ES2374403T3 - Cuantificación de anticuerpos. - Google Patents
Cuantificación de anticuerpos. Download PDFInfo
- Publication number
- ES2374403T3 ES2374403T3 ES07865898T ES07865898T ES2374403T3 ES 2374403 T3 ES2374403 T3 ES 2374403T3 ES 07865898 T ES07865898 T ES 07865898T ES 07865898 T ES07865898 T ES 07865898T ES 2374403 T3 ES2374403 T3 ES 2374403T3
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/6857—Antibody fragments
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biophysics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87137806P | 2006-12-21 | 2006-12-21 | |
| US871378P | 2006-12-21 | ||
| PCT/US2007/088258 WO2008079914A1 (en) | 2006-12-21 | 2007-12-20 | Antibody quantitation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2374403T3 true ES2374403T3 (es) | 2012-02-16 |
Family
ID=39247371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07865898T Active ES2374403T3 (es) | 2006-12-21 | 2007-12-20 | Cuantificación de anticuerpos. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20100015652A1 (de) |
| EP (1) | EP2097756B1 (de) |
| JP (1) | JP2010515020A (de) |
| AT (1) | ATE529752T1 (de) |
| ES (1) | ES2374403T3 (de) |
| WO (1) | WO2008079914A1 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2508880B1 (de) * | 2007-08-24 | 2013-11-13 | EMD Millipore Corporation | System zur Umleitung eines Flüssigchromatographie-Elutionsmittels |
| JP2010537196A (ja) | 2007-08-24 | 2010-12-02 | ミリポア・コーポレーション | バイオ医薬生成物中の抽出性物質を検出する方法 |
| WO2010086386A1 (en) * | 2009-01-30 | 2010-08-05 | Pronota N.V. | Protein quantification methods and use thereof for candidate biomarker validation |
| WO2010096154A2 (en) * | 2009-02-20 | 2010-08-26 | Onconome, Inc. | Compositions and methods for diagnosis and prognosis of colorectal cancer |
| EP2572203B1 (de) | 2010-05-17 | 2017-10-25 | The Board of Regents of The University of Texas System | Bestimmung von Antigen-spezifischen Antikörpersequenzen im Blutkreislauf |
| CN108220297A (zh) | 2011-03-09 | 2018-06-29 | 细胞信号科技公司 | 用于生成单克隆抗体的方法和试剂 |
| US8679767B2 (en) | 2011-05-12 | 2014-03-25 | Genentech, Inc. | Multiple reaction monitoring LC-MS/MS method to detect therapeutic antibodies in animal samples using framework signature peptides |
| GB201110371D0 (en) * | 2011-06-17 | 2011-08-03 | Proteome Sciences R & D Gmbh & Co Kg | Materials and methods for determining sensitivity potential of compounds |
| EP2783214A2 (de) | 2011-11-23 | 2014-10-01 | The Board of Regents of The University of Texas System | Proteomischer nachweis von antikörpern |
| EP2861760B1 (de) | 2012-06-15 | 2020-01-01 | The Board of Regents of The University of Texas System | Sequenzierung von mehreren transkripten aus einer einzelnen zelle mit hohem durchsatz |
| DK3387898T3 (da) | 2013-03-15 | 2020-08-03 | Mayo Found Medical Education & Res | Identificering og monitorering af monoklonale immunglobuliner ved hjælp af molekylvægt |
| EP3023777B1 (de) | 2013-09-09 | 2017-11-15 | Shimadzu Corporation | Verfahren zur herstellung von peptidfragmenten, darin verwendetes kit zur herstellung von peptidfragmenten und analyseverfahren |
| JP6742235B2 (ja) * | 2014-02-18 | 2020-08-19 | 株式会社島津製作所 | 質量分析を用いたタンパク質の検出方法 |
| CA2944767C (en) | 2014-04-04 | 2022-07-12 | Mayo Foundation For Medical Education And Research | Isotyping immunoglobulins using accurate molecular mass |
| BR112017017854A2 (pt) | 2015-03-09 | 2018-04-10 | Shimadzu Corporation | método para detecção de anticorpo monoclonal utilizando espectrometria de massa |
| CN115932065A (zh) | 2015-03-10 | 2023-04-07 | 株式会社岛津制作所 | 用于检测单克隆抗体的样品调制用试剂盒 |
| US10513733B2 (en) | 2015-03-23 | 2019-12-24 | Board Of Regents, The University Of Texas System | High throughout sequencing of paired VH and VL transcripts from B cells secreting antigen-specific antibodies |
| EP3353200A4 (de) | 2015-09-24 | 2019-06-26 | Mayo Foundation for Medical Education and Research | Identifizierung von freien leichten ketten aus immunglobulin durch massenspektrometrie |
| GB201603291D0 (en) | 2016-02-25 | 2016-04-13 | Binding Site Group The Ltd | Antibodies |
| JP7022080B2 (ja) | 2016-05-27 | 2022-02-17 | ジェネンテック， インコーポレイテッド | 部位特異的抗体－薬物複合体の特徴付けのための生化学分析的方法 |
| KR20230041834A (ko) * | 2016-08-16 | 2023-03-24 | 리제너론 파아마슈티컬스, 인크. | 혼합물로부터 개별 항체들을 정량하는 방법 |
| EP3523647B1 (de) | 2016-09-07 | 2024-06-26 | Mayo Foundation for Medical Education and Research | Identifizierung und überwachung von gespaltenen immunglobulinen nach molekülmasse |
| EP3681528B1 (de) | 2017-09-13 | 2025-07-23 | Mayo Foundation for Medical Education and Research | Identifizierung und überwachung des apoptosehemmers von makrophagen |
| EP3681907A4 (de) | 2017-09-13 | 2021-07-07 | Mayo Foundation for Medical Education and Research | Identifizierung und überwachung von immunglobulin-j-ketten |
| WO2019084538A1 (en) | 2017-10-27 | 2019-05-02 | Board Of Regents, The University Of Texas System | TUMOR SPECIFIC ANTIBODIES, T CELL RECEPTORS AND METHODS OF IDENTIFICATION THEREOF |
| GB2607197B (en) * | 2018-06-06 | 2023-04-26 | Bruker Daltonics Gmbh & Co Kg | Targeted protein characterization by mass spectrometry |
| MX2022015461A (es) * | 2020-06-09 | 2023-01-16 | Regeneron Pharma | Metodo basado en espectrometria de masas y de alto rendimiento para cuantificar anticuerpos. |
| JP7786458B2 (ja) * | 2021-06-23 | 2025-12-16 | 株式会社島津製作所 | 抗体を分析する方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3491748B2 (ja) * | 1999-07-22 | 2004-01-26 | 株式会社いかがく | 血液中の低比重リポ蛋白（ｌｄｌ）もしくは変性低比重リポ蛋白の検出方法 |
| JP4604345B2 (ja) * | 2000-12-21 | 2011-01-05 | 住友化学株式会社 | タンパク質のｎ末端のアミノ酸配列決定方法 |
| EP1457499A1 (de) * | 2003-03-12 | 2004-09-15 | Tufts University School Of Medicine | Inhibitoren des extrazellulären Hitzeschockproteins Hsp90 |
| WO2005101017A1 (en) * | 2004-04-07 | 2005-10-27 | Genentech, Inc. | Mass spectrometry of antibody conjugates |
-
2007
- 2007-12-20 WO PCT/US2007/088258 patent/WO2008079914A1/en not_active Ceased
- 2007-12-20 AT AT07865898T patent/ATE529752T1/de not_active IP Right Cessation
- 2007-12-20 EP EP07865898A patent/EP2097756B1/de not_active Not-in-force
- 2007-12-20 ES ES07865898T patent/ES2374403T3/es active Active
- 2007-12-20 JP JP2009543205A patent/JP2010515020A/ja active Pending
- 2007-12-20 US US12/520,031 patent/US20100015652A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008079914A1 (en) | 2008-07-03 |
| US20100015652A1 (en) | 2010-01-21 |
| EP2097756B1 (de) | 2011-10-19 |
| ATE529752T1 (de) | 2011-11-15 |
| EP2097756A1 (de) | 2009-09-09 |
| JP2010515020A (ja) | 2010-05-06 |
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