ES2351620T3 - Procedimiento de preparación de células aviarias diferenciadas y genes implicados en el mantenimiento de la pluripotencia. - Google Patents

Procedimiento de preparación de células aviarias diferenciadas y genes implicados en el mantenimiento de la pluripotencia. Download PDF

Info

Publication number
ES2351620T3
ES2351620T3 ES07727050T ES07727050T ES2351620T3 ES 2351620 T3 ES2351620 T3 ES 2351620T3 ES 07727050 T ES07727050 T ES 07727050T ES 07727050 T ES07727050 T ES 07727050T ES 2351620 T3 ES2351620 T3 ES 2351620T3
Authority
ES
Spain
Prior art keywords
cells
expression
rna
differentiation
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07727050T
Other languages
English (en)
Spanish (es)
Inventor
Bertrand Pain
Fabrice Lavial
Jacques Samarut
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Institut National de la Recherche Agronomique INRA
Ecole Normale Superieure de Lyon
Original Assignee
Centre National de la Recherche Scientifique CNRS
Institut National de la Recherche Agronomique INRA
Ecole Normale Superieure de Lyon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Institut National de la Recherche Agronomique INRA, Ecole Normale Superieure de Lyon filed Critical Centre National de la Recherche Scientifique CNRS
Application granted granted Critical
Publication of ES2351620T3 publication Critical patent/ES2351620T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/465—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from birds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/53—Physical structure partially self-complementary or closed
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
ES07727050T 2006-03-24 2007-03-19 Procedimiento de preparación de células aviarias diferenciadas y genes implicados en el mantenimiento de la pluripotencia. Active ES2351620T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0602597A FR2898908A1 (fr) 2006-03-24 2006-03-24 Procede de preparation de cellules aviaires differenciees et genes impliques dans le maintien de la pluripotence
FR0602597 2006-03-24

Publications (1)

Publication Number Publication Date
ES2351620T3 true ES2351620T3 (es) 2011-02-08

Family

ID=37055981

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07727050T Active ES2351620T3 (es) 2006-03-24 2007-03-19 Procedimiento de preparación de células aviarias diferenciadas y genes implicados en el mantenimiento de la pluripotencia.

Country Status (11)

Country Link
US (1) US20090311789A1 (da)
EP (2) EP2007882B1 (da)
JP (1) JP5124748B2 (da)
AT (1) ATE479744T1 (da)
AU (1) AU2007229556A1 (da)
CA (1) CA2647806A1 (da)
DE (1) DE602007008863D1 (da)
DK (1) DK2007882T3 (da)
ES (1) ES2351620T3 (da)
FR (1) FR2898908A1 (da)
WO (1) WO2007110341A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6071893B2 (ja) 2010-11-23 2017-02-01 カッパーアールエヌエー，インコーポレイテッド Ｎａｎｏｇへの天然アンチセンス転写物の阻害によるｎａｎｏｇ関連疾患の治療
FR3008992A1 (fr) * 2013-07-25 2015-01-30 Agronomique Inst Nat Rech Procede de selection d'une lignee cellulaire permissive pour la replication de virus aviaires
JP2016158577A (ja) * 2015-03-03 2016-09-05 富士フイルム株式会社 細胞コロニー検出装置および方法並びにプログラム
JP6925931B2 (ja) 2017-10-20 2021-08-25 日本スピンドル製造株式会社 バッチ式の混練機、及びバッチ式の混練機における羽根部の交換方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5456357A (en) 1994-07-07 1995-10-10 Wenner; John W. Nestable bucket and carrier
FR2726003B1 (fr) * 1994-10-21 2002-10-18 Agronomique Inst Nat Rech Milieu de culture de cellules embryonnaires totipotentes aviaires, procede de culture de ces cellules, et cellules embryonnaires totipotentes aviaires
US5914268A (en) 1994-11-21 1999-06-22 National Jewish Center For Immunology & Respiratory Medicine Embryonic cell populations and methods to isolate such populations
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
KR20010042069A (ko) 1998-03-20 2001-05-25 베니텍 오스트레일리아 리미티드 유전자 발현 조절방법
DE19956568A1 (de) 1999-01-30 2000-08-17 Roland Kreutzer Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
DE10160151A1 (de) 2001-01-09 2003-06-26 Ribopharma Ag Verfahren zur Hemmung der Expression eines vorgegebenen Zielgens
DE10100586C1 (de) 2001-01-09 2002-04-11 Ribopharma Ag Verfahren zur Hemmung der Expression eines Ziegens
AU2001245793A1 (en) 2000-03-16 2001-09-24 Cold Spring Harbor Laboratory Methods and compositions for rna interference
EP1272629A4 (en) 2000-03-17 2004-12-22 Benitec Australia Ltd gene silencing
KR101215789B1 (ko) 2000-03-30 2012-12-26 화이트헤드 인스티튜트 포 바이오메디칼 리서치 Ｒｎａ 간섭의 ｒｎａ 서열 특이적인 매개체
US6458589B1 (en) 2000-04-27 2002-10-01 Geron Corporation Hepatocyte lineage cells derived from pluripotent stem cells
CZ302719B6 (cs) 2000-12-01 2011-09-21 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Izolovaná molekula dvouretezcové RNA, zpusob její výroby a její použití
WO2003035869A1 (de) 2001-10-26 2003-05-01 Ribopharma Ag Verwendung einer doppelsträngigen ribonukleinsäure zur gezielten hemmung der expression eines vorgegebenen zielgens
WO2003008573A2 (en) 2001-07-17 2003-01-30 Anne Josephine Milner Silencing of gene expression by sirna
US20030198627A1 (en) 2001-09-01 2003-10-23 Gert-Jan Arts siRNA knockout assay method and constructs
DE10163098B4 (de) 2001-10-12 2005-06-02 Alnylam Europe Ag Verfahren zur Hemmung der Replikation von Viren
WO2003035870A1 (de) 2001-10-26 2003-05-01 Ribopharma Ag Medikament zur behandlung eines pankreaskarzinoms
WO2003035083A1 (de) 2001-10-26 2003-05-01 Ribopharma Ag Medikament zur behandlung einer fibrotischen erkrankung durch rna interferenz
DE10230996A1 (de) 2001-10-26 2003-07-17 Ribopharma Ag Medikament zur Behandlung eines Pankreaskarzinoms
CN1608133A (zh) 2001-10-26 2005-04-20 里伯药品公司 双链核糖核酸用于治疗正(+)链rna病毒感染的用途
EP1527176B2 (en) 2002-08-05 2017-03-22 Silence Therapeutics GmbH Further novel forms of interfering rna molecules
IL166718A0 (en) 2002-08-14 2006-01-15 Atugen Ag Further use of protein kinase n beta
PT1551868E (pt) 2002-10-18 2009-04-06 Silence Therapeutics Ag Factor envolvido nas metástases e as respectivas utilizações
EP1638580A2 (en) 2003-06-27 2006-03-29 atugen AG Use of double-stranded ribonucleic acid for inducing cell lysis

Also Published As

Publication number Publication date
DE602007008863D1 (de) 2010-10-14
US20090311789A1 (en) 2009-12-17
JP2009529899A (ja) 2009-08-27
ATE479744T1 (de) 2010-09-15
AU2007229556A1 (en) 2007-10-04
JP5124748B2 (ja) 2013-01-23
FR2898908A1 (fr) 2007-09-28
EP2007882B1 (fr) 2010-09-01
DK2007882T3 (da) 2010-12-20
EP2292739A1 (fr) 2011-03-09
EP2292739B1 (fr) 2012-09-12
CA2647806A1 (fr) 2007-10-04
WO2007110341A1 (fr) 2007-10-04
EP2007882A1 (fr) 2008-12-31

Similar Documents

Publication Publication Date Title
CN112424362A (zh) 使用来自青鳉属的转座酶将核酸构建体整合入真核细胞
Griffith et al. RNAi knockdown of the focal adhesion protein TES reveals its role in actin stress fibre organisation
CN111164209A (zh) 多能干细胞的分化能力的预测方法和用于该预测方法的试剂
ES2351620T3 (es) Procedimiento de preparación de células aviarias diferenciadas y genes implicados en el mantenimiento de la pluripotencia.
CN114645023B (zh) 将外周血单个核细胞重编程为诱导多能干细胞的系统和方法
US20210024915A1 (en) Method for activating p21 gene expression
CN110699487B (zh) 用于诊断禽白血病病毒肿瘤发生的反义rna及制备方法、应用和构建过表达载体的引物
CN114807136B (zh) 长链非编码RNA Gm10561在调控成肌细胞增殖分化中的应用
KR101133559B1 (ko) 인간 중배엽줄기세포 유래의 신규 ｍｉＲＮＡ
CN110066803B (zh) 一种调控神经干细胞中nestin基因表达的方法及靶向细胞的方法
CN108441496B (zh) 一种抑制鸡SOX5基因表达的shRNA序列及其应用
CA2752947A1 (en) Foxp1 splice variants and methods and uses thereof
JP4268169B2 (ja) 胚性幹細胞の自己複製決定因子
US9193952B2 (en) Methods for regulating neural differentiation
CN109762823B (zh) circ_1892及其在制备鼻咽癌治疗制剂中的应用和治疗制剂
WO2022272042A2 (en) Primordial germ cells
Kaira The role of Fragile-X mental retardation-related protein 1 in Human Adenovirus 5 infection
Becker Regulation of non-centrosomal microtubule organizing center formation in skeletal muscle cells
US8975068B2 (en) Isolated stem cell comprising a Xic flanking region transgene
Yun Biological roles for selective promotion of mature miRNA production by Argonautes
KR101304992B1 (ko) Ｊｍｊｄ３ 유전자의 발현을 억제시켜서 세포접착분자의 발현을 증가시키는 인공 마이크로 ｒｎａ
Al Fuhaid Expression of EZH1-Polycomb Repressive Complex 2 and MALAT1 lncRNA and their Combined Role in Epigenetic Adaptive Response
Ahiable Cloning candidate novel cell-fate genes (pre-implantation mouse development)
Fong The Role of SOX2 in Human Embryonic Stem Cells
Wilson MicroRNA-mediated silencing of bovine NANOG and MBD3