ES2374458T3 - Vacunas y agentes inmunoterapéuticos que utilizan il-15 optimizada en codones, y métodos para utilización de los mismos. - Google Patents
Vacunas y agentes inmunoterapéuticos que utilizan il-15 optimizada en codones, y métodos para utilización de los mismos. Download PDFInfo
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Applications Claiming Priority (3)
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| US75885606P | 2006-01-13 | 2006-01-13 | |
| US758856P | 2006-01-13 | ||
| PCT/US2007/000886 WO2007087178A2 (en) | 2006-01-13 | 2007-01-12 | Vaccines and immunotherapeutics using codon optimized il-15 and methods for using the same |
Publications (1)
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| ES2374458T3 true ES2374458T3 (es) | 2012-02-16 |
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| EP (1) | EP1976871B1 (enExample) |
| JP (2) | JP5346588B2 (enExample) |
| KR (1) | KR101421745B1 (enExample) |
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| AT (1) | ATE533782T1 (enExample) |
| AU (1) | AU2007208452B2 (enExample) |
| CA (1) | CA2636867C (enExample) |
| DK (1) | DK1976871T3 (enExample) |
| ES (1) | ES2374458T3 (enExample) |
| MX (1) | MX336112B (enExample) |
| WO (1) | WO2007087178A2 (enExample) |
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| DK1976871T3 (da) * | 2006-01-13 | 2011-12-12 | Univ Pennsylvania | Vacciner og immunterapeutika under anvendelse af codonoptimerede IL-15 og fremgangsmåder til anvendelse deraf |
| US8822663B2 (en) | 2010-08-06 | 2014-09-02 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| CA2821992A1 (en) | 2010-10-01 | 2012-04-05 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| WO2012109788A1 (zh) * | 2011-02-16 | 2012-08-23 | 中国水产科学研究院黄海水产研究所 | 一种提高蛋白表达效率的方法及表达载体 |
| DE12722942T1 (de) | 2011-03-31 | 2021-09-30 | Modernatx, Inc. | Freisetzung und formulierung von manipulierten nukleinsäuren |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| HRP20220250T1 (hr) | 2011-10-03 | 2022-04-29 | Modernatx, Inc. | Modificirani nukleozidi, nukleotidi i nukleinske kiseline, te njihove uporabe |
| SI2791160T1 (sl) | 2011-12-16 | 2022-07-29 | Modernatx, Inc. | Sestave modificirane MRNA |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| US10501512B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides |
| AU2013243952A1 (en) | 2012-04-02 | 2014-10-30 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| SMT202200337T1 (it) | 2012-11-26 | 2022-09-14 | Modernatx Inc | Rna modificato al livello del terminale |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| US10023626B2 (en) | 2013-09-30 | 2018-07-17 | Modernatx, Inc. | Polynucleotides encoding immune modulating polypeptides |
| US10323076B2 (en) | 2013-10-03 | 2019-06-18 | Modernatx, Inc. | Polynucleotides encoding low density lipoprotein receptor |
| SG10201912038TA (en) | 2014-04-23 | 2020-02-27 | Modernatx Inc | Nucleic acid vaccines |
| AU2015323944B2 (en) * | 2014-10-01 | 2018-11-29 | Inovio Pharmaceuticals, Inc. | Vaccines having an antigen and interleukin-21 as an adjuvant |
| AU2017268394A1 (en) | 2016-05-18 | 2019-01-03 | Modernatx, Inc. | Polynucleotides encoding relaxin |
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| CN107868131A (zh) * | 2017-10-13 | 2018-04-03 | 长春西诺生物科技有限公司 | 一种猪细小病毒病亚单位疫苗及其制备方法 |
| WO2019118760A1 (en) | 2017-12-13 | 2019-06-20 | Inovio Pharmaceuticals, Inc. | Cancer vaccines targeting mesothelin and uses thereof |
| RU2750689C1 (ru) | 2017-12-13 | 2021-07-01 | Иновио Фармасьютикалз, Инк. | Противораковые вакцины, направленные на muc16, и их применение |
| JP7485600B2 (ja) | 2017-12-13 | 2024-05-16 | イノビオ ファーマシューティカルズ，インコーポレイティド | Ｂｏｒｉｓを標的とするがんワクチンおよびその使用 |
| JP7273421B2 (ja) | 2018-02-21 | 2023-05-15 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用 |
| US11419898B2 (en) | 2018-10-17 | 2022-08-23 | Senti Biosciences, Inc. | Combinatorial cancer immunotherapy |
| AU2019359890B2 (en) | 2018-10-17 | 2024-10-24 | Senti Biosciences, Inc. | Combinatorial cancer immunotherapy |
| EP4306641A4 (en) * | 2021-02-05 | 2025-06-04 | ST Pharm Co., Ltd. | NEW NUCLEIC ACID MOLECULE |
| US20230151095A1 (en) | 2021-11-12 | 2023-05-18 | Xencor, Inc. | Bispecific antibodies that bind to b7h3 and nkg2d |
| WO2024102636A1 (en) | 2022-11-07 | 2024-05-16 | Xencor, Inc. | Bispecific antibodies that bind to b7h3 and mica/b |
| WO2025085672A1 (en) | 2023-10-17 | 2025-04-24 | Xencor, Inc. | Bispecific antibodies that bind to nkp46 and mica/b |
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Also Published As
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| ATE533782T1 (de) | 2011-12-15 |
| US20100003277A1 (en) | 2010-01-07 |
| JP2013051972A (ja) | 2013-03-21 |
| AU2007208452B2 (en) | 2012-07-05 |
| US8592567B2 (en) | 2013-11-26 |
| JP2009523422A (ja) | 2009-06-25 |
| CN101432300A (zh) | 2009-05-13 |
| JP5801279B2 (ja) | 2015-10-28 |
| US20120213815A1 (en) | 2012-08-23 |
| KR20080094044A (ko) | 2008-10-22 |
| US8178660B2 (en) | 2012-05-15 |
| EP1976871A4 (en) | 2009-05-13 |
| JP5346588B2 (ja) | 2013-11-20 |
| MX336112B (es) | 2016-01-08 |
| EP1976871A2 (en) | 2008-10-08 |
| KR101421745B1 (ko) | 2014-07-22 |
| DK1976871T3 (da) | 2011-12-12 |
| EP1976871B1 (en) | 2011-11-16 |
| WO2007087178A2 (en) | 2007-08-02 |
| AU2007208452A1 (en) | 2007-08-02 |
| CA2636867C (en) | 2015-12-01 |
| CA2636867A1 (en) | 2007-08-02 |
| WO2007087178A3 (en) | 2008-01-03 |
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