ES2289544T3 - Oligonucleotido antisentido para inhibir la actividad inhibidora de melanoma mia. - Google Patents
Oligonucleotido antisentido para inhibir la actividad inhibidora de melanoma mia. Download PDFInfo
- Publication number
- ES2289544T3 ES2289544T3 ES04763992T ES04763992T ES2289544T3 ES 2289544 T3 ES2289544 T3 ES 2289544T3 ES 04763992 T ES04763992 T ES 04763992T ES 04763992 T ES04763992 T ES 04763992T ES 2289544 T3 ES2289544 T3 ES 2289544T3
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- Spain
- Prior art keywords
- mia
- bases
- oligonucleotide
- antisense
- oligonucleotides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/312—Phosphonates
- C12N2310/3125—Methylphosphonates
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- C—CHEMISTRY; METALLURGY
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/321—2'-O-R Modification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/322—2'-R Modification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/351—Conjugate
- C12N2310/3513—Protein; Peptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/351—Conjugate
- C12N2310/3515—Lipophilic moiety, e.g. cholesterol
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
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- Rheumatology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03018285 | 2003-08-12 | ||
| EP03018285 | 2003-08-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2289544T3 true ES2289544T3 (es) | 2008-02-01 |
Family
ID=34130073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES04763992T Expired - Lifetime ES2289544T3 (es) | 2003-08-12 | 2004-08-11 | Oligonucleotido antisentido para inhibir la actividad inhibidora de melanoma mia. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7910563B2 (https=) |
| EP (1) | EP1660656B1 (https=) |
| JP (1) | JP4649408B2 (https=) |
| AT (1) | ATE369422T1 (https=) |
| DE (1) | DE602004008085T2 (https=) |
| ES (1) | ES2289544T3 (https=) |
| WO (1) | WO2005014812A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602004008085T2 (de) | 2003-08-12 | 2008-04-24 | Antisense Pharma Gmbh | Antisense-oligonukleotid zur hemmung der melanom-inhibierenden aktivität (mia) |
| CN100562342C (zh) * | 2006-01-17 | 2009-11-25 | 奥林格斯技术有限公司 | 防治流感病毒感染的寡核苷酸药物 |
| EP2580326A1 (en) | 2010-06-11 | 2013-04-17 | Antisense Pharma GmbH | Method for selective oligonucleotide modification |
| ITRM20110134A1 (it) * | 2011-03-22 | 2012-09-23 | Matteo Bordignon | Inibitori di mia (attività inibitoria melanoma) per identificare, prevenire e curare la vitiligine |
| EP3103450A1 (en) * | 2015-06-12 | 2016-12-14 | Friedrich-Alexander-Universität Erlangen-Nürnberg | None-hydrophobic compounds for use in treating metastasis and/or cartilage defect |
| CN105250900A (zh) * | 2015-10-21 | 2016-01-20 | 宋军君 | 一种治疗腰椎间盘突出中药 |
| US9758786B2 (en) | 2016-02-09 | 2017-09-12 | Autotelic, Llc | Compositions and methods for treating pancreatic cancer |
| KR20180103816A (ko) | 2016-02-09 | 2018-09-19 | 오토텔릭 엘엘씨 | 췌장암을 치료하기 위한 조성물과 방법 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0945507A1 (de) * | 1998-03-27 | 1999-09-29 | Boehringer Mannheim Gmbh | Tumorspezifische Expressionskontrollregion und deren Verwendung |
| WO1999065928A2 (en) * | 1998-06-19 | 1999-12-23 | Genzyme Corporation | Polynucleotide population isolated from non-metastatic and metastatic breast tumor tissues |
| EP1133994A1 (en) * | 2000-03-11 | 2001-09-19 | Biognostik Gesellschaft für biomolekulare Diagnostik mbH | A method for reversing the immunosuppressive effects of the Melanoma Inhibitory Activity "MIA" |
| AU2001250572A1 (en) * | 2000-04-07 | 2001-10-23 | Epigenomics Ag | Detection of single nucleotide polymorphisms (snp's) and cytosine-methylations |
| DE602004008085T2 (de) | 2003-08-12 | 2008-04-24 | Antisense Pharma Gmbh | Antisense-oligonukleotid zur hemmung der melanom-inhibierenden aktivität (mia) |
-
2004
- 2004-08-11 DE DE602004008085T patent/DE602004008085T2/de not_active Expired - Lifetime
- 2004-08-11 AT AT04763992T patent/ATE369422T1/de active
- 2004-08-11 US US10/567,879 patent/US7910563B2/en not_active Expired - Fee Related
- 2004-08-11 EP EP04763992A patent/EP1660656B1/en not_active Expired - Lifetime
- 2004-08-11 JP JP2006522977A patent/JP4649408B2/ja not_active Expired - Fee Related
- 2004-08-11 WO PCT/EP2004/008986 patent/WO2005014812A2/en not_active Ceased
- 2004-08-11 ES ES04763992T patent/ES2289544T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1660656B1 (en) | 2007-08-08 |
| WO2005014812A2 (en) | 2005-02-17 |
| JP4649408B2 (ja) | 2011-03-09 |
| EP1660656A2 (en) | 2006-05-31 |
| DE602004008085D1 (de) | 2007-09-20 |
| US20070299022A1 (en) | 2007-12-27 |
| DE602004008085T2 (de) | 2008-04-24 |
| JP2007501621A (ja) | 2007-02-01 |
| WO2005014812A3 (en) | 2005-06-09 |
| ATE369422T1 (de) | 2007-08-15 |
| US7910563B2 (en) | 2011-03-22 |
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