DK1086137T3 - Sammensætning og fremgangsmåde til at modulere dendritisk T-celle cellevekselvirkning - Google Patents
Sammensætning og fremgangsmåde til at modulere dendritisk T-celle cellevekselvirkningInfo
- Publication number
- DK1086137T3 DK1086137T3 DK00921181T DK00921181T DK1086137T3 DK 1086137 T3 DK1086137 T3 DK 1086137T3 DK 00921181 T DK00921181 T DK 00921181T DK 00921181 T DK00921181 T DK 00921181T DK 1086137 T3 DK1086137 T3 DK 1086137T3
- Authority
- DK
- Denmark
- Prior art keywords
- cells
- cell
- antibody
- sign
- clumping
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000008611 intercellular interaction Effects 0.000 title 1
- 210000004443 dendritic cell Anatomy 0.000 abstract 7
- 210000004027 cell Anatomy 0.000 abstract 5
- 108090000342 C-Type Lectins Proteins 0.000 abstract 2
- 102000003930 C-Type Lectins Human genes 0.000 abstract 2
- 108010037897 DC-specific ICAM-3 grabbing nonintegrin Proteins 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 108010030351 DEC-205 receptor Proteins 0.000 abstract 1
- 102000006481 HIV Receptors Human genes 0.000 abstract 1
- 108010083930 HIV Receptors Proteins 0.000 abstract 1
- 108010064600 Intercellular Adhesion Molecule-3 Proteins 0.000 abstract 1
- 102100037871 Intercellular adhesion molecule 3 Human genes 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 230000006052 T cell proliferation Effects 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000000842 anti-protozoal effect Effects 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000003904 antiprotozoal agent Substances 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 229960001438 immunostimulant agent Drugs 0.000 abstract 1
- 239000003022 immunostimulating agent Substances 0.000 abstract 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 1
- 229960003444 immunosuppressant agent Drugs 0.000 abstract 1
- 230000001861 immunosuppressant effect Effects 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 230000003834 intracellular effect Effects 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000002609 medium Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- AIDS & HIV (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19990201204 EP1046651A1 (en) | 1999-04-19 | 1999-04-19 | Composition and method for modulating dendritic cell-T interaction |
| US17692400P | 2000-01-20 | 2000-01-20 | |
| PCT/NL2000/000253 WO2000063251A1 (en) | 1999-04-19 | 2000-04-19 | Composition and method for modulating dendritic cell-t cell interaction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1086137T3 true DK1086137T3 (da) | 2008-10-27 |
Family
ID=8240111
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00921181T DK1086137T3 (da) | 1999-04-19 | 2000-04-19 | Sammensætning og fremgangsmåde til at modulere dendritisk T-celle cellevekselvirkning |
| DK04078220.3T DK1516881T3 (da) | 1999-04-19 | 2000-04-19 | Sammensætning og fremgangsmåde til modulering af dendritcelle-T-celle-interaktioner |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04078220.3T DK1516881T3 (da) | 1999-04-19 | 2000-04-19 | Sammensætning og fremgangsmåde til modulering af dendritcelle-T-celle-interaktioner |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US7148329B1 (enExample) |
| EP (3) | EP1046651A1 (enExample) |
| JP (2) | JP4989820B2 (enExample) |
| KR (3) | KR100923340B1 (enExample) |
| AT (2) | ATE398140T1 (enExample) |
| AU (1) | AU776317B2 (enExample) |
| CA (1) | CA2330231C (enExample) |
| DE (2) | DE60044621D1 (enExample) |
| DK (2) | DK1086137T3 (enExample) |
| ES (2) | ES2346877T3 (enExample) |
| NZ (1) | NZ508723A (enExample) |
| PT (2) | PT1086137E (enExample) |
| WO (1) | WO2000063251A1 (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1046651A1 (en) | 1999-04-19 | 2000-10-25 | Koninklijke Universiteit Nijmegen | Composition and method for modulating dendritic cell-T interaction |
| US6515124B2 (en) * | 2000-02-09 | 2003-02-04 | Hoffman-La Roche Inc. | Dehydroamino acids |
| KR100881471B1 (ko) * | 2000-05-08 | 2009-02-05 | 셀덱스 쎄라퓨틱스, 인크. | 수상세포에 대한 인간 모노클로날 항체 |
| US7560534B2 (en) | 2000-05-08 | 2009-07-14 | Celldex Research Corporation | Molecular conjugates comprising human monoclonal antibodies to dendritic cells |
| EP1339830A2 (en) * | 2000-12-21 | 2003-09-03 | Stichting Katholieke Universiteit | Method for modulating the binding activity of a novel icam-3 binding receptor on sinusoidal endothelial cells in liver and lymph nodes |
| US7022323B2 (en) | 2001-06-26 | 2006-04-04 | Progenics Pharmaceuticals, Inc. | Uses of DC-SIGN and DC-SIGNR for inhibiting hepatitis C virus infection |
| US20030013081A1 (en) | 2001-06-26 | 2003-01-16 | Olson William C. | Uses of DC-SIGN and DC-SIGNR for inhibiting hepatitis C virus infection |
| ES2197826B1 (es) * | 2002-06-21 | 2005-04-01 | Consejo Superior De Investigaciones Cientificas | Compuesto terapeutico frente a la infeccion por leishmania y su uso. |
| US7691591B2 (en) | 2002-09-20 | 2010-04-06 | Stichting Katholieke Universiteit | Methods of identifying and isolating cells expressing DC-sign |
| AU2003269389A1 (en) * | 2002-09-20 | 2004-04-08 | Stichting Katholieke Universiteit | Antigen uptake receptor for candida albicans on dendritic cells |
| US20040146948A1 (en) * | 2002-10-18 | 2004-07-29 | Centenary Institute Of Cancer Medicine And Cell Biology | Compositions and methods for targeting antigen-presenting cells with antibody single-chain variable region fragments |
| AU2003301804A1 (en) * | 2002-11-05 | 2004-06-07 | Institut National De La Sante Et De La Recherche Medicale | Dc-sign blockers and their use for preventing or treating viral infections. |
| US7427469B2 (en) | 2002-11-05 | 2008-09-23 | Institut Pasteur | Method of treating cytomegalovirus with DC-SIGN blockers |
| EP1417965A1 (en) * | 2002-11-07 | 2004-05-12 | Vereniging Voor Christelijk Wetenschappelijk Onderwijs | C-type lectin binding molecules, identification and uses thereof |
| CA2514979A1 (en) | 2003-01-31 | 2004-09-02 | Celldex Therapeutics, Inc. | Antibody vaccine conjugates and uses therefor |
| US9259459B2 (en) | 2003-01-31 | 2016-02-16 | Celldex Therapeutics Inc. | Antibody vaccine conjugates and uses therefor |
| AU2011211337B2 (en) * | 2003-10-16 | 2014-10-02 | Cancure Limited | Immunomodulating compositions and uses therefor |
| AU2004281080A1 (en) | 2003-10-16 | 2005-04-28 | Stephen John Ralph | Immunomodulating compositions and uses therefor |
| WO2005058244A2 (en) | 2003-12-15 | 2005-06-30 | Alexion Pharmaceuticals, Inc. | Novel anti-dc-sign antibodies |
| WO2005092288A1 (en) | 2004-03-19 | 2005-10-06 | Let There Be Hope Medical Research Institute | Carbohydrate-derivatized liposomes for targeting cellular carbohydrate recognition domains of ctl/ctld lectins, and intracellular delivery of therapeutically active compounds |
| US7884085B2 (en) * | 2004-05-12 | 2011-02-08 | Baxter International Inc. | Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes |
| EP2072040B1 (en) * | 2004-05-12 | 2013-05-01 | Baxter International Inc. | Therapeutic use of nucleic acid micropheres |
| US20070020238A1 (en) | 2005-06-01 | 2007-01-25 | David Baltimore | Method of targeted gene delivery using viral vectors |
| FR2895262B1 (fr) * | 2005-12-22 | 2009-07-17 | Lab Francais Du Fractionnement | Inhibition de la reponse immunitaire anti-fviii |
| AT503387B1 (de) * | 2006-03-27 | 2008-05-15 | Univ Wien | Pharmazeutische zusammensetzung zur vorbeugung von infektionen |
| BRPI0714495B8 (pt) * | 2006-07-21 | 2021-05-25 | California Inst Of Techn | lentivírus deficiente para replicação recombinante pseudotipado |
| KR20090114430A (ko) * | 2007-02-02 | 2009-11-03 | 베일러 리서치 인스티튜트 | 항원-제시 세포 상에서 발현된 ｄｃｉｒ에 대한 항원 표적화에 기초한 백신 |
| TWI422594B (zh) | 2007-02-02 | 2014-01-11 | Baylor Res Inst | 經由樹狀細胞去唾液酸糖蛋白受體（ｄｃ-ａｓｇｐｒ）接合抗原呈現細胞之藥劑 |
| WO2008097817A2 (en) * | 2007-02-02 | 2008-08-14 | Baylor Research Institute | Multivariable antigens complexed with targeting humanized monoclonal antibody |
| BRPI0815848A2 (pt) * | 2007-08-30 | 2017-06-06 | The Burnet Inst | composto, linhagem de célula que produz anticorpo estável, composição, métodos para modular uma resposta imune em um indivíduo e para tratar e/ou prevenir uma doença, usos de um composto e/ou uma composição e de células dendríticas ou precursores das mesmas, métodos para enriquecer e detectar células dendríticas ou um subconjunto ou precursores das mesmas, polipeptídeo, polinucleotídeo vetor, célula hospedeira, planta transgênica, animal não humano transgênico, extrato, processo para preparar um composto ou um polipeptídeo, população enriquecida de células dendríticas e/ou precursores das mesmas, população de célula dendrítica expandida e/ou precursores das mesmas, métodos para identificar uma molécula que se liga a um polipeptídeo e para triar quanto a um composto que se liga a um polipeptídeo, uso de um polipeptídeo, um polinucleotídeo, um vetor, uma célula hospedeira, uma planta transgênica, um extrato, uma população de célula e/ou uma composição, método para produzir um composto, e, kit. |
| AU2008319384A1 (en) | 2007-10-29 | 2009-05-07 | Virginia Tech Intellectual Properties, Inc. | Porcine DC-SIGN , ICAM-3 and LSECtin and uses thereof |
| SG187482A1 (en) | 2007-11-07 | 2013-02-28 | Celldex Therapeutics Inc | Antibodies that bind human dendritic and epithelial cell 205 (dec-205) |
| EP2770061B1 (en) | 2009-07-24 | 2018-10-24 | Immune Design Corp. | Non-integrating lentiviral vectors |
| JP5888728B2 (ja) * | 2009-11-05 | 2016-03-22 | 国立大学法人大阪大学 | 自己免疫疾患又はアレルギー治療剤とそのスクリーニング方法 |
| JP5690132B2 (ja) | 2010-06-17 | 2015-03-25 | 株式会社マーレ フィルターシステムズ | エンジンの換気システム |
| CN108117586A (zh) | 2010-08-10 | 2018-06-05 | 洛桑聚合联合学院 | 红细胞结合性治疗剂 |
| US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| EP3480316B1 (en) | 2012-03-30 | 2022-09-14 | Immune Design Corp. | Lentiviral vector particles having improved transduction efficiency for cells expressing dc-sign |
| US9713635B2 (en) | 2012-03-30 | 2017-07-25 | Immune Design Corp. | Materials and methods for producing improved lentiviral vector particles |
| US8323662B1 (en) | 2012-03-30 | 2012-12-04 | Immune Design Corp. | Methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein |
| DK2833914T3 (en) * | 2012-04-04 | 2019-03-11 | Vaxform Llc | ADMINISTRATIVE SYSTEM FOR ORAL VACCINE ADMINISTRATION |
| US10196614B2 (en) * | 2012-09-18 | 2019-02-05 | University Of Washington Through Its Center For Commercialization | Compositions and methods for antigen targeting to CD180 |
| US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| AU2015233084B2 (en) | 2014-02-21 | 2020-12-17 | Anokion Sa | Glycotargeting therapeutics |
| US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
| US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| CA3185180A1 (en) | 2014-05-16 | 2015-11-19 | Baylor Research Institute | Methods and compositions for treating autoimmune and inflammatory conditions |
| EP3318577A4 (en) | 2015-06-30 | 2019-01-23 | Osaka University | ANTIPLEXIN A1 AGONISTANTIKÖRPER |
| CN108210503A (zh) * | 2016-12-10 | 2018-06-29 | 高尚先 | 甘露糖在用于提高Treg细胞数量及其Foxp3因子表达水平的新用途 |
| US11253579B2 (en) | 2017-06-16 | 2022-02-22 | The University Of Chicago | Compositions and methods for inducing immune tolerance |
| CN112384239A (zh) | 2018-05-09 | 2021-02-19 | 芝加哥大学 | 影响免疫耐受的组合物和方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US891992A (en) | 1907-06-27 | 1908-06-30 | Henry Hess | Method of forming conically-shaped ends upon rollers and other objects. |
| US5332567A (en) * | 1989-08-24 | 1994-07-26 | Immunomedics | Detection and treatment of infections with immunoconjugates |
| US6248332B1 (en) * | 1990-10-05 | 2001-06-19 | Medarex, Inc. | Targeted immunostimulation with bispecific reagents |
| MX9204131A (es) * | 1991-07-16 | 1993-04-01 | Bristol Myers Squibb Co | Proteina receptora de gp120. |
| WO1995003234A1 (en) | 1993-07-22 | 1995-02-02 | Precision Valve Corporation | Multi-directional actuation overcap |
| US6084067A (en) | 1993-07-26 | 2000-07-04 | Dana-Farber Cancer Institute | CTLA4/CD28 ligands and uses therefor |
| AUPM322393A0 (en) * | 1993-12-24 | 1994-01-27 | Austin Research Institute, The | Mucin carbohydrate compounds and their use in immunotherapy |
| EP0759782A1 (en) | 1994-05-26 | 1997-03-05 | Innogenetics N.V. | New methods and compounds for the selective modulation of antigen-specific t-cell responsiveness |
| US5548275A (en) * | 1995-01-23 | 1996-08-20 | Shambayati; Ali | Alarm system for enclosing and protecting an area |
| US5643786A (en) | 1995-01-27 | 1997-07-01 | The United States Of America As Represented By The Department Of Health And Human Services | Method for isolating dendritic cells |
| EP0808366A1 (en) * | 1995-01-31 | 1997-11-26 | The Rockefeller University | IDENTIFICATION OF DEC, (DENTRITIC AND EPITHELIAL CELLS, 205 kDa), A RECEPTOR WITH C-TYPE LECTIN DOMAINS, NUCLEIC ACIDS ENCODING DEC, AND USES THEREOF |
| US5871964A (en) * | 1996-07-15 | 1999-02-16 | Incyte Pharmaceuticals, Inc. | Human C-type lectin |
| US6046158A (en) * | 1996-12-20 | 2000-04-04 | Board Of Regents The University Of Texas Systems | Unique dendritic cell-associated C-type lectins, dectin-1 and dectin-2; compositions and uses thereof |
| US5935813A (en) * | 1997-03-20 | 1999-08-10 | Incyte Pharmaceuticals, Inc. | Human pancreatitis-associated protein |
| AU7172198A (en) * | 1997-04-29 | 1998-11-24 | Incyte Pharmaceuticals, Inc. | Human c-type lectin |
| JP2002512524A (ja) | 1997-06-03 | 2002-04-23 | 財団法人相模中央化学研究所 | 膜貫通ドメインを有するヒト蛋白質及びそれをコードするｄｎａ |
| US6273443B1 (en) * | 1998-06-01 | 2001-08-14 | Sunrise Medical Hhg Inc. | Universal elevating leg rest assembly |
| EP1046651A1 (en) * | 1999-04-19 | 2000-10-25 | Koninklijke Universiteit Nijmegen | Composition and method for modulating dendritic cell-T interaction |
| ATE486938T1 (de) * | 1999-08-12 | 2010-11-15 | Agensys Inc | C-typ-lektin-transmembran-antigen, das in menschlichem prostatakrebs exprimiert wird, und verwendungen dieses antigens |
| EP1339830A2 (en) | 2000-12-21 | 2003-09-03 | Stichting Katholieke Universiteit | Method for modulating the binding activity of a novel icam-3 binding receptor on sinusoidal endothelial cells in liver and lymph nodes |
| US20030232745A1 (en) * | 2001-06-26 | 2003-12-18 | Olson William C. | Uses of DC-sign and DC-Signr for inhibiting hepatitis C virus infection |
| US7022323B2 (en) * | 2001-06-26 | 2006-04-04 | Progenics Pharmaceuticals, Inc. | Uses of DC-SIGN and DC-SIGNR for inhibiting hepatitis C virus infection |
| CA2548317C (en) * | 2003-12-09 | 2009-04-21 | Synergy Microwave Corporation | User-definable thermal drift voltage control oscillator |
-
1999
- 1999-04-19 EP EP19990201204 patent/EP1046651A1/en not_active Withdrawn
-
2000
- 2000-04-19 CA CA2330231A patent/CA2330231C/en not_active Expired - Fee Related
- 2000-04-19 DE DE60044621T patent/DE60044621D1/de not_active Expired - Lifetime
- 2000-04-19 DK DK00921181T patent/DK1086137T3/da active
- 2000-04-19 ES ES04078220T patent/ES2346877T3/es not_active Expired - Lifetime
- 2000-04-19 AT AT00921181T patent/ATE398140T1/de active
- 2000-04-19 WO PCT/NL2000/000253 patent/WO2000063251A1/en not_active Ceased
- 2000-04-19 US US09/719,961 patent/US7148329B1/en not_active Expired - Fee Related
- 2000-04-19 EP EP04078220A patent/EP1516881B1/en not_active Expired - Lifetime
- 2000-04-19 PT PT00921181T patent/PT1086137E/pt unknown
- 2000-04-19 KR KR1020077020353A patent/KR100923340B1/ko not_active Expired - Fee Related
- 2000-04-19 DK DK04078220.3T patent/DK1516881T3/da active
- 2000-04-19 JP JP2000612337A patent/JP4989820B2/ja not_active Expired - Fee Related
- 2000-04-19 KR KR1020007014459A patent/KR20010071530A/ko not_active Ceased
- 2000-04-19 NZ NZ508723A patent/NZ508723A/en not_active IP Right Cessation
- 2000-04-19 EP EP00921181A patent/EP1086137B1/en not_active Expired - Lifetime
- 2000-04-19 AU AU41526/00A patent/AU776317B2/en not_active Ceased
- 2000-04-19 AT AT04078220T patent/ATE472558T1/de active
- 2000-04-19 ES ES00921181T patent/ES2307502T3/es not_active Expired - Lifetime
- 2000-04-19 PT PT04078220T patent/PT1516881E/pt unknown
- 2000-04-19 KR KR1020087023697A patent/KR100952883B1/ko not_active Expired - Fee Related
- 2000-04-19 DE DE60039151T patent/DE60039151D1/de not_active Expired - Lifetime
-
2003
- 2003-07-23 US US10/625,202 patent/US8105599B2/en not_active Expired - Fee Related
- 2003-07-23 US US10/625,204 patent/US7285642B2/en not_active Expired - Fee Related
-
2007
- 2007-10-22 US US11/977,151 patent/US8058400B2/en not_active Expired - Fee Related
-
2010
- 2010-08-05 JP JP2010176824A patent/JP5363432B2/ja not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1086137T3 (da) | Sammensætning og fremgangsmåde til at modulere dendritisk T-celle cellevekselvirkning | |
| ES2657443T3 (es) | Anticuerpos anti-GITR y usos de los mismos | |
| AU2023200440A1 (en) | Antagonistic anti-tumor necrosis factor receptor superfamily antibodies | |
| MX2012012833A (es) | Cebado cruzado de celulas t cd8 positivas humanos moderada por inmunoreceptores de celulas dendriticas (dcir). | |
| WO2017197347A1 (en) | METHODS FOR SELECTIVE EXPANSION OF γδ T-CELL POPULATIONS AND COMPOSITIONS THEREOF | |
| CN115315446A (zh) | 抗糖-cd44抗体及其用途 | |
| CN113527521A (zh) | 一种抗b7h3嵌合抗原受体及其应用 | |
| KR20190016966A (ko) | 길항성 항-종양 괴사 인자 수용체 슈퍼패밀리 항체 | |
| KR20180099641A (ko) | 세포의 배양 방법 및 이를 위한 키트와 장치 | |
| JPH10179151A (ja) | 二特異的抗体を用いた幹細胞移植における汚染腫瘍細胞の除去 | |
| CN106999556A (zh) | 细胞因子诱导的杀伤细胞的双特异性抗体介导的癌症治疗 | |
| KR20090114466A (ko) | 덱틴-1을 통한 사람 항원제시세포 활성화의 치료학적 적용 | |
| KR20090127886A (ko) | 수지상 세포 렉틴 유사 산화된 ｌｄｌ 수용체-1(ｌｏｘ-1)을 통한 사람 항원제시세포의 활성화 | |
| IL148113A0 (en) | Ovarian cancer cell and myeloma cell surface glycoproteins, antibodies thereto, and uses thereof | |
| JP2013517330A (ja) | 抗ｉｌｔ５抗体およびｉｌｔ５結合抗体断片 | |
| JPWO2020132024A5 (enExample) | ||
| Bezverbnaya et al. | Development of a B-cell maturation antigen-specific T-cell antigen coupler receptor for multiple myeloma | |
| AU2018370120A1 (en) | Methods for selective expansion of d3 yd T-cell populations and compositions thereof | |
| CA3160609A1 (en) | Methods for expanding gamma delta t-cell populations with multivalent agents and compositions thereof | |
| US20210108176A1 (en) | Transduction and expansion of cells | |
| CN118355031A (zh) | 抗糖-lamp1抗体及其用途 | |
| CN116368222A (zh) | 破坏cd28-唾液酸糖苷配体复合物以增强t细胞活化 | |
| Cordero et al. | Interleukin-12-dependent activation of human lymphocyte subsets | |
| CN119215188B (zh) | 抗Trop2抗体和抗5T4抗体-自然杀伤细胞偶联物及其用途 | |
| CN119280420B (zh) | 多特异性偶联物及其应用 |