ES2347535T3 - Estabilizacion de composiciones acuosas de 2-fluoro-2-desoxi-d-glucosa marcada con el isotopo 18f con etanol. - Google Patents

Estabilizacion de composiciones acuosas de 2-fluoro-2-desoxi-d-glucosa marcada con el isotopo 18f con etanol. Download PDF

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Publication number
ES2347535T3
ES2347535T3 ES02773830T ES02773830T ES2347535T3 ES 2347535 T3 ES2347535 T3 ES 2347535T3 ES 02773830 T ES02773830 T ES 02773830T ES 02773830 T ES02773830 T ES 02773830T ES 2347535 T3 ES2347535 T3 ES 2347535T3
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ES
Spain
Prior art keywords
ethanol
fdg
concentration
fluoro
stabilization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES02773830T
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English (en)
Spanish (es)
Inventor
Maxim Y. Kiselev
Vincent Tadino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ion Beam Applications SA
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Ion Beam Applications SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32311616&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2347535(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ion Beam Applications SA filed Critical Ion Beam Applications SA
Application granted granted Critical
Publication of ES2347535T3 publication Critical patent/ES2347535T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
ES02773830T 2002-11-05 2002-11-05 Estabilizacion de composiciones acuosas de 2-fluoro-2-desoxi-d-glucosa marcada con el isotopo 18f con etanol. Expired - Lifetime ES2347535T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2002/033616 WO2004043497A1 (en) 2002-11-05 2002-11-05 Stabilzation of radiopharmceuticals labeled with 18-f

Publications (1)

Publication Number Publication Date
ES2347535T3 true ES2347535T3 (es) 2010-11-02

Family

ID=32311616

Family Applications (1)

Application Number Title Priority Date Filing Date
ES02773830T Expired - Lifetime ES2347535T3 (es) 2002-11-05 2002-11-05 Estabilizacion de composiciones acuosas de 2-fluoro-2-desoxi-d-glucosa marcada con el isotopo 18f con etanol.

Country Status (10)

Country Link
EP (2) EP2229957A3 (zh)
JP (1) JP2006505610A (zh)
KR (1) KR101001300B1 (zh)
CN (1) CN100478035C (zh)
AT (1) ATE473019T1 (zh)
AU (1) AU2002337926B8 (zh)
BR (1) BR0215913A (zh)
DE (1) DE60236971D1 (zh)
ES (1) ES2347535T3 (zh)
WO (1) WO2004043497A1 (zh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100563812C (zh) * 2006-03-22 2009-12-02 上海化工研究院 一种可制备多种氟标试剂的化学合成装置
TW200808795A (en) 2006-05-19 2008-02-16 Nihon Mediphysics Co Ltd Novel compound having affinity for amyloid
EP2029182A2 (en) 2006-06-21 2009-03-04 GE Healthcare AS Stabilisation of radiopharmaceutical precursors
EP2042501B1 (en) 2006-06-21 2017-04-12 Nihon Medi-Physics Co., Ltd. Compound having affinity for amyloid
ES2371682T3 (es) 2006-11-30 2012-01-09 Nihon Medi-Physics Co., Ltd. Nuevo compuesto que tiene afinidad por amiloide.
EP2106808B1 (en) 2006-12-21 2018-02-21 Nihon Medi-Physics Co., Ltd. Radioactive diagnostic imaging agent comprising 1-amino-3-[18f]fluorocyclobutanecarboxylic acid
ES2421886T3 (es) 2007-02-13 2013-09-06 Nihon Mediphysics Co Ltd Método para producción de un agente de representación de imágenes de diagnóstico por radiación
US20100254902A1 (en) * 2007-11-07 2010-10-07 Jan Van Den Bos Stabilization of radiopharmaceuticals
EA022897B1 (ru) 2010-06-04 2016-03-31 Пирамаль Имэджинг Са СПОСОБ ПОЛУЧЕНИЯ F-18 МЕЧЕНЫХ Аβ ЛИГАНДОВ
EP2603243B1 (en) 2010-08-13 2020-02-19 Siemens Medical Solutions USA, Inc. Formulation, apparatus and method for stabilizing radiopharmaceuticals
MX363538B (es) 2010-12-29 2019-03-27 Ge Healthcare Ltd Solucion de eluyente.
PL2793954T3 (pl) 2011-12-21 2021-04-06 Ge Healthcare Limited KOMPOZYCJE 18F-FLUCYKLOWINY W BUFORACH CYTRYNlANOWYCH
GB201322456D0 (en) * 2013-12-18 2014-02-05 Ge Healthcare Ltd Radiotracer compositions and methods
KR101633250B1 (ko) 2014-05-30 2016-06-24 성균관대학교산학협력단 방사성 화합물 합성장치
KR101642091B1 (ko) 2014-05-30 2016-07-22 성균관대학교산학협력단 방사성 화합물 합성장치 및 합성방법
KR101668724B1 (ko) 2014-05-30 2016-10-24 성균관대학교산학협력단 방사성 화합물 합성모듈
WO2017014599A1 (ko) * 2015-07-22 2017-01-26 주식회사 씨코헬스케어 [18f]플루오로-도파의 방사화학적 순도를 안정화시키는 조성물 및 이의 제조방법
CN107198780A (zh) * 2016-03-18 2017-09-26 南京江原安迪科正电子研究发展有限公司 放射性药物组合物及其制备方法、应用
GB202005282D0 (en) 2020-04-09 2020-05-27 Blue Earth Diagnostics Ltd Pharmaceutical Formulations

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MC2260A1 (fr) 1990-06-18 1993-04-26 Dow Chemical Co Formulations de produits radiopharmaceutiques,leur methode d'administration et leur procede de preparation
DK0600992T3 (da) 1991-08-29 2000-10-09 Mallinckrodt Medical Inc Anvendelse af gentissyre eller gentisylalkohol til stabilisering af radiomærkede peptider og proteiner
US6066309A (en) 1996-02-02 2000-05-23 Rhomed Incorporated Post-labeling stabilization of radiolabeled proteins and peptides
JP3133251B2 (ja) * 1996-03-29 2001-02-05 エヌケ−ケ−プラント建設株式会社 陽イオン交換樹脂カラム上で、溶媒除去と加水分解反応を同時に行うｆｄｇ合成装置
JP3279914B2 (ja) * 1996-03-29 2002-04-30 エヌケ−ケ−プラント建設株式会社 オンカラムｆｄｇ合成装置
JP3133252B2 (ja) * 1996-03-29 2001-02-05 エヌケ−ケ−プラント建設株式会社 三方切り替え活栓を組み込んだｆｄｇ合成装置
US5932178A (en) 1996-03-29 1999-08-03 Nkk Plant Engineering Corporation FDG synthesizer using columns
JP3133253B2 (ja) * 1996-03-29 2001-02-05 エヌケ−ケ−プラント建設株式会社 標識反応および加水分解反応をカラムで行うｆｄｇ合成装置
JP3133250B2 (ja) * 1996-03-29 2001-02-05 エヌケ−ケ−プラント建設株式会社 使い捨てカートリッジを使用するｆｄｇ合成装置
US6027710A (en) 1996-09-18 2000-02-22 Nihon Medi-Physiscs Co., Ltd. Radiation-protecting agent
AU2001271248A1 (en) * 2000-04-28 2001-11-12 Duke University 18f-labeled choline analogs
AU2002218751A1 (en) * 2000-07-06 2002-01-21 Bristol-Myers Squibb Pharma Company Stable radiopharmaceutical compositions
CN2468490Y (zh) * 2000-09-25 2002-01-02 杜宜奎 氟－18标记药物生产装置
HUP0400027A3 (en) * 2001-02-23 2006-01-30 Bristol Myers Squibb Pharma Co Labeled macrophage scavenger receptor antagonosts for imaging atherosclerosis and vulnerable plaque
GB0115927D0 (en) * 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase nucleophilic fluorination

Also Published As

Publication number Publication date
ATE473019T1 (de) 2010-07-15
KR20060052653A (ko) 2006-05-19
EP2229957A3 (en) 2010-10-06
KR101001300B1 (ko) 2010-12-14
EP2229957A2 (en) 2010-09-22
JP2006505610A (ja) 2006-02-16
AU2002337926B8 (en) 2008-02-28
BR0215913A (pt) 2005-08-09
CN1694733A (zh) 2005-11-09
CN100478035C (zh) 2009-04-15
WO2004043497A1 (en) 2004-05-27
EP1560601A1 (en) 2005-08-10
AU2002337926B2 (en) 2008-01-31
AU2002337926A1 (en) 2004-06-03
DE60236971D1 (de) 2010-08-19
EP1560601B1 (en) 2010-07-07

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