ES2363689T3 - Anticuerpos monoclonales y quiméricos, opsónicos y protectores, específicos para el ácido lipoteicoico de bacterías gram positivas. - Google Patents

Anticuerpos monoclonales y quiméricos, opsónicos y protectores, específicos para el ácido lipoteicoico de bacterías gram positivas. Download PDF

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Publication number
ES2363689T3
ES2363689T3 ES98931278T ES98931278T ES2363689T3 ES 2363689 T3 ES2363689 T3 ES 2363689T3 ES 98931278 T ES98931278 T ES 98931278T ES 98931278 T ES98931278 T ES 98931278T ES 2363689 T3 ES2363689 T3 ES 2363689T3
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antibody
seq
type
sequence
binding fragment
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Expired - Lifetime
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ES98931278T
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English (en)
Spanish (es)
Inventor
Gerald W. Fischer
Richard F. Schuman
Hing Wong
Jeffrey L. Stinson
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Henry M Jackson Foundation for Advancedment of Military Medicine Inc
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Henry M Jackson Foundation for Advancedment of Military Medicine Inc
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES98931278T 1997-06-16 1998-06-16 Anticuerpos monoclonales y quiméricos, opsónicos y protectores, específicos para el ácido lipoteicoico de bacterías gram positivas. Expired - Lifetime ES2363689T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4987197P 1997-06-16 1997-06-16
US49871P 1997-06-16

Publications (1)

Publication Number Publication Date
ES2363689T3 true ES2363689T3 (es) 2011-08-11

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Family Applications (1)

Application Number Title Priority Date Filing Date
ES98931278T Expired - Lifetime ES2363689T3 (es) 1997-06-16 1998-06-16 Anticuerpos monoclonales y quiméricos, opsónicos y protectores, específicos para el ácido lipoteicoico de bacterías gram positivas.

Country Status (10)

Country Link
US (5) US6610293B1 (enExample)
EP (2) EP2357198A1 (enExample)
JP (2) JP4691225B2 (enExample)
AT (1) ATE497977T1 (enExample)
AU (1) AU8144098A (enExample)
CA (1) CA2293732A1 (enExample)
DE (1) DE69842129D1 (enExample)
DK (1) DK0986577T3 (enExample)
ES (1) ES2363689T3 (enExample)
WO (1) WO1998057994A2 (enExample)

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JP2011026327A (ja) 2011-02-10
US20100221822A1 (en) 2010-09-02
WO1998057994A2 (en) 1998-12-23
AU8144098A (en) 1999-01-04
US7884198B2 (en) 2011-02-08
US8372958B2 (en) 2013-02-12
JP2002503966A (ja) 2002-02-05
JP4691225B2 (ja) 2011-06-01
WO1998057994A3 (en) 1999-03-25
DK0986577T3 (da) 2011-05-23
EP0986577B1 (en) 2011-02-09
EP2357198A1 (en) 2011-08-17
ATE497977T1 (de) 2011-02-15
US20040013673A1 (en) 2004-01-22
CA2293732A1 (en) 1998-12-23
US20020082395A1 (en) 2002-06-27
US7511122B2 (en) 2009-03-31
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US6610293B1 (en) 2003-08-26
US20060002939A1 (en) 2006-01-05

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