ES2266515T3 - Cepa de lactococcus con autocontencion. - Google Patents
Cepa de lactococcus con autocontencion. Download PDFInfo
- Publication number
- ES2266515T3 ES2266515T3 ES02740565T ES02740565T ES2266515T3 ES 2266515 T3 ES2266515 T3 ES 2266515T3 ES 02740565 T ES02740565 T ES 02740565T ES 02740565 T ES02740565 T ES 02740565T ES 2266515 T3 ES2266515 T3 ES 2266515T3
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- lactococcus
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C12Y—ENZYMES
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Animal Behavior & Ethology (AREA)
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01201631 | 2001-05-03 | ||
| EP01201631 | 2001-05-03 | ||
| EP01204785 | 2001-12-07 | ||
| EP01204785 | 2001-12-07 |
Publications (1)
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| ES2266515T3 true ES2266515T3 (es) | 2007-03-01 |
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| ES02740565T Expired - Lifetime ES2266515T3 (es) | 2001-05-03 | 2002-05-03 | Cepa de lactococcus con autocontencion. |
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|---|---|
| EP (1) | EP1383897B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP4347575B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE331789T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2002314040B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2446776C (cg-RX-API-DMAC7.html) |
| DE (1) | DE60212825T2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1383897T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2266515T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002090551A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7780961B2 (en) | 2001-05-03 | 2010-08-24 | Actogenix N.V. | Self-containing Lactococcus strain |
| JP2005529622A (ja) | 2002-06-19 | 2005-10-06 | ヴェーイーベー・ヴェーゼットウェー | 腸吸収を促進するための方法および手段 |
| WO2004056850A2 (en) * | 2002-12-19 | 2004-07-08 | Vib Vzw | Mutant proteins showing increased secretion |
| JP4589618B2 (ja) * | 2003-11-28 | 2010-12-01 | 独立行政法人農業生物資源研究所 | 免疫調節性機能を誘導する乳酸菌類とその成分 |
| US9200249B2 (en) | 2004-08-20 | 2015-12-01 | Actogenix N.V. | Method to improve Lactococcus preservation |
| US8748126B2 (en) * | 2005-11-29 | 2014-06-10 | Actogenix N.V. | Induction of mucosal tolerance to antigens |
| EP2097452A1 (en) * | 2006-12-14 | 2009-09-09 | Actogenix N.V. | Delivery of binding molecules to induce immunomodulation |
| CN101605900B (zh) | 2007-01-12 | 2014-04-23 | 阿克图杰尼斯公司 | 乳球菌启动子和其用途 |
| EP2125010B1 (en) | 2007-01-25 | 2014-06-04 | Actogenix N.V. | Treatment of immune disease by mucosal delivery of antigens using genetically modified lactobacillus |
| WO2010034844A1 (en) * | 2008-09-29 | 2010-04-01 | Actogenix N.V. | Reduced colonization of microbes at the mucosa |
| CA2837634C (en) | 2011-06-01 | 2021-12-14 | Actogenix Nv | Polycistronic expression system for bacteria |
| RU2653757C2 (ru) | 2011-09-23 | 2018-05-14 | Интрексон Актобиотикс Н.В. | Модифицированные грамположительные бактерии и их применение |
| ES2676707T3 (es) | 2011-09-23 | 2018-07-24 | Intrexon Actobiotics Nv | Bacterias gram positivas modificadas y usos de las mismas |
| US9688967B2 (en) | 2014-12-05 | 2017-06-27 | Synlogic, Inc. | Bacteria engineered to treat diseases associated with hyperammonemia |
| US20160206666A1 (en) | 2014-12-22 | 2016-07-21 | Synlogic, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tighten gut mucosal barrier |
| RU2017130462A (ru) * | 2015-03-02 | 2019-04-02 | Синлоджик, Инк. | Бактерия, созданная для лечения заболеваний, облегчаемых при уменьшении воспаления кишечника и/или укреплении мукозного барьера кишечника |
| CN106148254B (zh) * | 2015-03-26 | 2019-11-12 | 南京华贞生物医药科技有限公司 | 一种用于减肥降脂的转化体及其构建方法与应用 |
| SG10202003100XA (en) | 2015-05-13 | 2020-05-28 | Synlogic Operating Co Inc | Bacteria Engineered to Reduce Hyperphenylalaninemia |
| US11685925B2 (en) | 2015-10-30 | 2023-06-27 | Synlogic Operating Company, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tightened gut mucosal barrier |
| ES2925049T3 (es) | 2015-11-16 | 2022-10-13 | Synlogic Operating Co Inc | Bacterias manipuladas para reducir la hiperfenilalaninemia |
| WO2017122180A1 (en) | 2016-01-14 | 2017-07-20 | Intrexon Actobiotics N.V. | Compositions and methods for the treatment of type 1 diabetes |
| CA3035151A1 (en) | 2016-09-02 | 2018-03-08 | Intrexon Actobiotics N.V. | Genetically modified bacteria stably expressing il-10 and insulin |
| IL265177B2 (en) | 2016-09-13 | 2025-01-01 | Intrexon Actobiotics N V | A microorganism that adheres to the mucosa |
| WO2020075171A1 (en) | 2018-10-11 | 2020-04-16 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Bacteria expressing single chain antibodies against toll-like receptors |
| CN114761028A (zh) | 2019-09-27 | 2022-07-15 | 英特瑞克斯顿阿克图比奥帝克斯有限公司 | 乳糜泻的治疗 |
| JP2023518184A (ja) | 2020-03-20 | 2023-04-28 | シンロジック オペレーティング カンパニー インコーポレイテッド | 高フェニルアラニン血症を軽減するように遺伝子改変された微生物 |
Family Cites Families (1)
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| DE4231764A1 (de) * | 1992-09-23 | 1994-03-24 | Inst Pflanzengenetik & Kultur | Verfahren zur chromosomalen Integration eines Produkt-Gens |
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- 2002-05-03 AU AU2002314040A patent/AU2002314040B2/en not_active Ceased
- 2002-05-03 DE DE60212825T patent/DE60212825T2/de not_active Expired - Lifetime
- 2002-05-03 ES ES02740565T patent/ES2266515T3/es not_active Expired - Lifetime
- 2002-05-03 AT AT02740565T patent/ATE331789T1/de active
- 2002-05-03 JP JP2002587611A patent/JP4347575B2/ja not_active Expired - Fee Related
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- 2002-05-03 DK DK02740565T patent/DK1383897T3/da active
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2008
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Also Published As
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| CA2446776A1 (en) | 2002-11-14 |
| JP2004533246A (ja) | 2004-11-04 |
| EP1383897B1 (en) | 2006-06-28 |
| WO2002090551A3 (en) | 2003-03-27 |
| JP2009060913A (ja) | 2009-03-26 |
| EP1383897A2 (en) | 2004-01-28 |
| ATE331789T1 (de) | 2006-07-15 |
| AU2002314040B2 (en) | 2007-06-28 |
| CA2446776C (en) | 2011-07-12 |
| DE60212825T2 (de) | 2007-01-11 |
| DE60212825D1 (de) | 2006-08-10 |
| JP4347575B2 (ja) | 2009-10-21 |
| WO2002090551A2 (en) | 2002-11-14 |
| DK1383897T3 (da) | 2006-10-30 |
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