ES2288578T3 - Mezcla para cemento de huesos y agente de contraste de rayos x. - Google Patents
Mezcla para cemento de huesos y agente de contraste de rayos x. Download PDFInfo
- Publication number
- ES2288578T3 ES2288578T3 ES03009377T ES03009377T ES2288578T3 ES 2288578 T3 ES2288578 T3 ES 2288578T3 ES 03009377 T ES03009377 T ES 03009377T ES 03009377 T ES03009377 T ES 03009377T ES 2288578 T3 ES2288578 T3 ES 2288578T3
- Authority
- ES
- Spain
- Prior art keywords
- ray contrast
- polymer
- contrast agent
- component
- zirconyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002639 bone cement Substances 0.000 title claims description 13
- 239000002872 contrast media Substances 0.000 title abstract description 16
- 229920000642 polymer Polymers 0.000 claims abstract description 27
- 229920001577 copolymer Polymers 0.000 claims abstract description 14
- 150000002734 metacrylic acid derivatives Chemical class 0.000 claims abstract description 9
- 238000006116 polymerization reaction Methods 0.000 claims abstract description 9
- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229910052726 zirconium Inorganic materials 0.000 claims abstract description 8
- 239000000203 mixture Substances 0.000 claims description 9
- 239000000178 monomer Substances 0.000 description 9
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 7
- 239000003795 chemical substances by application Substances 0.000 description 7
- 239000000463 material Substances 0.000 description 7
- MCMNRKCIXSYSNV-UHFFFAOYSA-N ZrO2 Inorganic materials O=[Zr]=O MCMNRKCIXSYSNV-UHFFFAOYSA-N 0.000 description 4
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 3
- 229910052788 barium Inorganic materials 0.000 description 3
- DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 description 3
- 229910000389 calcium phosphate Inorganic materials 0.000 description 3
- 239000001506 calcium phosphate Substances 0.000 description 3
- 235000011010 calcium phosphates Nutrition 0.000 description 3
- 239000002131 composite material Substances 0.000 description 3
- 239000000945 filler Substances 0.000 description 3
- 239000003999 initiator Substances 0.000 description 3
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 3
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000004568 cement Substances 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- RVTZCBVAJQQJTK-UHFFFAOYSA-N oxygen(2-);zirconium(4+) Chemical compound [O-2].[O-2].[Zr+4] RVTZCBVAJQQJTK-UHFFFAOYSA-N 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 2
- 229920002959 polymer blend Polymers 0.000 description 2
- 239000004926 polymethyl methacrylate Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 102100026735 Coagulation factor VIII Human genes 0.000 description 1
- 101000911390 Homo sapiens Coagulation factor VIII Proteins 0.000 description 1
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- BOTDANWDWHJENH-UHFFFAOYSA-N Tetraethyl orthosilicate Chemical compound CCO[Si](OCC)(OCC)OCC BOTDANWDWHJENH-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- 229910052586 apatite Inorganic materials 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000005548 dental material Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000013399 early diagnosis Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- IPCAPQRVQMIMAN-UHFFFAOYSA-L zirconyl chloride Chemical compound Cl[Zr](Cl)=O IPCAPQRVQMIMAN-UHFFFAOYSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
- A61L24/0089—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing inorganic fillers not covered by groups A61L24/0078 or A61L24/0084
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
- A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Materials Engineering (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Composite Materials (AREA)
- Gastroenterology & Hepatology (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polymerisation Methods In General (AREA)
- Dental Preparations (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10224346 | 2002-05-29 | ||
| DE10224346 | 2002-05-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2288578T3 true ES2288578T3 (es) | 2008-01-16 |
Family
ID=29414292
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07000986T Expired - Lifetime ES2320043T3 (es) | 2002-05-29 | 2003-04-25 | Cemento oseo y agente de contraste para rayos x y de procedimientos de fabricacion de los mismos. |
| ES03009377T Expired - Lifetime ES2288578T3 (es) | 2002-05-29 | 2003-04-25 | Mezcla para cemento de huesos y agente de contraste de rayos x. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07000986T Expired - Lifetime ES2320043T3 (es) | 2002-05-29 | 2003-04-25 | Cemento oseo y agente de contraste para rayos x y de procedimientos de fabricacion de los mismos. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7091260B2 (zh) |
| EP (2) | EP1366774B1 (zh) |
| JP (1) | JP2003339850A (zh) |
| CN (1) | CN1314455C (zh) |
| AT (2) | ATE417635T1 (zh) |
| AU (1) | AU2003204330B2 (zh) |
| BR (1) | BR0301694A (zh) |
| CA (1) | CA2427370C (zh) |
| CY (2) | CY1107068T1 (zh) |
| DE (2) | DE50310953D1 (zh) |
| DK (2) | DK1366774T3 (zh) |
| ES (2) | ES2320043T3 (zh) |
| PT (2) | PT1782845E (zh) |
| SI (2) | SI1782845T1 (zh) |
| ZA (1) | ZA200304130B (zh) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6689823B1 (en) | 1999-03-31 | 2004-02-10 | The Brigham And Women's Hospital, Inc. | Nanocomposite surgical materials and method of producing them |
| EP1614403B2 (en) | 2003-03-14 | 2014-06-18 | Depuy Spine, Inc. | Hydraulic device for the injection of bone cement in percutaneous vertebroplasty |
| US8066713B2 (en) | 2003-03-31 | 2011-11-29 | Depuy Spine, Inc. | Remotely-activated vertebroplasty injection device |
| US8415407B2 (en) | 2004-03-21 | 2013-04-09 | Depuy Spine, Inc. | Methods, materials, and apparatus for treating bone and other tissue |
| US20070032567A1 (en) * | 2003-06-17 | 2007-02-08 | Disc-O-Tech Medical | Bone Cement And Methods Of Use Thereof |
| WO2005030034A2 (en) * | 2003-09-26 | 2005-04-07 | Depuy Spine, Inc. | Device for delivering viscous material |
| CA2575699C (en) | 2004-07-30 | 2014-07-08 | Disc-O-Tech Medical Technologies Ltd. | Methods, materials and apparatus for treating bone and other tissue |
| US7722620B2 (en) | 2004-12-06 | 2010-05-25 | Dfine, Inc. | Bone treatment systems and methods |
| US9381024B2 (en) * | 2005-07-31 | 2016-07-05 | DePuy Synthes Products, Inc. | Marked tools |
| US9918767B2 (en) | 2005-08-01 | 2018-03-20 | DePuy Synthes Products, Inc. | Temperature control system |
| US8540723B2 (en) | 2009-04-14 | 2013-09-24 | Dfine, Inc. | Medical system and method of use |
| US8777479B2 (en) | 2008-10-13 | 2014-07-15 | Dfine, Inc. | System for use in bone cement preparation and delivery |
| US20070098640A1 (en) * | 2005-11-02 | 2007-05-03 | General Electric Company | Nanoparticle-based imaging agents for X-ray/computed tomography |
| US9149545B2 (en) * | 2005-11-02 | 2015-10-06 | General Electric Company | Nanoparticle-based imaging agents for X-ray/computed tomography and methods for making same |
| US20070122620A1 (en) * | 2005-11-02 | 2007-05-31 | General Electric Company | Nanoparticle-based imaging agents for x-ray / computed tomography and methods for making same |
| US8360629B2 (en) * | 2005-11-22 | 2013-01-29 | Depuy Spine, Inc. | Mixing apparatus having central and planetary mixing elements |
| WO2007106256A2 (en) * | 2006-03-01 | 2007-09-20 | Poly-Med, Inc. | Antimicrobial, radiopaque, microfiber-reinforced, polymeric methacrylate bone cement |
| WO2008032322A2 (en) | 2006-09-14 | 2008-03-20 | Depuy Spine, Inc. | Bone cement and methods of use thereof |
| EP3095511A1 (en) | 2006-10-19 | 2016-11-23 | Depuy Spine Inc. | Sealed container |
| WO2008054204A1 (en) * | 2006-10-31 | 2008-05-08 | Universiteit Maastricht | Two component bone cement composition for vertebroplasty |
| WO2008097855A2 (en) * | 2007-02-05 | 2008-08-14 | Dfine, Inc. | Bone treatment systems and methods |
| WO2008137428A2 (en) | 2007-04-30 | 2008-11-13 | Dfine, Inc. | Bone treatment systems and methods |
| JP2009024068A (ja) * | 2007-07-18 | 2009-02-05 | Nippon Shokubai Co Ltd | 酸化ジルコニウムナノ粒子を含む樹脂粒子の製造方法および樹脂粒子 |
| US20090131886A1 (en) | 2007-11-16 | 2009-05-21 | Liu Y King | Steerable vertebroplasty system |
| US20090131867A1 (en) | 2007-11-16 | 2009-05-21 | Liu Y King | Steerable vertebroplasty system with cavity creation element |
| US9510885B2 (en) | 2007-11-16 | 2016-12-06 | Osseon Llc | Steerable and curvable cavity creation system |
| US9445854B2 (en) | 2008-02-01 | 2016-09-20 | Dfine, Inc. | Bone treatment systems and methods |
| ES2483996T3 (es) | 2008-02-28 | 2014-08-08 | Dfine, Inc. | Sistemas y métodos de tratamiento de los huesos |
| US9180416B2 (en) | 2008-04-21 | 2015-11-10 | Dfine, Inc. | System for use in bone cement preparation and delivery |
| US8133436B2 (en) | 2008-08-05 | 2012-03-13 | Howmedica Osteonics Corp. | Polyethylene cross-linked with an anthocyanin |
| WO2010056811A1 (en) * | 2008-11-12 | 2010-05-20 | Stryker Development, Llc | Tetra calcium phosphate based organophosphorus compositions and methods |
| US20100298832A1 (en) | 2009-05-20 | 2010-11-25 | Osseon Therapeutics, Inc. | Steerable curvable vertebroplasty drill |
| DE102009043551B4 (de) * | 2009-09-30 | 2019-08-14 | Osartis Gmbh | Implantatmaterial sowie Verfahren zu dessen Herstellung |
| BR112012027708B1 (pt) | 2010-04-29 | 2021-03-09 | Dfine, Inc | dispositivo médico para ablação de tecido dentro de um osso de um paciente |
| CA3048850A1 (en) | 2010-05-11 | 2011-11-17 | Howmedica Osteonics Corp. | Organophosphorous, multivalent metal compounds, & polymer adhesive interpenetrating network compositions & methods |
| WO2012099285A1 (ko) * | 2011-01-21 | 2012-07-26 | 서울대학교산학협력단 | 동물뼈를 이용한 나노 세라믹 골시멘트 및 이의 제조 방법 |
| US8765189B2 (en) | 2011-05-13 | 2014-07-01 | Howmedica Osteonic Corp. | Organophosphorous and multivalent metal compound compositions and methods |
| US10219986B2 (en) | 2015-03-04 | 2019-03-05 | Modern Ideas LLC | Stabilized calcium phosphate and methods of forming same |
| US9956314B2 (en) | 2016-01-26 | 2018-05-01 | Modern Ideas LLC | Adhesive for use with bone and bone-like structures |
| EP3531934A4 (en) | 2016-10-27 | 2020-07-15 | Dfine, Inc. | ARTICULATING OSTEOTOME WITH CEMENT DELIVERY CHANNEL |
| US11116570B2 (en) | 2016-11-28 | 2021-09-14 | Dfine, Inc. | Tumor ablation devices and related methods |
| CN110035704B (zh) | 2016-12-09 | 2022-09-06 | Dfine有限公司 | 用于治疗硬组织的医疗装置和相关方法 |
| EP3565486B1 (en) | 2017-01-06 | 2021-11-10 | Dfine, Inc. | Osteotome with a distal portion for simultaneous advancement and articulation |
| DE102018206995A1 (de) * | 2018-05-04 | 2019-11-07 | Merz Dental Gmbh | Härtbares röntgensichtbares Material |
| US11937864B2 (en) | 2018-11-08 | 2024-03-26 | Dfine, Inc. | Ablation systems with parameter-based modulation and related devices and methods |
| US11986229B2 (en) | 2019-09-18 | 2024-05-21 | Merit Medical Systems, Inc. | Osteotome with inflatable portion and multiwire articulation |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3018966A1 (de) * | 1980-05-17 | 1981-12-10 | Bayer Ag, 5090 Leverkusen | Mit organischem material beschichtetes baso (pfeil abwaerts)4(pfeil abwaerts) -pulver |
| US4535485A (en) | 1982-03-12 | 1985-08-20 | Medical Biological Sciences, Inc. | Polymeric acrylic prothesis |
| US6080801A (en) * | 1990-09-13 | 2000-06-27 | Klaus Draenert | Multi-component material and process for its preparation |
| DE4219321A1 (de) | 1992-06-12 | 1993-12-16 | Draenert Klaus | Polymergranulat und Verfahren zu seiner Herstellung |
| GB9410578D0 (en) | 1994-05-26 | 1994-07-13 | London Hospital Med Coll | Novel (meth)acrylate monomers and denture base compositions prepared therefrom |
| EP1163016A2 (en) * | 1999-03-31 | 2001-12-19 | The Brigham And Women's Hospital, Inc. | Nanocomposite surgical materials and method of producing them |
| US6689823B1 (en) * | 1999-03-31 | 2004-02-10 | The Brigham And Women's Hospital, Inc. | Nanocomposite surgical materials and method of producing them |
| US6800245B1 (en) * | 2000-11-28 | 2004-10-05 | Vita Special Purpose Corporation | Sterile polymerizable systems and kits and methods of their manufacture and use |
| US20020118595A1 (en) * | 2001-02-26 | 2002-08-29 | Miller Scott H. | Enclosed implantable material mixing system |
| DE10340800A1 (de) * | 2002-12-20 | 2004-07-01 | Merck Patent Gmbh | Funktionalisierung unreaktiver Substrate |
-
2003
- 2003-04-25 DK DK03009377T patent/DK1366774T3/da active
- 2003-04-25 ES ES07000986T patent/ES2320043T3/es not_active Expired - Lifetime
- 2003-04-25 SI SI200331538T patent/SI1782845T1/sl unknown
- 2003-04-25 EP EP03009377A patent/EP1366774B1/de not_active Expired - Lifetime
- 2003-04-25 EP EP07000986A patent/EP1782845B1/de not_active Expired - Lifetime
- 2003-04-25 DE DE50310953T patent/DE50310953D1/de not_active Expired - Lifetime
- 2003-04-25 PT PT07000986T patent/PT1782845E/pt unknown
- 2003-04-25 DK DK07000986T patent/DK1782845T3/da active
- 2003-04-25 DE DE50307598T patent/DE50307598D1/de not_active Expired - Lifetime
- 2003-04-25 ES ES03009377T patent/ES2288578T3/es not_active Expired - Lifetime
- 2003-04-25 PT PT03009377T patent/PT1366774E/pt unknown
- 2003-04-25 AT AT07000986T patent/ATE417635T1/de not_active IP Right Cessation
- 2003-04-25 SI SI200330950T patent/SI1366774T1/sl unknown
- 2003-04-25 AT AT03009377T patent/ATE366123T1/de not_active IP Right Cessation
- 2003-04-29 US US10/425,337 patent/US7091260B2/en not_active Expired - Fee Related
- 2003-04-29 CA CA002427370A patent/CA2427370C/en not_active Expired - Fee Related
- 2003-05-22 AU AU2003204330A patent/AU2003204330B2/en not_active Ceased
- 2003-05-26 BR BR0301694-3A patent/BR0301694A/pt not_active IP Right Cessation
- 2003-05-27 CN CNB031383505A patent/CN1314455C/zh not_active Expired - Fee Related
- 2003-05-27 JP JP2003149663A patent/JP2003339850A/ja active Pending
- 2003-05-28 ZA ZA200304130A patent/ZA200304130B/xx unknown
-
2007
- 2007-09-05 CY CY20071101152T patent/CY1107068T1/el unknown
-
2009
- 2009-03-17 CY CY20091100296T patent/CY1108888T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1107068T1 (el) | 2012-10-24 |
| ATE366123T1 (de) | 2007-07-15 |
| CA2427370C (en) | 2008-07-08 |
| EP1782845B1 (de) | 2008-12-17 |
| CN1314455C (zh) | 2007-05-09 |
| EP1782845A1 (de) | 2007-05-09 |
| CA2427370A1 (en) | 2003-11-29 |
| CY1108888T1 (el) | 2012-05-23 |
| EP1366774B1 (de) | 2007-07-04 |
| DK1782845T3 (da) | 2009-04-20 |
| DE50310953D1 (de) | 2009-01-29 |
| SI1366774T1 (sl) | 2007-12-31 |
| DK1366774T3 (da) | 2007-10-08 |
| ZA200304130B (en) | 2004-04-05 |
| DE50307598D1 (de) | 2007-08-16 |
| US20040029996A1 (en) | 2004-02-12 |
| BR0301694A (pt) | 2004-08-24 |
| AU2003204330B2 (en) | 2005-10-13 |
| ES2320043T3 (es) | 2009-05-18 |
| US7091260B2 (en) | 2006-08-15 |
| SI1782845T1 (sl) | 2009-06-30 |
| ATE417635T1 (de) | 2009-01-15 |
| AU2003204330A1 (en) | 2003-12-18 |
| CN1461657A (zh) | 2003-12-17 |
| PT1366774E (pt) | 2007-08-16 |
| EP1366774A1 (de) | 2003-12-03 |
| PT1782845E (pt) | 2009-03-24 |
| JP2003339850A (ja) | 2003-12-02 |
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