ES2307502T3 - Composicion y procedimiento para modular la interaccion entre celulas dentrificas y linfocitos t. - Google Patents

Composicion y procedimiento para modular la interaccion entre celulas dentrificas y linfocitos t. Download PDF

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Publication number
ES2307502T3
ES2307502T3 ES00921181T ES00921181T ES2307502T3 ES 2307502 T3 ES2307502 T3 ES 2307502T3 ES 00921181 T ES00921181 T ES 00921181T ES 00921181 T ES00921181 T ES 00921181T ES 2307502 T3 ES2307502 T3 ES 2307502T3
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Prior art keywords
cells
sign
antibody
icam
lymphocytes
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Expired - Lifetime
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ES00921181T
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English (en)
Spanish (es)
Inventor
Carl Gustav Figdor
Teunis Bernard Herman Geijtenbeek
Yvette Van Kooyk
Ruurd Torensma
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Radboud Universiteit Nijmegen
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Radboud Universiteit Nijmegen
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • AIDS & HIV (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
ES00921181T 1999-04-19 2000-04-19 Composicion y procedimiento para modular la interaccion entre celulas dentrificas y linfocitos t. Expired - Lifetime ES2307502T3 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP19990201204 EP1046651A1 (en) 1999-04-19 1999-04-19 Composition and method for modulating dendritic cell-T interaction
EP99201204 1999-04-19
US17692400P 2000-01-20 2000-01-20
US176924P 2000-01-20
EP00921181A EP1086137B1 (en) 1999-04-19 2000-04-19 Composition and method for modulating dendritic cell-t cell interaction
PCT/NL2000/000253 WO2000063251A1 (en) 1999-04-19 2000-04-19 Composition and method for modulating dendritic cell-t cell interaction

Publications (1)

Publication Number Publication Date
ES2307502T3 true ES2307502T3 (es) 2008-12-01

Family

ID=8240111

Family Applications (2)

Application Number Title Priority Date Filing Date
ES00921181T Expired - Lifetime ES2307502T3 (es) 1999-04-19 2000-04-19 Composicion y procedimiento para modular la interaccion entre celulas dentrificas y linfocitos t.
ES04078220T Expired - Lifetime ES2346877T3 (es) 1999-04-19 2000-04-19 Composicion y procedimiento para modular la interaccion de las celulas t y las celulas dendriticas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES04078220T Expired - Lifetime ES2346877T3 (es) 1999-04-19 2000-04-19 Composicion y procedimiento para modular la interaccion de las celulas t y las celulas dendriticas.

Country Status (13)

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US (4) US7148329B1 (enExample)
EP (3) EP1046651A1 (enExample)
JP (2) JP4989820B2 (enExample)
KR (3) KR100952883B1 (enExample)
AT (2) ATE472558T1 (enExample)
AU (1) AU776317B2 (enExample)
CA (1) CA2330231C (enExample)
DE (2) DE60039151D1 (enExample)
DK (2) DK1516881T3 (enExample)
ES (2) ES2307502T3 (enExample)
NZ (1) NZ508723A (enExample)
PT (2) PT1516881E (enExample)
WO (1) WO2000063251A1 (enExample)

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Also Published As

Publication number Publication date
EP1046651A1 (en) 2000-10-25
KR20080098678A (ko) 2008-11-11
HK1036285A1 (en) 2001-12-28
JP5363432B2 (ja) 2013-12-11
AU776317B2 (en) 2004-09-02
US8105599B2 (en) 2012-01-31
KR100952883B1 (ko) 2010-04-16
US20050118168A1 (en) 2005-06-02
JP2003502283A (ja) 2003-01-21
DE60039151D1 (de) 2008-07-24
EP1516881B1 (en) 2010-06-30
JP4989820B2 (ja) 2012-08-01
ATE398140T1 (de) 2008-07-15
EP1516881A2 (en) 2005-03-23
WO2000063251A1 (en) 2000-10-26
ATE472558T1 (de) 2010-07-15
NZ508723A (en) 2003-12-19
EP1516881A3 (en) 2005-08-31
PT1086137E (pt) 2008-09-09
CA2330231A1 (en) 2000-10-26
DK1086137T3 (da) 2008-10-27
EP1086137B1 (en) 2008-06-11
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CA2330231C (en) 2013-07-16
DE60044621D1 (de) 2010-08-12
EP1086137A1 (en) 2001-03-28
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AU4152600A (en) 2000-11-02
US20080160041A1 (en) 2008-07-03
US20050220804A1 (en) 2005-10-06
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