ES2277931T3 - Tratamiento de la glucogenesis de tipo ii. - Google Patents
Tratamiento de la glucogenesis de tipo ii. Download PDFInfo
- Publication number
- ES2277931T3 ES2277931T3 ES01951000T ES01951000T ES2277931T3 ES 2277931 T3 ES2277931 T3 ES 2277931T3 ES 01951000 T ES01951000 T ES 01951000T ES 01951000 T ES01951000 T ES 01951000T ES 2277931 T3 ES2277931 T3 ES 2277931T3
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- Prior art keywords
- gaa
- glucosidase
- treatment
- acid
- glycogenosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- A61K38/00—Medicinal preparations containing peptides
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- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/0102—Alpha-glucosidase (3.2.1.20)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21923700P | 2000-07-18 | 2000-07-18 | |
| US219237P | 2000-07-18 |
Publications (1)
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|---|---|
| ES2277931T3 true ES2277931T3 (es) | 2007-08-01 |
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| ES01951000T Expired - Lifetime ES2277931T3 (es) | 2000-07-18 | 2001-07-10 | Tratamiento de la glucogenesis de tipo ii. |
| ES07001091.3T Expired - Lifetime ES2523024T3 (es) | 2000-07-18 | 2001-07-10 | Tratamiento de glucogenosis de tipo II |
| ES16178390T Expired - Lifetime ES2700865T3 (es) | 2000-07-18 | 2001-07-10 | Tratamiento de glucogenosis de tipo II |
| ES14167882.1T Expired - Lifetime ES2599401T3 (es) | 2000-07-18 | 2001-07-10 | Tratamiento de glucogenosis de tipo II |
| ES18194771T Expired - Lifetime ES2799882T3 (es) | 2000-07-18 | 2001-07-10 | Tratamiento de glucogenosis de tipo II |
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| Application Number | Title | Priority Date | Filing Date |
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| ES07001091.3T Expired - Lifetime ES2523024T3 (es) | 2000-07-18 | 2001-07-10 | Tratamiento de glucogenosis de tipo II |
| ES16178390T Expired - Lifetime ES2700865T3 (es) | 2000-07-18 | 2001-07-10 | Tratamiento de glucogenosis de tipo II |
| ES14167882.1T Expired - Lifetime ES2599401T3 (es) | 2000-07-18 | 2001-07-10 | Tratamiento de glucogenosis de tipo II |
| ES18194771T Expired - Lifetime ES2799882T3 (es) | 2000-07-18 | 2001-07-10 | Tratamiento de glucogenosis de tipo II |
Country Status (17)
| Country | Link |
|---|---|
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| EP (4) | EP3108895B1 (cg-RX-API-DMAC7.html) |
| JP (10) | JP5113312B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE355075T1 (cg-RX-API-DMAC7.html) |
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| BR (1) | BR0113006A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2416492C (cg-RX-API-DMAC7.html) |
| CY (2) | CY1120977T1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE60126947T2 (cg-RX-API-DMAC7.html) |
| DK (5) | DK3449934T3 (cg-RX-API-DMAC7.html) |
| ES (5) | ES2277931T3 (cg-RX-API-DMAC7.html) |
| LT (3) | LT3108895T (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA03000474A (cg-RX-API-DMAC7.html) |
| PT (5) | PT1301201E (cg-RX-API-DMAC7.html) |
| SI (3) | SI3449934T1 (cg-RX-API-DMAC7.html) |
| TW (1) | TWI280882B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002005841A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (33)
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| CA2416492C (en) * | 2000-07-18 | 2008-04-29 | Duke University | Treatment of glycogen storage disease type ii |
| US7560424B2 (en) * | 2001-04-30 | 2009-07-14 | Zystor Therapeutics, Inc. | Targeted therapeutic proteins |
| US7629309B2 (en) | 2002-05-29 | 2009-12-08 | Zystor Therapeutics, Inc. | Targeted therapeutic proteins |
| WO2002087510A2 (en) * | 2001-04-30 | 2002-11-07 | Symbiontics, Inc. | Subcellular targeting of therapeutic proteins |
| US20040005309A1 (en) * | 2002-05-29 | 2004-01-08 | Symbiontics, Inc. | Targeted therapeutic proteins |
| US6981964B2 (en) | 2001-05-22 | 2006-01-03 | Boston Scientific Scimed, Inc. | Draining bodily fluids with a stent |
| US20030072761A1 (en) * | 2001-10-16 | 2003-04-17 | Lebowitz Jonathan | Methods and compositions for targeting proteins across the blood brain barrier |
| US6733536B1 (en) | 2002-10-22 | 2004-05-11 | Scimed Life Systems | Male urethral stent device |
| PT1587923E (pt) | 2003-01-22 | 2011-12-07 | Univ Duke | Construções melhoradas para a expressão de polipéptidos lisossomais |
| US7442372B2 (en) | 2003-08-29 | 2008-10-28 | Biomarin Pharmaceutical Inc. | Delivery of therapeutic compounds to the brain and other tissues |
| US7129049B2 (en) * | 2003-12-22 | 2006-10-31 | Regents Of The University Of Minnesota | Method of detecting equine glycogen storage disease IV |
| US20050244400A1 (en) * | 2004-02-10 | 2005-11-03 | Zystor Therapeutics, Inc. | Acid alpha-glucosidase and fragments thereof |
| US20050208090A1 (en) * | 2004-03-18 | 2005-09-22 | Medtronic, Inc. | Methods and systems for treatment of neurological diseases of the central nervous system |
| EP1773401B1 (en) * | 2004-06-21 | 2013-01-02 | Medtronic, Inc. | Medical systems and methods for delivering compositions to cells |
| JP2010509344A (ja) * | 2006-11-13 | 2010-03-25 | ザイストール セラピューティクス， インコーポレイテッド | ポンペ病を治療するための方法 |
| WO2009075815A1 (en) | 2007-12-07 | 2009-06-18 | Duke University | Immunomodulating gene therapy |
| CA2723412A1 (en) * | 2008-05-07 | 2009-11-12 | Zystor Therapeutics, Inc. | Lysosomal targeting peptides and uses thereof |
| HUE025212T2 (en) | 2008-07-08 | 2016-03-29 | Univ Duke | A method for treating glycogen storage disease |
| WO2010148253A2 (en) | 2009-06-17 | 2010-12-23 | Zystor Therapeutics, Inc. | Formulations for lysosomal enzymes |
| WO2011139379A2 (en) | 2010-05-06 | 2011-11-10 | Duke University | A method of treating patients undergoing protein replacement therapy, gene replacement therapy, or other therapeutic modalities |
| CN105189542A (zh) | 2013-02-20 | 2015-12-23 | 瓦莱里昂治疗有限责任公司 | 用于治疗庞贝氏症的方法和组合物 |
| CA3209821A1 (en) * | 2013-05-15 | 2014-11-20 | Regents Of The University Of Minnesota | Adeno-associated virus mediated gene transfer to the central nervous system |
| BR112017005810A2 (pt) | 2014-09-30 | 2018-02-27 | Amicus Therapeutics Inc | alfa-glucosidase ácida altamente potente com carboidratos melhorados |
| JP6821192B2 (ja) * | 2015-05-07 | 2021-01-27 | 国立大学法人 東京大学 | ポリイオンコンプレックス型ポリマーソームを用いたナノリアクタとその製造方法 |
| MA44747A (fr) * | 2015-08-31 | 2019-03-06 | Univ Duke | Méthodes et compositions pour le traitement de troubles associés à une accumulation du glycogène cytoplasmique |
| WO2017049157A1 (en) | 2015-09-18 | 2017-03-23 | Duke University | Methods and compositions for the treatment of steatosis-associated disorders |
| IL299470A (en) | 2015-12-30 | 2023-02-01 | Amicus Therapeutics Inc | Improved acid alpha-glucosidase for the treatment of Pompe disease |
| PE20190127A1 (es) | 2016-03-30 | 2019-01-17 | Amicus Therapeutics Inc | Metodo para seleccionar proteinas recombinantes ricas en m6p |
| AU2017239641A1 (en) | 2016-03-30 | 2018-10-18 | Amicus Therapeutics, Inc. | Formulations comprising recombinant acid alpha-glucosidase |
| CA3019427A1 (en) | 2016-04-15 | 2017-10-19 | The Trustees Of The University Of Pennsylvania | Gene therapy for treating mucopolysaccharidosis type ii |
| LT3624831T (lt) | 2017-05-15 | 2023-07-10 | Amicus Therapeutics, Inc. | Rekombinantinė žmogaus rūgštinė alfa-glukozidazė |
| JP7449223B2 (ja) | 2017-09-22 | 2024-03-13 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | ムコ多糖症ｉｉ型を治療するための遺伝子療法 |
| WO2020163480A1 (en) * | 2019-02-05 | 2020-08-13 | Amicus Therapeutics, Inc. | Recombinant human acid alpha-glucosidase and uses thereof |
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| US3063911A (en) * | 1961-04-03 | 1962-11-13 | Taisho Pharmaceutical Co Ltd | Acid-stable digestive enzyme preparation and process of making same |
| US5464778A (en) | 1989-03-08 | 1995-11-07 | Board Of Regents Of The University Of Oklahoma | Glycoprotein ligand for P-selectin and methods of use thereof |
| US5356804A (en) * | 1990-10-24 | 1994-10-18 | Mount Sinai School Of Medicine Of The City Of New York | Cloning and expression of biologically active human α-galactosidase A |
| US6118045A (en) | 1995-08-02 | 2000-09-12 | Pharming B.V. | Lysosomal proteins produced in the milk of transgenic animals |
| CA2328518A1 (en) | 1998-05-13 | 1999-11-18 | Harbor-Ucla | Recombinant (alpha)-l-iduronidase, methods for producing and purifying the same and methods for treating diseases caused by deficiencies thereof |
| ATE410506T1 (de) * | 1998-12-07 | 2008-10-15 | Genzyme Corp | Behandlung der pompeschen krankheit |
| US6642038B1 (en) | 1999-09-14 | 2003-11-04 | Genzyme Glycobiology Research Institute, Inc. | GlcNAc phosphotransferase of the lysosomal targeting pathway |
| CA2416492C (en) * | 2000-07-18 | 2008-04-29 | Duke University | Treatment of glycogen storage disease type ii |
| US7629309B2 (en) | 2002-05-29 | 2009-12-08 | Zystor Therapeutics, Inc. | Targeted therapeutic proteins |
| US20050244400A1 (en) * | 2004-02-10 | 2005-11-03 | Zystor Therapeutics, Inc. | Acid alpha-glucosidase and fragments thereof |
| US8470552B2 (en) | 2009-10-12 | 2013-06-25 | Keck Graduate Institute | Strategy to reduce lactic acid production and control PH in animal cell culture |
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2005
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2007
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2009
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2010
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2011
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2012
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2013
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2016
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- 2018-01-19 US US15/876,086 patent/US10792341B2/en not_active Expired - Fee Related
- 2018-09-13 JP JP2018171154A patent/JP2018199721A/ja active Pending
- 2018-12-07 CY CY181101308T patent/CY1120977T1/el unknown
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2019
- 2019-11-08 JP JP2019202851A patent/JP2020019822A/ja active Pending
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2020
- 2020-06-24 CY CY20201100587T patent/CY1123084T1/el unknown
- 2020-07-27 US US16/940,054 patent/US20210169996A1/en not_active Abandoned
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