 Bristol-Myers Squibb Company Antibodies against CD73 and uses thereof
JP6668345B2 (ja) 2014-11-21 2020-03-18 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company 修飾された重鎖定常領域を含む抗体
GB201706747D0 (en) * 2017-04-27 2017-06-14 Queen Mary Method and apparatus for determining the efficacy of statins for treating inflammatory diseases in idividual patients

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002515965A (ja) * 1995-08-18 2002-05-28 ダブリュー. ランドリ,ドナルド 抗体触媒反応の調節による有機化合物の検出
EP0862652A1 (en) 1995-10-13 1998-09-09 IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY & MEDICINE Methods for predicting the outcome of persistent hbv infection and the outcome of cytokine therapy
HUP0002003A3 (en) 2000-05-24 2003-01-28 Pronuk Biotechnologia Kft Process and reagent-kit for determining of 5'-nucleotidase activity
CA2439961A1 (en) * 2001-03-27 2002-10-03 Zymogenetics, Inc. Human cytokine receptor
WO2004079013A1 (en) * 2003-03-03 2004-09-16 Arizona Board Of Regents On Behalf Of The University Of Arizona Ecto-5’-nucleotidase (cd73) used in the diagnosis and the treatment of pancreatic cancer
FI20030467A0 (fi) * 2003-03-28 2003-03-28 Sirpa Jalkanen Menetelmä tulehdustilojen hoitamiseen
US7534423B2 (en) 2003-03-28 2009-05-19 Faron Pharmaceuticals Oy Method for inducing an elevated level of adenosine in an individual
CA2528152A1 (en) * 2003-06-03 2005-01-06 The Regents Of The University Of California Compositions and methods for treatment of disease with acetylated disaccharides
JP2009505658A (ja) * 2005-08-24 2009-02-12 ブリストル−マイヤーズ スクイブ カンパニー 上皮増殖因子受容体モデュレーターに対する感受性を決定するためのバイオマーカーおよび方法
FI20051003A0 (fi) 2005-10-07 2005-10-07 Faron Pharmaceuticals Oy Menetelmä iskemiareperfuusiovaurion tai monielinhäiriön hoitamiseksi tai estämiseksi
EP2021350B1 (en) * 2006-03-21 2016-12-21 Rheinische Friedrich-Wilhelms-Universität Bonn Phosphorylated a2a receptor agonists
EP2041574B1 (en) * 2006-07-14 2016-11-16 The Regents of The University of California Cancer biomarkers and methods of use threof

Also Published As

Publication number Publication date
PT2503338E (pt) 2015-03-05
WO2009053523A1 (en) 2009-04-30
CA2702635A1 (en) 2009-04-30
ES2532361T3 (es) 2015-03-26
EP2201376B1 (en) 2012-08-08
EP2503338B1 (en) 2014-12-24
JP5619810B2 (ja) 2014-11-05
PL2201376T3 (pl) 2013-01-31
SI2503338T1 (sl) 2015-06-30
US20100209942A1 (en) 2010-08-19
HRP20120743T1 (hr) 2012-10-31
EP2201376A1 (en) 2010-06-30
JP2012159514A (ja) 2012-08-23
EP2201376A4 (en) 2011-03-23
FI20070795A0 (fi) 2007-10-24
DK2201376T3 (da) 2012-10-15
JP4982610B2 (ja) 2012-07-25
CY1116089T1 (el) 2017-02-08
PL2503338T3 (pl) 2015-06-30
EP2503338A2 (en) 2012-09-26
JP2011501176A (ja) 2011-01-06
CY1113403T1 (el) 2016-06-22
KR20160029869A (ko) 2016-03-15
SI2201376T1 (sl) 2012-09-28
KR20100059902A (ko) 2010-06-04
DK2503338T3 (en) 2015-03-09
HRP20150181T1 (hr) 2015-06-19
EP2503338A3 (en) 2013-03-13
PT2201376E (pt) 2012-08-20

Similar Documents

Publication Publication Date Title
ES2389751T3 (es) Un nuevo biomarcador para monitorizar el desarrollo de enfermedades y evaluar la eficacia de terapias
Heper et al. Evaluation of serum C-reactive protein, procalcitonin, tumor necrosis factor alpha, and interleukin-10 levels as diagnostic and prognostic parameters in patients with community-acquired sepsis, severe sepsis, and septic shock
ES2718731T3 (es) Métodos, dispositivos y kits para detectar o monitorizar la lesión renal aguda
Hartmann et al. High altitude increases circulating interleukin-6, interleukin-1 receptor antagonist and C-reactive protein
US20150355180A1 (en) Differential Expression of Novel Protein Markers for the Diagnosis and Treatment of Eosinophilic Esophagitis
Gedik et al. Potential humoral mediators of remote ischemic preconditioning in patients undergoing surgical coronary revascularization
Mukama et al. A highly sensitive and specific lateral flow aptasensor for the detection of human osteopontin
ES2772701T3 (es) Uso de nucleosomas libres de células como biomarcadores en muestras de esputo
Cibor et al. Serum galectin 3, galectin 9 and galectin 3-binding proteins in patients with active and inactive inflammatory bowel disease.
Knabe et al. CCSP counterbalances airway epithelial-driven neutrophilic chemotaxis
Makieieva et al. Are level of IL-13 and IL-4 predictive for formation of chronic inflammation in children with asthma?
Covarrubias-Zambrano et al. Optical biosensing of markers of mucosal inflammation
Engebretsen et al. Acute hypobaric hypoxia (5486 m) induces greater pulmonary HIF-1 activation in hilltop compared to madison rats
ES2376459T3 (es) Procedimiento de diagnóstico de la hipertensión arterial pulmonar.
Jung et al. Correlation between soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) expression and endoscopic activity in inflammatory bowel diseases
ES2851798T3 (es) Método y dispositivo para discriminar entre infecciones virales y bacterianas
Takahata et al. Postoperative serum concentrations of high mobility group box chromosomal protein-1 correlates to the duration of SIRS and pulmonary dysfunction following gastrointestinal surgery
BR112019024966A2 (pt) Método para diagnosticar ou monitorar a função renal ou diagnosticar a disfunção renal
Veldeman et al. Levels of bioactive adrenomedullin in plasma and cerebrospinal fluid in relation to delayed cerebral ischemia in patients after aneurysmal subarachnoid hemorrhage: A prospective observational study
ES2697299B2 (es) Biomarcadores diferenciales de asma
Çelik et al. Cytokine release syndrome in Crimean-Congo hemorrhagic fever: can IL-1 receptor antagonist levels be a guide in its treatment?
Yang et al. Total and double-stranded DNA-specific immunoglobulin E in bronchoalveolar lavage fluid of children with human adenovirus pneumonia
Kurt et al. Evaluation of fetuin-A, CRP, and CRP/fetuin-A values in COVID-19 patients
Lewandowska-Polak et al. 2 Lack of Association Between Aspirin-Triggered 15-Hydroxyeicosatetraenoic Acid Release and Mast Cell/Eosinophil Activation in Nasal Polyps From Aspirin-Sensitive Patients
Hafez et al. Serum soluble CD93 as a biomarker of asthma exacerbation in children