PT1516881E - Composição e método para modular a interacção célula dendrítica-célula t - Google Patents
Composição e método para modular a interacção célula dendrítica-célula t Download PDFInfo
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- PT1516881E PT1516881E PT04078220T PT04078220T PT1516881E PT 1516881 E PT1516881 E PT 1516881E PT 04078220 T PT04078220 T PT 04078220T PT 04078220 T PT04078220 T PT 04078220T PT 1516881 E PT1516881 E PT 1516881E
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- Prior art keywords
- leu
- gin
- glu
- cells
- cag
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2317/00—Immunoglobulins specific features
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| EP (3) | EP1046651A1 (enExample) |
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| EP1046651A1 (en) * | 1999-04-19 | 2000-10-25 | Koninklijke Universiteit Nijmegen | Composition and method for modulating dendritic cell-T interaction |
| US6515124B2 (en) * | 2000-02-09 | 2003-02-04 | Hoffman-La Roche Inc. | Dehydroamino acids |
| US7560534B2 (en) * | 2000-05-08 | 2009-07-14 | Celldex Research Corporation | Molecular conjugates comprising human monoclonal antibodies to dendritic cells |
| KR100643818B1 (ko) * | 2000-05-08 | 2006-11-10 | 셀덱스 쎄라퓨틱스, 인크. | 수상세포에 대한 인간 모노클로날 항체 |
| EP1339830A2 (en) * | 2000-12-21 | 2003-09-03 | Stichting Katholieke Universiteit | Method for modulating the binding activity of a novel icam-3 binding receptor on sinusoidal endothelial cells in liver and lymph nodes |
| US20030013081A1 (en) | 2001-06-26 | 2003-01-16 | Olson William C. | Uses of DC-SIGN and DC-SIGNR for inhibiting hepatitis C virus infection |
| US7022323B2 (en) | 2001-06-26 | 2006-04-04 | Progenics Pharmaceuticals, Inc. | Uses of DC-SIGN and DC-SIGNR for inhibiting hepatitis C virus infection |
| ES2197826B1 (es) * | 2002-06-21 | 2005-04-01 | Consejo Superior De Investigaciones Cientificas | Compuesto terapeutico frente a la infeccion por leishmania y su uso. |
| US7541032B2 (en) * | 2002-09-20 | 2009-06-02 | Stichting Katholieke Universiteit | Antigen uptake receptor for Candida albicans on dendritic cells |
| US7691591B2 (en) * | 2002-09-20 | 2010-04-06 | Stichting Katholieke Universiteit | Methods of identifying and isolating cells expressing DC-sign |
| US20040146948A1 (en) * | 2002-10-18 | 2004-07-29 | Centenary Institute Of Cancer Medicine And Cell Biology | Compositions and methods for targeting antigen-presenting cells with antibody single-chain variable region fragments |
| US7427469B2 (en) | 2002-11-05 | 2008-09-23 | Institut Pasteur | Method of treating cytomegalovirus with DC-SIGN blockers |
| BR0315975A (pt) * | 2002-11-05 | 2005-09-20 | Pasteur Institut | Usos de uma quantidade de um modulador e de um bloqueador de dc-sign, composição farmacêutica, métodos para identificar um modulador e um bloqueador de dc-sign, bloqueador de dc-sign isolado, e, método para alvejar uma molécula objeto a uma célula que expressa um receptore de dc-sign |
| EP1417965A1 (en) * | 2002-11-07 | 2004-05-12 | Vereniging Voor Christelijk Wetenschappelijk Onderwijs | C-type lectin binding molecules, identification and uses thereof |
| EP1594533B1 (en) | 2003-01-31 | 2012-04-11 | Celldex Research Corporation | Antibody vaccine conjugates and uses therefor |
| US9259459B2 (en) | 2003-01-31 | 2016-02-16 | Celldex Therapeutics Inc. | Antibody vaccine conjugates and uses therefor |
| AU2011211337B2 (en) * | 2003-10-16 | 2014-10-02 | Cancure Limited | Immunomodulating compositions and uses therefor |
| EP2591786B1 (en) * | 2003-10-16 | 2017-04-12 | Cancure Limited | Immunomodulating compositions and uses therefor |
| EP1699487A4 (en) * | 2003-12-15 | 2009-07-08 | Alexion Pharma Inc | NEW ANTI-DC-SIGN ANTIBODIES |
| EP1761248B1 (en) | 2004-03-19 | 2012-05-23 | Rodos BioTarget GmbH | Carbohydrate-derivatized liposomes for targeting cellular carbohydrate recognition domains of ctl/ctld lectins, and intracellular delivery of therapeutically active compounds |
| DK1765294T3 (da) * | 2004-05-12 | 2008-11-10 | Baxter Int | Nukleinsyremikrokugler samt deres fremstilling og afgivelse |
| EP1758558B1 (en) * | 2004-05-12 | 2013-10-16 | Baxter International Inc. | Oligonucleotide-containing microspheres, their use for the manufacture of a medicament for treating diabetes type 1 |
| AU2006252406B2 (en) | 2005-06-01 | 2012-05-17 | California Institute Of Technology | Method of targeted gene delivery using viral vectors |
| FR2895262B1 (fr) * | 2005-12-22 | 2009-07-17 | Lab Francais Du Fractionnement | Inhibition de la reponse immunitaire anti-fviii |
| AT503387B1 (de) * | 2006-03-27 | 2008-05-15 | Univ Wien | Pharmazeutische zusammensetzung zur vorbeugung von infektionen |
| SG173337A1 (en) | 2006-07-21 | 2011-08-29 | California Inst Of Techn | Targeted gene delivery for dendritic cell vaccination |
| BRPI0807160A2 (pt) | 2007-02-02 | 2018-09-25 | Baylor Res Institute | vacinas baseadas no direcionamento de antígeno ao dcir expresso em células apresentadoras de antígeno |
| TWI422594B (zh) | 2007-02-02 | 2014-01-11 | Baylor Res Inst | 經由樹狀細胞去唾液酸糖蛋白受體（ｄｃ-ａｓｇｐｒ）接合抗原呈現細胞之藥劑 |
| ES2536900T3 (es) * | 2007-02-02 | 2015-05-29 | Baylor Research Institute | Antígenos multivariables en complejo con anticuerpo monoclonal humanizado de dirección |
| BRPI0815848A2 (pt) | 2007-08-30 | 2017-06-06 | The Burnet Inst | composto, linhagem de célula que produz anticorpo estável, composição, métodos para modular uma resposta imune em um indivíduo e para tratar e/ou prevenir uma doença, usos de um composto e/ou uma composição e de células dendríticas ou precursores das mesmas, métodos para enriquecer e detectar células dendríticas ou um subconjunto ou precursores das mesmas, polipeptídeo, polinucleotídeo vetor, célula hospedeira, planta transgênica, animal não humano transgênico, extrato, processo para preparar um composto ou um polipeptídeo, população enriquecida de células dendríticas e/ou precursores das mesmas, população de célula dendrítica expandida e/ou precursores das mesmas, métodos para identificar uma molécula que se liga a um polipeptídeo e para triar quanto a um composto que se liga a um polipeptídeo, uso de um polipeptídeo, um polinucleotídeo, um vetor, uma célula hospedeira, uma planta transgênica, um extrato, uma população de célula e/ou uma composição, método para produzir um composto, e, kit. |
| EP2207798A2 (en) | 2007-10-29 | 2010-07-21 | Virginia Tech Intellectual Properties, Inc. | Porcine dc-sign, icam-3 and lsectin and uses thereof |
| BRPI0820270A2 (pt) | 2007-11-07 | 2015-06-16 | Celldex Therapeutics Inc | Anticorpo monoclonal, vetor de expressão, célula, conjugado molecular, composição, uso da composição, método para detectar a presença ou ausência de dec-205 em uma amostra biológica, e, uso de um conjugado molecular. |
| WO2011011584A1 (en) | 2009-07-24 | 2011-01-27 | Immune Design Corp | Lentiviral vectors pseudotyped with a sindbis virus envelope glycoprotein |
| WO2011055550A1 (ja) * | 2009-11-05 | 2011-05-12 | 国立大学法人大阪大学 | 自己免疫疾患又はアレルギー治療剤とそのスクリーニング方法 |
| JP5690132B2 (ja) | 2010-06-17 | 2015-03-25 | 株式会社マーレ フィルターシステムズ | エンジンの換気システム |
| US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| AU2011289579B2 (en) | 2010-08-10 | 2016-11-17 | Ecole Polytechnique Federale De Lausanne | Erythrocyte-binding therapeutics |
| EP2831095B1 (en) | 2012-03-30 | 2018-11-28 | Immune Design Corp. | Lentiviral vector particles having improved transduction efficiency for cells expressing dc-sign |
| US8323662B1 (en) | 2012-03-30 | 2012-12-04 | Immune Design Corp. | Methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein |
| US9713635B2 (en) | 2012-03-30 | 2017-07-25 | Immune Design Corp. | Materials and methods for producing improved lentiviral vector particles |
| EP3549605A1 (en) * | 2012-04-04 | 2019-10-09 | Vaxform LLC | Adjuvant system for oral vaccine administration |
| EP2897641B1 (en) * | 2012-09-18 | 2018-07-18 | University of Washington through its Center for Commercialization | Compositions and methods for antigen targeting to cd180 |
| US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
| LT3107563T (lt) | 2014-02-21 | 2021-07-12 | Ecole Polytechnique Fédérale De Lausanne (Epfl) Epfl-Tto | Gliko-nukreipiantys terapiniai agenai |
| US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| CN106659774A (zh) | 2014-05-16 | 2017-05-10 | 贝勒研究院 | 用于治疗自身免疫和炎性病症的方法和组合物 |
| US10688178B2 (en) | 2015-06-30 | 2020-06-23 | Osaka University | AntiPlexin A1 agonist antibody |
| CN108210503A (zh) * | 2016-12-10 | 2018-06-29 | 高尚先 | 甘露糖在用于提高Treg细胞数量及其Foxp3因子表达水平的新用途 |
| US11253579B2 (en) | 2017-06-16 | 2022-02-22 | The University Of Chicago | Compositions and methods for inducing immune tolerance |
| EA202092723A1 (ru) | 2018-05-09 | 2021-04-09 | Зе Юниверсити Оф Чикаго | Композиции и способы, касающиеся иммунной толерантности |
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| EP0984984A2 (en) * | 1997-06-03 | 2000-03-15 | Sagami Chemical Research Center | HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS |
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| EP1046651A1 (en) * | 1999-04-19 | 2000-10-25 | Koninklijke Universiteit Nijmegen | Composition and method for modulating dendritic cell-T interaction |
| IL147902A0 (en) * | 1999-08-12 | 2002-08-14 | Agensys Inc | C-type lectin transmembrane antigen expressed in human prostate cancer and uses thereof |
| EP1339830A2 (en) | 2000-12-21 | 2003-09-03 | Stichting Katholieke Universiteit | Method for modulating the binding activity of a novel icam-3 binding receptor on sinusoidal endothelial cells in liver and lymph nodes |
| US20030232745A1 (en) | 2001-06-26 | 2003-12-18 | Olson William C. | Uses of DC-sign and DC-Signr for inhibiting hepatitis C virus infection |
| US7022323B2 (en) * | 2001-06-26 | 2006-04-04 | Progenics Pharmaceuticals, Inc. | Uses of DC-SIGN and DC-SIGNR for inhibiting hepatitis C virus infection |
| EP1542354B1 (en) * | 2003-12-09 | 2021-02-03 | Synergy Microwave Corporation | Integrated ultra low noise microwave wideband push-push vco |
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